KR102404644B1 - Composition for removing Hangover and health functional food comprising the same - Google Patents

Abstract

The present invention relates to a composition for relieving a hangover with improved blood alcohol concentration reduction and hangover relieving efficacy, and to a healthy food containing the same, and includes an extract of ginseng fruit, an extract of quince tree fruit and a dermis extract as active ingredients.

Description

Composition for removing Hangover and health functional food comprising the same

The present invention relates to a composition for relieving a hangover with improved blood alcohol concentration reduction and hangover relieving efficacy, and healthy food containing the same.

Modern people are exposed to various stresses, and the intensity of stress is increasing. People use different methods such as exercise, sleep, smoking, and travel to relieve stress, but it can be said that the most common method is to reduce stress through drinking (alcohol consumption). In addition, because Korean society tends to think that drinking has positive functions such as relieving stress, promoting friendship, and forming a sense of belonging, the drinking culture is particularly developed socially.

Due to the social background of Korea's drinking culture, consumer demand for hangover relieving products continues, and various studies are conducted to alleviate hangovers, and various products are actually sold on the market.

A hangover is a general term for physical and mental discomfort that occurs after drinking. Although the exact cause of hangover is not yet known, it is reported that it is caused by metabolites generated during alcohol metabolism.

Currently, the products sold on the market have not yet been objectively verified for their hangover relieving efficacy, and most of them contain a large amount of chemical ingredients, so the reality is that the reliability of the actual consumers is not generally high. Accordingly, in recent years, studies have been made on ingredients effective in reducing blood alcohol concentration and in relieving hangover from edible natural plants such as medicinal herbs.

For example, turmeric, galgeun, brown flower, chrysanthemum, alder, and Heotgae tree have long been known to have hangover relieving effects, such as Donguibogam, and it is known that aspartic acid and vitamin C contained therein exert an excellent hangover relieving effect. As an example, Korean Patent Registration No. 181168 discloses a hangover relieving composition comprising an alder tree extract and a rowan extract as active ingredients.

The inventor of the present invention has mixed extracts of numerous edible plants for the invention of a composition for relieving hangover, which is more excellent in reducing blood alcohol concentration and relieving hangover than the conventional composition for relieving hangover, and confirming whether there is a synergistic effect. was completed.

The present invention provides a hangover relieving composition with improved blood alcohol concentration reduction and hangover relieving efficacy, and healthy food containing the same.

The composition for relieving a hangover of the present invention for achieving the above object includes an extract of samchae, a fruit extract of Japanese quince, and a dermis extract as active ingredients.

The composition for relieving a hangover of the present invention includes a combination of a plant extract that exerts a synergistic effect in reducing blood alcohol concentration and in relieving a hangover, thereby exhibiting an excellent hangover relieving effect compared to the conventional composition for relieving a hangover.

In addition, healthy food containing the composition for relieving hangover can simultaneously secure health functions such as lowering blood sugar, anti-aging, and strengthening immunity, as well as excellent hangover relieving effect.

Hereinafter, the present invention will be described in detail. However, it is not limited only by the following content, and each component may be variously modified or selectively mixed as needed. Accordingly, it should be understood to include all modifications, equivalents and substitutes included in the spirit and scope of the present invention.

The term “extraction” used in the present invention refers to an operation of extracting only a specific substance from a solid or liquid using a solvent or reagent, for example, a medicinal component such as a plant, and an organic solvent such as water, ethanol (ethyl alcohol), ether, etc. It refers to dissolving and separating only specific components in a mixture, such as extraction using

The term “extract” used in the present invention is a substance separated by a conventional extraction process as described above from a desired raw material, and an extract using an extraction solvent or a concentrate thereof or a powder thereof, and the extract of the present invention includes all extracts exhibiting substantially the same effect using other extraction solvents as well as the above-described extraction solvents, and the extraction process of the present invention may be repeated several times, and thereafter may be subjected to a conventional concentration process, and reduced pressure It may be prepared in a powder state by an additional process such as distillation and freeze drying or spray drying.

<Composition for relieving hangover>

The composition for relieving a hangover of the present invention may include an extract of ginseng fruit, a fruit extract of a rhododendron tree, and a dermis extract as active ingredients. Based on the total weight of the composition, the active ingredient may be included in an amount of 65 to 95% by weight. The composition may further include one or more edible plant extracts as sub-components in addition to the active ingredient, and may further include other commonly used additives such as purified water and natural and/or artificial sweeteners constituting the remaining amount.

The composition for relieving a hangover of the present invention includes a combination of a plant extract that exerts a synergistic effect in reducing blood alcohol concentration and in relieving a hangover, thereby exhibiting an excellent hangover relieving effect compared to the conventional composition for relieving a hangover. In addition, in addition to the excellent hangover relieving effect, it is possible to simultaneously secure health functions such as lowering blood sugar, anti-aging, and strengthening immunity.

Samchae (Allium hookeri) is also called root leek, and is also called samchae (三菜) because it has a sweet, bitter, and spicy taste. The ginseng extract has the effect of improving diabetes through blood sugar control, preventing hangover, improving liver function, and improving asthma. Dietary sulfur, which is abundant in three vegetables, removes free radicals, thereby enhancing immunity. The extract of the three plants may be leaf extracts, flower extracts, stem extracts, or root extracts of the three plants, or a mixture thereof.

The rhododendron belongs to the leguminous family, and the bud of the hibiscus tree is called Goehwa (槐花) and the fruit of the hibiscus tree is called Goesil (槐實). The extract of the tree of fig. may be an extract of the fruit of the tree of fig. The fruit extract of the rhododendron is rich in rutin and germanium components, and while exhibiting an excellent hangover relieving effect, it exhibits an effect of improving the function of the liver, lungs, and large intestine and preventing hemorrhoids.

The dermis is another name for the tangerine peel, and it is the mature rind of Citrus unshiu Markovich or a closely related plant of the rutaceae family. Warm. The dermis extract exerts an excellent hangover relieving effect, while relieving the clogged air and strengthening the spleen function to relieve the symptoms of flatulence, belching, vomiting, nausea, flatulence, remove seawater, phlegm, and diuretic (利尿作用) can be promoted.

The three chaemon extracts, the extracts of the fruit of the Japanese apricots, and the extracts of the dermis are active ingredients in the composition, and may be included in an amount of 65 to 95%, for example, 70 to 90%, based on the total weight of the composition. If it is less than the content range, a sufficient hangover relieving effect cannot be expected, and if it exceeds the content range, there is an adverse effect on hangover relieving, and it may be undesirable because the taste may not be harmonized with other extracts.

The three chaechae extracts, the fruit extracts of the sycamore tree, and the extracts of the dermis may be mixed, for example, in a weight ratio of 10 to 80: 10 to 40: 10 to 80. When each extract of the main component has the above mixing ratio range, it can exert a synergistic effect in blood alcohol concentration and hangover relieving effect.

The composition may further include one or more sub-components that are plant extracts in addition to the active ingredient. Specifically, the plant extract may be at least one or more selected from the group consisting of a poison ivy extract, a baekchul extract, an osuyu extract, and an oleaginous extract.

The poison ivy belongs to the family Araliaceae and is also referred to as the hornwort. The young shoots of poisonous vitality are edible, and the roots are medicinal. The weakness is mild and the taste is bitter and spicy. Toxin helps with pain relief, sedation, vasodilation, and excitation of the respiratory center, and is used in oriental medicine to treat muscle pain, paralysis of the lower body, headache, and stroke. Compared to ganghwal (羌活, buttercup), antipyretic and sweating action is milder, so when used with ganghwal, it is particularly effective for neuralgia. The poisonous active extract may be a leaf or root extract, and the poisonous active extract has an excellent effect of excreting unnecessary moisture from the body as well as a hangover relieving effect.

Baekchul refers to the rhizome from which the bark of sapju belonging to the Asteraceae has been removed. Baekchul has a peculiar odor and tastes slightly bitter and sweet, viscous when chewed, and warm in nature. Baekchul extract exhibits hangover relieving effect and immune enhancement effect, suppresses intestinal tract and regulates excitatory action, protects anti-ulcer and liver function, vasodilation, diuresis and blood sugar lowering, anticancer action, etc. .

Osuyu uses the fruit as a medicine, and the main components of volatile essential oil are evoden, ocimene, and evodin, and the alkaloid contains evodiamine and rutaecarpine. The fruit of Osuyu is obtained from unripe greenish-brown fruits in September and used dried, and the fruit extract of Osuyu has a hangover relieving effect, warms the rain and stomach, helps the digestive function of the stomach, and is excellent for deworming, detoxification and diuresis. .

Jisil is the unripe fruit of the dandelion tree. The taste is bitter and sour, and the nature is cold. In addition to the hangover relieving effect, the oilseed extract has an anti-aging effect on the skin as it smoothes the peristalsis of the stomach and contains hesperidin and vitamin C.

The subcomponent may be contained in an amount of 5 to 30% by weight, for example, 10 to 25% by weight, based on the total weight of the composition. The sub-components can exert synergy in blood alcohol concentration and hangover relieving effect together with the above-mentioned active ingredients, while exhibiting health functions such as strengthening immune function, lowering blood sugar, anti-cancer action and skin aging prevention.

The composition, in addition to the above-mentioned components, other additives, for example, various nutrients, vitamins, electrolytes, flavoring agents, colorants, pectic acid and its salts, alginic acid and its salts, organic acids, protective colloidal thickeners, pH adjusters, Stabilizers, preservatives, glycerin, alcohol, carbonation agents used in carbonated beverages, etc. may be further included.

<Healthy food>

The healthy food of the present invention may be a food for the main purpose of relieving a hangover, including the composition for relieving a hangover. The health functional food is excellent in reducing blood alcohol concentration and relieving hangover, and at the same time, it is possible to simultaneously secure health functions such as lowering blood sugar, anti-aging, and strengthening immunity.

The healthy food, that is, health functional food, may be included together with food raw materials and food additives in addition to the composition, and the food raw materials and food additives may vary depending on the type of the food. Types of the health functional food include, for example, beverages, soups, teas, drinks, extracts, vitamin complexes, gels, candy, chocolate, gum, snacks, confectionery, pizza, ramen, other noodles, dairy products including ice cream, meat , sausage, bread, pills, effervescent tablets, etc., but is not particularly limited, and includes all foods in a conventional sense.

For example, when the health functional food is a beverage, it may further include purified water and food additives such as artificial or natural sweeteners, acidulants, and fragrances, like a conventional beverage. The natural sweetener may be, for example, monosaccharides such as glucose and fructose, disaccharides such as maltose and sucrose, and dextrin, cyclodextrin, and the like. The artificial sweetener may be saccharin, aspartame, or the like.

Based on the total weight (100% by weight) of the food excluding the compounding water (purified water) in the health functional food, the hangover relieving composition of the present invention may be included in 0.1% to 99.9% by weight, preferably 1 It may be included in an amount of from 11% to 50% by weight, for example, from 11% to 50% by weight.

Hereinafter, the present invention will be described in more detail through examples. However, the following examples are provided to help the understanding of the present invention, and the scope of the present invention is not limited to the examples in any sense.

Preparation of composition for hangover relief

[Examples 1-4 and Comparative Examples 1-6]

Hereinafter, the compositions for relieving hangovers of Examples 1 to 4 and Comparative Examples 1 to 6 were prepared.

<Example 1: Including active only>

Preparation of ginseng extract

The roots, leaves, flowers, and stems of the three plants are taken, dried and pulverized, immersed in 80% ethanol, extracted at a temperature of 70 ° C for 12 hours, the extraction residues are removed, concentrated under reduced pressure, and dried to obtain a powdered extract of three plants, respectively. got it

Manufacture of fruit extract

After removing the water from the fruits of the sycamore tree and pulverizing them, they were immersed in 80% ethanol and extracted at a temperature of 70 ° C. for 12 hours.

Dermal extract preparation

The dermis was taken, dried and pulverized, immersed in 80% ethanol, extracted at a temperature of 70° C. for 12 hours, the extraction residue was removed, concentrated under reduced pressure, and dried to obtain a powdery dermis extract.

Preparation of composition for relieving hangover

76 g of the three chae (root) extracts, 38 g of the fruit extract and 76 g of the dermis extract were mixed, and 200 g of a composition for relieving a hangover was prepared, including 10 g of purified water.

<Example 2: Including all active ingredients + sub-ingredients>

Preparation of poisonous extract

The leaves and roots of poison ivy were taken, dried and pulverized, immersed in 80% ethanol, extracted at a temperature of 70° C. for 12 hours, the extraction residue was removed, concentrated under reduced pressure, and dried to obtain a powdery extract, respectively.

Preparation of baekchul extract

The baekchul was taken, dried and pulverized, immersed in 80% ethanol, extracted at a temperature of 70 °C for 12 hours, the extraction residue was removed, concentrated under reduced pressure, and dried to obtain a baekchul extract in powder form.

Manufacture of Osuyu Fruit Extract

The fruit of Osuyu was taken, dried and pulverized, immersed in 80% ethanol, extracted at a temperature of 70° C. for 12 hours, the extraction residue was removed, and concentrated under reduced pressure and dried to obtain a powdery fruit extract of Osuyu.

Manufacture of fruit extract

After removing the water and pulverizing the oil, the oil was immersed in 80% ethanol and extracted at a temperature of 70 ° C. for 12 hours.

Preparation of composition for relieving hangover

52g of the three vegetables (root) extract of Example 1, 26g of fruit extract of Prunus asiatica, 52g of dermis extract, 16g of poison ivy extract, 16g of baekchul extract, 16g of Osuyu fruit extract and 12g of oleifera extract were mixed, 200 g of a useful composition was prepared.

<Example 3: Including active ingredient + part of sub-ingredients>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 2 described above, except that Osuyu fruit extract and fruit extract were not included.

<Example 4: Example of insufficient content of active ingredient>

Preparation of composition for relieving hangover

48 g of the samchae (root) extract, 24 g of the fruit extract and 48 g of the dermis extract were mixed, and 200 g of a composition for relieving a hangover was prepared, including 80 g of purified water.

<Comparative Example 1: No dermis extract among active ingredients + no sub-components>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 1 described above, except that the dermis extract was not included.

<Comparative Example 2: No extracts from three plants among active ingredients + no sub-components>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 1 described above, except that the three chae extracts were not included.

<Comparative Example 3: No dermis extract among active ingredients + all sub-components included>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 2 above, except that the dermis extract was not included.

<Comparative Example 4: None of the active ingredients, but not including the extract of the fruit of the sycamore tree + all of the sub-ingredients>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 2 described above, except that it did not include the fruit extract of the sycamore tree.

<Comparative Example 5: Including other plant extracts as active ingredients + without subcomponents>

Preparation of composition for relieving hangover

A hangover relieving composition was prepared in the same manner as in Example 1 above, except that the three chae extracts, the Alder tree fruit extract and the dermis extract instead of the hazelnut fruit extract, the alder tree extract, and the rowan fruit extract were included as main ingredients.

<Comparative Example 6: Commercially available hangover relieving drink>

A commercially available hangover relieving drink, 'CJ Healthcare Heotgae Condition', was prepared.

Experimental Example 1: Analysis of human blood alcohol concentration

Ten participants who obtained consent on the intention and method of the experiment were selected. Participants were selected into groups with similar age, gender, physical condition, and drinking habits. Before starting drinking, each of the compositions of Examples 1 to 4 and Comparative Examples 1 to 6 were ingested, or each composition was ingested after drinking was stopped, and the nurse collected blood over time after drinking was stopped and requested to Green Cross Co., Ltd. to measure the blood alcohol concentration. (Blood sampling interval: 60, 90, 150, 240 minutes after drinking) The results of the experiment are shown in Table 1.

As shown in Table 1, it was confirmed that Examples 1 to 4 including all active ingredients significantly lowered the blood alcohol concentration as time elapsed compared to Comparative Examples. Among them, it was confirmed that the effect of reducing the blood alcohol concentration of Example 2 including both the active ingredient and the minor ingredient was the most excellent. However, it was confirmed that Example 4, in which the content of the main component was less than 65%, was somewhat inferior in the effect of reducing the blood alcohol concentration compared to Examples 1 to 3 having a preferred content range of the main component.

On the other hand, Comparative Examples 1 to 4, which do not contain any one of the active ingredients, were inferior in the blood alcohol concentration reducing effect compared to the Examples even after a period of time, and containing a plant extract other than the active ingredient of the present invention as an active ingredient Comparative Example 5 was confirmed that the effect was significantly lower than that of Examples.

As a result, it can be confirmed that the combination of the active ingredients of the present invention, the extract of ginseng extract, the fruit extract of the sycamore tree, and the dermis extract exerts a synergistic effect in reducing the blood alcohol concentration compared to other plant extracts known to have the effect of reducing the blood alcohol concentration. there was.

Experimental Example 2

Hangover Relief Efficacy Evaluation

The compositions of Examples 1 to 4 and Comparative Examples 1 to 6 were prepared and the hangover relieving efficacy was compared. Five test personnel who answered that they had similar age, gender, physical condition, and usual drinking habits and had a hangover the next day after drinking were selected. After 2 hours have elapsed after having 5 inspectors drink a certain amount of alcohol (approximately 4 to 7 cups of soju (individual differences)), make them drink each of the above compositions, and the next day, such as headache, heartburn, sleep time, etc. Table 2 shows the symbols according to the evaluation criteria (bad: X average: △ good: ○ very good: ◎). (One week was given per person until the hangover relieving efficacy of one composition was evaluated, and the total experiment was conducted for 6 weeks.)

As shown in Table 2, Examples 1 to 4 containing all of the active ingredients were confirmed to have excellent hangover relieving efficacy compared to Comparative Examples. Among them, in the case of the composition of Example 2 containing both the active ingredient and the sub-component, it was confirmed that most of the inspectors responded that the hangover hardly appeared. However, Example 4, in which the content of the active ingredient was less than 65%, showed a somewhat lower hangover relieving effect compared to Examples 1-3.

On the other hand, Comparative Examples 1 to 4, which do not contain any one of the active ingredients, were able to confirm that the hangover relieving effect was inferior compared to the Examples even after time passed, and plant extracts other than the active ingredients of the present invention were used as active ingredients. Comparative Example 5 including the hangover relieving effect was also very inferior.

Accordingly, it was confirmed that the combination of the three active ingredients of the present invention, the extracts of ginseng extract, the fruit extract of the sycamore tree, and the dermis extract exerts synergy in the effect of relieving a hangover compared to other plant extracts known to have a hangover relieving effect.

Claims (9)

Containing ginseng extract, Prickly pear fruit extract, and dermis extract as active ingredients,
The active ingredient is included in 65 to 95% by weight based on the total weight of the composition for hangover relief. delete The method of claim 1,
The three-chae extract is a three-leaf extract, a flower extract, a stem extract or a root extract, or a mixture thereof, a composition for relieving a hangover. The method of claim 1,
In the composition, the three vegetables extract, the fruit extract of the sycamore tree and the dermis extract are mixed in a weight ratio of 10 to 80: 10 to 40: 10 to 80, a composition for relieving a hangover. The method of claim 1,
The composition, poison extract, baekchul extract, hangover relieving composition that further comprises one or more sub-components selected from the group consisting of extracts of osuyu oil and oleaginous extracts. delete 6. The method of claim 5,
The extract of the subcomponent is included in 5 to 30% by weight of the total weight of the hangover relief composition for hangover relief. A health functional food comprising the composition for relieving a hangover according to any one of claims 1, 3 to 5 and 7. 9. The method of claim 8,
The health functional food is a beverage, jelly, pill or effervescent tablet, health functional food.