KR102422492B1 - 카나비제롤 유도체 - Google Patents

카나비제롤 유도체 Download PDF

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KR102422492B1
KR102422492B1 KR1020167025830A KR20167025830A KR102422492B1 KR 102422492 B1 KR102422492 B1 KR 102422492B1 KR 1020167025830 A KR1020167025830 A KR 1020167025830A KR 20167025830 A KR20167025830 A KR 20167025830A KR 102422492 B1 KR102422492 B1 KR 102422492B1
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South Korea
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formula
dimethyl
dienyl
octa
benzoquinone
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Expired - Fee Related
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KR1020167025830A
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Korean (ko)
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KR20160126006A (ko
Inventor
지오반니 아펜디노
마리아 루즈 벨리도 카벨로 드 알바
에듀라도 무노즈 블랑코
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에메랄드 헬스 파마수티컬스 아이엔씨.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/30—Quinones containing groups having oxygen atoms singly bound to carbon atoms with polycyclic non-condensed quinoid structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
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    • C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C07C225/26—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
    • C07C225/28—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of non-condensed quinone rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
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  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020167025830A 2014-02-27 2015-02-12 카나비제롤 유도체 Expired - Fee Related KR102422492B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14156954.1A EP2913321B1 (en) 2014-02-27 2014-02-27 Novel cannabigerol derivatives
EP14156954.1 2014-02-27
PCT/EP2015/053032 WO2015128200A1 (en) 2014-02-27 2015-02-12 Novel cannabigerol derivatives

Publications (2)

Publication Number Publication Date
KR20160126006A KR20160126006A (ko) 2016-11-01
KR102422492B1 true KR102422492B1 (ko) 2022-07-19

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KR1020167025830A Expired - Fee Related KR102422492B1 (ko) 2014-02-27 2015-02-12 카나비제롤 유도체

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US (1) US9802880B2 (enExample)
EP (1) EP2913321B1 (enExample)
JP (1) JP6619349B2 (enExample)
KR (1) KR102422492B1 (enExample)
CN (1) CN106061937B (enExample)
AU (1) AU2015222384B2 (enExample)
BR (1) BR112016019891B1 (enExample)
CA (1) CA2937275C (enExample)
DK (1) DK2913321T3 (enExample)
ES (1) ES2894760T3 (enExample)
IL (1) IL247149B (enExample)
MX (1) MX358084B (enExample)
RU (1) RU2684913C2 (enExample)
WO (1) WO2015128200A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3122714A1 (en) 2018-12-11 2020-06-18 Emerald Health Pharmaceuticals Inc Cannabigerol quinone acid and salts thereof
US12084407B2 (en) 2019-11-26 2024-09-10 Canopy Growth Corporation Cannabigerol derivatives and use thereof as cannabinoid receptor modulators
GR1010219B (el) * 2021-01-22 2022-04-08 Ekati Alchemy Lab Sl, Φαρμακευτικα προϊοντα βασισμενα σε εστερες κανναβινοειδων οξεων
WO2023059640A1 (en) * 2021-10-06 2023-04-13 Juva Life, Inc. Cannabigeroquinone compounds, compositions including such compounds, and uses of such compounds and compositions
US20250241934A1 (en) * 2024-01-22 2025-07-31 Miralogx Llc Synthetic Cannabigerol Quinone Analogs and Pharmaceutical Compositions Containing Same for Treating Neurological Disorders

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
FI102273B (fi) * 1989-09-11 1998-11-13 Eisai Co Ltd Kinonijohdannaiset, niiden valmistaminen ja niiden farmakologinen käyt tö
CA2570501A1 (en) * 2004-06-18 2006-01-26 Gergely Szakacs Methods for the identification and use of compounds suitable for the treatment of drug resistant cancer cells
EP2551255B1 (en) * 2010-03-26 2017-11-08 Vivacell Biotechnology España, S.L Cannabinoid quinone derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BIOCHIMICA AND BIOPHYSICA ACTA. MOLECULAR AND CELL BIOLOGY OF LI PIDS, 2007, 1771(8), pp.1094-1107

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Publication number Publication date
AU2015222384A1 (en) 2016-10-06
US20170247308A1 (en) 2017-08-31
ES2894760T3 (es) 2022-02-15
EP2913321B1 (en) 2021-07-21
MX2016010952A (es) 2017-02-02
RU2016132415A (ru) 2018-04-02
CN106061937A (zh) 2016-10-26
BR112016019891A2 (pt) 2017-10-24
CN106061937B (zh) 2021-07-27
JP6619349B2 (ja) 2019-12-11
EP2913321A1 (en) 2015-09-02
RU2684913C2 (ru) 2019-04-16
JP2017513810A (ja) 2017-06-01
KR20160126006A (ko) 2016-11-01
US9802880B2 (en) 2017-10-31
CA2937275C (en) 2022-03-29
DK2913321T3 (da) 2021-10-25
MX358084B (es) 2018-08-03
CA2937275A1 (en) 2015-09-03
RU2016132415A3 (enExample) 2018-09-28
AU2015222384B2 (en) 2019-04-18
IL247149A0 (en) 2016-09-29
BR112016019891B1 (pt) 2023-01-10
IL247149B (en) 2019-11-28
WO2015128200A1 (en) 2015-09-03

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