KR102497242B1 - 당뇨병, 고혈압 및 고콜레스테롤혈증을 치료하기 위한 조성물 및 방법 - Google Patents
당뇨병, 고혈압 및 고콜레스테롤혈증을 치료하기 위한 조성물 및 방법 Download PDFInfo
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- KR102497242B1 KR102497242B1 KR1020197015784A KR20197015784A KR102497242B1 KR 102497242 B1 KR102497242 B1 KR 102497242B1 KR 1020197015784 A KR1020197015784 A KR 1020197015784A KR 20197015784 A KR20197015784 A KR 20197015784A KR 102497242 B1 KR102497242 B1 KR 102497242B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Marine Sciences & Fisheries (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662421332P | 2016-11-13 | 2016-11-13 | |
| US62/421,332 | 2016-11-13 | ||
| PCT/US2017/061343 WO2018089909A1 (en) | 2016-11-13 | 2017-11-13 | Compositions and methods for treating diabetes, hypertension and hypercholesterolemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190084070A KR20190084070A (ko) | 2019-07-15 |
| KR102497242B1 true KR102497242B1 (ko) | 2023-02-09 |
Family
ID=62107069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197015784A Active KR102497242B1 (ko) | 2016-11-13 | 2017-11-13 | 당뇨병, 고혈압 및 고콜레스테롤혈증을 치료하기 위한 조성물 및 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10548941B2 (enExample) |
| EP (1) | EP3538124A4 (enExample) |
| JP (3) | JP2020502056A (enExample) |
| KR (1) | KR102497242B1 (enExample) |
| CN (1) | CN110087666B (enExample) |
| AU (2) | AU2017357052B2 (enExample) |
| BR (1) | BR112019009511A2 (enExample) |
| MX (1) | MX2019005466A (enExample) |
| WO (1) | WO2018089909A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110087666B (zh) * | 2016-11-13 | 2024-04-30 | 想象制药公司 | 用于治疗糖尿病、高血压和高胆固醇血症的组合物和方法 |
| JP2021510157A (ja) * | 2018-01-09 | 2021-04-15 | イマジン ファーマ、エルエルシー | 内皮細胞機能障害を調節するためのrps2ペプチドの使用 |
| WO2020005721A1 (en) * | 2018-06-25 | 2020-01-02 | Imagine Pharma, Llc | Compositions and methods for propagating insulin-producing islet cells and therapeutic uses thereof |
| CN110974943A (zh) * | 2019-12-09 | 2020-04-10 | 广东药科大学 | 一种口服胰岛素药物制剂及其制备方法 |
| JP2023552515A (ja) * | 2020-12-08 | 2023-12-18 | イマジン ファーマ、エルエルシー | 創傷を治療するための組成物および方法 |
| WO2023049079A2 (en) * | 2021-09-22 | 2023-03-30 | Imagine Pharma Llc | Compositions and methods for propogating insulin and glucagon secreting cells from type 1 diabetic pancreatic tissue and therapeutic uses thereof |
| CA3235948A1 (en) * | 2021-12-11 | 2023-06-15 | Ngoc THAI | Compositions and methods for oral administration |
| WO2025207834A1 (en) * | 2024-03-28 | 2025-10-02 | Imagine Pharma Llc | Dietary supplements, compositions, and uses thereof for increasing telomerase activity and extending telomere length |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004537274A (ja) | 2001-02-15 | 2004-12-16 | コンドロジェネシス ピーティーワイ リミテッド | 軟骨形成におけるマトリックス遺伝子発現 |
| US20160120999A1 (en) | 2014-10-31 | 2016-05-05 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| WO2017109706A1 (en) | 2015-12-22 | 2017-06-29 | Novartis Ag | Methods of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4025395B2 (ja) * | 1997-04-09 | 2007-12-19 | 花王株式会社 | 新規ペクチン酸リアーゼ |
| US20020042062A1 (en) * | 1999-09-24 | 2002-04-11 | Mark Stearns | Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US20050118151A1 (en) * | 2001-05-29 | 2005-06-02 | Syddansk Universitet | Proteins in diabetes proteome anlysis |
| US20040014040A1 (en) * | 2001-07-10 | 2004-01-22 | Donna Mendrick | Cardiotoxin molecular toxicology modeling |
| EP2275120A3 (en) * | 2002-04-02 | 2011-06-08 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
| AU2004251654A1 (en) * | 2003-06-02 | 2005-01-06 | Icoria, Inc. | Use of genes differentially expressed during aging of liver for treatment and diagnosis |
| JP2005245202A (ja) * | 2004-03-01 | 2005-09-15 | Japan Science & Technology Agency | ヒトTFIIEαの新規な亜鉛結合ドメインの構造的特徴および機能 |
| US20090048199A1 (en) * | 2007-03-09 | 2009-02-19 | Hiberna Corporation | Hibernation-Related Genes and Proteins, Activators and Inhibitors Thereof and Methods of Use |
| US9221886B2 (en) * | 2009-04-28 | 2015-12-29 | President And Fellows Of Harvard College | Supercharged proteins for cell penetration |
| WO2012054739A2 (en) * | 2010-10-21 | 2012-04-26 | New York University | Structure-guided identification of binding interactions of human laminin receptor precursor with laminin and identification of compounds that affect binding |
| CA2817851A1 (en) * | 2010-11-12 | 2012-05-18 | The Johns Hopkins University | Albumin-bound protein/peptide complex as a biomarker for disease |
| ES3039965T3 (en) | 2011-03-01 | 2025-10-28 | NuCana plc | Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine for use in the treatment of cancer |
| EP3048904A2 (en) * | 2013-09-25 | 2016-08-03 | Pronutria Biosciences, Inc. | Compositions and formulations for treatment of gastrointestinal tract malabsorption diseases and inflammatory conditions and methods of production and use thereof |
| CN110087666B (zh) | 2016-11-13 | 2024-04-30 | 想象制药公司 | 用于治疗糖尿病、高血压和高胆固醇血症的组合物和方法 |
| JP2021510157A (ja) * | 2018-01-09 | 2021-04-15 | イマジン ファーマ、エルエルシー | 内皮細胞機能障害を調節するためのrps2ペプチドの使用 |
-
2017
- 2017-11-13 CN CN201780069543.0A patent/CN110087666B/zh active Active
- 2017-11-13 US US15/811,060 patent/US10548941B2/en active Active
- 2017-11-13 KR KR1020197015784A patent/KR102497242B1/ko active Active
- 2017-11-13 JP JP2019524445A patent/JP2020502056A/ja active Pending
- 2017-11-13 BR BR112019009511-0A patent/BR112019009511A2/pt active Search and Examination
- 2017-11-13 WO PCT/US2017/061343 patent/WO2018089909A1/en not_active Ceased
- 2017-11-13 EP EP17868911.3A patent/EP3538124A4/en active Pending
- 2017-11-13 AU AU2017357052A patent/AU2017357052B2/en active Active
- 2017-11-13 MX MX2019005466A patent/MX2019005466A/es unknown
-
2019
- 2019-06-28 US US16/455,878 patent/US10751384B2/en active Active
-
2022
- 2022-05-31 AU AU2022203741A patent/AU2022203741B2/en active Active
-
2023
- 2023-02-07 JP JP2023016485A patent/JP7711967B2/ja active Active
-
2025
- 2025-07-03 JP JP2025113059A patent/JP2025163025A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004537274A (ja) | 2001-02-15 | 2004-12-16 | コンドロジェネシス ピーティーワイ リミテッド | 軟骨形成におけるマトリックス遺伝子発現 |
| US20160120999A1 (en) | 2014-10-31 | 2016-05-05 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| WO2017109706A1 (en) | 2015-12-22 | 2017-06-29 | Novartis Ag | Methods of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15) |
Non-Patent Citations (1)
| Title |
|---|
| GenBank: BAC16801.1, ribosomal protein S2 [Homo sapiens] (2002. 9.28.)* |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110087666A (zh) | 2019-08-02 |
| JP2023071670A (ja) | 2023-05-23 |
| EP3538124A4 (en) | 2020-07-22 |
| AU2017357052B2 (en) | 2022-03-24 |
| EP3538124A1 (en) | 2019-09-18 |
| JP2020502056A (ja) | 2020-01-23 |
| CN110087666B (zh) | 2024-04-30 |
| US20180133280A1 (en) | 2018-05-17 |
| AU2017357052A1 (en) | 2019-05-02 |
| KR20190084070A (ko) | 2019-07-15 |
| JP2025163025A (ja) | 2025-10-28 |
| JP7711967B2 (ja) | 2025-07-23 |
| AU2022203741A1 (en) | 2022-06-23 |
| US10548941B2 (en) | 2020-02-04 |
| US20200222499A1 (en) | 2020-07-16 |
| CA3041362A1 (en) | 2018-05-17 |
| AU2022203741B2 (en) | 2024-02-15 |
| BR112019009511A2 (pt) | 2019-07-30 |
| WO2018089909A1 (en) | 2018-05-17 |
| MX2019005466A (es) | 2019-10-02 |
| US10751384B2 (en) | 2020-08-25 |
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