KR102493376B1 - 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법 - Google Patents

청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법 Download PDF

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KR102493376B1
KR102493376B1 KR1020177008968A KR20177008968A KR102493376B1 KR 102493376 B1 KR102493376 B1 KR 102493376B1 KR 1020177008968 A KR1020177008968 A KR 1020177008968A KR 20177008968 A KR20177008968 A KR 20177008968A KR 102493376 B1 KR102493376 B1 KR 102493376B1
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KR20170055497A (ko
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제프리 엠. 카프
로버트 에스. 랑거
시아오레이 인
니틴 조쉬
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더 브리검 앤드 우먼즈 하스피털, 인크.
메사추세츠 인스티튜트 오브 테크놀로지
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KR1020177008968A 2014-09-03 2015-09-03 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법 Active KR102493376B1 (ko)

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KR1020237002815A KR20230019500A (ko) 2014-09-03 2015-09-03 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462045506P 2014-09-03 2014-09-03
US62/045,506 2014-09-03
US201462051003P 2014-09-16 2014-09-16
US62/051,003 2014-09-16
PCT/US2015/048442 WO2016037016A1 (en) 2014-09-03 2015-09-03 Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss

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KR1020237002815A Division KR20230019500A (ko) 2014-09-03 2015-09-03 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법

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KR20170055497A KR20170055497A (ko) 2017-05-19
KR102493376B1 true KR102493376B1 (ko) 2023-01-27

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KR1020237002815A Ceased KR20230019500A (ko) 2014-09-03 2015-09-03 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법

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US (3) US10568883B2 (enExample)
EP (1) EP3189134A1 (enExample)
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KR (2) KR102493376B1 (enExample)
CN (1) CN107073042A (enExample)
AU (1) AU2015311816B2 (enExample)
CA (1) CA2959404A1 (enExample)
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JP2010509919A (ja) 2006-11-15 2010-04-02 マサチューセッツ・アイ・アンド・イア・インファーマリー 内耳細胞の生成
CA3184040A1 (en) 2013-03-14 2014-10-02 The Brigham And Women's Hospital, Inc. Compositions and methods for epithelial stem cell expansion comprising a wnt agonist and a histone deacetylase inhibitor
WO2016022776A2 (en) 2014-08-06 2016-02-11 Massachusetts Eye And Ear Infirmary Increasing atoh1 life to drive sensorineural hair cell differentiantion
WO2016037016A1 (en) 2014-09-03 2016-03-10 The Brigham And Women's Hospital, Inc. Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss
WO2017096233A1 (en) 2015-12-04 2017-06-08 Massachusetts Eye And Ear Infirmary Treatment of hearing loss by inhibition of casein kinase 1
AU2017205194A1 (en) 2016-01-08 2018-07-19 Massachusetts Institute Of Technology Production of differentiated enteroendocrine cells and insulin producing cells
AU2017212655B2 (en) * 2016-01-29 2024-01-18 Decibel Therapeutics, Inc. Expansion and differentiation of inner ear supporting cells and methods of use thereof
US20190060371A1 (en) * 2016-03-02 2019-02-28 Frequency Therapeutics, Inc. Methods for controlled proliferation of vestibular stem cells / generating inner ear hair cells using wnt and tgfbeta-inhibition
US11260130B2 (en) 2016-03-02 2022-03-01 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV
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US20190247395A9 (en) 2019-08-15
CA2959404A1 (en) 2016-03-10
IL250652A0 (en) 2017-04-30

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