KR102531892B1 - 바이오반응기 공정의 제어 - Google Patents

바이오반응기 공정의 제어 Download PDF

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KR102531892B1
KR102531892B1 KR1020177002806A KR20177002806A KR102531892B1 KR 102531892 B1 KR102531892 B1 KR 102531892B1 KR 1020177002806 A KR1020177002806 A KR 1020177002806A KR 20177002806 A KR20177002806 A KR 20177002806A KR 102531892 B1 KR102531892 B1 KR 102531892B1
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culture medium
flow rate
measured
bioreactor
concentration
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Korean (ko)
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KR20170028389A (ko
Inventor
크리스토프 콜릿
가이 윌리엄 워터스
제이슨 칼 브롬리
저스틴 이 양
제로드 나단 윌슨
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란자테크 엔지, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/12—Bioreactors or fermenters specially adapted for specific uses for producing fuels or solvents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Hardware Design (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020177002806A 2014-07-11 2015-05-06 바이오반응기 공정의 제어 Active KR102531892B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/329,881 US9617566B2 (en) 2014-07-11 2014-07-11 Control of bioreactor processes
US14/329,881 2014-07-11
PCT/US2015/029563 WO2016007216A1 (en) 2014-07-11 2015-05-06 Control of bioreactor processes

Publications (2)

Publication Number Publication Date
KR20170028389A KR20170028389A (ko) 2017-03-13
KR102531892B1 true KR102531892B1 (ko) 2023-05-11

Family

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Application Number Title Priority Date Filing Date
KR1020177002806A Active KR102531892B1 (ko) 2014-07-11 2015-05-06 바이오반응기 공정의 제어

Country Status (13)

Country Link
US (2) US9617566B2 (https=)
EP (2) EP3766983A1 (https=)
JP (2) JP6599427B2 (https=)
KR (1) KR102531892B1 (https=)
CN (1) CN106574276B (https=)
BR (1) BR112017000449B1 (https=)
CA (2) CA3024631C (https=)
EA (1) EA033036B1 (https=)
ES (1) ES2841337T3 (https=)
PL (1) PL3167068T3 (https=)
PT (1) PT3167068T (https=)
TW (2) TWI649426B (https=)
WO (1) WO2016007216A1 (https=)

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US10017789B2 (en) 2015-03-25 2018-07-10 The Board Of Regents For Oklahoma State University System and method for feedback control of gas supply for ethanol production via syngas fermentation using pH as a key control indicator
US10167445B2 (en) * 2016-04-04 2019-01-01 Hong Peng Cell culture monitoring system with low power consumption
CN111051517B (zh) * 2017-09-08 2023-10-27 朗泽科技有限公司 用于使用富氢气的含有c1的底物生产代谢物的方法和系统
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
JP7520322B2 (ja) 2018-02-09 2024-07-23 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 細胞療法のためのバイオプロセッシング方法
KR102276219B1 (ko) * 2019-02-15 2021-07-12 씨제이제일제당 (주) 생물반응기의 운전 조건을 결정하는 장치 및 방법
KR102494796B1 (ko) * 2020-04-20 2023-02-01 현대제철 주식회사 바이오 연료 제조방법
JP2024513395A (ja) 2021-04-09 2024-03-25 ランザテク，インコーポレイテッド 供給原料を提供するためのプロセス及び装置

Citations (1)

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US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
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NZ560757A (en) 2007-10-28 2010-07-30 Lanzatech New Zealand Ltd Improved carbon capture in microbial fermentation of industrial gases to ethanol
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KR101950042B1 (ko) * 2010-12-03 2019-02-19 이네오스 바이오 에스에이 비 co-흡수 조절을 포함하는 발효 방법
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JP2013514804A (ja) 2009-12-22 2013-05-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ バイオリアクター内の培養パラメーターの制御方法

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US20160010116A1 (en) 2016-01-14
CA2954496A1 (en) 2016-01-14
BR112017000449B1 (pt) 2022-10-25
TWI673366B (zh) 2019-10-01
TW201920688A (zh) 2019-06-01
WO2016007216A1 (en) 2016-01-14
CN106574276B (zh) 2020-11-06
CA3024631C (en) 2022-03-15
EP3167068B1 (en) 2020-10-28
CA2954496C (en) 2019-01-08
CA3024631A1 (en) 2016-01-14
KR20170028389A (ko) 2017-03-13
EP3167068A4 (en) 2018-03-21
EA033036B1 (ru) 2019-08-30
PT3167068T (pt) 2020-12-21
EP3167068A1 (en) 2017-05-17
US20170175064A1 (en) 2017-06-22
TWI649426B (zh) 2019-02-01
JP2019193636A (ja) 2019-11-07
US9617566B2 (en) 2017-04-11
TW201625801A (zh) 2016-07-16
JP6955531B2 (ja) 2021-10-27
US11753612B2 (en) 2023-09-12
PL3167068T3 (pl) 2021-04-19
BR112017000449A2 (pt) 2017-11-07
EA201790136A1 (ru) 2017-05-31
JP2017521077A (ja) 2017-08-03
JP6599427B2 (ja) 2019-10-30
EP3766983A1 (en) 2021-01-20
ES2841337T3 (es) 2021-07-08
CN106574276A (zh) 2017-04-19

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