KR102361801B1 - 발렌토닌을 함유하는 경피 치료 시스템 및 약제로서의 그것의 사용 - Google Patents

발렌토닌을 함유하는 경피 치료 시스템 및 약제로서의 그것의 사용 Download PDF

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Publication number
KR102361801B1
KR102361801B1 KR1020177024343A KR20177024343A KR102361801B1 KR 102361801 B1 KR102361801 B1 KR 102361801B1 KR 1020177024343 A KR1020177024343 A KR 1020177024343A KR 20177024343 A KR20177024343 A KR 20177024343A KR 102361801 B1 KR102361801 B1 KR 102361801B1
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South Korea
Prior art keywords
vlt
melatonin
valentonin
patch
plasma
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Expired - Fee Related
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KR1020177024343A
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English (en)
Korean (ko)
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KR20180004100A (ko
Inventor
장-베르나르 푸르틸란
마리안느 푸르틸란
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쏘 요세파 메넨데즈
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020177024343A 2015-02-04 2016-02-04 발렌토닌을 함유하는 경피 치료 시스템 및 약제로서의 그것의 사용 Expired - Fee Related KR102361801B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15305161 2015-02-04
EP15305161.0 2015-02-04
PCT/EP2016/052376 WO2016124688A1 (fr) 2015-02-04 2016-02-04 Systeme therapeutique transdermique contenant de la valentonine et son utilisation comme medicament

Publications (2)

Publication Number Publication Date
KR20180004100A KR20180004100A (ko) 2018-01-10
KR102361801B1 true KR102361801B1 (ko) 2022-02-10

Family

ID=52573642

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177024343A Expired - Fee Related KR102361801B1 (ko) 2015-02-04 2016-02-04 발렌토닌을 함유하는 경피 치료 시스템 및 약제로서의 그것의 사용

Country Status (9)

Country Link
US (1) US10744122B2 (https=)
EP (1) EP3253378B1 (https=)
JP (1) JP6785779B2 (https=)
KR (1) KR102361801B1 (https=)
CN (1) CN107810003B (https=)
CA (1) CA2975985A1 (https=)
ES (1) ES2738633T3 (https=)
HU (1) HUE045679T2 (https=)
WO (1) WO2016124688A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007101863A1 (fr) * 2006-03-08 2007-09-13 Macef Association therapeutique d'un antagoniste du recepteur 5ht2 et d'activateur du recepteur 5ht2

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2116036A1 (en) * 1991-10-18 1993-04-29 F. Eugene Yates Device for the transdermal administration of melatonin
DE4134493A1 (de) * 1991-10-18 1993-04-22 Teves Gmbh Alfred Blockiergeschuetzte hydraulische bremsanlage
FR2724384B1 (fr) 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
ATE443526T1 (de) * 1999-08-20 2009-10-15 Takeda Pharmaceutical Zusammensetzung für perkutane absorption mit einem melantoninrezeptor-agonistisch wirkendem wirkstoff
IL155666A (en) * 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
FR2912405A1 (fr) * 2007-02-08 2008-08-15 Fourtillan Snc Derives des imidazo[1',5':1,6]pyrido[3,4-b]indoles et leur utilisation en therapeutique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007101863A1 (fr) * 2006-03-08 2007-09-13 Macef Association therapeutique d'un antagoniste du recepteur 5ht2 et d'activateur du recepteur 5ht2

Also Published As

Publication number Publication date
HUE045679T2 (hu) 2020-01-28
KR20180004100A (ko) 2018-01-10
WO2016124688A1 (fr) 2016-08-11
JP6785779B2 (ja) 2020-11-18
CN107810003B (zh) 2022-05-03
JP2018507850A (ja) 2018-03-22
US10744122B2 (en) 2020-08-18
CA2975985A1 (fr) 2016-08-11
CN107810003A (zh) 2018-03-16
ES2738633T3 (es) 2020-01-24
EP3253378B1 (fr) 2019-05-08
EP3253378A1 (fr) 2017-12-13
US20180000796A1 (en) 2018-01-04

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KR102361801B1 (ko) 발렌토닌을 함유하는 경피 치료 시스템 및 약제로서의 그것의 사용
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