AU2013301567B2 - Combinations with a backbone-cyclized peptide - Google Patents

Combinations with a backbone-cyclized peptide Download PDF

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Publication number
AU2013301567B2
AU2013301567B2 AU2013301567A AU2013301567A AU2013301567B2 AU 2013301567 B2 AU2013301567 B2 AU 2013301567B2 AU 2013301567 A AU2013301567 A AU 2013301567A AU 2013301567 A AU2013301567 A AU 2013301567A AU 2013301567 B2 AU2013301567 B2 AU 2013301567B2
Authority
AU
Australia
Prior art keywords
infection
animal
pseudomonas aeruginosa
human
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013301567A
Other languages
English (en)
Other versions
AU2013301567A1 (en
Inventor
Francesca BERNARDINI
Glenn E. Dale
Daniel Obrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spexis AG
Original Assignee
Polyphor AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyphor AG filed Critical Polyphor AG
Publication of AU2013301567A1 publication Critical patent/AU2013301567A1/en
Application granted granted Critical
Publication of AU2013301567B2 publication Critical patent/AU2013301567B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2013301567A 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide Ceased AU2013301567B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12005744.3 2012-08-08
EP12005744 2012-08-08
PCT/EP2013/066530 WO2014023757A1 (en) 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide

Publications (2)

Publication Number Publication Date
AU2013301567A1 AU2013301567A1 (en) 2015-02-05
AU2013301567B2 true AU2013301567B2 (en) 2017-08-03

Family

ID=46796226

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013301567A Ceased AU2013301567B2 (en) 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide

Country Status (25)

Country Link
US (1) US9775877B2 (enExample)
EP (1) EP2882770B1 (enExample)
JP (2) JP6486270B2 (enExample)
KR (1) KR102167324B1 (enExample)
CN (1) CN104684925B (enExample)
AU (1) AU2013301567B2 (enExample)
BR (1) BR112015002727B1 (enExample)
CA (1) CA2879207C (enExample)
CY (1) CY1119308T1 (enExample)
DK (1) DK2882770T3 (enExample)
EA (1) EA030077B1 (enExample)
ES (1) ES2639165T3 (enExample)
HR (1) HRP20171299T1 (enExample)
HU (1) HUE035891T2 (enExample)
IL (1) IL236697B (enExample)
LT (1) LT2882770T (enExample)
MX (2) MX366997B (enExample)
NZ (1) NZ703729A (enExample)
PL (1) PL2882770T3 (enExample)
PT (1) PT2882770T (enExample)
RS (1) RS56249B1 (enExample)
SG (1) SG11201500216TA (enExample)
SI (1) SI2882770T1 (enExample)
WO (1) WO2014023757A1 (enExample)
ZA (1) ZA201500278B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009008843A (es) 2007-02-28 2009-08-28 Polyphor Ltd Peptidomimeticos fijados a un patron.
ES2639165T3 (es) * 2012-08-08 2017-10-25 Polyphor Ag Combinaciones con un péptido de esqueleto ciclado
KR20230123950A (ko) * 2020-11-23 2023-08-24 스펙시스 아게 베타-헤어핀 펩티도미메틱의 조성물 및 이의 에어로졸 투여 형태
CN116782879A (zh) * 2020-11-23 2023-09-19 斯佩希斯股份公司 β-发夹素拟肽的组合物及其气雾剂剂型

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007079597A1 (en) * 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7253146B2 (en) 2001-02-23 2007-08-07 Polyphor Ltd Template-fixed peptidomimetics with antimicrobial activity
AU2002342618C1 (en) 2002-08-20 2008-10-30 Polyphor Ltd. Template-fixed peptidomimetics with antibacterial activity
MX2009008843A (es) * 2007-02-28 2009-08-28 Polyphor Ltd Peptidomimeticos fijados a un patron.
WO2010017273A2 (en) * 2008-08-06 2010-02-11 Wyeth Tigecycline formulations
ES2639165T3 (es) * 2012-08-08 2017-10-25 Polyphor Ag Combinaciones con un péptido de esqueleto ciclado

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007079597A1 (en) * 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity

Also Published As

Publication number Publication date
RS56249B1 (sr) 2017-11-30
BR112015002727A2 (pt) 2017-08-08
LT2882770T (lt) 2017-10-10
KR20150038612A (ko) 2015-04-08
EA030077B1 (ru) 2018-06-29
MX2019002657A (es) 2019-07-15
CY1119308T1 (el) 2018-02-14
JP2015524460A (ja) 2015-08-24
JP6486270B2 (ja) 2019-03-20
ES2639165T3 (es) 2017-10-25
HRP20171299T1 (hr) 2017-10-20
CA2879207C (en) 2021-02-16
AU2013301567A1 (en) 2015-02-05
EP2882770A1 (en) 2015-06-17
PT2882770T (pt) 2017-09-11
BR112015002727B1 (pt) 2022-09-06
MX366997B (es) 2019-08-02
US20150216927A1 (en) 2015-08-06
EP2882770B1 (en) 2017-05-31
IL236697B (en) 2020-02-27
HK1207866A1 (en) 2016-02-12
SG11201500216TA (en) 2015-03-30
JP2018087191A (ja) 2018-06-07
CN104684925A (zh) 2015-06-03
ZA201500278B (en) 2016-01-27
IL236697A0 (en) 2015-02-26
KR102167324B1 (ko) 2020-10-20
DK2882770T3 (en) 2017-09-18
MX2015001685A (es) 2015-04-10
WO2014023757A1 (en) 2014-02-13
US9775877B2 (en) 2017-10-03
CA2879207A1 (en) 2014-02-13
CN104684925B (zh) 2021-11-30
HUE035891T2 (en) 2018-05-28
EA201590351A1 (ru) 2016-05-31
PL2882770T3 (pl) 2018-01-31
SI2882770T1 (sl) 2017-10-30
NZ703729A (en) 2018-03-23

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired