KR102372599B1 - Rxr 아고니스트로서의 치환 바이시클릭 헤테로아릴 화합물 - Google Patents

Rxr 아고니스트로서의 치환 바이시클릭 헤테로아릴 화합물 Download PDF

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KR102372599B1
KR102372599B1 KR1020167022235A KR20167022235A KR102372599B1 KR 102372599 B1 KR102372599 B1 KR 102372599B1 KR 1020167022235 A KR1020167022235 A KR 1020167022235A KR 20167022235 A KR20167022235 A KR 20167022235A KR 102372599 B1 KR102372599 B1 KR 102372599B1
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unsubstituted
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tetrahydro
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KR20160125958A (ko
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마드하반 구람 랑가
자간나트 마다나할리 랑가나트 라오
찬드라 세카르 구들라
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커넥시오스 라이프 사이언시즈 피브이티. 리미티드
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    • C07—ORGANIC CHEMISTRY
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    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
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    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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KR1020167022235A 2014-01-14 2015-01-09 Rxr 아고니스트로서의 치환 바이시클릭 헤테로아릴 화합물 Expired - Fee Related KR102372599B1 (ko)

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Application Number Priority Date Filing Date Title
IN161CH2014 2014-01-14
IN161/CHE/2014 2014-01-14
PCT/IN2015/000010 WO2015107549A1 (en) 2014-01-14 2015-01-09 Substituted bicyclic heteroaryl compounds as rxr agonists

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KR20160125958A KR20160125958A (ko) 2016-11-01
KR102372599B1 true KR102372599B1 (ko) 2022-03-10

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US (1) US9862713B2 (https=)
EP (1) EP3094626B1 (https=)
JP (1) JP6625057B2 (https=)
KR (1) KR102372599B1 (https=)
CN (1) CN107074800B (https=)
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