SG11201507602SA - Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis - Google Patents
Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosisInfo
- Publication number
- SG11201507602SA SG11201507602SA SG11201507602SA SG11201507602SA SG11201507602SA SG 11201507602S A SG11201507602S A SG 11201507602SA SG 11201507602S A SG11201507602S A SG 11201507602SA SG 11201507602S A SG11201507602S A SG 11201507602SA SG 11201507602S A SG11201507602S A SG 11201507602SA
- Authority
- SG
- Singapore
- Prior art keywords
- hyperhidrosis
- esters
- treatment
- glycopyrrolate
- anticholinergic
- Prior art date
Links
- VPNYRYCIDCJBOM-UHFFFAOYSA-M Glycopyrronium bromide Chemical class [Br-].C1[N+](C)(C)CCC1OC(=O)C(O)(C=1C=CC=CC=1)C1CCCC1 VPNYRYCIDCJBOM-UHFFFAOYSA-M 0.000 title 1
- 208000008454 Hyperhidrosis Diseases 0.000 title 1
- 230000001078 anti-cholinergic effect Effects 0.000 title 1
- 230000037315 hyperhidrosis Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798073P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/028332 WO2014144075A1 (en) | 2013-03-15 | 2014-03-14 | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201507602SA true SG11201507602SA (en) | 2015-10-29 |
Family
ID=50625156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507602SA SG11201507602SA (en) | 2013-03-15 | 2014-03-14 | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US9220707B2 (en) |
| EP (1) | EP2968267B1 (en) |
| JP (4) | JP6223543B2 (en) |
| KR (4) | KR102050299B1 (en) |
| CN (2) | CN109364066A (en) |
| AU (1) | AU2014227923B2 (en) |
| BR (1) | BR112015023153A2 (en) |
| CA (1) | CA2904724C (en) |
| DK (1) | DK2968267T3 (en) |
| ES (1) | ES2673098T3 (en) |
| HK (2) | HK1217177A1 (en) |
| HU (1) | HUE038448T2 (en) |
| IL (1) | IL241307B (en) |
| MX (1) | MX363601B (en) |
| MY (1) | MY192033A (en) |
| PH (1) | PH12015501987A1 (en) |
| PL (1) | PL2968267T3 (en) |
| PT (1) | PT2968267T (en) |
| SG (1) | SG11201507602SA (en) |
| TR (1) | TR201808040T4 (en) |
| WO (1) | WO2014144075A1 (en) |
| ZA (1) | ZA201506834B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102050299B1 (en) * | 2013-03-15 | 2019-11-29 | 보도르 라보래토리즈, 인크. | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
| US20150259283A1 (en) | 2014-03-13 | 2015-09-17 | Brickell Biotech, Inc. | Formulation for soft anticholinergic analogs |
| WO2015138700A1 (en) * | 2014-03-13 | 2015-09-17 | Bodor Laboratories, Inc. | Use of selected anticholinergic zwitterions |
| ES2861052T3 (en) * | 2015-04-30 | 2021-10-05 | Hisamitsu Pharmaceutical Co | Topical composition comprising oxybutynin for the treatment of hyperhidrosis |
| PL3325487T3 (en) * | 2015-07-21 | 2021-12-13 | Bodor Laboratories, Inc. | Formulation for soft anticholinergic analogs |
| CA2998353A1 (en) * | 2015-09-11 | 2017-03-16 | Bodor Laboratories, Inc. | Methods and compositions for soft anticholinergic zwitterions |
| JP7270958B2 (en) | 2015-09-11 | 2023-05-11 | ボドール ラボラトリーズ， インコーポレイテッド | Methods and compositions for low toxicity anticholinergic esters |
| CA3029621A1 (en) * | 2016-07-01 | 2018-01-04 | Bodor Laboratories, Inc. | Compositions and methods for treatment of copd |
| TWI719046B (en) * | 2016-07-21 | 2021-02-21 | 美商波德實驗股份有限公司 | Formulation for soft anticholinergic analogs |
| KR101951021B1 (en) | 2017-02-06 | 2019-02-22 | 주식회사 퍼슨 | UV blocking cosmetic composition having an antiperspirant function and preparing process for UV blocking agents using the same |
| EP3431072B1 (en) * | 2017-07-17 | 2019-11-06 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Oil in water emulsion |
| US20210290536A1 (en) | 2018-07-24 | 2021-09-23 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Topical emulsion of an anticholinergic compound |
| SG10201912063PA (en) * | 2019-12-12 | 2021-07-29 | Nat Skin Centre Singapore Pte Ltd | A pharmaceutical formulation |
| WO2021177257A1 (en) | 2020-03-03 | 2021-09-10 | 科研製薬株式会社 | Method for treating primary axillary hyperhidrosis and pharmaceutical product therefor |
| CA3174550A1 (en) | 2020-03-03 | 2021-09-10 | Kaken Pharmaceutical Co., Ltd. | Medicament containing sofpironium bromide |
| EP4260852A1 (en) | 2022-04-14 | 2023-10-18 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Topical formulation of an anticholinergic compound for treating severe hyperhidrosis and excessive sweating |
| EP4333831B1 (en) | 2022-04-14 | 2024-08-14 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Topical formulation of an anticholinergic compound for treating severe hyperhidrosis and excessive sweating |
| KR102611847B1 (en) * | 2023-03-27 | 2023-12-12 | 주식회사 이플라스크 | Novel pyrrolidinium compounds having antagonistic activity against muscarinic receptors and use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292530A (en) | 1991-06-02 | 1994-03-08 | Helene Curtis, Inc. | Stable anhydrous topically-active composition and suspending agent therefor |
| CA2461696A1 (en) | 2001-09-26 | 2003-04-03 | Alison B. Lukacsko | Compositions and methods for inhibiting eccrine perspiration in humans |
| US8252316B2 (en) | 2002-05-03 | 2012-08-28 | Purepharm Inc. | Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating |
| GB0428418D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| GB0428416D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| WO2007059021A1 (en) * | 2005-11-10 | 2007-05-24 | Bodor Nicholas S | Soft anticholinergic zwitterions |
| ATE529399T1 (en) | 2005-11-10 | 2011-11-15 | Nicholas S Bodor | GENTLE ANTICHOLINER ESTERS |
| US8071693B2 (en) | 2006-06-22 | 2011-12-06 | Sabic Innovative Plastics Ip B.V. | Polysiloxane/polyimide copolymers and blends thereof |
| WO2009051818A1 (en) | 2007-10-18 | 2009-04-23 | Stiefel Research Australia Pty Ltd | Topical glycopyrrolate formulations |
| KR102050299B1 (en) * | 2013-03-15 | 2019-11-29 | 보도르 라보래토리즈, 인크. | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
-
2014
- 2014-03-14 KR KR1020157028470A patent/KR102050299B1/en active IP Right Grant
- 2014-03-14 WO PCT/US2014/028332 patent/WO2014144075A1/en active Application Filing
- 2014-03-14 US US14/213,242 patent/US9220707B2/en active Active
- 2014-03-14 PL PL14720386T patent/PL2968267T3/en unknown
- 2014-03-14 KR KR1020217010876A patent/KR20210043742A/en not_active Application Discontinuation
- 2014-03-14 EP EP14720386.3A patent/EP2968267B1/en active Active
- 2014-03-14 SG SG11201507602SA patent/SG11201507602SA/en unknown
- 2014-03-14 MX MX2015012072A patent/MX363601B/en unknown
- 2014-03-14 TR TR2018/08040T patent/TR201808040T4/en unknown
- 2014-03-14 PT PT147203863T patent/PT2968267T/en unknown
- 2014-03-14 AU AU2014227923A patent/AU2014227923B2/en active Active
- 2014-03-14 BR BR112015023153A patent/BR112015023153A2/en not_active Application Discontinuation
- 2014-03-14 CN CN201811323473.XA patent/CN109364066A/en active Pending
- 2014-03-14 CA CA2904724A patent/CA2904724C/en active Active
- 2014-03-14 KR KR1020207015539A patent/KR102241660B1/en active IP Right Grant
- 2014-03-14 ES ES14720386.3T patent/ES2673098T3/en active Active
- 2014-03-14 CN CN201480015677.0A patent/CN105050596A/en active Pending
- 2014-03-14 DK DK14720386.3T patent/DK2968267T3/en active
- 2014-03-14 JP JP2016502761A patent/JP6223543B2/en active Active
- 2014-03-14 MY MYPI2015702984A patent/MY192033A/en unknown
- 2014-03-14 KR KR1020197034502A patent/KR102153457B1/en active IP Right Grant
- 2014-03-14 HU HUE14720386A patent/HUE038448T2/en unknown
-
2015
- 2015-09-07 PH PH12015501987A patent/PH12015501987A1/en unknown
- 2015-09-08 IL IL241307A patent/IL241307B/en active IP Right Grant
- 2015-09-15 ZA ZA2015/06834A patent/ZA201506834B/en unknown
- 2015-11-13 US US14/941,183 patent/US9492429B2/en active Active
-
2016
- 2016-05-06 HK HK16105192.7A patent/HK1217177A1/en unknown
- 2016-07-01 US US15/200,129 patent/US9895350B2/en active Active
- 2016-07-18 HK HK16108429.6A patent/HK1220369A1/en unknown
-
2017
- 2017-02-03 JP JP2017018832A patent/JP6461214B2/en active Active
-
2018
- 2018-02-16 US US15/932,334 patent/US10383846B2/en active Active
- 2018-03-22 JP JP2018054386A patent/JP6694908B2/en active Active
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2019
- 2019-07-02 US US16/460,252 patent/US10772867B2/en active Active
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2020
- 2020-04-20 JP JP2020074670A patent/JP7008988B2/en active Active
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