JP6599427B2 - バイオリアクタプロセスの制御 - Google Patents

バイオリアクタプロセスの制御 Download PDF

Info

Publication number
JP6599427B2
JP6599427B2 JP2017501279A JP2017501279A JP6599427B2 JP 6599427 B2 JP6599427 B2 JP 6599427B2 JP 2017501279 A JP2017501279 A JP 2017501279A JP 2017501279 A JP2017501279 A JP 2017501279A JP 6599427 B2 JP6599427 B2 JP 6599427B2
Authority
JP
Japan
Prior art keywords
concentration
measured
productivity
culture
flow rate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017501279A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017521077A5 (https=
JP2017521077A (ja
Inventor
コレット，クリストフ
ウィリアム ウォーターズ，ガイ
カール ブロムリー，ジェーソン
イー ヤング，ジャスティン
ネイサン ウィルソン，ジャロッド
Original Assignee
ランザテク・ニュージーランド・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ランザテク・ニュージーランド・リミテッド filed Critical ランザテク・ニュージーランド・リミテッド
Publication of JP2017521077A publication Critical patent/JP2017521077A/ja
Publication of JP2017521077A5 publication Critical patent/JP2017521077A5/ja
Priority to JP2019100536A priority Critical patent/JP6955531B2/ja
Application granted granted Critical
Publication of JP6599427B2 publication Critical patent/JP6599427B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/12—Bioreactors or fermenters specially adapted for specific uses for producing fuels or solvents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Hardware Design (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017501279A 2014-07-11 2015-05-06 バイオリアクタプロセスの制御 Active JP6599427B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019100536A JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/329,881 US9617566B2 (en) 2014-07-11 2014-07-11 Control of bioreactor processes
US14/329,881 2014-07-11
PCT/US2015/029563 WO2016007216A1 (en) 2014-07-11 2015-05-06 Control of bioreactor processes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019100536A Division JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Publications (3)

Publication Number Publication Date
JP2017521077A JP2017521077A (ja) 2017-08-03
JP2017521077A5 JP2017521077A5 (https=) 2018-06-21
JP6599427B2 true JP6599427B2 (ja) 2019-10-30

Family

ID=55064652

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017501279A Active JP6599427B2 (ja) 2014-07-11 2015-05-06 バイオリアクタプロセスの制御
JP2019100536A Active JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019100536A Active JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Country Status (13)

Country Link
US (2) US9617566B2 (https=)
EP (2) EP3766983A1 (https=)
JP (2) JP6599427B2 (https=)
KR (1) KR102531892B1 (https=)
CN (1) CN106574276B (https=)
BR (1) BR112017000449B1 (https=)
CA (2) CA3024631C (https=)
EA (1) EA033036B1 (https=)
ES (1) ES2841337T3 (https=)
PL (1) PL3167068T3 (https=)
PT (1) PT3167068T (https=)
TW (2) TWI649426B (https=)
WO (1) WO2016007216A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017789B2 (en) 2015-03-25 2018-07-10 The Board Of Regents For Oklahoma State University System and method for feedback control of gas supply for ethanol production via syngas fermentation using pH as a key control indicator
US10167445B2 (en) * 2016-04-04 2019-01-01 Hong Peng Cell culture monitoring system with low power consumption
CN111051517B (zh) * 2017-09-08 2023-10-27 朗泽科技有限公司 用于使用富氢气的含有c1的底物生产代谢物的方法和系统
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
JP7520322B2 (ja) 2018-02-09 2024-07-23 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 細胞療法のためのバイオプロセッシング方法
KR102276219B1 (ko) * 2019-02-15 2021-07-12 씨제이제일제당 (주) 생물반응기의 운전 조건을 결정하는 장치 및 방법
KR102494796B1 (ko) * 2020-04-20 2023-02-01 현대제철 주식회사 바이오 연료 제조방법
JP2024513395A (ja) 2021-04-09 2024-03-25 ランザテク，インコーポレイテッド 供給原料を提供するためのプロセス及び装置

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
JP2002526750A (ja) 1998-10-02 2002-08-20 ワトキンス，ウィリアム，ブルース，キャンベル 圧迫ガーメントを寸法設定するための測定器具及び測定方法
WO2000068407A1 (en) 1999-05-07 2000-11-16 Bioengineering Resources, Inc. Clostridium strains which produce ethanol from substrate-containing gases
WO2002008438A2 (en) * 2000-07-25 2002-01-31 Bioengineering Resources, Inc. Methods for increasing the production of ethanol from microbial fermentation
US20090104594A1 (en) * 2004-12-29 2009-04-23 Biogen Idec Bioreactor Process Control System and Method
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
CN102016052B (zh) * 2007-08-15 2015-04-29 朗泽科技新西兰有限公司 生产醇的工艺
NZ560757A (en) 2007-10-28 2010-07-30 Lanzatech New Zealand Ltd Improved carbon capture in microbial fermentation of industrial gases to ethanol
EA019266B1 (ru) 2008-03-12 2014-02-28 Ланзатек Нью Зиленд Лимитед Микробиологический способ производства спирта
CN102361989B (zh) 2009-01-29 2014-03-12 兰扎泰克新西兰有限公司 醇的生产方法
EP2449121B1 (en) * 2009-07-02 2020-09-02 Lanzatech New Zealand Limited Alcohol production process
US20120258441A1 (en) * 2009-12-22 2012-10-11 Ge Healthcare Bio-Sciences Ab Method for controlling culture parameters in a bioreactor
AU2011249140B2 (en) 2010-05-04 2013-10-03 Lanzatech Nz, Inc. Improved fermentation of waste gases
CA2786903C (en) * 2010-07-28 2015-01-20 Lanzatech New Zealand Limited Novel bacteria and methods of use thereof for producing ethanol and acetate
CA2807102C (en) 2010-07-31 2018-08-21 Myriant Corporation Improved fermentation process for the production of organic acids
CA2836686C (en) 2010-10-22 2015-11-17 Lanzatech New Zealand Limited Methods and systems for the production of alcohols and/or acids
AU2011316891B2 (en) 2010-10-22 2013-09-19 Lanzatech Nz, Inc. Methods and systems for the production of hydrocarbon products
EA024474B1 (ru) 2010-10-29 2016-09-30 Ланцатек Нью Зилэнд Лимитед Способ производства углеводородных продуктов
KR101950042B1 (ko) * 2010-12-03 2019-02-19 이네오스 바이오 에스에이 비 co-흡수 조절을 포함하는 발효 방법
US10100338B2 (en) * 2012-05-22 2018-10-16 Ineos Bio S.A. Method of operation of a syngas fermentation process
US10233478B2 (en) 2012-09-19 2019-03-19 Ineos Bio Sa Process for reducing CO2 emissions and increasing alcohol productivity in syngas fermentation
WO2014081848A1 (en) 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification

Also Published As

Publication number Publication date
US20160010116A1 (en) 2016-01-14
CA2954496A1 (en) 2016-01-14
BR112017000449B1 (pt) 2022-10-25
KR102531892B1 (ko) 2023-05-11
TWI673366B (zh) 2019-10-01
TW201920688A (zh) 2019-06-01
WO2016007216A1 (en) 2016-01-14
CN106574276B (zh) 2020-11-06
CA3024631C (en) 2022-03-15
EP3167068B1 (en) 2020-10-28
CA2954496C (en) 2019-01-08
CA3024631A1 (en) 2016-01-14
KR20170028389A (ko) 2017-03-13
EP3167068A4 (en) 2018-03-21
EA033036B1 (ru) 2019-08-30
PT3167068T (pt) 2020-12-21
EP3167068A1 (en) 2017-05-17
US20170175064A1 (en) 2017-06-22
TWI649426B (zh) 2019-02-01
JP2019193636A (ja) 2019-11-07
US9617566B2 (en) 2017-04-11
TW201625801A (zh) 2016-07-16
JP6955531B2 (ja) 2021-10-27
US11753612B2 (en) 2023-09-12
PL3167068T3 (pl) 2021-04-19
BR112017000449A2 (pt) 2017-11-07
EA201790136A1 (ru) 2017-05-31
JP2017521077A (ja) 2017-08-03
EP3766983A1 (en) 2021-01-20
ES2841337T3 (es) 2021-07-08
CN106574276A (zh) 2017-04-19

Similar Documents

Publication Publication Date Title
JP6599427B2 (ja) バイオリアクタプロセスの制御
KR102807961B1 (ko) 일산화탄소 및 이산화탄소 생물 전환 방법
CN102471783A (zh) 醇生产方法
JP6662868B2 (ja) 複数ステージバイオリアクタープロセス
JP2026012200A (ja) 生物変換のためのプロセス制御

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180507

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180507

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20180507

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20180827

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180829

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180918

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181218

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190529

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20190711

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190903

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20191002

R150 Certificate of patent or registration of utility model

Ref document number: 6599427

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250