CY1117209T1 - Συνθεσεις περιλαμβανοντας 15-ηερε και μεθοδοι χρησης των ιδιων - Google Patents

Συνθεσεις περιλαμβανοντας 15-ηερε και μεθοδοι χρησης των ιδιων

Info

Publication number
CY1117209T1
CY1117209T1 CY20161100155T CY161100155T CY1117209T1 CY 1117209 T1 CY1117209 T1 CY 1117209T1 CY 20161100155 T CY20161100155 T CY 20161100155T CY 161100155 T CY161100155 T CY 161100155T CY 1117209 T1 CY1117209 T1 CY 1117209T1
Authority
CY
Cyprus
Prior art keywords
methods
owners
days
compositions including
fatty liver
Prior art date
Application number
CY20161100155T
Other languages
Greek (el)
English (en)
Inventor
Jonathan Rowe
Kevin Duffy
John Climax
Original Assignee
Dignity Sciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dignity Sciences Limited filed Critical Dignity Sciences Limited
Publication of CY1117209T1 publication Critical patent/CY1117209T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
CY20161100155T 2013-01-30 2016-02-25 Συνθεσεις περιλαμβανοντας 15-ηερε και μεθοδοι χρησης των ιδιων CY1117209T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1301626.6A GB201301626D0 (en) 2013-01-30 2013-01-30 Composition comprising 15-OHEPA and methods of using the same
EP13176516.6A EP2762143B1 (en) 2013-01-30 2013-07-15 Compositions comprising 15-HEPE and methods of using the same

Publications (1)

Publication Number Publication Date
CY1117209T1 true CY1117209T1 (el) 2017-04-05

Family

ID=47891001

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100155T CY1117209T1 (el) 2013-01-30 2016-02-25 Συνθεσεις περιλαμβανοντας 15-ηερε και μεθοδοι χρησης των ιδιων

Country Status (27)

Country Link
US (6) US20150224076A1 (enExample)
EP (2) EP3058943B1 (enExample)
JP (2) JP6363104B2 (enExample)
KR (6) KR102514913B1 (enExample)
CN (2) CN111214464A (enExample)
AU (2) AU2014211628B2 (enExample)
BR (1) BR112015018270A2 (enExample)
CA (1) CA2897343C (enExample)
CY (1) CY1117209T1 (enExample)
DK (1) DK2762143T3 (enExample)
ES (2) ES2759448T3 (enExample)
GB (1) GB201301626D0 (enExample)
HR (1) HRP20160203T1 (enExample)
HU (1) HUE026901T2 (enExample)
IL (3) IL239893A (enExample)
MX (2) MX364646B (enExample)
NZ (1) NZ709803A (enExample)
PH (1) PH12015501582B1 (enExample)
PL (1) PL2762143T3 (enExample)
PT (1) PT2762143E (enExample)
RS (1) RS54584B1 (enExample)
RU (2) RU2671208C2 (enExample)
SG (2) SG11201505457PA (enExample)
SI (1) SI2762143T1 (enExample)
SM (1) SMT201600069B (enExample)
WO (1) WO2014118097A1 (enExample)
ZA (2) ZA201505018B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
GB201301626D0 (en) 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
ES2727387T3 (es) 2013-11-15 2019-10-15 Ds Biopharma Ltd Sal de lisina de ácido 15-hidroxi-8(Z),11(Z),13(E)-eicosatrienoico
RU2685706C2 (ru) * 2014-01-10 2019-04-23 Эфиммьюн Лимитед Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением
MA41120A (fr) * 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
CN107405324A (zh) * 2015-01-16 2017-11-28 艾菲穆恩有限公司 包含15‑hepe的组合物和其使用方法
AU2016256552B2 (en) 2015-04-28 2021-04-01 Pronova Biopharma Norge As Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis
US10047033B2 (en) * 2015-05-13 2018-08-14 Ds Biopharma Limited Compositions comprising oxo-derivatives of fatty acids and methods of making and using same
CN112245420A (zh) * 2015-07-21 2021-01-22 艾菲穆恩有限公司 用于治疗或预防癌症和神经疾病的包括15-hepe的组合物
AU2016370626B2 (en) 2015-12-18 2020-08-20 Afimmune Limited Compositions comprising 15-HEPE and methods of using the same
IL308604B2 (en) 2017-12-06 2025-08-01 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
CN115215725A (zh) * 2021-04-15 2022-10-21 宋晓瑜 一种制备乙酸薰衣草酯及薰衣草醇的方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05186342A (ja) * 1992-01-10 1993-07-27 Fujirebio Inc 免疫調節作用を併せもつ抗炎症剤
AU673700B2 (en) 1993-01-27 1996-11-21 Scotia Holdings Plc Triglycerides
DE69407949T2 (de) 1993-10-01 1998-05-14 Scherer Corp R P Zusammensetzungen zum verteilen von duftstoffen
US20020055539A1 (en) * 1996-10-02 2002-05-09 Bockow Barry I. Compositions and methods for treating cardiovascular conditions
WO1999058120A1 (en) * 1998-05-08 1999-11-18 Rolf Berge USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS
JP2000191525A (ja) 1998-12-25 2000-07-11 Nof Corp 皮膚外用剤組成物
IL151299A0 (en) 2000-02-16 2003-04-10 Brigham & Womens Hospital Aspirin-triggered lipid mediators
US20040043013A1 (en) 2000-12-28 2004-03-04 Mccleary Edward Larry Metabolic uncoupling therapy
US20020198177A1 (en) 2001-05-30 2002-12-26 Horrobin David Frederick Coenzyme Q and EPA
CN1250230C (zh) * 2001-09-30 2006-04-12 中国药品生物制品检定所 海狗油作为制备治脂肪肝药的应用
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
JP2005179211A (ja) 2003-12-17 2005-07-07 Idemitsu Kosan Co Ltd 皮膚外用剤組成物
WO2005063231A2 (en) 2003-12-31 2005-07-14 Igennus Limited Formulation containing an eicosapentaenoic acid or an ester thereof and a triterpene or esther thereof
WO2005102309A2 (en) 2004-04-26 2005-11-03 Ltb4 Sweden Ab In vivo release of endogenous anti-microbial mediators by leukotriene b4 (ltb4) administration
US20050282781A1 (en) 2004-06-18 2005-12-22 Shibnath Ghosal Compositions of stable bioactive metabolites of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids
AU2005262392A1 (en) 2004-07-01 2006-01-19 Johnson & Johnson Vision Care, Inc. Compositions and methods for treating eye disorders and conditions
EP1973536A2 (en) * 2006-01-05 2008-10-01 Reliant Pharmaceuticals, Inc. Treatment of fatty liver
JP2010500566A (ja) 2006-08-08 2010-01-07 テシス バイオサイエンス, インコーポレイテッド 非アルコール性脂肪肝疾患(nafld)および非アルコール性脂肪性肝炎(nash)のマーカーおよびその使用方法
WO2008126363A1 (ja) * 2007-03-30 2008-10-23 Kowa Company, Ltd. 脂肪肝又は非アルコール性脂肪性肝炎の予防及び/又は治療のための医薬
GB0802116D0 (en) 2008-02-05 2008-03-12 Natural Enviromental Res Counc Treatment
WO2009154230A1 (ja) * 2008-06-17 2009-12-23 持田製薬株式会社 非アルコール性脂肪肝炎の予防/改善・治療薬
EP2415748A4 (en) * 2009-02-20 2013-08-07 Univ Tokyo NEW INFLAMMATORY COMPOUNDS
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
CA2690488C (en) 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
EP2607358A4 (en) * 2010-08-19 2014-01-29 Univ Tokyo NEW OMEGA-3 FATTY ACIDS RECOVERY-RESISTANT METABOLITE
WO2012031125A2 (en) 2010-09-01 2012-03-08 The General Hospital Corporation Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine
US10154977B2 (en) 2011-03-25 2018-12-18 The Brigham And Women's Hospital, Inc. Anti-inflammatory particles
US20120264824A1 (en) 2011-04-15 2012-10-18 Mochida Pharmaceutical Co., Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
RU2014119948A (ru) 2011-10-19 2015-11-27 Дигнити Сайенсиз Лимитед ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ DGLA И/ИЛИ 15-HETrE, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
CA2856715A1 (en) 2011-11-29 2013-06-06 Dignity Sciences Limited Compositions comprising 20-carbon fatty acids and methods of making and using same
CN107050457A (zh) 2012-01-06 2017-08-18 翁特拉制药公司 游离酸形式的ω‑3多不饱和脂肪酸的富含dpa组合物
US20120264705A1 (en) 2012-01-26 2012-10-18 Dignity Sciences Limited Antimicrobial compositions comprising 15-hetre and methods of use thereof
US20130267598A1 (en) 2012-02-23 2013-10-10 Dignity Sciences Limited Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same
AU2013259503B2 (en) * 2012-05-10 2017-03-16 Solutex Na Llc Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
GB201213484D0 (en) * 2012-07-30 2012-09-12 Dignity Sciences Ltd Pharmaceutical compositions comprising 15-OHEPA and methods of using the same
GB201301626D0 (en) * 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
MA41120A (fr) 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
CN112245420A (zh) * 2015-07-21 2021-01-22 艾菲穆恩有限公司 用于治疗或预防癌症和神经疾病的包括15-hepe的组合物
AU2016370626B2 (en) 2015-12-18 2020-08-20 Afimmune Limited Compositions comprising 15-HEPE and methods of using the same

Also Published As

Publication number Publication date
PH12015501582B1 (en) 2019-10-25
RU2018136872A (ru) 2018-11-27
MX364646B (es) 2019-05-03
WO2014118097A1 (en) 2014-08-07
KR20250105691A (ko) 2025-07-08
KR20210088733A (ko) 2021-07-14
KR102274963B1 (ko) 2021-07-08
HRP20160203T1 (hr) 2016-03-25
KR20230047201A (ko) 2023-04-06
CA2897343C (en) 2021-03-16
EP2762143A1 (en) 2014-08-06
CA2897343A1 (en) 2014-08-07
GB201301626D0 (en) 2013-03-13
IL239893A0 (en) 2015-08-31
CN111214464A (zh) 2020-06-02
JP2016511753A (ja) 2016-04-21
ZA201605125B (en) 2018-06-27
HK1200351A1 (en) 2015-08-07
ES2759448T3 (es) 2020-05-11
SG11201505457PA (en) 2015-08-28
RU2015136849A (ru) 2017-03-06
EP3058943A1 (en) 2016-08-24
JP2018172409A (ja) 2018-11-08
EP3058943B1 (en) 2019-09-25
US20200069626A1 (en) 2020-03-05
RS54584B1 (sr) 2016-08-31
IL239893A (en) 2017-04-30
AU2018206685A1 (en) 2018-08-02
SG10201806854XA (en) 2018-09-27
AU2014211628A1 (en) 2015-07-30
KR102514913B1 (ko) 2023-03-27
US10813903B2 (en) 2020-10-27
MX2019005082A (es) 2019-08-12
PT2762143E (pt) 2016-03-28
RU2671208C2 (ru) 2018-10-30
US20250186384A1 (en) 2025-06-12
SMT201600069B (it) 2016-04-29
KR20220119524A (ko) 2022-08-29
SI2762143T1 (sl) 2016-04-29
MX2015009803A (es) 2015-10-29
IL265876A (en) 2019-06-30
DK2762143T3 (en) 2016-03-07
BR112015018270A2 (pt) 2017-07-18
PL2762143T3 (pl) 2016-06-30
US20220347147A1 (en) 2022-11-03
US20150224076A1 (en) 2015-08-13
ZA201505018B (en) 2017-01-25
CN105120872B (zh) 2020-01-10
IL251639A0 (en) 2017-06-29
KR102434817B1 (ko) 2022-08-19
US20210244697A1 (en) 2021-08-12
KR20240011872A (ko) 2024-01-26
US20210228524A1 (en) 2021-07-29
AU2014211628B2 (en) 2018-04-19
PH12015501582A1 (en) 2015-10-05
CN105120872A (zh) 2015-12-02
EP2762143B1 (en) 2015-12-02
ES2564025T3 (es) 2016-03-17
NZ709803A (en) 2020-05-29
KR20150112995A (ko) 2015-10-07
HUE026901T2 (en) 2016-07-28
JP6363104B2 (ja) 2018-07-25

Similar Documents

Publication Publication Date Title
CY1125977T1 (el) Ενωσεiς που αλληλεπιδρουν με τη γλυκανη και μεθοδοι χρησης
MX2019005082A (es) Composiciones que comprenden 15-ohepa y metodos para usar las mismas.
CY1121517T1 (el) Μη φουκοζυλιωμενα αντισωματα enanti-fgfr2iiib
CY1123845T1 (el) Τοπικα φαρμακευτικα σκευασματα για την αγωγη φλεγμονωδων καταστασεων
EA201692301A1 (ru) Производные бороновой кислоты и их терапевтическое применение
MX387817B (es) Uso de acidos grasos de cadena corta en prevencion de cancer.
PH12017501956A1 (en) Compositions of obeticholic acid and methods of use
WO2014197871A3 (en) Antibody-drug conjugates, compositions and methods of use
MX2016002544A (es) Compuestos utiles como inmunomoduladores.
EA201691988A1 (ru) Производные бороновой кислоты и их терапевтическое применение
MX2017001279A (es) Usos y composiciones de la flagelina.
EA201691940A1 (ru) Новые соединения
EA201591004A1 (ru) Производные бороновой кислоты и их терапевтическое применение
JO3155B1 (ar) معدِّل نكهة حلوة
CY1122441T1 (el) Καινοτομες ενωσεις και συζευγματα κρυπτοφυκινης, η παρασκευη τους και η θεραπευτικη χρηση τους
MY186547A (en) 4?-fluoro-2?-methyl substituted nucleoside derivatives
CY1121326T1 (el) Υποκατεστημενη 2,4 διαμινο-κινολινη ως νεοι αντικαρκινικοι παραγοντες
CY1120759T1 (el) Παρασκευη διγλυκοζιτη (s,s)-σεκοϊσολαρικιρεσινολης και διγλυκοζιτη (r,r)-σεκοϊσολαρικιρεσινολης
PL423259A1 (pl) Koniugaty przeciwciało-ureaza dla celów terapeutycznych
MY180844A (en) Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions
MY182134A (en) Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and uses thereof
BR112015023383A2 (pt) compostocomposição farmacêutica; e método de modulação
MX2019002579A (es) Composiciones y metodos de uso de depuradores de gamma-cetoaldehido para tratar, evitar o mejorar la enfermedad del higado graso no alcoholico (nafld), nash, ald o condiciones relacionadas al higado.
EA201591704A1 (ru) Новые устойчивые соли пентадекапептида, способ их получения, их применение в производстве фармацевтических составов и их применение в терапии
PH12017501147A1 (en) Total synthesis of trioxacarcin dc-45-a2 and preparation of trioxacarcin analogs