CN107921053B - 用于治疗或预防干眼症的方法 - Google Patents

用于治疗或预防干眼症的方法 Download PDF

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Publication number
CN107921053B
CN107921053B CN201680035333.5A CN201680035333A CN107921053B CN 107921053 B CN107921053 B CN 107921053B CN 201680035333 A CN201680035333 A CN 201680035333A CN 107921053 B CN107921053 B CN 107921053B
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China
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dry eye
general formula
compound
eye
tear
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CN201680035333.5A
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Chinese (zh)
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CN107921053A (zh
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吴荣灿
洪琳雅
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201680035333.5A 2015-06-16 2016-06-16 用于治疗或预防干眼症的方法 Active CN107921053B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562180450P 2015-06-16 2015-06-16
US62/180,450 2015-06-16
PCT/CN2016/000309 WO2016201953A1 (en) 2015-06-16 2016-06-16 Method for treating or preventing dry eyes

Publications (2)

Publication Number Publication Date
CN107921053A CN107921053A (zh) 2018-04-17
CN107921053B true CN107921053B (zh) 2020-09-01

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ID=57544797

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CN201680035333.5A Active CN107921053B (zh) 2015-06-16 2016-06-16 用于治疗或预防干眼症的方法

Country Status (9)

Country Link
US (1) US10383885B2 (https=)
EP (1) EP3310361B1 (https=)
JP (1) JP6960399B2 (https=)
KR (1) KR102606948B1 (https=)
CN (1) CN107921053B (https=)
AU (1) AU2016279139B2 (https=)
CA (1) CA2989341C (https=)
TW (1) TWI649083B (https=)
WO (1) WO2016201953A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332726A (zh) * 1998-11-02 2002-01-23 卫福有限公司 吡咯烷化合物及其药物用途
NZ517556A (en) * 1999-09-06 2003-08-29 Ono Pharmaceutical Co N-[o-(p-pivaloyloxybenzenesulphonyl-amino)benzoyl]glycine as preventive and therapeutic agents for eye diseases
CN1257176C (zh) * 2003-10-24 2006-05-24 广州中医药大学热带医学研究所 2，3，5，4＇－四羟基二苯乙烯－2－O－β－D－葡萄糖苷在制备降血脂药物中的应用
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20100160243A1 (en) * 2008-12-24 2010-06-24 National Yang-Ming University Compounds and methods for enhancing erythropoiesis
CN101966193B (zh) * 2010-10-29 2012-05-23 西南交通大学 2,3,5,4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在制备治疗抑郁症药物中的应用
US20120164242A1 (en) * 2010-12-27 2012-06-28 Wen-Jen Yu Novel methods for modulating melanin production
AU2013384234A1 (en) * 2013-03-28 2015-10-15 Rong-Tsun Wu Composition and method for inducing EPO-mediated haemoglobin expression and mitochondrial biogenesis in nonhaematopoietic cell
CN103524576A (zh) * 2013-08-12 2014-01-22 天津中医药大学 2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的分离纯化工艺

Also Published As

Publication number Publication date
KR20180019151A (ko) 2018-02-23
AU2016279139B2 (en) 2020-09-10
EP3310361A1 (en) 2018-04-25
CA2989341C (en) 2021-12-07
JP6960399B2 (ja) 2021-11-05
TW201717965A (zh) 2017-06-01
AU2016279139A1 (en) 2018-01-04
EP3310361A4 (en) 2019-01-23
WO2016201953A1 (en) 2016-12-22
TWI649083B (zh) 2019-02-01
CN107921053A (zh) 2018-04-17
US10383885B2 (en) 2019-08-20
JP2018517776A (ja) 2018-07-05
US20180193369A1 (en) 2018-07-12
CA2989341A1 (en) 2016-12-22
KR102606948B1 (ko) 2023-11-27
EP3310361B1 (en) 2022-05-11

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