KR102434817B1 - 15-hepe를 포함하는 조성물 및 그의 사용 방법 - Google Patents

15-hepe를 포함하는 조성물 및 그의 사용 방법 Download PDF

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Publication number
KR102434817B1
KR102434817B1 KR1020217020740A KR20217020740A KR102434817B1 KR 102434817 B1 KR102434817 B1 KR 102434817B1 KR 1020217020740 A KR1020217020740 A KR 1020217020740A KR 20217020740 A KR20217020740 A KR 20217020740A KR 102434817 B1 KR102434817 B1 KR 102434817B1
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South Korea
Prior art keywords
ohepa
pharmaceutical composition
hepe
disease
present
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English (en)
Korean (ko)
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KR20210088733A (ko
Inventor
조나단 로우
케빈 더피
존 클라이맥스
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애피뮨 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
KR1020217020740A 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법 Active KR102434817B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227028323A KR102514913B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1301626.6A GB201301626D0 (en) 2013-01-30 2013-01-30 Composition comprising 15-OHEPA and methods of using the same
GB1301626.6 2013-01-30
KR1020157020952A KR102274963B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
PCT/EP2014/051455 WO2014118097A1 (en) 2013-01-30 2014-01-24 Compositions comprising 15-ohepa and methods of using the same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020157020952A Division KR102274963B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227028323A Division KR102514913B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법

Publications (2)

Publication Number Publication Date
KR20210088733A KR20210088733A (ko) 2021-07-14
KR102434817B1 true KR102434817B1 (ko) 2022-08-19

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ID=47891001

Family Applications (6)

Application Number Title Priority Date Filing Date
KR1020217020740A Active KR102434817B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020237009963A Ceased KR20230047201A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020247001131A Ceased KR20240011872A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020257022099A Pending KR20250105691A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020227028323A Active KR102514913B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020157020952A Active KR102274963B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법

Family Applications After (5)

Application Number Title Priority Date Filing Date
KR1020237009963A Ceased KR20230047201A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020247001131A Ceased KR20240011872A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020257022099A Pending KR20250105691A (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020227028323A Active KR102514913B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법
KR1020157020952A Active KR102274963B1 (ko) 2013-01-30 2014-01-24 15-hepe를 포함하는 조성물 및 그의 사용 방법

Country Status (27)

Country Link
US (6) US20150224076A1 (enExample)
EP (2) EP2762143B1 (enExample)
JP (2) JP6363104B2 (enExample)
KR (6) KR102434817B1 (enExample)
CN (2) CN105120872B (enExample)
AU (2) AU2014211628B2 (enExample)
BR (1) BR112015018270A2 (enExample)
CA (1) CA2897343C (enExample)
CY (1) CY1117209T1 (enExample)
DK (1) DK2762143T3 (enExample)
ES (2) ES2564025T3 (enExample)
GB (1) GB201301626D0 (enExample)
HR (1) HRP20160203T1 (enExample)
HU (1) HUE026901T2 (enExample)
IL (3) IL239893A (enExample)
MX (2) MX364646B (enExample)
NZ (1) NZ709803A (enExample)
PH (1) PH12015501582B1 (enExample)
PL (1) PL2762143T3 (enExample)
PT (1) PT2762143E (enExample)
RS (1) RS54584B1 (enExample)
RU (2) RU2671208C2 (enExample)
SG (2) SG11201505457PA (enExample)
SI (1) SI2762143T1 (enExample)
SM (1) SMT201600069B (enExample)
WO (1) WO2014118097A1 (enExample)
ZA (2) ZA201505018B (enExample)

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Also Published As

Publication number Publication date
AU2014211628B2 (en) 2018-04-19
KR20230047201A (ko) 2023-04-06
ZA201605125B (en) 2018-06-27
IL265876A (en) 2019-06-30
CN105120872A (zh) 2015-12-02
US10813903B2 (en) 2020-10-27
EP3058943A1 (en) 2016-08-24
JP2018172409A (ja) 2018-11-08
EP2762143A1 (en) 2014-08-06
MX364646B (es) 2019-05-03
HUE026901T2 (en) 2016-07-28
EP3058943B1 (en) 2019-09-25
PT2762143E (pt) 2016-03-28
MX2015009803A (es) 2015-10-29
KR20150112995A (ko) 2015-10-07
BR112015018270A2 (pt) 2017-07-18
RU2015136849A (ru) 2017-03-06
US20150224076A1 (en) 2015-08-13
KR102514913B1 (ko) 2023-03-27
NZ709803A (en) 2020-05-29
SMT201600069B (it) 2016-04-29
CA2897343C (en) 2021-03-16
JP6363104B2 (ja) 2018-07-25
US20210244697A1 (en) 2021-08-12
SG11201505457PA (en) 2015-08-28
KR102274963B1 (ko) 2021-07-08
CA2897343A1 (en) 2014-08-07
KR20210088733A (ko) 2021-07-14
ZA201505018B (en) 2017-01-25
IL239893A (en) 2017-04-30
US20220347147A1 (en) 2022-11-03
GB201301626D0 (en) 2013-03-13
IL239893A0 (en) 2015-08-31
US20250186384A1 (en) 2025-06-12
PH12015501582B1 (en) 2019-10-25
RU2018136872A (ru) 2018-11-27
US20200069626A1 (en) 2020-03-05
CN105120872B (zh) 2020-01-10
PH12015501582A1 (en) 2015-10-05
DK2762143T3 (en) 2016-03-07
RS54584B1 (sr) 2016-08-31
JP2016511753A (ja) 2016-04-21
PL2762143T3 (pl) 2016-06-30
MX2019005082A (es) 2019-08-12
ES2759448T3 (es) 2020-05-11
HRP20160203T1 (hr) 2016-03-25
SI2762143T1 (sl) 2016-04-29
IL251639A0 (en) 2017-06-29
EP2762143B1 (en) 2015-12-02
KR20220119524A (ko) 2022-08-29
CY1117209T1 (el) 2017-04-05
CN111214464A (zh) 2020-06-02
KR20240011872A (ko) 2024-01-26
US20210228524A1 (en) 2021-07-29
RU2671208C2 (ru) 2018-10-30
AU2018206685A1 (en) 2018-08-02
HK1200351A1 (en) 2015-08-07
WO2014118097A1 (en) 2014-08-07
KR20250105691A (ko) 2025-07-08
ES2564025T3 (es) 2016-03-17
SG10201806854XA (en) 2018-09-27
AU2014211628A1 (en) 2015-07-30

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