KR102241660B1 - 다한증 치료용 항콜린성 글리코피롤레이트 에스테르 - Google Patents
다한증 치료용 항콜린성 글리코피롤레이트 에스테르 Download PDFInfo
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- KR102241660B1 KR102241660B1 KR1020207015539A KR20207015539A KR102241660B1 KR 102241660 B1 KR102241660 B1 KR 102241660B1 KR 1020207015539 A KR1020207015539 A KR 1020207015539A KR 20207015539 A KR20207015539 A KR 20207015539A KR 102241660 B1 KR102241660 B1 KR 102241660B1
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- hydroxyacetoxy
- cyclopentyl
- phenyl
- compound
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Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
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- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201361798073P | 2013-03-15 | 2013-03-15 | |
| US61/798,073 | 2013-03-15 | ||
| PCT/US2014/028332 WO2014144075A1 (en) | 2013-03-15 | 2014-03-14 | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
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| KR1020197034502A Division KR102153457B1 (ko) | 2013-03-15 | 2014-03-14 | 다한증 치료용 항콜린성 글리코피롤레이트 에스테르 |
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| AU2014227923B2 (en) * | 2013-03-15 | 2019-02-14 | Bodor Laboratories, Inc. | Method of dosing and use of soft anticholinergic esters |
| US20150259283A1 (en) | 2014-03-13 | 2015-09-17 | Brickell Biotech, Inc. | Formulation for soft anticholinergic analogs |
| JP2017507959A (ja) | 2014-03-13 | 2017-03-23 | ボドール ラボラトリーズ， インコーポレイテッド | 選択された抗コリン作動性両性イオンの使用 |
| WO2016175240A1 (ja) * | 2015-04-30 | 2016-11-03 | 久光製薬株式会社 | 多汗症治療用外用剤 |
| CN119033770A (zh) * | 2015-07-21 | 2024-11-29 | 博多尔实验仪器公司 | 软性抗胆碱能药类似物的制剂 |
| MY197265A (en) | 2015-09-11 | 2023-06-08 | Bodor Laboratories Inc | Methods and compositions for soft anticholinergic esters |
| US20180235869A1 (en) * | 2015-09-11 | 2018-08-23 | Bodor Laboratories, Inc. | Methods and compositions for soft anticholinergic zwitterions |
| CA3029621A1 (en) * | 2016-07-01 | 2018-01-04 | Bodor Laboratories, Inc. | Compositions and methods for treatment of copd |
| TWI767507B (zh) | 2016-07-21 | 2022-06-11 | 美商波德實驗股份有限公司 | 軟性抗膽鹼類似物之製劑 |
| KR101951021B1 (ko) | 2017-02-06 | 2019-02-22 | 주식회사 퍼슨 | 발한억제 기능을 가지는 자외선 차단 화장료 조성물 및 이를 사용한 자외선 차단제의 제조방법 |
| HUE047368T2 (hu) * | 2017-07-17 | 2020-04-28 | Dr August Wolff Gmbh & Co Kg Arzneimittel | Olaj-a-vízben emulzió |
| US20210290536A1 (en) | 2018-07-24 | 2021-09-23 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Topical emulsion of an anticholinergic compound |
| SG10201912063PA (en) * | 2019-12-12 | 2021-07-29 | Nat Skin Centre Singapore Pte Ltd | A pharmaceutical formulation |
| JPWO2021177257A1 (enExample) | 2020-03-03 | 2021-09-10 | ||
| TW202146009A (zh) | 2020-03-03 | 2021-12-16 | 日商科研製藥股份有限公司 | 含有溴化索非羅銨的醫藥 |
| EP4260852A1 (en) | 2022-04-14 | 2023-10-18 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Topical formulation of an anticholinergic compound for treating severe hyperhidrosis and excessive sweating |
| WO2023198876A1 (en) | 2022-04-14 | 2023-10-19 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Topical formulation of an anticholinergic compound for treating severe hyperhidrosis and excessive sweating |
| KR102611847B1 (ko) * | 2023-03-27 | 2023-12-12 | 주식회사 이플라스크 | 무스카린 수용체 길항 활성을 갖는 신규한 피롤리디늄 화합물 및 이의 용도 |
Citations (2)
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|---|---|---|---|---|
| WO2007058971A2 (en) * | 2005-11-10 | 2007-05-24 | Bodor Nicholas S | Soft anticholinergic esters |
| WO2009051818A1 (en) | 2007-10-18 | 2009-04-23 | Stiefel Research Australia Pty Ltd | Topical glycopyrrolate formulations |
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| US5292530A (en) | 1991-06-02 | 1994-03-08 | Helene Curtis, Inc. | Stable anhydrous topically-active composition and suspending agent therefor |
| CA2461696A1 (en) | 2001-09-26 | 2003-04-03 | Alison B. Lukacsko | Compositions and methods for inhibiting eccrine perspiration in humans |
| US8252316B2 (en) | 2002-05-03 | 2012-08-28 | Purepharm Inc. | Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating |
| GB0428416D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| GB0428418D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| US7399861B2 (en) | 2005-11-10 | 2008-07-15 | Bodor Nicholas S | Soft anticholinergic esters |
| US8071693B2 (en) | 2006-06-22 | 2011-12-06 | Sabic Innovative Plastics Ip B.V. | Polysiloxane/polyimide copolymers and blends thereof |
| AU2014227923B2 (en) * | 2013-03-15 | 2019-02-14 | Bodor Laboratories, Inc. | Method of dosing and use of soft anticholinergic esters |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007058971A2 (en) * | 2005-11-10 | 2007-05-24 | Bodor Nicholas S | Soft anticholinergic esters |
| WO2009051818A1 (en) | 2007-10-18 | 2009-04-23 | Stiefel Research Australia Pty Ltd | Topical glycopyrrolate formulations |
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