KR102167324B1 - 백본-고리형 펩타이드와의 조합물 - Google Patents

백본-고리형 펩타이드와의 조합물 Download PDF

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Publication number
KR102167324B1
KR102167324B1 KR1020157005848A KR20157005848A KR102167324B1 KR 102167324 B1 KR102167324 B1 KR 102167324B1 KR 1020157005848 A KR1020157005848 A KR 1020157005848A KR 20157005848 A KR20157005848 A KR 20157005848A KR 102167324 B1 KR102167324 B1 KR 102167324B1
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South Korea
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pneumonia
infection
dab
wound
diseases
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Korean (ko)
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KR20150038612A (ko
Inventor
글렌 이. 데일
다니엘 오브레취트
프란세스카 버나디니
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폴리포 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
KR1020157005848A 2012-08-08 2013-08-07 백본-고리형 펩타이드와의 조합물 Active KR102167324B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12005744 2012-08-08
EP12005744.3 2012-08-08
PCT/EP2013/066530 WO2014023757A1 (en) 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide

Publications (2)

Publication Number Publication Date
KR20150038612A KR20150038612A (ko) 2015-04-08
KR102167324B1 true KR102167324B1 (ko) 2020-10-20

Family

ID=46796226

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157005848A Active KR102167324B1 (ko) 2012-08-08 2013-08-07 백본-고리형 펩타이드와의 조합물

Country Status (25)

Country Link
US (1) US9775877B2 (enExample)
EP (1) EP2882770B1 (enExample)
JP (2) JP6486270B2 (enExample)
KR (1) KR102167324B1 (enExample)
CN (1) CN104684925B (enExample)
AU (1) AU2013301567B2 (enExample)
BR (1) BR112015002727B1 (enExample)
CA (1) CA2879207C (enExample)
CY (1) CY1119308T1 (enExample)
DK (1) DK2882770T3 (enExample)
EA (1) EA030077B1 (enExample)
ES (1) ES2639165T3 (enExample)
HR (1) HRP20171299T1 (enExample)
HU (1) HUE035891T2 (enExample)
IL (1) IL236697B (enExample)
LT (1) LT2882770T (enExample)
MX (2) MX366997B (enExample)
NZ (1) NZ703729A (enExample)
PL (1) PL2882770T3 (enExample)
PT (1) PT2882770T (enExample)
RS (1) RS56249B1 (enExample)
SG (1) SG11201500216TA (enExample)
SI (1) SI2882770T1 (enExample)
WO (1) WO2014023757A1 (enExample)
ZA (1) ZA201500278B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE475667T1 (de) 2007-02-28 2010-08-15 Polyphor Ltd Templat-fixierte peptidomimetika
RS56249B1 (sr) * 2012-08-08 2017-11-30 Polyphor Ag Kombinacije sa ciklizovanom okosnicom peptida
WO2022106063A2 (en) * 2020-11-23 2022-05-27 Polyphor Ag Compositions of a beta-hairpin peptidomimetic and aerosol dosage forms thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523713A (ja) * 2006-01-16 2009-06-25 ポリファー リミテッド テンプレート固定ペプチド擬似体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2527339T3 (es) 2001-02-23 2015-01-23 Polyphor Ltd. Peptidomiméticos fijados a patrón con actividad antimicrobiana
WO2004018503A1 (en) 2002-08-20 2004-03-04 Polyphor Ltd. Template-fixed peptidomimetics with antibacterial activity
ATE475667T1 (de) * 2007-02-28 2010-08-15 Polyphor Ltd Templat-fixierte peptidomimetika
WO2010017273A2 (en) * 2008-08-06 2010-02-11 Wyeth Tigecycline formulations
RS56249B1 (sr) * 2012-08-08 2017-11-30 Polyphor Ag Kombinacije sa ciklizovanom okosnicom peptida

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523713A (ja) * 2006-01-16 2009-06-25 ポリファー リミテッド テンプレート固定ペプチド擬似体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Annals of Clinical & Laboratory Science, Vol. 41, No. 1, pp. 39-43(2011.)*

Also Published As

Publication number Publication date
CY1119308T1 (el) 2018-02-14
EP2882770B1 (en) 2017-05-31
ZA201500278B (en) 2016-01-27
BR112015002727A2 (pt) 2017-08-08
US9775877B2 (en) 2017-10-03
JP6486270B2 (ja) 2019-03-20
DK2882770T3 (en) 2017-09-18
CN104684925B (zh) 2021-11-30
NZ703729A (en) 2018-03-23
ES2639165T3 (es) 2017-10-25
JP2015524460A (ja) 2015-08-24
PT2882770T (pt) 2017-09-11
HK1207866A1 (en) 2016-02-12
KR20150038612A (ko) 2015-04-08
IL236697B (en) 2020-02-27
CA2879207A1 (en) 2014-02-13
CN104684925A (zh) 2015-06-03
EA030077B1 (ru) 2018-06-29
AU2013301567B2 (en) 2017-08-03
MX366997B (es) 2019-08-02
HUE035891T2 (en) 2018-05-28
WO2014023757A1 (en) 2014-02-13
PL2882770T3 (pl) 2018-01-31
BR112015002727B1 (pt) 2022-09-06
HRP20171299T1 (hr) 2017-10-20
SI2882770T1 (sl) 2017-10-30
EP2882770A1 (en) 2015-06-17
US20150216927A1 (en) 2015-08-06
SG11201500216TA (en) 2015-03-30
LT2882770T (lt) 2017-10-10
MX2019002657A (es) 2019-07-15
AU2013301567A1 (en) 2015-02-05
IL236697A0 (en) 2015-02-26
MX2015001685A (es) 2015-04-10
RS56249B1 (sr) 2017-11-30
JP2018087191A (ja) 2018-06-07
CA2879207C (en) 2021-02-16
EA201590351A1 (ru) 2016-05-31

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