KR102410183B1 - 이소글리시리진산 또는 이의 염의 흡입용 제제, 및 호흡 기관 질환을 치료하기 위한 약물의 제조에서의 용도 - Google Patents

이소글리시리진산 또는 이의 염의 흡입용 제제, 및 호흡 기관 질환을 치료하기 위한 약물의 제조에서의 용도 Download PDF

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KR102410183B1
KR102410183B1 KR1020187033045A KR20187033045A KR102410183B1 KR 102410183 B1 KR102410183 B1 KR 102410183B1 KR 1020187033045 A KR1020187033045 A KR 1020187033045A KR 20187033045 A KR20187033045 A KR 20187033045A KR 102410183 B1 KR102410183 B1 KR 102410183B1
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inhalation
formulation
magnesium isoglycyrrhizinate
lactose
magnesium
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KR20180132143A (ko
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홍메이 구
샨천 왕
시퀀 장
레이 후앙
홍지앙 쉬
웨이 송
핑 동
종잉 선
잉 장
데양 첸
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치아타이 티안큉 파마수티컬 그룹 주식회사
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/08—Solutions
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

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  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020187033045A 2016-04-15 2017-04-14 이소글리시리진산 또는 이의 염의 흡입용 제제, 및 호흡 기관 질환을 치료하기 위한 약물의 제조에서의 용도 Active KR102410183B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201610237175.3 2016-04-15
CN201610237175 2016-04-15
PCT/CN2017/080583 WO2017177966A1 (zh) 2016-04-15 2017-04-14 异甘草酸或其盐的吸入制剂及其在制备治疗呼吸系统疾病药物中的应用

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KR20180132143A KR20180132143A (ko) 2018-12-11
KR102410183B1 true KR102410183B1 (ko) 2022-06-17

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US (2) US20190117568A1 (enExample)
EP (1) EP3443954B1 (enExample)
JP (2) JP7166929B2 (enExample)
KR (1) KR102410183B1 (enExample)
CN (2) CN111920785B (enExample)
AU (1) AU2017251548B2 (enExample)
BR (1) BR112018071208A2 (enExample)
EA (1) EA201892350A1 (enExample)
MX (1) MX394106B (enExample)
MY (1) MY204600A (enExample)
PH (1) PH12018502195A1 (enExample)
SG (2) SG11201809042SA (enExample)
WO (1) WO2017177966A1 (enExample)

Families Citing this family (1)

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CN119345161A (zh) * 2024-12-25 2025-01-24 江苏长泰药业股份有限公司 一种丙酮酸钠雾化吸入制剂及其制备方法和应用

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CN101190232A (zh) * 2006-11-30 2008-06-04 江苏正大天晴药业股份有限公司 一种注射用异甘草酸镁冻干粉针剂及其制备方法
CN103156930A (zh) * 2011-12-19 2013-06-19 张亚军 一种含芍药和甘草提取物的呼吸道给药制剂

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US4891221A (en) * 1988-11-23 1990-01-02 Edward Shanborm Whole blood antiviral process and composition
WO2005004913A1 (ja) 2003-07-09 2005-01-20 Anges Mg, Inc. デコイを含む薬学的組成物およびその使用方法
JP2009513529A (ja) * 2003-07-11 2009-04-02 グラクソ グループ リミテッド ステアリン酸マグネシウムを含む医薬製剤
CN101023953B (zh) * 2006-07-24 2010-05-12 南开大学 治疗支气管哮喘的组合物
JP2008222682A (ja) * 2007-03-15 2008-09-25 Kumamoto Univ 線維化肺疾患治療薬、気道粘液分泌細胞過形成抑制剤および気道塞栓治療薬
CN101396368B (zh) * 2007-09-29 2010-12-01 江苏正大天晴药业股份有限公司 异甘草酸或其盐在制备治疗过敏性鼻炎药物中的应用
CN101669962A (zh) * 2009-09-18 2010-03-17 杭州市第六人民医院 复合甘草酸氨基酸注射液及其制备方法和应用
CA2809031C (en) * 2010-08-25 2018-10-16 Weijian Zhang Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis
NZ627963A (en) * 2012-03-13 2015-08-28 Respivert Ltd Dry powder pharmaceutical formulations for inhalation of a compound that inhibits pi3 kinase
CN102920936A (zh) * 2012-09-17 2013-02-13 陈泉生 一种治疗呼吸道疾病的吸盐物及其制作方法
CN104042573A (zh) * 2014-06-03 2014-09-17 青岛市市立医院 一种异甘草酸镁冻干粉针剂及其制备方法
CN106237297A (zh) * 2016-08-30 2016-12-21 吉林紫鑫药业股份有限公司 一种用于治疗慢性支气管炎的药物组合物

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CN101190232A (zh) * 2006-11-30 2008-06-04 江苏正大天晴药业股份有限公司 一种注射用异甘草酸镁冻干粉针剂及其制备方法
CN103156930A (zh) * 2011-12-19 2013-06-19 张亚军 一种含芍药和甘草提取物的呼吸道给药制剂

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MX2018012461A (es) 2019-09-18
US20200368158A1 (en) 2020-11-26
US20190117568A1 (en) 2019-04-25
EP3443954A4 (en) 2019-11-20
JP7166929B2 (ja) 2022-11-08
EA201892350A1 (ru) 2019-06-28
MY204600A (en) 2024-09-05
PH12018502195A1 (en) 2019-09-23
MX394106B (es) 2025-03-24
JP2019511556A (ja) 2019-04-25
EP3443954B1 (en) 2026-02-25
US11534398B2 (en) 2022-12-27
CN111920785B (zh) 2022-05-20
SG11201809042SA (en) 2018-11-29
JP2021176903A (ja) 2021-11-11
CN109069442B (zh) 2020-09-04
BR112018071208A2 (pt) 2019-02-12
SG10202010192YA (en) 2020-11-27
KR20180132143A (ko) 2018-12-11
WO2017177966A1 (zh) 2017-10-19
CN109069442A (zh) 2018-12-21
JP7309791B2 (ja) 2023-07-18
AU2017251548B2 (en) 2022-02-17
EP3443954A1 (en) 2019-02-20
AU2017251548A1 (en) 2018-11-15
CN111920785A (zh) 2020-11-13

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