BR112015023153A2 - utilização de um composto e composto - Google Patents
utilização de um composto e compostoInfo
- Publication number
- BR112015023153A2 BR112015023153A2 BR112015023153A BR112015023153A BR112015023153A2 BR 112015023153 A2 BR112015023153 A2 BR 112015023153A2 BR 112015023153 A BR112015023153 A BR 112015023153A BR 112015023153 A BR112015023153 A BR 112015023153A BR 112015023153 A2 BR112015023153 A2 BR 112015023153A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- hyperhidrosis
- abstract
- skin
- hours
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 208000008454 Hyperhidrosis Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000037315 hyperhidrosis Effects 0.000 abstract 1
- 210000004243 sweat Anatomy 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798073P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/028332 WO2014144075A1 (en) | 2013-03-15 | 2014-03-14 | Anticholinergic glycopyrrolate esters for the treatment of hyperhidrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015023153A2 true BR112015023153A2 (pt) | 2017-07-18 |
Family
ID=50625156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015023153A BR112015023153A2 (pt) | 2013-03-15 | 2014-03-14 | utilização de um composto e composto |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US9220707B2 (enExample) |
| EP (1) | EP2968267B1 (enExample) |
| JP (4) | JP6223543B2 (enExample) |
| KR (4) | KR102241660B1 (enExample) |
| CN (2) | CN105050596A (enExample) |
| AU (1) | AU2014227923B2 (enExample) |
| BR (1) | BR112015023153A2 (enExample) |
| CA (1) | CA2904724C (enExample) |
| DK (1) | DK2968267T3 (enExample) |
| ES (1) | ES2673098T3 (enExample) |
| HK (1) | HK1217177A1 (enExample) |
| HU (1) | HUE038448T2 (enExample) |
| IL (1) | IL241307B (enExample) |
| MX (1) | MX363601B (enExample) |
| MY (1) | MY192033A (enExample) |
| PH (1) | PH12015501987A1 (enExample) |
| PL (1) | PL2968267T3 (enExample) |
| PT (1) | PT2968267T (enExample) |
| SG (1) | SG11201507602SA (enExample) |
| TR (1) | TR201808040T4 (enExample) |
| WO (1) | WO2014144075A1 (enExample) |
| ZA (1) | ZA201506834B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2968267T3 (en) * | 2013-03-15 | 2018-06-25 | Bodor Laboratories Inc | SOFT ANTICHOLINERGE ESTERS FOR TREATMENT OF HYPERHIDROSE |
| WO2015138700A1 (en) * | 2014-03-13 | 2015-09-17 | Bodor Laboratories, Inc. | Use of selected anticholinergic zwitterions |
| US20150259283A1 (en) | 2014-03-13 | 2015-09-17 | Brickell Biotech, Inc. | Formulation for soft anticholinergic analogs |
| CN107427582B (zh) * | 2015-04-30 | 2021-03-05 | 久光制药株式会社 | 多汗症治疗用外用剂 |
| KR20180030893A (ko) | 2015-07-21 | 2018-03-26 | 보도르 라보래토리즈, 인크. | 연성 항콜린제 유사체를 위한 제제 |
| US20180235869A1 (en) * | 2015-09-11 | 2018-08-23 | Bodor Laboratories, Inc. | Methods and compositions for soft anticholinergic zwitterions |
| CN118021770A (zh) * | 2015-09-11 | 2024-05-14 | 博多尔实验仪器公司 | 软性抗胆碱能酯的方法和组合物 |
| CA3029621A1 (en) * | 2016-07-01 | 2018-01-04 | Bodor Laboratories, Inc. | Compositions and methods for treatment of copd |
| TWI719046B (zh) * | 2016-07-21 | 2021-02-21 | 美商波德實驗股份有限公司 | 軟性抗膽鹼類似物之製劑 |
| KR101951021B1 (ko) | 2017-02-06 | 2019-02-22 | 주식회사 퍼슨 | 발한억제 기능을 가지는 자외선 차단 화장료 조성물 및 이를 사용한 자외선 차단제의 제조방법 |
| DK3431072T3 (da) * | 2017-07-17 | 2020-02-17 | Dr August Wolff Gmbh & Co Kg Arzneimittel | Olie-i-vand-emulsion |
| WO2020020879A1 (en) | 2018-07-24 | 2020-01-30 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Topical emulsion of an anticholinergic compound |
| SG10201912063PA (en) * | 2019-12-12 | 2021-07-29 | Nat Skin Centre Singapore Pte Ltd | A pharmaceutical formulation |
| CA3174550A1 (en) | 2020-03-03 | 2021-09-10 | Kaken Pharmaceutical Co., Ltd. | Medicament containing sofpironium bromide |
| TW202146010A (zh) | 2020-03-03 | 2021-12-16 | 日商科研製藥股份有限公司 | 原發性腋窩多汗症的治療方法及其醫藥 |
| KR20250006082A (ko) | 2022-04-14 | 2025-01-10 | 독토르. 아우구스트 볼프 게엠베하 운트 코. 카게 아르쯔네이미텔 | 중증 다한증 및 과도 발한을 치료하기 위한 항콜린성 화합물의 국소 제형 |
| EP4260852A1 (en) | 2022-04-14 | 2023-10-18 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Topical formulation of an anticholinergic compound for treating severe hyperhidrosis and excessive sweating |
| KR102611847B1 (ko) * | 2023-03-27 | 2023-12-12 | 주식회사 이플라스크 | 무스카린 수용체 길항 활성을 갖는 신규한 피롤리디늄 화합물 및 이의 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292530A (en) | 1991-06-02 | 1994-03-08 | Helene Curtis, Inc. | Stable anhydrous topically-active composition and suspending agent therefor |
| EP1438001A4 (en) | 2001-09-26 | 2006-03-15 | Alison B Lukacsko | COMPOSITIONS AND METHODS FOR INHIBITING ECCRINS PERSPIRATION IN HUMANS |
| US8252316B2 (en) | 2002-05-03 | 2012-08-28 | Purepharm Inc. | Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating |
| GB0428416D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| GB0428418D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
| EP1948596B1 (en) | 2005-11-10 | 2011-10-19 | Nicholas S. Bodor | Soft anticholinergic esters |
| US7417147B2 (en) | 2005-11-10 | 2008-08-26 | Bodor Nicholas S | Soft anticholinergic zwitterions |
| US8071693B2 (en) | 2006-06-22 | 2011-12-06 | Sabic Innovative Plastics Ip B.V. | Polysiloxane/polyimide copolymers and blends thereof |
| EP2200550B1 (en) | 2007-10-18 | 2018-04-18 | Rose U, LLC | Topical glycopyrrolate formulations |
| DK2968267T3 (en) * | 2013-03-15 | 2018-06-25 | Bodor Laboratories Inc | SOFT ANTICHOLINERGE ESTERS FOR TREATMENT OF HYPERHIDROSE |
-
2014
- 2014-03-14 DK DK14720386.3T patent/DK2968267T3/en active
- 2014-03-14 HU HUE14720386A patent/HUE038448T2/hu unknown
- 2014-03-14 KR KR1020207015539A patent/KR102241660B1/ko active Active
- 2014-03-14 CN CN201480015677.0A patent/CN105050596A/zh active Pending
- 2014-03-14 KR KR1020217010876A patent/KR20210043742A/ko not_active Ceased
- 2014-03-14 MX MX2015012072A patent/MX363601B/es unknown
- 2014-03-14 KR KR1020197034502A patent/KR102153457B1/ko active Active
- 2014-03-14 PT PT147203863T patent/PT2968267T/pt unknown
- 2014-03-14 AU AU2014227923A patent/AU2014227923B2/en active Active
- 2014-03-14 TR TR2018/08040T patent/TR201808040T4/tr unknown
- 2014-03-14 US US14/213,242 patent/US9220707B2/en active Active
- 2014-03-14 SG SG11201507602SA patent/SG11201507602SA/en unknown
- 2014-03-14 KR KR1020157028470A patent/KR102050299B1/ko active Active
- 2014-03-14 PL PL14720386T patent/PL2968267T3/pl unknown
- 2014-03-14 ES ES14720386.3T patent/ES2673098T3/es active Active
- 2014-03-14 JP JP2016502761A patent/JP6223543B2/ja active Active
- 2014-03-14 HK HK16105192.7A patent/HK1217177A1/zh unknown
- 2014-03-14 CA CA2904724A patent/CA2904724C/en active Active
- 2014-03-14 BR BR112015023153A patent/BR112015023153A2/pt not_active Application Discontinuation
- 2014-03-14 WO PCT/US2014/028332 patent/WO2014144075A1/en not_active Ceased
- 2014-03-14 CN CN201811323473.XA patent/CN109364066A/zh active Pending
- 2014-03-14 EP EP14720386.3A patent/EP2968267B1/en active Active
- 2014-03-14 MY MYPI2015702984A patent/MY192033A/en unknown
-
2015
- 2015-09-07 PH PH12015501987A patent/PH12015501987A1/en unknown
- 2015-09-08 IL IL241307A patent/IL241307B/en active IP Right Grant
- 2015-09-15 ZA ZA2015/06834A patent/ZA201506834B/en unknown
- 2015-11-13 US US14/941,183 patent/US9492429B2/en active Active
-
2016
- 2016-07-01 US US15/200,129 patent/US9895350B2/en active Active
-
2017
- 2017-02-03 JP JP2017018832A patent/JP6461214B2/ja active Active
-
2018
- 2018-02-16 US US15/932,334 patent/US10383846B2/en active Active
- 2018-03-22 JP JP2018054386A patent/JP6694908B2/ja active Active
-
2019
- 2019-07-02 US US16/460,252 patent/US10772867B2/en active Active
-
2020
- 2020-04-20 JP JP2020074670A patent/JP7008988B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |