KR102408292B1 - 무스카린성 수용체 활성화에 의해 개선된 장애의 치료를 위한 조성물 및 방법 - Google Patents

무스카린성 수용체 활성화에 의해 개선된 장애의 치료를 위한 조성물 및 방법 Download PDF

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KR102408292B1
KR102408292B1 KR1020217011501A KR20217011501A KR102408292B1 KR 102408292 B1 KR102408292 B1 KR 102408292B1 KR 1020217011501 A KR1020217011501 A KR 1020217011501A KR 20217011501 A KR20217011501 A KR 20217011501A KR 102408292 B1 KR102408292 B1 KR 102408292B1
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exanomeline
beads
trospium
pharmaceutical composition
oral pharmaceutical
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KR20210062663A (ko
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에임스더 베탄쿠르
브루스 레렌더
로슈 띠베르
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카루나 세러퓨틱스 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
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    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020217011501A 2018-09-28 2019-09-27 무스카린성 수용체 활성화에 의해 개선된 장애의 치료를 위한 조성물 및 방법 Active KR102408292B1 (ko)

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US201862738333P 2018-09-28 2018-09-28
US62/738,333 2018-09-28
PCT/US2019/053429 WO2020069301A1 (en) 2018-09-28 2019-09-27 Compositions and methods for treating disorders ameliorated by muscarnic receptor activation

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KR20210062663A KR20210062663A (ko) 2021-05-31
KR102408292B1 true KR102408292B1 (ko) 2022-06-10

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US (7) US10933020B2 (enExample)
EP (1) EP3856182B1 (enExample)
JP (4) JP7096441B2 (enExample)
KR (1) KR102408292B1 (enExample)
CN (2) CN115581696A (enExample)
AU (3) AU2019346626B2 (enExample)
BR (1) BR112021005802B1 (enExample)
CA (2) CA3114623C (enExample)
CL (2) CL2021000723A1 (enExample)
CO (1) CO2021005261A2 (enExample)
CR (1) CR20210212A (enExample)
EA (1) EA202190356A1 (enExample)
IL (3) IL295341B2 (enExample)
LT (1) LT3856182T (enExample)
MX (1) MX391629B (enExample)
NZ (1) NZ773719A (enExample)
PH (1) PH12021550616A1 (enExample)
SA (1) SA521421595B1 (enExample)
SG (1) SG11202102349PA (enExample)
UA (1) UA128017C2 (enExample)
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CN118267380B (zh) * 2024-05-31 2024-08-27 北京普诺旺康医药科技有限公司 呫诺美林-曲司氯铵缓释微球胶囊及其制备方法
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