KR102435609B1 - 생물학적 표본의 자동 제조를 위한 시스템 및 방법 - Google Patents
생물학적 표본의 자동 제조를 위한 시스템 및 방법 Download PDFInfo
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- KR102435609B1 KR102435609B1 KR1020217012965A KR20217012965A KR102435609B1 KR 102435609 B1 KR102435609 B1 KR 102435609B1 KR 1020217012965 A KR1020217012965 A KR 1020217012965A KR 20217012965 A KR20217012965 A KR 20217012965A KR 102435609 B1 KR102435609 B1 KR 102435609B1
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020227028531A KR102643765B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201715454819A | 2017-03-09 | 2017-03-09 | |
| US15/454,819 | 2017-03-09 | ||
| KR1020197025192A KR102248971B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| PCT/US2018/021879 WO2018165630A1 (en) | 2017-03-09 | 2018-03-09 | Systems and methods for automated preparation of biological specimens |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197025192A Division KR102248971B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227028531A Division KR102643765B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20210052586A KR20210052586A (ko) | 2021-05-10 |
| KR102435609B1 true KR102435609B1 (ko) | 2022-08-23 |
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| KR1020227040071A Active KR102653551B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020227040068A Active KR102688513B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020197025192A Active KR102248971B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020227028531A Active KR102643765B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020227040071A Active KR102653551B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020227040068A Active KR102688513B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020197025192A Active KR102248971B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
| KR1020227028531A Active KR102643765B1 (ko) | 2017-03-09 | 2018-03-09 | 생물학적 표본의 자동 제조를 위한 시스템 및 방법 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US10900875B2 (enExample) |
| EP (1) | EP3497428B1 (enExample) |
| JP (5) | JP6934061B2 (enExample) |
| KR (5) | KR102435609B1 (enExample) |
| CN (2) | CN115235841B (enExample) |
| AU (5) | AU2018230514B2 (enExample) |
| BR (1) | BR112019015803B1 (enExample) |
| CA (1) | CA3053184C (enExample) |
| IL (2) | IL282867B (enExample) |
| SG (1) | SG11201906814YA (enExample) |
| TW (2) | TWI792862B (enExample) |
| WO (1) | WO2018165630A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD246260S (en) * | 1976-02-09 | 1977-11-01 | Lynne Forrester | Hair color applicator |
| WO2019175371A1 (en) * | 2018-03-16 | 2019-09-19 | Inveox Gmbh | Sample processing system and method for automatically processing histological samples |
| USD883515S1 (en) * | 2018-07-11 | 2020-05-05 | Hologic, Inc. | Tube printer |
| USD874017S1 (en) * | 2018-11-02 | 2020-01-28 | Hologic, Inc | Slide imaging system |
| USD921218S1 (en) | 2019-03-29 | 2021-06-01 | Gen-Probe Incorporated | Pipette tip holder chain link |
| EP3948303B1 (en) | 2019-03-29 | 2025-12-24 | Gen-Probe Incorporated | Disposable pipette tip management |
| DE102019119500A1 (de) * | 2019-07-18 | 2021-01-21 | Leica Biosystems Nussloch Gmbh | Drucker zum Bedrucken von Histologielabor-Verbrauchsartikeln |
| US11607200B2 (en) * | 2019-08-13 | 2023-03-21 | GE Precision Healthcare LLC | Methods and system for camera-aided ultrasound scan setup and control |
| EP4051622A4 (en) | 2019-10-29 | 2023-12-13 | Beckman Coulter, Inc. | SAMPLE TUBE CUTTER |
| CN113495085B (zh) * | 2020-04-03 | 2023-07-07 | 深圳市帝迈生物技术有限公司 | Poct血细胞分析仪及阻抗检测池的液体流动的驱动装置 |
| US11914131B1 (en) * | 2020-08-16 | 2024-02-27 | Gregory Dimitrenko | Optical testing system for detecting infectious disease, testing device, specimen collector and related methods |
| KR102576041B1 (ko) * | 2021-02-09 | 2023-09-07 | (주)유아이엠디 | 슬라이드 표본의 고배율 이미지 획득방법 |
| CN115970782A (zh) * | 2021-10-14 | 2023-04-18 | 博讯生物科技股份有限公司 | 吸液器的吸管尖连接装置及连接方法 |
| US12360133B2 (en) * | 2021-11-01 | 2025-07-15 | Drsignal Biotechnology Co., Ltd. | Pipette-tip connecting device and method thereof |
| EP4075147B1 (en) * | 2021-11-02 | 2025-01-15 | Drsignal Biotechnology Co., Ltd | Pipette-tip connecting device and method thereof |
| CN114354308B (zh) * | 2021-12-27 | 2024-03-19 | 厦门大学 | 一种全自动制片染色阅片一体机 |
| CN114394310A (zh) * | 2022-01-21 | 2022-04-26 | 中南大学湘雅医院 | 一种分子生物学实验样品储存装置 |
| WO2023201066A1 (en) * | 2022-04-15 | 2023-10-19 | Polybiomics, Inc. | Polybiosensing and imaging platform system, method and device |
| TWI828389B (zh) * | 2022-10-26 | 2024-01-01 | 信任生醫股份有限公司 | 樣本處理模組及包含該樣本處理模組的生物樣本處理設備 |
| CN115926957A (zh) * | 2022-11-01 | 2023-04-07 | 苏州莱博睿思生物科技有限公司 | 一种采集器、细胞分选设备及细胞采集方法 |
| TWI883681B (zh) * | 2023-12-01 | 2025-05-11 | 達易特基因科技股份有限公司 | 生物晶片定量定性分析自動化判讀系統 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006075201A1 (en) | 2004-09-08 | 2006-07-20 | Pfizer Products Inc. | Automated system for handling and weighing analytic quantities of particulate substances |
| US20110088517A1 (en) | 2008-05-22 | 2011-04-21 | Hitachi High-Technologies Corporation | System for pretreating sample |
| JP2014526687A (ja) | 2011-09-09 | 2014-10-06 | ジェン−プローブ・インコーポレーテッド | 自動試料操作器具、システム、プロセス、及び方法 |
Family Cites Families (79)
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|---|---|---|---|---|
| JPS5349479U (enExample) * | 1976-09-30 | 1978-04-26 | ||
| JPS6365370A (ja) * | 1986-09-05 | 1988-03-23 | Nippon Tectron Co Ltd | サンプルピペツト装置 |
| US5166889A (en) * | 1989-01-10 | 1992-11-24 | Medical Robotics, Inc. | Robotic liquid sampling system |
| US5143627A (en) * | 1990-07-09 | 1992-09-01 | Cytyc Corporation | Method and apparatus for preparing cells for examination |
| US5282978A (en) | 1990-07-09 | 1994-02-01 | Cytyc Corporation | Specimen processor method and apparatus |
| US5269918A (en) | 1990-07-09 | 1993-12-14 | Cytyc Corporation | Clinical cartridge apparatus |
| US5240606A (en) | 1990-07-09 | 1993-08-31 | Cytyc Corporation | Apparatus for preparing cells for examination |
| WO1998001760A2 (en) * | 1996-07-05 | 1998-01-15 | Beckman Coulter, Inc. | Automated sample processing system |
| DE29814119U1 (de) * | 1998-08-06 | 1999-02-18 | Brauner, Rainer, 97072 Würzburg | UHV-kompatibler Probenhalter |
| US6572824B1 (en) | 1998-09-18 | 2003-06-03 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| US6562299B1 (en) | 1998-09-18 | 2003-05-13 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| DE19917646B4 (de) * | 1999-04-19 | 2013-06-20 | Siemens Healthcare Diagnostics Products Gmbh | Verschlußvorrichtung für Reagenzbehälter |
| US6665060B1 (en) | 1999-10-29 | 2003-12-16 | Cytyc Corporation | Cytological imaging system and method |
| US7006674B1 (en) | 1999-10-29 | 2006-02-28 | Cytyc Corporation | Apparatus and methods for verifying the location of areas of interest within a sample in an imaging system |
| FR2810407B1 (fr) * | 2000-06-16 | 2002-08-02 | Philippe Escal | Appareil pour l'analyse d'echantillons |
| WO2002029419A2 (de) * | 2000-10-06 | 2002-04-11 | Chemspeed Ltd. | Vorrichtung mit einem werkzeughalter und einem abnehmbar befestigbaren werkzeug |
| US7771662B2 (en) | 2001-10-19 | 2010-08-10 | Hologic, Inc | Vial system and method for processing liquid-based specimens |
| AU2006235787A1 (en) * | 2001-10-19 | 2006-11-23 | Monogen, Inc | Automated system and method for processing multiple liquid-based specimens |
| JP3694490B2 (ja) * | 2002-03-29 | 2005-09-14 | アロカ株式会社 | 検体前処理システム |
| US7648678B2 (en) * | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| JP3972012B2 (ja) * | 2003-03-19 | 2007-09-05 | 株式会社日立ハイテクノロジーズ | 試料分注機構及びそれを備えた自動分析装置 |
| ES2220227B1 (es) * | 2003-05-30 | 2006-02-16 | INSTITUTO NACIONAL DE TECNICA AEROESPACIAL "ESTEBAN TERRADAS" | Metodo y aparato para la deteccion de sustancias o analitos a partir del analisis de una o varias muestras. |
| KR101106358B1 (ko) | 2003-06-12 | 2012-01-18 | 사이틱 코포레이션 | 관심필드의 다수의 물질을 조직화하기 위한 시스템 |
| EP1508809B1 (en) * | 2003-08-20 | 2007-02-28 | Sysmex Corporation | Sample analyzer and nucleic acid detector |
| US7083106B2 (en) | 2003-09-05 | 2006-08-01 | Cytyc Corporation | Locally storing biological specimen data to a slide |
| US20050100483A1 (en) | 2003-11-12 | 2005-05-12 | Cytyc Corporation | Specimen filter container having data storage |
| US8043562B2 (en) * | 2003-12-08 | 2011-10-25 | Ortho-Clinical Diagnostics, Inc. | Analyzer having removable holders or a centrifuge |
| JP4221349B2 (ja) * | 2004-09-17 | 2009-02-12 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| JP3980031B2 (ja) * | 2005-02-09 | 2007-09-19 | 株式会社日立製作所 | 自動分析装置 |
| US7556777B2 (en) | 2005-03-08 | 2009-07-07 | Cytyc Corporation | Specimen vial cap handler and slide labeler |
| US7998751B2 (en) * | 2005-04-26 | 2011-08-16 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for aspirating and dispensing small liquid samples in an automated clinical analyzer |
| US7587078B2 (en) | 2005-05-02 | 2009-09-08 | Cytyc Corporation | Automated image analysis |
| US7686771B2 (en) | 2005-12-12 | 2010-03-30 | Cytyc Corporation | Method and apparatus for obtaining aliquot from liquid-based cytological sample |
| US20070148041A1 (en) | 2005-12-22 | 2007-06-28 | Cytyc Corporation | Systems methods and kits for preparing specimen slides |
| CA2635268C (en) * | 2006-01-18 | 2021-02-16 | Argos Therapeutics, Inc. | Systems and methods for processing samples in a closed container, and related devices |
| KR100887590B1 (ko) * | 2006-03-21 | 2009-03-11 | 김일희 | 생물시료 부착장치 |
| US9103806B2 (en) * | 2006-04-24 | 2015-08-11 | Protedyne Corporation | Robotic system with autonomously operable tools |
| US20080020467A1 (en) * | 2006-07-20 | 2008-01-24 | Lawrence Barnes | Fluid metering in a metering zone |
| US7674434B2 (en) | 2006-11-27 | 2010-03-09 | Cytyc Corporation | Vials and apparatus for obtaining an aliquot of a sample |
| WO2008067844A1 (en) * | 2006-12-04 | 2008-06-12 | Inpeco Ip Ltd. | Apparatus for removing caps from tubular containers |
| US8119399B2 (en) | 2006-12-13 | 2012-02-21 | Cytyc Corporation | Method and system for collecting cells of a biological specimen |
| US20080145887A1 (en) | 2006-12-19 | 2008-06-19 | Cytyc Corporation | Cytological filter with data storage |
| US8354078B2 (en) * | 2007-03-30 | 2013-01-15 | Sysmex Corporation | Liquid aspirating tube, liquid dispensing apparatus and liquid dispensing method |
| WO2008123882A1 (en) * | 2007-04-06 | 2008-10-16 | Richard Obiso | Sample preparation system for processing of clinical specimens |
| JP4959450B2 (ja) * | 2007-07-10 | 2012-06-20 | 株式会社日立ハイテクノロジーズ | 化学分析装置 |
| ES2435666T3 (es) * | 2007-07-10 | 2013-12-20 | Ventana Medical Systems, Inc. | Aparato y método para el tratamiento de muestras biológicas |
| EP2031407B1 (en) * | 2007-08-29 | 2012-06-06 | F. Hoffmann-La Roche AG | Decapping system |
| US8119363B2 (en) | 2008-05-02 | 2012-02-21 | Cellsolutions, Llc | Cell sample preparation method and apparatus |
| US8137642B2 (en) | 2008-06-13 | 2012-03-20 | Cytyc Corporation | Method and apparatus for calibrating filters during specimen collection |
| JP5431755B2 (ja) * | 2008-10-31 | 2014-03-05 | シスメックス株式会社 | 検体分析装置および検体分析方法 |
| AU2010248902B2 (en) * | 2009-05-15 | 2015-02-26 | Biomerieux, Inc. | Automated microbial detection apparatus |
| WO2011002779A2 (en) * | 2009-06-30 | 2011-01-06 | Ventana Medical Systems, Inc. | Methods and apparatuses for applying and removing fluids for processing biological samples |
| US10288632B2 (en) * | 2009-09-21 | 2019-05-14 | Pocared Diagnostics Ltd. | System for conducting the identification of bacteria in biological samples |
| JP5346265B2 (ja) * | 2009-09-30 | 2013-11-20 | シスメックス株式会社 | 検体分析装置および検体分析方法 |
| PL2388561T3 (pl) | 2010-05-20 | 2016-05-31 | Mettler Toledo Gmbh | Urządzenie laboratoryjne do przygotowywania próbek |
| US20140335554A1 (en) * | 2010-12-01 | 2014-11-13 | President And Fellows Of Harvard College | Apparatus and methods for aliquotting frozen samples |
| EP2538225A1 (en) * | 2011-06-20 | 2012-12-26 | F. Hoffmann-La Roche AG | System for processing closed sample tubes |
| EP2728362B1 (en) | 2011-06-30 | 2016-03-02 | Hitachi High-Technologies Corporation | Automatic analysis system |
| JP5709678B2 (ja) * | 2011-07-14 | 2015-04-30 | パナソニックヘルスケアホールディングス株式会社 | 分注装置 |
| CN103733072B (zh) | 2011-08-22 | 2016-10-19 | 株式会社日立高新技术 | 栓开闭装置及试样处理装置 |
| GB2495934A (en) * | 2011-10-25 | 2013-05-01 | Tap Biosystems Phc Ltd | Bioreactor outlet air conditioning systems and associated methods |
| FI20116059A7 (fi) * | 2011-10-28 | 2013-04-29 | Thermo Fisher Scientific Oy | Reagenssipullo, järjestelmä, menetelmä ja laite suljinkorkkien ja vastaavien käsittelemiseksi |
| JP6082018B2 (ja) | 2011-11-07 | 2017-02-15 | ベックマン コールター， インコーポレイテッド | サンプルを処理するためのシステムおよび方法 |
| DE102011055899B4 (de) * | 2011-11-30 | 2013-11-21 | Andreas Hettich Gmbh & Co. Kg | Verfahren und eine Vorrichtung zum Handhaben von Probenbehältern |
| US9199755B1 (en) * | 2012-02-11 | 2015-12-01 | Joseph Cohen | Apparatus and methods for handling tubes or vials |
| DE102012208707A1 (de) * | 2012-05-24 | 2013-12-12 | Hamilton Bonaduz Ag | Probenverarbeitungssystem zum Verarbeiten von biologischen Proben |
| JP6215336B2 (ja) * | 2012-11-01 | 2017-10-18 | ライカ・バイオシステムズ・メルボルン・プロプライエタリー・リミテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｍｅｌｂｏｕｒｎｅ Ｐｔｙ Ｌｔｄ | スライド輸送システム |
| AU2013202805B2 (en) | 2013-03-14 | 2015-07-16 | Gen-Probe Incorporated | System and method for extending the capabilities of a diagnostic analyzer |
| EP2792598B1 (de) * | 2013-04-19 | 2016-05-18 | Mettler-Toledo GmbH | Probenvorbereiter mit Drehgreifer |
| EP3096149A4 (en) * | 2014-01-16 | 2017-10-18 | Universal Bio Research Co., Ltd. | Soft stopper-penetrating pipetting device, and soft stopper-penetrating pipetting method |
| CA3047441C (en) | 2014-10-21 | 2022-03-22 | Gen-Probe Incorporated | Method and apparatus for printing on an object having a curved surface |
| JP6535487B2 (ja) * | 2015-03-18 | 2019-06-26 | あおい精機株式会社 | 閉栓装置、閉栓ユニット及び閉栓方法 |
| DK3304032T3 (da) * | 2015-05-28 | 2024-05-13 | Bd Kiestra Bv | Automatiseret fremgangsmåde og system til at opnå og fremstille mikroorganismeprøver til både identifikations- og antibiotisk susceptibilitetstest |
| US10094847B2 (en) | 2015-07-31 | 2018-10-09 | Gen-Probe Incorporated | Automated sample processing instruments, systems, processes, and methods |
| JP6922907B2 (ja) * | 2016-06-21 | 2021-08-18 | コニカミノルタ株式会社 | 反応方法、ならびにこれを行う反応システムおよび反応装置 |
| CN110537099A (zh) * | 2017-04-20 | 2019-12-03 | 生物流体有限公司 | 用于从液体样本中分离生物标记物的流体密封流量系统 |
| EP3677916B1 (en) * | 2018-01-26 | 2023-07-12 | Hitachi High-Tech Corporation | Automated analyzer |
| EP3620772B1 (en) * | 2018-09-06 | 2021-10-13 | Milestone S.r.l. | System and method for filling a closed container with a fixative solution |
| EP3693745B1 (en) * | 2019-02-07 | 2023-05-17 | Sartorius Biohit Liquid Handling Oy | Tip removal in automated pipette module |
-
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006075201A1 (en) | 2004-09-08 | 2006-07-20 | Pfizer Products Inc. | Automated system for handling and weighing analytic quantities of particulate substances |
| US20110088517A1 (en) | 2008-05-22 | 2011-04-21 | Hitachi High-Technologies Corporation | System for pretreating sample |
| JP2014526687A (ja) | 2011-09-09 | 2014-10-06 | ジェン−プローブ・インコーポレーテッド | 自動試料操作器具、システム、プロセス、及び方法 |
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