KR102085089B1 - Hot water extract of mixed medicinal herbs comprising Valeriana fauriei and beverage composition usign the same - Google Patents

Abstract

The present invention comprises 12 kinds of herbal medicines including Valerian, that is, hot water extracts of mixed herbal medicines including Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, ginger, control (jujube), Schisandra chinensis and lotus root Provides a beverage composition.
Hot water extract of the mixed herbal medicine containing Valerian of the present invention and the beverage composition using the same can be usefully used as a truly potent beverage composition in the field of the use of Valerian and herbal materials and beverage industry.

Description

Hot water extract of mixed medicinal herbs comprising Valeriana fauriei and beverage composition usign the same}

The present invention relates to a hydrothermal extract of a mixed herbal medicine, and more particularly, to a hydrothermal extract of a mixed herbal medicine containing Valerian herb and a beverage composition using the same.

Valerian fauriei is a perennial herb belonging to the Valerianaceae family, with about 200 species distributed throughout the world, mainly in the temperate regions of Europe and Asia in the northern hemisphere, and are referred to as heel, gilded, scented, green tea. Valerian quality is generally defined by the essential oil content rather than appearance. The content of valepotriate varies depending on the season, so its content is the highest in spring but the amount of water is the highest in autumn. It is supposed to be.

The predicate called Valeriana has been recorded since the 9th and 10th centuries in Europe, and the dried species was used as a herbal medicine called Valerian. The application of this formulation is based on the work done by the Anglo-Saxon family at the 11th time, which was used not only in medicine, but also as a special spice or spice. Pharmacologically, kessylglycol diacetate and kesoglycol-8-monoacetate prolong sleep, inhibit spontaneous behavior, passive avoidance, reaction inhibition, sedation and antistress gastric ulcers. There is action. According to previous theories, acetyl acetic acid has been known as a component of strong sedation, but since essential oils show only about one third of the sedation effects of roots, the presence of active ingredients other than essential oils is assumed in the roots. The alkaloids of Gilcho were also proven effective and paralyzed.

Pharmaceutical application to sedation, myrrh, other neurological disorders and simultaneous prescription with other sedatives. It is also known that it is widely used as a folk medicine even recently as a treatment for asthma. Western Gilcho has been transmitted as an antihysteric medicine, and in oriental medicine, it is applied to colic, menstrual irregularity, piercing, anti-acute treatment, nervous anxiety, hypertension and stomach pain. In addition, the roots of this plant have a unique scent and have been widely used in the production of tonic flavors, fragrances and tobacco flavors of liquor, which can increase the fragrance properties of leaf tobacco.

Valerian is currently distributed around the world for medicinal or fragrance applications. European valerian (Valeriana officinalis L.) is produced in Belgium, the Netherlands and Germany, and Indian valerian (Valeriana wallichii DC) is produced in India, Nepal and the Himalayas. ) And Japanese valerian (Valeriana fauriei Briq.) Produced in Japan, China, etc. The composition of essential oils varies according to species and production region, and is sold separately in the world perfume market. Essential oils obtained from Japanese Valerian are known as kesso oil, which has a higher essential oil content and a different composition than essential oils. It is not yet cultivated in Korea and is collected in small amounts by herbalists. However, domestic juveniles have more essential oils, vary in the composition of essential oils, and have many valepotriate compounds, which are the causative agents of efficacy, as they are more likely to be developed as medicinal and fragrance resources. Should be done.

According to the 2011 Research on Utilization and Utilization of Valerian fauriei Briquet Efficacy of Ginseng Specialty Research Institute, National Institute of Horticultural & Specialty Science, Rural Development Administration, Juvenile relied on imports of all herbs and extracts from China, Japan and Europe. The demand for antidepressant and psychotic drugs is steadily increasing, and related drugs are reported to be growing rapidly to the domestic market of anti-depressant drugs as the top 10 drugs in the world. In addition, in Europe and North America, it is developed and sold as a diet food, candy, gelatin, pudding, teas, tablets, powder, capsules, liquids, etc. by pharmaceutical companies of the world's multinational corporations using the ingredients of crude urine and crude extracts. Valale oil crude extract is very expensive. Valerian extract is one of the eight largest products in North America and one of Austria's top 10 products. Europe has a $ 200 million market, but there are no products available for processing of Valerian grass in Korea. The U.S. FDA has verified that the components of the extract of Valerian grass among the world's top 10 products are safe for the human body, and that Valerian grass imported from Korea is reported to be made by natural extraction.

Korea Patent Registration No. 10-1731216 (2017.04.21.) Korea Patent Registration No. 10-1827873 (2018.02.05.) Korea Patent Registration No. 10-0870139 (2008.11.18.) Korea Patent Registration No. 10-0465262 (2004.12.28.)

The inventors of the present invention while studying the technology to improve the unique flavor that was difficult to use as a food material in order to take advantage of the sedation efficacy (sleep disorder, stress improvement) of Valerian grass, while using a specific herbs and specific ratio When mixed and extracted, high hydrothermal extracts are obtained, and when the beverage composition is prepared by including the hydrothermal extract of the mixed medicinal herb in a specific ratio, it was confirmed that it is possible to develop a successful beverage composition by obtaining an excellent score in sensory evaluation. .

Therefore, an object of the present invention is to provide a hot water extract of the mixed herbal medicine containing Valerian grass and a beverage composition using the same.

According to an aspect of the present invention, a hydrothermal extract of a mixed herbal medicine including Valerian, Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, Ginger, Control (jujube), Schisandra chinensis and Yeonjak is provided.

In one embodiment, the hydrothermal extract of the mixed herbal medicine is 3 to 5% by weight, Valerian 9 to 11% by weight, ginseng 5 to 7% by weight, Angelica 7 to 9% by weight, Bokyeong 7 to about the total weight of the mixed herbal medicine 9 weight percent and control 7-9 weight percent.

In one embodiment, the hydrothermal extract of the mixed herbal medicine is 3 to 5% by weight, Valerian 9 to 11% by weight, ginseng 5 to 7% by weight, Astragalus 9 to 11% by weight, Angelica 7 ~ to the total weight of the mixed herbal medicine 9 wt%, licorice 5-7 wt%, Fuling 7-9 wt%, Sanjoin 9-11 wt%, Longan meat 9-11 wt%, Ginger 5-7 wt%, Control 7-9 wt%, Schizandra 5-7 It may comprise 9% by weight and 9-11% by weight soft meat.

In one embodiment, the hydrothermal extract is characterized in that it has a sedative action.

According to another aspect of the present invention, there is provided a beverage composition comprising the hot water extract of the mixed herbal medicine.

In one embodiment, the beverage composition may include 15 to 25% by weight of the hydrothermal extract and 7.5 to 15% by weight of fructooligosaccharide based on the total weight of the beverage composition.

According to the present invention, 12 kinds of herbal medicines including Valerian, that is, hot water extract of mixed herbal medicines including Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, ginger, control (jujube), Schisandra chinensis and lotus root In the sensory evaluation, it was found that when the beverage composition was prepared by including the hot water extract of the mixed herbal medicine in a specific ratio, the sensory evaluation was able to develop a successful beverage composition.

Therefore, the hot water extract of the mixed herbal medicine containing Valerian of the present invention and a beverage composition using the same can be usefully used as a truly potent beverage composition in the field of the use of Valerian and herbal materials and beverage industry.

Figure 1 is a photograph showing a beverage sample (A) and the manufacturing process (B) using Valerian and herbal extracts.
2 is a photograph of laboratory researchers performing sensory evaluation of beverages using Valerian grass and herbal materials.
3 is a photograph showing a beverage concentrate preparation process.
Figure 4 is a photograph showing the prototype production process for deriving a healthy beverage compounding ratio using Valerian grass and herbal materials.
Figure 5 is a photograph of laboratory researchers performing sensory evaluation of the health beverage prototype using Valerian grass and herbal materials.
6 is a sensory evaluation result of the prototype using Valerian grass and herbal materials.

The present invention provides a hydrothermal extract of mixed herbal medicines including Valerian, Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, Ginger, Control (jujube), Schisandra chinensis and lotus root.

Valerian grass is used as a herbal material in Korea, but it has been difficult to use as a food ingredient because of its unique smell. In Europe and other countries, it is widely used as a health functional food for sleep disorders, but in Korea, it only relies on imports of overseas products, and oriental materials also rely only on imports from China. In order to replace imported raw materials and products by increasing the use of domestic Valerian grass through this project, Jane Welllife Co., Ltd. developed and commercialized beverages using domestic Valerian grass and herbal materials, and jointed it with Jungwon University The purpose of this study is to examine the efficacy of anti-settling (sleeping disorder, stress improvement) efficacy of beverage using herbal and herbal materials through scientific data. Based on objective and scientific efficacy data, we will develop and commercialize beverage products with anti-sedative (sleep disorder, stress improvement) efficacy using domestic juvenile urine and herbal ingredients.

It is believed that it was caused by the divine spirit of the pine tree soaking in the ground because it is marked as old spirit in the old literature. Therefore, there is a record that if you carry a fist-sized ghost, you will defeat all ghosts and disasters. The ghost of the pine tree is made up of the pine tree, which is pulled out and gathered out to form the name of the spirit in the meaning of the rest of the spirits (零) .If the pine's essence is not strong, it forms around the tree roots and surrounds the roots without falling from the roots. It is said to be called the deity. This medicine is sweet and tasteless and has a flat and flat nature. Fuxin is used for heart palpitations, forgetfulness and oil wells due to nervousness and swelling of the abdomen and the whole body. Pharmacological actions include diuresis, fungi, intestinal relaxation, ulcer prevention, hypoglycemic activity, increased cardiac contractility, immunopotentiation, and antitumor activity.

Sanjoin is used for nervousness, insomnia, forgetfulness, and cold sweating. It also strengthens the stomach and is effective for anemia. Pharmacological action, sedation, hypnosis, lowering blood pressure, analgesic, lowering body temperature, antioxidant activity, immune hyperactivity, uterine excitement, burn edema suppression. Appearance is oval, outer surface is yellowish brown or reddish brown, smooth and glossy. On one side there is a point, on the other side there is a point, and the barges are around one side of the point along the margin. Seed husks are slightly pliable and cover gray oil and light yellow cotyledons.

Schisandra chinensis is the fruit of Schisandra chinensis, a deciduous vine of the Magnoliaceae family, and has the functions of pterosaurs, astringents, and Ningxianxins. It is a valuable herb that is balanced against. Already, Schisandra chinensis extract proved to be truly hypnotic in rat experiments.

Nelumbo nucifera is a ripe seed of lotus belonging to the water lily family in autumn and dried by removing the rind. It is effective for insomnia with the effects of bodhisattva, iris fixation, and constipation. 10-13) have been reported, and recently, the identification and isolation of the plant hormone clihydrophaseic acid, its effect on mutagenicity and the fact that it is rich in amino acids serine and methionine (14,15) and treatment for depression And report 16). As described above, some herbal materials that can be used as foods in Guibi-tang, a prescription widely used for entanglement, fatigue, anorexia, palpitations, including tension and insomnia caused by physical and mental overwork or great shock. , Astragalus, Angelica, Licorice, Bokryeong, Sanjoincho, Longan, ginger, jujube) was applied.

In one embodiment, the hydrothermal extract of the mixed herbal medicine is 3 to 5% by weight, Valerian 9 to 11% by weight, ginseng 5 to 7% by weight, Angelica 7 to 9% by weight, Bokyeong 7 to about the total weight of the mixed herbal medicine 9 weight percent and control 7-9 weight percent.

In one embodiment, the hydrothermal extract of the mixed herbal medicine is 3 to 5% by weight, Valerian 9 to 11% by weight, ginseng 5 to 7% by weight, Astragalus 9 to 11% by weight, Angelica 7 ~ to the total weight of the mixed herbal medicine 9 wt%, licorice 5-7 wt%, Fuling 7-9 wt%, Sanjoin 9-11 wt%, Longan meat 9-11 wt%, Ginger 5-7 wt%, Control 7-9 wt%, Schizandra 5-7 It may comprise 9% by weight and 9-11% by weight soft meat.

The hydrothermal extract of the mixed medicinal herb quantitatively quantitatively quantitatively formulated with Valerian, Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Yong'an, Ginger, Control (jujube), Schisandra chinensis and lotus root After mixing with purified water, during the extraction time of the active ingredient at a hot water extraction temperature, for example, 98 ~ 100 ℃, for example, about 3 to 4 hours after extraction, it can be used as a beverage raw material through a stagnation for about 6 hours.

In one embodiment, the hydrothermal extract is characterized in that it has a sedative action.

In addition, the present invention provides a beverage composition comprising the hydrothermal extract of the mixed herbal medicine.

In one embodiment, the beverage composition may include 15 to 25% by weight of the hydrothermal extract and 7.5 to 15% by weight of fructooligosaccharide based on the total weight of the beverage composition.

The hydrothermal extracts of mixed herbal medicines including 12 kinds of herbal medicines of the present invention, namely Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokyeong, Sanjoin, Longan meat, ginger, control (jujube), Schisandra chinensis and lotus root Receive high evaluation in the case of preparing a beverage composition containing the hydrothermal extract of the mixed herbal medicine in a specific ratio to obtain excellent score in sensory evaluation can be developed into a successful beverage composition.

Hereinafter, the present invention will be described in more detail with reference to Examples. However, the following examples are intended to illustrate the present invention, but the scope of the present invention is not limited thereto.

<Example>

1. Exploring Herbal Materials with Anti-Soothing Effects

12 kinds of herbal materials including juvenile, etc. were selected as potent herbal ingredients by selecting Valerian, Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, Ginger, Control (jujube), Schisandra chinensis and Yeonja meat. .

2. Examination of food availability of 12 kinds of Valerian and Oriental medicine

A review of the Food and Drug Administration's Food Ingredients confirmed that Valerian and 12 kinds of herbal medicines could be used or limited as food. Valerian, Baekchul, Bokryeong, and Yeonjak were limitedly available, but it was confirmed that the general use of these herbal ingredients can be used as food ingredients as a whole.

3. Development of Drink Mixing Ratio Using Valerian Herb Extract

In order to develop a healthy drink with excellent soothing efficacy and palatability, a beverage sample was prepared by setting a blending ratio as shown in Table 1 below, and the final blending ratio was derived through sensory evaluation of the prepared beverage sample (see FIG. 1).

end. Drink mix ratio using Valerian grass and herbal materials

Table 1 shows the beverage blending ratio (wt%) using Valerian and herbal materials.

JW-V-01 JW-V-02 JW-V-03 JW-V-04 JW-V-05 Valerian 0.00 1.93 3.93 3.93 5.93 Whiteness 9.80 9.80 9.80 7.80 9.80 Ginseng 9.81 7.88 5.88 11.88 5.88 Astragalus 9.80 9.80 9.80 9.80 9.80 Donkey 7.85 7.85 7.85 5.85 5.85 licorice 5.88 5.88 5.88 5.88 5.88 Ghost 7.85 7.85 7.85 5.85 7.85 Sanjoin 9.80 9.80 9.80 9.80 9.80 Dragon meat 9.80 9.80 9.80 9.80 9.80 ginger 5.88 5.88 5.88 5.88 5.88 contrast 7.85 7.85 7.85 7.85 7.85 Schisandra 5.88 5.88 5.88 5.88 5.88 Lotus root 9.80 9.80 9.80 9.80 9.80 Sum 100.00 100.00 100.00 100.00 100.00

Herbal ingredients for each sample were quantified and then blended sequentially. After mixing with 5,800 ~ 6,000 ml of purified water and extracted for 3-4 hours at 98 ~ 100 ℃. After 6 hours after the plateau was used as a beverage sample.

The beverage samples prepared according to the respective mixing conditions were subjected to sensory evaluation at the laboratory level, and the most favorable compounding ratio was selected as the final product sample.

I. Sensory Evaluation of Drinks Using Valerian and Herbal Materials

Sensory evaluation of beverages using Valerian and herbal materials was carried out by laboratory researchers, and evaluated by a 5-point scale method (see FIG. 2).

The grading criteria were very bad (1), bad (2), moderate (3), good (4) and very good (5). The test items were color, taste and mouthfeel. Sense in mouth, Flavor, and Overall over all were evaluated.

All. Sensory Evaluation of Drinks Using Valerian and Herbal Materials

The grading criteria were very bad (1), bad (2), moderate (3), good (4), and very good (5). The test items were color, intensity of taste, and mouthfeel. (sense in mouth), flavor (flavor) and overall preference (perference over all) to evaluate the results are shown in Table 2 below.

sample color flavor Texture incense Overall preference JW-V-01 3,40 ± 0.45 3.30 ± 0.78 3.60 ± 0.73 3.60 ± 0.48 3.70 ± 0.64 JW-V-02 3.50 ± 0.74 3.60 ± 0.96 3.80 ± 0.40 3.40 ± 0.66 3.90 ± 0.76 JW-V-03 3.70 ± 0.78 3.80 ± 0.67 3.90 ± 0.70 3.60 ± 0.66 3.90 ± 0.62 JW-V-04 3.40 ± 0.66 3.20 ± 0.60 3.50 ± 0.74 3.60 ± 0.48 3.60 ± 0.48 JW-V-05 3.40 ± 0.58 3.50 ± 0.59 3.40 ± 0.58 3.70 ± 0.55 3.50 ± 0.50

Sensory evaluation results for five beverage samples The highest evaluation results for sample JW-V-03 were 3.70 ± 0.78, 3.80 ± 0.67, 3.90 ± 0.70, 3.60 ± 0.48 and 3.90 ± 0.62, respectively, for color, taste, texture, aroma and overall acceptability. Showed.

la. Plant Concentrate Preparation Using Valerian Herb and Herbal Materials

The beverage concentrate preparation process is shown in FIG. 3. After inspecting food code and compliance, the raw materials were washed and put into the extraction tank. The raw materials were placed in an extractor and mixed with the extract of Valerian extract extracted with alcohol by adding 6-8 times of water, followed by extraction at 90 ° C.-95 ° C. for 12 hours, followed by filtration with a 25 micron filter. The filtrate was concentrated under reduced pressure to make a concentrate so as to have a solid content of 60% or more (65 Brix or more), and the resulting concentrate was sterilized at 90 ° C. for 30 minutes and then packaged according to the packing method.

4. Prototype of healthy beverages using Valerian grass and herbal materials

end. Development of Prototype Ratio of Healthy Beverage Prototype Using Valerian Herb Herb

Concentrated liquids were prepared at the ratio of health drink used in the first sensory evaluation, and food additives were added to produce prototypes. In addition, to develop a prototype with excellent soothing efficacy and palatability, a sample was prepared by setting a blending ratio, and a final blending ratio was derived through sensory evaluation of the prepared sample.

The health beverage prototype blending ratio (wt%) using Valerian and herbal materials is shown in Table 3 below.

HBS-01 HBS-02 HBS-03 HBS-04 HBS-05 Valerian Plant Concentrate 10 20 30 20 20 Fructooligosaccharide 10 10 10 5 0 Jujube concentrate 0 0 0 5 0 Pear Concentrate 0 0 0 0 10 Vitamin Mineral Mix FS1 0.2 0.2 0.2 0.2 0.2 mortgage 20 20 20 20 20 Purified water 59.8 49.8 39.8 49.8 49.8 Sum 100.00 100.00 100.00 100.00 100.00

I. Prototype production for derivation of health drink mix ratio using jujube and herbal materials

4 shows a prototype manufacturing process for deriving a healthy beverage compounding ratio using Valerian grass and herbal materials.

All. Sensory Evaluation of Healthy Beverage Prototypes Using Valerian and Herbal Materials

Prototype samples prepared according to the respective mixing conditions were selected by randomly selected personnel in the Goesan group, and sensory evaluation was performed to select the most favorable compounding ratio as the final prototype, and evaluated by the 5-point scale method (see FIG. 5). .

The grading criteria were very bad (1), bad (2), moderate (3), good (4) and very good (5). The test items were color, taste and mouthfeel. Sense in mouth, Flavor, and Overall over all were evaluated.

la. Sensory Evaluation of Prototypes Using Valerian and Herbal Materials

The grading criteria were very bad (1), bad (2), moderate (3), good (4), and very good (5). The test items were color, intensity of taste, and mouthfeel. (sense in mouth), flavor (flavor) and overall preference (perference over all) was evaluated, the results are shown in Figure 6 and Table 4 below.

sample color flavor Texture incense Overall preference HBS-01 3.40 ± 0.48 3.70 ± 0.45 4.20 ± 0.40 3.50 ± 0.50 3.70 ± 0.21 HBS-02 4.00 ± 0.77 3.70 ± 0.45 4.00 ± 0.44 4.00 ± 0.77 3.92 ± 0.35 HBS-03 3.70 ± 0.64 4.00 ± 0.44 3.80 ± 0.60 3.70 ± 0.45 3.80 ± 0.29 HBS-04 3.80 ± 0.60 3.80 ± 0.40 3.80 ± 0.60 3.50 ± 0.50 3.72 ± 0.23 HBS-05 3.90 ± 0.83 3.60 ± 0.66 3.50 ± 0.50 3.60 ± 0.48 3.65 ± 0.33

hemp. Review of Sensory Evaluation of Prototype Using Valerian Grass and Herbal Materials

Sensory evaluation of the five beverage samples showed that HBS-02 had the highest ratings of 4.00 ± 0.77, 3.70 ± 0.45, 4.00 ± 0.44, 4.00 ± 0.77 and 3.92 ± 0.35 to color, taste, texture, aroma and overall preference. . Samples containing jujube concentrate and pear concentrate did not show good results due to the impaired taste of the product, and the amount of Valerian plant mixture concentrate showed that 20% was most appropriate.

Claims (6)

Valerian, Baekchul, Ginseng, Astragalus, Angelica, Licorice, Bokryeong, Sanjoin, Longan meat, Ginger, Contrast (jujube), Schizandra chinensis and lotus root, 3 ~ 5% by weight based on the total weight of mixed herbal medicine, Baekwoo 9 ~ 11 wt%, Ginseng 5-7 wt%, Astragalus 9-11 wt%, Angelica 7-9 wt%, Licorice 5-7 wt%, Bokryeong 7-9 wt%, Sanjoin 9-11 wt%, Longan 9-11 Hot water extract of the mixed herbal medicine with improved urinal flavour, characterized in that it comprises 5% by weight, ginger 5-7% by weight, control 7-9% by weight, Schisandra chinensis 5-7% by weight and 9 to 11% by weight of the soft muscle. delete delete The hot water extract of the mixed herbal medicine according to claim 1, wherein the hot water extract has a calming effect. A beverage composition comprising hot water extract of the mixed herbal medicine of any one of claims 1 and 4. The beverage composition according to claim 5, comprising 15 to 25% by weight of hot water extract of the mixed herbal medicine and 7.5 to 15% by weight of fructooligosaccharide based on the total weight of the beverage composition.

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