KR102143252B1 - 지혈 조성물 - Google Patents

지혈 조성물 Download PDF

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Publication number
KR102143252B1
KR102143252B1 KR1020147012291A KR20147012291A KR102143252B1 KR 102143252 B1 KR102143252 B1 KR 102143252B1 KR 1020147012291 A KR1020147012291 A KR 1020147012291A KR 20147012291 A KR20147012291 A KR 20147012291A KR 102143252 B1 KR102143252 B1 KR 102143252B1
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KR
South Korea
Prior art keywords
hemostatic composition
crosslinking agent
hemostatic
hydrophilic
polymer
Prior art date
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Application number
KR1020147012291A
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English (en)
Korean (ko)
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KR20140074993A (ko
Inventor
한스 크리스티안 헤드리히
요리스 회핑호프
Original Assignee
백스터 인터내셔널 인코포레이티드
박스터 헬쓰케어 에스에이
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Publication of KR20140074993A publication Critical patent/KR20140074993A/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A61K38/015—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen from keratin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147012291A 2011-10-11 2012-10-10 지혈 조성물 Active KR102143252B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161545939P 2011-10-11 2011-10-11
US61/545,939 2011-10-11
PCT/EP2012/070054 WO2013053753A2 (en) 2011-10-11 2012-10-10 Hemostatic composition

Publications (2)

Publication Number Publication Date
KR20140074993A KR20140074993A (ko) 2014-06-18
KR102143252B1 true KR102143252B1 (ko) 2020-08-11

Family

ID=47022655

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147012291A Active KR102143252B1 (ko) 2011-10-11 2012-10-10 지혈 조성물

Country Status (11)

Country Link
US (1) US20130096062A1 (enExample)
EP (2) EP4137166A1 (enExample)
JP (2) JP6195567B2 (enExample)
KR (1) KR102143252B1 (enExample)
CN (1) CN103998068B (enExample)
AU (1) AU2012318256B2 (enExample)
CA (1) CA2851332C (enExample)
ES (1) ES2938541T3 (enExample)
IL (1) IL231962A0 (enExample)
MX (1) MX355924B (enExample)
WO (1) WO2013053753A2 (enExample)

Families Citing this family (26)

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US8642831B2 (en) 2008-02-29 2014-02-04 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
EP2766058B1 (en) 2011-10-11 2022-11-23 Baxter International Inc. Hemostatic compositions
ES2938568T3 (es) 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
CA2865349C (en) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
EP2825216B1 (en) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Dry haemostatic composition
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
RU2678592C1 (ru) 2013-12-11 2019-01-30 Ферросан Медикал Дивайсиз А/С Сухая композиция, содержащая компонент, улучшающий экструзию
RU2546006C1 (ru) 2014-03-07 2015-04-10 Римма Ильинична Ашкинази Противовирусное средство
KR102132261B1 (ko) 2014-03-31 2020-08-06 삼성전자주식회사 비교 연산이 필요없이 최종 모듈러 감소를 하는 몽고메리 곱셈 방법 및 곱셈기
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
BR112017013565B1 (pt) 2014-12-24 2021-12-28 Ferrosan Medical Devices A/S Seringa para retenção e mistura de primeira e segunda substâncias
WO2016118043A1 (ru) * 2015-01-20 2016-07-28 Виктор Вениаминович ТЕЦ Гемостатическое средство
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
RU2602305C1 (ru) * 2015-09-30 2016-11-20 Общество с ограниченной ответственностью "Санте Фарм" Гемостатическое средство
EP3630082A4 (en) 2017-05-24 2021-12-15 Viktor Veniaminovich Tets FRACTIONED ANTIMICROBIAL COMPOSITIONS AND THEIR USE
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
EP3717028A1 (en) * 2017-11-28 2020-10-07 Baxter International Inc Wound-treating absorbent
WO2019107887A2 (ko) * 2017-11-28 2019-06-06 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
US10786596B2 (en) * 2018-01-12 2020-09-29 Boston Scientific Scimed, Inc. Powder for achieving hemostasis
KR20210008479A (ko) 2018-05-09 2021-01-22 훼로산 메디칼 디바이스 에이/에스 지혈 조성물을 제조하는 방법
KR102438006B1 (ko) 2020-02-25 2022-08-30 주식회사 테라시온 바이오메디칼 다용도 지혈제 조성물 및 그 제조방법
WO2021261080A1 (ja) * 2020-06-26 2021-12-30 国立研究開発法人物質・材料研究機構 多孔体、封止材、穿刺部封止装置、止血シート、及び、多孔体の製造方法
JP2023539104A (ja) * 2020-08-18 2023-09-13 ウニヴェルズィテート バーゼル 止血性エラスチン様ポリペプチド
JP2022126909A (ja) * 2021-02-19 2022-08-31 国立研究開発法人物質・材料研究機構 穿孔部閉鎖材、及び、穿孔部閉鎖材の製造方法
CN113289052B (zh) * 2021-05-14 2023-05-26 南方科技大学 一种可控交联、降解的材料及其应用
CN113599568A (zh) * 2021-08-05 2021-11-05 南方科技大学 合成材料类粉剂及其在止血体系的应用

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ES2938568T3 (es) * 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
EP2766058B1 (en) * 2011-10-11 2022-11-23 Baxter International Inc. Hemostatic compositions

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
AU2012318256A1 (en) 2013-05-02
JP6195567B2 (ja) 2017-09-13
CA2851332A1 (en) 2013-04-18
WO2013053753A2 (en) 2013-04-18
EP2766060A2 (en) 2014-08-20
WO2013053753A3 (en) 2013-11-07
MX355924B (es) 2018-05-04
MX2014004476A (es) 2015-11-16
CN103998068A (zh) 2014-08-20
IL231962A0 (en) 2014-05-28
US20130096062A1 (en) 2013-04-18
JP2017153975A (ja) 2017-09-07
KR20140074993A (ko) 2014-06-18
CA2851332C (en) 2020-08-25
ES2938541T3 (es) 2023-04-12
CN103998068B (zh) 2016-05-25
AU2012318256B2 (en) 2015-10-01
EP4137166A1 (en) 2023-02-22
JP2014530066A (ja) 2014-11-17
EP2766060B1 (en) 2022-11-23

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