KR102392347B1 - 경구 붕해 정제 - Google Patents

경구 붕해 정제 Download PDF

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Publication number
KR102392347B1
KR102392347B1 KR1020187033221A KR20187033221A KR102392347B1 KR 102392347 B1 KR102392347 B1 KR 102392347B1 KR 1020187033221 A KR1020187033221 A KR 1020187033221A KR 20187033221 A KR20187033221 A KR 20187033221A KR 102392347 B1 KR102392347 B1 KR 102392347B1
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South Korea
Prior art keywords
tablet
delete delete
tablets
weight
ticagrelor
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KR1020187033221A
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English (en)
Korean (ko)
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KR20180132147A (ko
Inventor
파르한 압델 카림 모함마드 알 후스반
라르스 하칸 크리스테르 글라드
옌뉘 말린 크리스티나 할스테인
안드레아 제인 모이어
마이클 피터 톰슨
Original Assignee
아스트라제네카 아베
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58640851&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102392347(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Priority to KR1020227013818A priority Critical patent/KR102488486B1/ko
Publication of KR20180132147A publication Critical patent/KR20180132147A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Mechanical Engineering (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020187033221A 2016-04-21 2017-04-20 경구 붕해 정제 Active KR102392347B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227013818A KR102488486B1 (ko) 2016-04-21 2017-04-20 경구 붕해 정제

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662325584P 2016-04-21 2016-04-21
US62/325,584 2016-04-21
PCT/EP2017/059443 WO2017182589A1 (en) 2016-04-21 2017-04-20 Orally disintegrating tablets

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227013818A Division KR102488486B1 (ko) 2016-04-21 2017-04-20 경구 붕해 정제

Publications (2)

Publication Number Publication Date
KR20180132147A KR20180132147A (ko) 2018-12-11
KR102392347B1 true KR102392347B1 (ko) 2022-05-02

Family

ID=58640851

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020187033221A Active KR102392347B1 (ko) 2016-04-21 2017-04-20 경구 붕해 정제
KR1020227013818A Active KR102488486B1 (ko) 2016-04-21 2017-04-20 경구 붕해 정제

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020227013818A Active KR102488486B1 (ko) 2016-04-21 2017-04-20 경구 붕해 정제

Country Status (26)

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US (1) US10729655B2 (enExample)
EP (2) EP4417537A3 (enExample)
JP (2) JP6960941B2 (enExample)
KR (2) KR102392347B1 (enExample)
CN (3) CN107595789B (enExample)
AU (2) AU2017253367B2 (enExample)
BR (1) BR112018071440A2 (enExample)
CO (1) CO2018012431A2 (enExample)
DK (1) DK3445338T3 (enExample)
EA (1) EA201892150A1 (enExample)
ES (1) ES3014055T3 (enExample)
FI (1) FI3445338T3 (enExample)
HR (1) HRP20250204T1 (enExample)
HU (1) HUE070095T2 (enExample)
IL (1) IL262312B (enExample)
LT (1) LT3445338T (enExample)
MA (1) MA44720B1 (enExample)
PE (1) PE20190372A1 (enExample)
PH (1) PH12018502226A1 (enExample)
PL (1) PL3445338T3 (enExample)
PT (1) PT3445338T (enExample)
RS (1) RS66536B1 (enExample)
SG (2) SG10202107682QA (enExample)
SI (1) SI3445338T1 (enExample)
SM (1) SMT202500081T1 (enExample)
WO (1) WO2017182589A1 (enExample)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
CN111450067A (zh) * 2019-01-18 2020-07-28 北京万全德众医药生物技术有限公司 一种替格瑞洛分散片及其制备方法
CN109700773B (zh) * 2019-03-01 2021-03-16 石药集团中奇制药技术（石家庄）有限公司 一种替格瑞洛制剂组合物及其制备方法
JP7657041B2 (ja) 2020-08-19 2025-04-04 アストラゼネカ・アクチエボラーグ 併用療法
CN114712317A (zh) * 2021-01-04 2022-07-08 弘和制药有限公司 一种替格瑞洛药物组合物及其制备方法和其应用
US20220387328A1 (en) * 2021-06-04 2022-12-08 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Dosage form for nicotine replacement therapy
WO2023057879A1 (en) * 2021-10-04 2023-04-13 Neurim Pharmaceuticals (1991) Ltd. Methods and products for treating subjects with autism spectrum disorders
CN120129530A (zh) 2022-10-28 2025-06-10 阿斯利康(瑞典)有限公司 以40mg至240mg的剂量用于在治疗缺血事件中使用的重组腺苷三磷酸双磷酸酶蛋白
CN116370423B (zh) * 2023-02-28 2024-11-12 天津力生制药股份有限公司 一种替格瑞洛口腔崩解片及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058889A (zh) * 2010-11-05 2011-05-18 王定豪 包含抗凝血类药物的分散片及其应用

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DE2246013A1 (de) 1972-09-20 1974-03-28 Boehringer Mannheim Gmbh Verfahren zur herstellung von poroesen tabletten
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB0013407D0 (en) 2000-06-02 2000-07-26 Astrazeneca Ab Forms of a chemical compound
ES2268020T3 (es) * 2001-05-10 2007-03-16 Astellas Pharma Inc. Comprimidos de disgregacion rapida de la cavidad oral y proceso para producir los mismos.
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
CN2717851Y (zh) 2004-05-14 2005-08-17 重庆康刻尔制药有限公司 一种药品包装板
TWI482772B (zh) 2006-08-21 2015-05-01 Astrazeneca Ab 適合口服且包含三唑并[4,5-d]嘧啶衍生物之組合物
FR2968992B1 (fr) 2010-12-16 2013-02-08 Sanofi Aventis Comprime pharmaceutique orodispersible a base de zolpidem
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Also Published As

Publication number Publication date
EP4417537A2 (en) 2024-08-21
HRP20250204T1 (hr) 2025-04-11
JP2022009050A (ja) 2022-01-14
CN107595789A (zh) 2018-01-19
PE20190372A1 (es) 2019-03-08
JP6960941B2 (ja) 2021-11-05
CN107530288B (zh) 2022-01-25
WO2017182589A9 (en) 2018-04-19
AU2020201930B2 (en) 2020-10-29
EA201892150A1 (ru) 2019-05-31
SG10202107682QA (en) 2021-08-30
PL3445338T3 (pl) 2025-03-31
CO2018012431A2 (es) 2018-11-30
CN107530288A (zh) 2018-01-02
WO2017182589A1 (en) 2017-10-26
HUE070095T2 (hu) 2025-05-28
CN107595789B (zh) 2021-01-15
AU2017253367B2 (en) 2020-04-16
RS66536B1 (sr) 2025-03-31
KR20180132147A (ko) 2018-12-11
PH12018502226A1 (en) 2019-07-29
MA44720B1 (fr) 2025-02-28
PT3445338T (pt) 2025-03-03
DK3445338T3 (da) 2025-02-10
CN107595790A (zh) 2018-01-19
US10729655B2 (en) 2020-08-04
SMT202500081T1 (it) 2025-03-12
MA44720A (fr) 2019-02-27
KR20220054907A (ko) 2022-05-03
SG11201808996SA (en) 2018-11-29
JP7254871B2 (ja) 2023-04-10
ES3014055T3 (en) 2025-04-16
FI3445338T3 (fi) 2025-01-29
KR102488486B1 (ko) 2023-01-12
AU2017253367A1 (en) 2018-11-08
JP2019516674A (ja) 2019-06-20
EP3445338A1 (en) 2019-02-27
LT3445338T (lt) 2025-02-25
US20190117577A1 (en) 2019-04-25
IL262312A (en) 2018-11-29
EP3445338B1 (en) 2024-11-27
HK1249732A1 (zh) 2018-11-09
IL262312B (en) 2022-08-01
HK1248562A1 (zh) 2018-10-19
EP4417537A3 (en) 2024-12-04
AU2020201930A1 (en) 2020-04-09
CN107595790B (zh) 2021-01-12
BR112018071440A2 (pt) 2019-02-05
SI3445338T1 (sl) 2025-03-31

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