KR102307275B1 - 아나모렐린 기반의 의학적 치료 - Google Patents

아나모렐린 기반의 의학적 치료 Download PDF

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KR102307275B1
KR102307275B1 KR1020217008765A KR20217008765A KR102307275B1 KR 102307275 B1 KR102307275 B1 KR 102307275B1 KR 1020217008765 A KR1020217008765 A KR 1020217008765A KR 20217008765 A KR20217008765 A KR 20217008765A KR 102307275 B1 KR102307275 B1 KR 102307275B1
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anamorelin
patients
patient
cancer
cachexia
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Korean (ko)
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KR20210035923A (ko
Inventor
윌리엄 만
존 프렌드
윌리엄 폴비노
수잔 알렌
밍 루
엘리자베쓰 두스
루벤 조르지노
엔리코 바로니
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헬신 헬쓰케어 에스.에이.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020217008765A 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료 Active KR102307275B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462045976P 2014-09-04 2014-09-04
US62/045,976 2014-09-04
PCT/US2015/047435 WO2016036598A1 (en) 2014-09-04 2015-08-28 Medical treatments based on anamorelin
KR1020187020062A KR102234319B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료

Related Parent Applications (1)

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KR1020187020062A Division KR102234319B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료

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KR20210035923A KR20210035923A (ko) 2021-04-01
KR102307275B1 true KR102307275B1 (ko) 2021-09-30

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KR1020217008765A Active KR102307275B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료
KR1020177008748A Active KR101881264B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료
KR1020187020062A Active KR102234319B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료

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KR1020177008748A Active KR101881264B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료
KR1020187020062A Active KR102234319B1 (ko) 2014-09-04 2015-08-28 아나모렐린 기반의 의학적 치료

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US (5) US9675600B2 (enExample)
EP (2) EP3590338A3 (enExample)
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Families Citing this family (9)

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WO2014159609A1 (en) 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
CN113577074A (zh) 2014-09-04 2021-11-02 赫尔森保健股份公司 基于阿拉莫林的药物治疗
EP3836801A4 (en) 2018-08-16 2022-05-18 Société des Produits Nestlé S.A. Peanut oral immunotherapy with maintenance dose
AU2019401214B2 (en) 2018-12-20 2025-09-04 Société des Produits Nestlé S.A. Peanut oral immunotherapy dosing schedule for missed doses
US11229673B2 (en) 2019-05-10 2022-01-25 Société des Produits Nestlé S.A. Methods for improving the quality of life of a patient with a peanut allergy
KR20220054244A (ko) 2019-08-30 2022-05-02 헬신 헬스케어 에스아 개선된 안정성을 갖는 아나모렐린 정제의 제조 방법
US20240139176A1 (en) * 2019-10-24 2024-05-02 Toray Industries, Inc. Methods of treating or preventing cachexia
JP2024534464A (ja) * 2021-09-17 2024-09-20 小野薬品工業株式会社 食欲不振/悪液質患者における患者報告アウトカムに関する臨床的に意味のある改善を判定し、提供する方法
WO2025004650A1 (ja) * 2023-06-28 2025-01-02 日清オイリオグループ株式会社 中高年者の疲労感を軽減するための剤及び組成物

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US20070004638A1 (en) 2004-06-29 2007-01-04 Rejuvenon Corporation Crystal forms of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
US20080207640A1 (en) 2007-02-13 2008-08-28 Sapphire Therapeutics Method of treating cell proliferative disorders using growth hormone secretagogues
US20080300194A1 (en) 2007-04-10 2008-12-04 Sapphire Therapeutics, Inc. Methods of treating emesis using growth hormone secretagogues
WO2013158874A1 (en) 2012-04-20 2013-10-24 Helsinn Healthcare Sa Methods of producing anamorelin hydrochloride having controlled chloride content

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KR20070010151A (ko) 2004-03-30 2007-01-22 사파이어 세라퓨틱스, 인크. 성장 호르몬 분비촉진제를 이용하여 c-반응성 단백질을감소시키는 방법
US20150099709A1 (en) * 2012-05-25 2015-04-09 Raqualia Pharma Inc. Ghrelin receptor agonists for the treatment of achlorhydria
CN113577074A (zh) 2014-09-04 2021-11-02 赫尔森保健股份公司 基于阿拉莫林的药物治疗

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US20080207640A1 (en) 2007-02-13 2008-08-28 Sapphire Therapeutics Method of treating cell proliferative disorders using growth hormone secretagogues
US20080300194A1 (en) 2007-04-10 2008-12-04 Sapphire Therapeutics, Inc. Methods of treating emesis using growth hormone secretagogues
WO2013158874A1 (en) 2012-04-20 2013-10-24 Helsinn Healthcare Sa Methods of producing anamorelin hydrochloride having controlled chloride content

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DK3188599T3 (da) 2019-11-25
EA201790352A1 (ru) 2017-07-31
MD4710B1 (ro) 2020-09-30
WO2016036598A1 (en) 2016-03-10
LT3188599T (lt) 2019-12-10
MD4710C1 (ro) 2021-04-30
KR20180085047A (ko) 2018-07-25
PL3188599T3 (pl) 2020-06-01
CN107205389A (zh) 2017-09-26
AR103118A1 (es) 2017-04-19
KR102234319B1 (ko) 2021-04-01
CR20170121A (es) 2017-07-17
TW201613587A (en) 2016-04-16
MX361741B (es) 2018-12-14
CY1122746T1 (el) 2021-03-12
TWI639429B (zh) 2018-11-01
MX2017002825A (es) 2017-09-28
UA120765C2 (uk) 2020-02-10
DOP2017000055A (es) 2017-08-15
EA035578B1 (ru) 2020-07-09
GEP20186939B (en) 2018-12-25
US10894041B2 (en) 2021-01-19
EP3188599A4 (en) 2017-10-11
US9675600B2 (en) 2017-06-13
JP2018154655A (ja) 2018-10-04
JP2017526695A (ja) 2017-09-14
EP3590338A2 (en) 2020-01-08
US20190175574A1 (en) 2019-06-13
CN109172575A (zh) 2019-01-11
NI201700024A (es) 2017-07-18
ME03597B (me) 2020-07-20
JP2021080281A (ja) 2021-05-27
BR112017003552A2 (pt) 2017-12-05
PH12017500392B1 (en) 2018-08-31
EP3188599B1 (en) 2019-10-02
SG11201701567UA (en) 2017-03-30
JP6923486B2 (ja) 2021-08-18
ES2761777T3 (es) 2020-05-21
CA2959158A1 (en) 2016-03-10
MY187167A (en) 2021-09-07
CO2017003263A2 (es) 2017-07-28
NZ729673A (en) 2023-09-29
EP3590338A3 (en) 2020-03-18
CN113577074A (zh) 2021-11-02
US20240024303A1 (en) 2024-01-25
US20170296526A1 (en) 2017-10-19
KR20170047372A (ko) 2017-05-04
SI3188599T1 (sl) 2020-02-28
US11723902B2 (en) 2023-08-15
HRP20192345T1 (hr) 2020-03-20
PH12017500392A1 (en) 2017-07-17
UY36286A (es) 2016-02-29
AP2017009772A0 (en) 2017-02-28
RS59751B1 (sr) 2020-02-28
KR101881264B1 (ko) 2018-07-23
SV2017005400A (es) 2017-04-20
AU2015312231B2 (en) 2017-10-19
AU2015312231A1 (en) 2017-03-23
CL2017000494A1 (es) 2017-09-15
JP6356907B2 (ja) 2018-07-11
JP7044918B2 (ja) 2022-03-30
CN113577073A (zh) 2021-11-02
PE20171109A1 (es) 2017-08-07
PT3188599T (pt) 2020-01-15
US20210093627A1 (en) 2021-04-01
MA40607B1 (fr) 2019-11-29
IL250692B (en) 2019-05-30
IL250692A0 (en) 2017-04-30
KR20210035923A (ko) 2021-04-01
US10278964B2 (en) 2019-05-07
ECSP17019893A (es) 2017-05-31
JO3541B1 (ar) 2020-07-05
TN2017000040A1 (en) 2018-07-04
US20160067236A1 (en) 2016-03-10
EP3188599A1 (en) 2017-07-12
CN107375285A (zh) 2017-11-24
HUE046894T2 (hu) 2020-04-28
MD20170025A2 (ro) 2017-07-31

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