KR102197478B1 - 식도암을 검출 및 치료하기 위한 조성물 및 방법 - Google Patents

식도암을 검출 및 치료하기 위한 조성물 및 방법 Download PDF

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KR102197478B1
KR102197478B1 KR1020187020013A KR20187020013A KR102197478B1 KR 102197478 B1 KR102197478 B1 KR 102197478B1 KR 1020187020013 A KR1020187020013 A KR 1020187020013A KR 20187020013 A KR20187020013 A KR 20187020013A KR 102197478 B1 KR102197478 B1 KR 102197478B1
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cdr
antibody
progastrin
preferentially
seq
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KR20180108586A (ko
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알렉산더 프뢰르
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프로가스트린 에 캔서스 에스.에이 알.엘.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
    • G01N33/57407—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G01N33/57488—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Food Science & Technology (AREA)
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  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020187020013A 2015-12-31 2017-01-02 식도암을 검출 및 치료하기 위한 조성물 및 방법 Active KR102197478B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020207037405A KR102430893B1 (ko) 2015-12-31 2017-01-02 식도암을 검출 및 치료하기 위한 조성물 및 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15307189 2015-12-31
EP15307189.9 2015-12-31
EP16305139 2016-02-05
EP16305139.4 2016-02-05
PCT/EP2017/050037 WO2017114976A1 (en) 2015-12-31 2017-01-02 Compositions and methods for detecting and treating esophageal cancer

Related Child Applications (1)

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KR20180108586A KR20180108586A (ko) 2018-10-04
KR102197478B1 true KR102197478B1 (ko) 2021-01-04

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KR1020207037405A Active KR102430893B1 (ko) 2015-12-31 2017-01-02 식도암을 검출 및 치료하기 위한 조성물 및 방법

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US (2) US11789021B2 (https=)
EP (2) EP3397967B1 (https=)
JP (2) JP7018885B2 (https=)
KR (2) KR102197478B1 (https=)
CN (1) CN108700589A (https=)
AU (2) AU2017204686B2 (https=)
BR (1) BR112018013272A2 (https=)
CA (2) CA3193481A1 (https=)
EA (1) EA037032B1 (https=)
ES (2) ES3003287T3 (https=)
PL (1) PL3397967T3 (https=)
SG (1) SG11201805263TA (https=)
WO (1) WO2017114976A1 (https=)
ZA (1) ZA201804142B (https=)

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US20240018264A1 (en) * 2015-12-31 2024-01-18 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating ovarian cancer
WO2019110662A1 (en) * 2017-12-05 2019-06-13 Progastrine Et Cancers S.À R.L. Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
EP3759492A1 (en) 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
JP7449640B2 (ja) * 2018-03-13 2024-03-14 クレアティブ マイクロテック インコーポレイテッド 循環細胞を用いて被検者における治療反応及び疾患の進行をモニターする方法
KR102167078B1 (ko) * 2019-07-19 2020-10-16 (주)파즈코리아 혈액 샘플 이송 장치
WO2021081498A1 (en) * 2019-10-24 2021-04-29 The Johns Hopkins University Compositions and methods for detecting and treating esophageal cancer
JP7287532B2 (ja) * 2020-08-04 2023-06-06 王子ホールディングス株式会社 トイレットロール

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WO2011083091A2 (en) 2010-01-08 2011-07-14 Bioréalités S.A.S. Methods for treating pancreatic cancer

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WO2011083091A2 (en) 2010-01-08 2011-07-14 Bioréalités S.A.S. Methods for treating pancreatic cancer

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Publication number Publication date
AU2017204686A1 (en) 2018-07-05
AU2017204686B2 (en) 2020-04-30
JP2019505785A (ja) 2019-02-28
JP7363007B2 (ja) 2023-10-18
US11789021B2 (en) 2023-10-17
BR112018013272A2 (en) 2018-12-11
KR102430893B1 (ko) 2022-08-09
CA3009785A1 (en) 2017-07-06
PL3397967T3 (pl) 2021-06-28
KR20210002363A (ko) 2021-01-07
EA037032B1 (ru) 2021-01-28
WO2017114976A1 (en) 2017-07-06
US20240085423A1 (en) 2024-03-14
CA3193481A1 (en) 2017-07-06
KR20180108586A (ko) 2018-10-04
ZA201804142B (en) 2019-11-27
AU2020202296A1 (en) 2020-04-23
EP3397967A1 (en) 2018-11-07
AU2020202296B2 (en) 2022-06-02
JP7018885B2 (ja) 2022-02-14
CN108700589A (zh) 2018-10-23
EP3848709A1 (en) 2021-07-14
US20190011447A1 (en) 2019-01-10
EP3397967B1 (en) 2020-12-30
EP3848709B1 (en) 2024-12-04
EP3848709C0 (en) 2024-12-04
ES3003287T3 (en) 2025-03-10
ES2861587T3 (es) 2021-10-06
EA201891527A1 (ru) 2019-01-31
SG11201805263TA (en) 2018-07-30
JP2022064969A (ja) 2022-04-26

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