KR102606948B1 - 안구 건조증을 치료하거나 예방하는 방법 - Google Patents

안구 건조증을 치료하거나 예방하는 방법 Download PDF

Info

Publication number
KR102606948B1
KR102606948B1 KR1020187000291A KR20187000291A KR102606948B1 KR 102606948 B1 KR102606948 B1 KR 102606948B1 KR 1020187000291 A KR1020187000291 A KR 1020187000291A KR 20187000291 A KR20187000291 A KR 20187000291A KR 102606948 B1 KR102606948 B1 KR 102606948B1
Authority
KR
South Korea
Prior art keywords
dry eye
formula
compound
eye
ngf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020187000291A
Other languages
English (en)
Korean (ko)
Other versions
KR20180019151A (ko
Inventor
롱-쭌 우
린-예 홍
Original Assignee
롱-쭌 우
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 롱-쭌 우 filed Critical 롱-쭌 우
Publication of KR20180019151A publication Critical patent/KR20180019151A/ko
Application granted granted Critical
Publication of KR102606948B1 publication Critical patent/KR102606948B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020187000291A 2015-06-16 2016-06-16 안구 건조증을 치료하거나 예방하는 방법 Active KR102606948B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562180450P 2015-06-16 2015-06-16
US62/180,450 2015-06-16
PCT/CN2016/000309 WO2016201953A1 (en) 2015-06-16 2016-06-16 Method for treating or preventing dry eyes

Publications (2)

Publication Number Publication Date
KR20180019151A KR20180019151A (ko) 2018-02-23
KR102606948B1 true KR102606948B1 (ko) 2023-11-27

Family

ID=57544797

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187000291A Active KR102606948B1 (ko) 2015-06-16 2016-06-16 안구 건조증을 치료하거나 예방하는 방법

Country Status (9)

Country Link
US (1) US10383885B2 (https=)
EP (1) EP3310361B1 (https=)
JP (1) JP6960399B2 (https=)
KR (1) KR102606948B1 (https=)
CN (1) CN107921053B (https=)
AU (1) AU2016279139B2 (https=)
CA (1) CA2989341C (https=)
TW (1) TWI649083B (https=)
WO (1) WO2016201953A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332726A (zh) * 1998-11-02 2002-01-23 卫福有限公司 吡咯烷化合物及其药物用途
NZ517556A (en) * 1999-09-06 2003-08-29 Ono Pharmaceutical Co N-[o-(p-pivaloyloxybenzenesulphonyl-amino)benzoyl]glycine as preventive and therapeutic agents for eye diseases
CN1257176C (zh) * 2003-10-24 2006-05-24 广州中医药大学热带医学研究所 2，3，5，4＇－四羟基二苯乙烯－2－O－β－D－葡萄糖苷在制备降血脂药物中的应用
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20100160243A1 (en) * 2008-12-24 2010-06-24 National Yang-Ming University Compounds and methods for enhancing erythropoiesis
CN101966193B (zh) * 2010-10-29 2012-05-23 西南交通大学 2,3,5,4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在制备治疗抑郁症药物中的应用
US20120164242A1 (en) * 2010-12-27 2012-06-28 Wen-Jen Yu Novel methods for modulating melanin production
AU2013384234A1 (en) * 2013-03-28 2015-10-15 Rong-Tsun Wu Composition and method for inducing EPO-mediated haemoglobin expression and mitochondrial biogenesis in nonhaematopoietic cell
CN103524576A (zh) * 2013-08-12 2014-01-22 天津中医药大学 2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的分离纯化工艺

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Antonio Abengózar-Vela et al. Quercetin and Resveratrol Decrease the Inflammatory and Oxidative Responses in Human Ocular Surface Epithelial Cells. Biochemistry and Molecular Bilogy, v.56 pp.2709-2719

Also Published As

Publication number Publication date
KR20180019151A (ko) 2018-02-23
AU2016279139B2 (en) 2020-09-10
EP3310361A1 (en) 2018-04-25
CA2989341C (en) 2021-12-07
JP6960399B2 (ja) 2021-11-05
TW201717965A (zh) 2017-06-01
AU2016279139A1 (en) 2018-01-04
EP3310361A4 (en) 2019-01-23
WO2016201953A1 (en) 2016-12-22
TWI649083B (zh) 2019-02-01
CN107921053A (zh) 2018-04-17
US10383885B2 (en) 2019-08-20
JP2018517776A (ja) 2018-07-05
US20180193369A1 (en) 2018-07-12
CA2989341A1 (en) 2016-12-22
CN107921053B (zh) 2020-09-01
EP3310361B1 (en) 2022-05-11

Similar Documents

Publication Publication Date Title
US9925201B2 (en) Compositions and treatment for eye diseases and disorders
Cholkar et al. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045)
US20240374540A1 (en) Formulations for the treatment of ocular surface diseases and related methods
KR102578102B1 (ko) 엔도텔린 수용체 길항제의 국소 안용 제형
KR102606948B1 (ko) 안구 건조증을 치료하거나 예방하는 방법
CN115884782B (zh) 新型干眼症治疗用药物组合物
CN107137698A (zh) 一种包含gdnf的用于治疗角膜上皮损伤的药物组合物
JP2023518179A (ja) ドライアイ疾患、網膜変性疾患、又は眼の炎症の治療のための抗老化グリコペプチドの使用
US20250360185A1 (en) Compositions comprising pedf-derived short peptides for the treatment of dry eye diseases
WO2025140240A1 (zh) 一种用于治疗和/或预防角膜损伤的药物组合物和方法
WO2023048174A1 (ja) 角膜疾患治療剤
CN111632128A (zh) 短链胜肽组合物在预防或治疗干眼症的应用

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20180104

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210414

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230701

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20231018

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20231123

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20231123

End annual number: 3

Start annual number: 1

PG1601 Publication of registration