KR102594130B1 - 편두통 치료 - Google Patents

편두통 치료 Download PDF

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Publication number
KR102594130B1
KR102594130B1 KR1020197038730A KR20197038730A KR102594130B1 KR 102594130 B1 KR102594130 B1 KR 102594130B1 KR 1020197038730 A KR1020197038730 A KR 1020197038730A KR 20197038730 A KR20197038730 A KR 20197038730A KR 102594130 B1 KR102594130 B1 KR 102594130B1
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KR
South Korea
Prior art keywords
delete delete
migraine
leucine
pharmaceutical composition
acetyl
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KR1020197038730A
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English (en)
Korean (ko)
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KR20210013518A (ko
Inventor
마이클 스트럽
말로리 팩터
Original Assignee
인트라바이오 리미티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59358204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102594130(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
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Publication of KR20210013518A publication Critical patent/KR20210013518A/ko
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Publication of KR102594130B1 publication Critical patent/KR102594130B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197038730A 2017-06-14 2018-06-25 편두통 치료 Active KR102594130B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1709459.0A GB201709459D0 (en) 2017-06-14 2017-06-14 Treatment for migraine
PCT/IB2018/054676 WO2018229738A1 (en) 2017-06-14 2018-06-25 Treatment for migraine

Publications (2)

Publication Number Publication Date
KR20210013518A KR20210013518A (ko) 2021-02-04
KR102594130B1 true KR102594130B1 (ko) 2023-10-24

Family

ID=59358204

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197038730A Active KR102594130B1 (ko) 2017-06-14 2018-06-25 편두통 치료

Country Status (25)

Country Link
US (1) US11471434B2 (cg-RX-API-DMAC10.html)
EP (1) EP3638370B1 (cg-RX-API-DMAC10.html)
JP (1) JP7130739B2 (cg-RX-API-DMAC10.html)
KR (1) KR102594130B1 (cg-RX-API-DMAC10.html)
CN (1) CN111093772B (cg-RX-API-DMAC10.html)
AU (1) AU2018284330B2 (cg-RX-API-DMAC10.html)
CY (1) CY1123860T1 (cg-RX-API-DMAC10.html)
DK (1) DK3638370T3 (cg-RX-API-DMAC10.html)
ES (1) ES2847169T3 (cg-RX-API-DMAC10.html)
GB (1) GB201709459D0 (cg-RX-API-DMAC10.html)
HR (1) HRP20210108T1 (cg-RX-API-DMAC10.html)
HU (1) HUE053089T2 (cg-RX-API-DMAC10.html)
IL (1) IL271211B2 (cg-RX-API-DMAC10.html)
LT (1) LT3638370T (cg-RX-API-DMAC10.html)
MA (1) MA49396B1 (cg-RX-API-DMAC10.html)
MD (1) MD3638370T2 (cg-RX-API-DMAC10.html)
MX (1) MX387909B (cg-RX-API-DMAC10.html)
PL (1) PL3638370T3 (cg-RX-API-DMAC10.html)
PT (1) PT3638370T (cg-RX-API-DMAC10.html)
RS (1) RS61481B1 (cg-RX-API-DMAC10.html)
SG (1) SG11201912146RA (cg-RX-API-DMAC10.html)
SI (1) SI3638370T1 (cg-RX-API-DMAC10.html)
SM (1) SMT202100037T1 (cg-RX-API-DMAC10.html)
WO (1) WO2018229738A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201908087B (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS65663B1 (sr) 2018-02-15 2024-07-31 Intrabio Ltd Acetil leucin za upotrebu u lečenju sindroma nemirnih nogu
CN120157593A (zh) * 2018-12-06 2025-06-17 内在生物技术有限公司 乙酰基-亮氨酸的氘代类似物
MD3989962T2 (ro) 2019-06-28 2025-12-31 Intrabio Ltd Gb Terapie combinată cu acetil-leucină și miglustat pentru tratamentul unei boli de depozitare lizozomală
WO2021144720A1 (en) 2020-01-13 2021-07-22 Intrabio Ltd Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012064892A1 (en) 2010-11-09 2012-05-18 Mannkind Corporation Composition comprising a serotonin receptor agonist and a diketopiperazine for treating migraines

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
SE8701662L (sv) * 1987-04-22 1988-10-23 Gelder Nico M Van Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna
US20040127501A1 (en) * 2002-09-24 2004-07-01 Zhengming Chen Therapeutic agents useful for treating pain
US20060063827A1 (en) 2004-09-23 2006-03-23 Yu Ruey J Systemic administration of therapeutic amino acids and N-acetylamino acids
AR044688A1 (es) * 2003-06-12 2005-09-21 Euro Celtique Sa Agentes terapeuticos utiles para el tratamiento del dolor
ES2322707T3 (es) * 2003-07-03 2009-06-25 Euro-Celtique S.A. Derivados de 2-piridina alquino utiles para tratar el dolor.
ES2327684T3 (es) * 2003-07-24 2009-11-02 Euro-Celtique S.A. Compuestos heteroaril-tetrahidropiridilo utiles para el tratamiento o la prevencion del dolor.
SI1664041T1 (sl) * 2003-09-22 2008-12-31 Euro Celtique Sa Fenil-karboksamidne spojine, uporabne za tretiranje bolečine
MXPA06003123A (es) * 2003-09-22 2006-05-31 Euro Celtique Sa Agentes terapeuticos utiles para el tratamiento del dolor.
ES2322907T3 (es) * 2003-12-30 2009-07-01 Euro-Celtique S.A. Piperazinas utiles para el tratamiento de dolor.
FR2905600B1 (fr) 2006-09-13 2010-01-15 Pf Medicament Traitement des vertiges par l'acetyl-l-leucine.
TN2010000251A1 (fr) 2010-06-03 2011-11-11 Rekik Raouf N-acetyl-dl-leucine medicament neuro et retino protecteur
US8921373B2 (en) * 2010-06-22 2014-12-30 Shionogi & Co., Ltd. Compounds having TRPV1 antagonistic activity and uses thereof
CA2803166C (en) 2010-06-25 2023-03-07 Shire Human Genetic Therapies, Inc. Cns delivery of therapeutic agents
US9394293B2 (en) * 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
PT3445351T (pt) 2016-04-19 2024-11-14 Intrabio Ltd Acetil-leucina ou um sal farmaceuticamente aceitável seu derivado para melhoria da mobilidade
TN2019000033A1 (fr) 2016-08-11 2020-07-15 Intrabio Ltd Agents thérapeutiques pour maladies neurodégénératives
PT3482754T (pt) 2016-08-11 2021-02-03 Intrabio Ltd Composições farmacêuticas e utilizações contra os distúrbios de armazenamento lisossómico
PT3600276T (pt) 2017-03-28 2023-07-11 Intrabio Ltd Beta-histina, ou um seu sal farmaceuticamente aceitável, e um inibidor da monoamina oxidase, para utilização no tratamento ou prevenção de um ou mais sintomas de vertigem num indivíduo
US11793782B2 (en) 2017-10-18 2023-10-24 Intrabio Limited Therapeutic agents for neurodegenerative diseases
EP3697406A1 (en) 2017-10-18 2020-08-26 IntraBio Ltd Therapeutic agents for improved mobility and cognitive function and for treating neurodegenerative diseases and lysosomal storage disorders
RS65663B1 (sr) 2018-02-15 2024-07-31 Intrabio Ltd Acetil leucin za upotrebu u lečenju sindroma nemirnih nogu
CN120157593A (zh) 2018-12-06 2025-06-17 内在生物技术有限公司 乙酰基-亮氨酸的氘代类似物
CN119097618A (zh) 2019-03-02 2024-12-10 内在生物技术有限公司 用于治疗疾病的亮氨酸、乙酰基亮氨酸和相关类似物
MD3989962T2 (ro) 2019-06-28 2025-12-31 Intrabio Ltd Gb Terapie combinată cu acetil-leucină și miglustat pentru tratamentul unei boli de depozitare lizozomală
WO2021144720A1 (en) 2020-01-13 2021-07-22 Intrabio Ltd Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012064892A1 (en) 2010-11-09 2012-05-18 Mannkind Corporation Composition comprising a serotonin receptor agonist and a diketopiperazine for treating migraines

Also Published As

Publication number Publication date
AU2018284330A1 (en) 2020-01-02
CA3067321A1 (en) 2018-12-20
JP2020526575A (ja) 2020-08-31
ES2847169T3 (es) 2021-08-02
MD3638370T2 (ro) 2021-04-30
CN111093772B (zh) 2023-11-03
IL271211B2 (en) 2024-01-01
RU2020100475A3 (cg-RX-API-DMAC10.html) 2021-10-22
DK3638370T3 (da) 2021-01-25
HUE053089T2 (hu) 2021-06-28
AU2018284330B2 (en) 2024-03-14
SI3638370T1 (sl) 2021-04-30
WO2018229738A1 (en) 2018-12-20
ZA201908087B (en) 2024-11-27
BR112019026660A2 (pt) 2020-07-14
HRP20210108T1 (hr) 2021-03-19
SG11201912146RA (en) 2020-01-30
RS61481B1 (sr) 2021-03-31
RU2020100475A (ru) 2021-07-14
MA49396A (fr) 2020-04-22
CN111093772A (zh) 2020-05-01
EP3638370B1 (en) 2020-11-11
SMT202100037T1 (it) 2021-03-15
US20200253905A1 (en) 2020-08-13
LT3638370T (lt) 2021-03-25
KR20210013518A (ko) 2021-02-04
MA49396B1 (fr) 2021-03-31
MX2019014784A (es) 2021-11-16
IL271211A (en) 2020-01-30
EP3638370A1 (en) 2020-04-22
PT3638370T (pt) 2021-01-26
JP7130739B2 (ja) 2022-09-05
CY1123860T1 (el) 2022-05-27
IL271211B1 (en) 2023-09-01
PL3638370T3 (pl) 2021-05-17
US11471434B2 (en) 2022-10-18
GB201709459D0 (en) 2017-07-26
MX387909B (es) 2025-03-19

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