KR102705724B1 - 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸 - Google Patents

신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸 Download PDF

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KR102705724B1
KR102705724B1 KR1020237022665A KR20237022665A KR102705724B1 KR 102705724 B1 KR102705724 B1 KR 102705724B1 KR 1020237022665 A KR1020237022665 A KR 1020237022665A KR 20237022665 A KR20237022665 A KR 20237022665A KR 102705724 B1 KR102705724 B1 KR 102705724B1
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pyrazol
disease
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KR20230107407A (ko
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앤서니 에이. 에스트라다
지안웬 에이. 펭
조셉 피. 리시카토스
자카리 케이. 스위니
자비에르 드 비센테 피달고
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데날리 테라퓨틱스 인크.
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KR1020237022665A 2016-06-16 2017-06-15 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸 Active KR102705724B1 (ko)

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KR1020247029993A KR102843750B1 (ko) 2016-06-16 2017-06-15 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸

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Application Number Priority Date Filing Date Title
US201662350876P 2016-06-16 2016-06-16
US62/350,876 2016-06-16
US201662417151P 2016-11-03 2016-11-03
US62/417,151 2016-11-03
US201762476581P 2017-03-24 2017-03-24
US62/476,581 2017-03-24
US201762510711P 2017-05-24 2017-05-24
US62/510,711 2017-05-24
PCT/US2017/037782 WO2017218843A1 (en) 2016-06-16 2017-06-15 Pyrimidin-2-ylamino-1h-pyrazols as lrrk2 inhibitors for use in the treatment of neurodegenerative disorders
KR1020197000749A KR102553188B1 (ko) 2016-06-16 2017-06-15 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸

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KR20230107407A KR20230107407A (ko) 2023-07-14
KR102705724B1 true KR102705724B1 (ko) 2024-09-12

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KR1020237022665A Active KR102705724B1 (ko) 2016-06-16 2017-06-15 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸
KR1020247029993A Active KR102843750B1 (ko) 2016-06-16 2017-06-15 신경퇴행성 장애의 치료에서 사용하기 위한 lrrk2 저해제로서 피리미딘-2-일아미노-1h-피라졸

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CN115894456A (zh) * 2022-11-13 2023-04-04 药康众拓(江苏)医药科技有限公司 一种氘代吡唑氨基嘧啶类化合物、药物组合物和用途
KR20250102043A (ko) 2022-11-22 2025-07-04 데날리 테라퓨틱스 인크. 피리미딘 아미노피라졸 화합물의 제조 방법 및 중간체
CN115819405A (zh) * 2022-12-20 2023-03-21 沪渝人工智能研究院 嘧啶氨基吡唑衍生物及其作为富亮氨酸重复激酶2抑制剂的应用
CN119968373A (zh) * 2023-09-07 2025-05-09 上海翊石医药科技有限公司 一种芳杂环类化合物及其制备方法
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