KR101751211B1 - Composition for improving sexual function, Functional food Composition for improving sexual function comprising of the same and Manufacturing method thereof - Google Patents

Abstract

TECHNICAL FIELD The present invention relates to a composition for improving male sexual function, a functional food composition for improving male sexual function comprising the same as an active ingredient, and a method for producing the same, and is characterized by including a red ginseng extract and a yamgwan gum extract, and exhibits harmful side effects The male physiological function can be effectively improved by activating the normal physiological function of the human body.

Description

TECHNICAL FIELD The present invention relates to a composition for improving male sexual function, a functional food composition for improving male sexual function comprising the same as an active ingredient, and a method for producing the functional food composition,

The present invention relates to a composition for improving male sexual function, a functional food composition for improving male sexual function comprising the same as an active ingredient, and a method for preparing the same, and more particularly, to a composition for improving male sexual function, To a male sexual function composition capable of effectively improving male sexual function, a functional food composition for male sexual function improvement comprising the same as an effective ingredient, and a method for producing the same.

Male sexual dysfunction can be classified into two groups: erectile dysfunction, sexual dysfunction, erectile dysfunction, and erectile dysfunction.

Erectile dysfunction generally refers to erectile dysfunction, sexual dysfunctional erectile dysfunction, persistent and painful erectile dysfunction of the penis, and disruption of the spongy tissues and associated fascia of the penis. Erectile dysfunction is caused by psychologic impotence, organic impotence, or a combination of these two factors. This type of erectile dysfunction is classified as neurogenic, vascular and endocrine erectile dysfunction. Decreased sexual function is closely related to the deterioration of vital function, and in severe cases, it can develop into chronic erectile dysfunction.

In addition, sexual dysfunction caused by loss of ejaculatory ability is one of male sexual dysfunctions, like erectile dysfunction. It is known that sexual neuropathy is a symptom caused by the loss of sexual control ability because the balance between the peripheral nervous system and the central nervous system is destroyed and the cooperative system can not be maintained. A representative example of such a neurogenic disorder is premature ejaculation, which is an early ejaculation symptom of a male.

Most of the sexual enhancement drugs developed so far are mainly therapeutic drugs for people suffering from severe sexual dysfunction such as erectile dysfunction. These drugs for erectile dysfunction are classified into three types according to their functional groups. First, it promotes erection indirectly by inhibiting the enzyme called PDE5 (Phosphodiesterase type-5), which is present in the erectile tissue and interferes with the expansion of the cavernosum of the penis. Viagra and sildenafil Levitra based on Barden / GSK vardenafil, and Cials based on Lilly / ICOS tadalfil. However, in the case of Viagra, when nitrate is taken together with a cardiovascular drug, there is a disadvantage that it can cause a life risk due to a blood pressure diving phenomenon. Second, Caverject of Pharmacia, Muse of VIVUS, NexMed of BiPa, which is a major component of PGE1 (Prostaglandin E1) which directly acts on erectile tissues and enlarges the blood vessels and which is mainly composed of alprostadil, Befar). Third, there is the last of Uprima from Abbott, which is based on Apomorphine, a dopamine agonist acting on the dopamine D1 / D2 receptor in the brain. In addition, α-adrenergic receptor antagonists, guanylyl cyclase stimulators, and 5-hydroxytryptamine receptor agonists have been developed.

Psychotherapy and pharmacotherapy are used for the treatment of gonadal hypersensitivity, but commonly used drugs are psychotropic drugs that suppress the excitement of the sexual central nervous system or drugs for local anesthesia for the slowing of the sexual peripheral nerves. However, in the case of inhibiting the sexual central nervous system, there is a possibility that the sexual activity may become impossible due to the loss of sexual desire, and the local anesthetic agent causes erectile dysfunction due to the vasoconstrictive action and has a short duration.

In addition to therapeutic agents based on these specific chemical substances, agents for improving the sexual function of foods using natural products are known.

Korean Patent Laid-Open Publication No. 10-2001-0105720 (Nov. 29, 2001) discloses a food composition for preventing and treating sexual dysfunction, including a goat milk, a goat milk concentrate, and a goat milk using fermented milk of goat milk.

Korean Patent Laid-Open Publication No. 10-2002-0071326 (Sep. 12, 2002) discloses a composition for improving erectile dysfunction and food containing the same, comprising red ginseng extract powder, mallow oil, egg yolk oil, beeswax, soybean oil and lecithin.

Korean Patent Laid-Open Publication No. 10-2004-0014540 (2004.02.14.) Discloses a method and composition for enhancing sexual desire including a combination of L-arginine, ginseng, ginkgo biloba and damiana.

Korean Patent Publication No. 10-0463130 (Dec. 23, 2004) discloses a functional food for male sexual function improvement containing bokbunja, corn oil, red ginseng, sea cucumber and royal jelly.

Korean Patent Registration No. 10-0475647 (Mar. 10, 2005) discloses a composition for improving sexual dysfunction, which comprises an extract of Gossam ginseng.

Korean Patent Registration No. 10-0538717 (December 26, 2005) discloses a red ginseng extract for improving sexual function, an application thereof, and a manufacturing method thereof, including red ginseng extract, gugija, bokbunja, tosaja, omija and casualty extract.

As mentioned above, existing sexual function products are divided into two categories: erectile dysfunction medicine using chemicals and remedy using natural products. Conventional sexual function improvers, especially erectile dysfunction drugs, have been developed to provide immediate erection effects rather than sexual function improvement through normal human physiological functions of the human body. These products may have temporary erectile effects, Which may result in lower fitness and life-threatening side effects. In addition, a sexual function using a natural product showed a temporary effect or an insufficient sexual function. Therefore, there is a need to develop a composition for improving male sexual function which can effectively improve the sexual function by continuously activating the normal physiological function of the human body without being harmful to the human body.

KR 10-2001-0105720 A Nov. 29, 2001. KR 10-2002-0071326 A 2002.09.12. KR 10-2004-0014540 A 2004.02.14. KR 10-0463130 B1 Dec. 23, 2004. KR 10-0475647 B1 2005.03.10. KR 10-0538717 B1 2005.12.26.

It is an object of the present invention to provide a composition for improving male sexual function, which can effectively improve male sexual function by activating normal physiological function of the human body without showing harmful side effects to the human body, a functional food composition for improving male sexual function, And a method for producing the same.

In order to achieve the above object, the present invention provides the following means.

The present invention provides a composition for improving male sexual function comprising a red ginseng extract and a yam Kwan Mun extract.

The composition for male sexual function improvement is characterized in that the composition for improving male sexual function comprises at least one selected from the group consisting of bark extract, angelica extract, mulberry extract, maca extract, horsetail extract, zygomycet extract, caspase extract, An extract and a ginseng extract.

The composition for improving male sexual function comprises 50% by weight of a Rhodiola extract, 25% by weight of a yamgwan extract, 2% by weight of a bark extract, 2% by weight of a gold extract, 2% by weight of a mulberry extract, 2% 2% by weight of the extract, 2% by weight of caspase extract, 2% by weight of extract, 2% by weight of spinach extract, 2% 1% by weight of the Rhus verniciflua extract and 1% by weight of the extract.

The present invention also provides a functional food composition for male sexual function improvement comprising the composition for improving male sexual function as an active ingredient.

The present invention also relates to a method for preventing and / or treating casualties of casualties 2, 3, 4, 5, 5, 5, , 2% by weight of wheat, 2% by weight of astaxanthin, 2% by weight of Angelica gigantis, 1% by weight of Angelica, 1% by weight of pine nut, 1% (Step 1); Powdering the mixture to form a mixture powder (step 2); The mixture powder was put into a nonwoven fabric bag and put into a reflux extraction tank. 200 parts by weight of alcohol alcohol was added to the refluxing extraction tank together with 100 parts by weight of the mixture powder, Extracting the alcohol with refluxing for 12 hours to obtain a first extract (step 3); Removing the alcohol from the primary extract (step 4); Extracting the primary alcohol with the alcohol removed in the extraction container, adding the mixture powder and water after the reflux extraction in the step 3, and extracting the secondary extract by hot water extraction at a temperature of 90 to 100 ° C for 6 to 12 hours ( Step 5); Passing the secondary extract through an activated carbon filtration apparatus to adsorb and remove an organic substance (step 6); The step (6) of removing the protein, carbohydrate and fiber by passing the secondary extract through the ultrafast centrifugal separator (step 7); Filtering the second extract obtained through step 7 using a microfilter system (step 8); (Step 9) of preparing a composition for improving male sexual function by concentrating the secondary extract obtained in step 8 to 60-65 brix in the range of 70-80 ° C using a vacuum concentration apparatus; And a method for producing a male sexual function improving composition.

In the step 1, 1 to 10 parts by weight of at least one selected from the group consisting of safflower, horse chestnut, Chinese caterpillar, buckwheat, camellia, cinnamon, cinnamon, have.

The composition for improving male sexual function according to the present invention has an advantage that male sexual function can be effectively improved by activating the normal physiological function of the human body without showing adverse side effects to the human body.

Hereinafter, the present invention will be described in detail.

First, the composition for improving male sexual function according to the present invention will be described.

The present invention provides a composition for improving male sexual function comprising a red ginseng extract and a yam Kwan Mun extract.

Honggyeongcheon (Rhodiola) herein is intended to mean a herbaceous perennial plant that grows in the alpine plants belonging to the Fiji group, gyeongcheon and honggyeongcheon, been reported that worldwide 96 to 50% of paper and formatting particularly in China. In addition, it is a plant with special adaptability that can survive at 1700-2300 m above sea level with low temperature, dry, low oxygen, strong ultraviolet ray, and large temperature difference between day and night.

Recently, it is a kind of health medicinal plant discovered after ginseng and goose guppy, and it has the nickname of highland ginseng because it can regenerate and overcome disease and poison. Hongkongcheon is used for food and medicinal use and is used as a sedative, antipyretic, and astringent agent in the private sector. In Oriental medicine, it has excellent effects on tonic medicine, especially senile heartburn and soundness. It is used as powder medicine or bathing oil for diabetes, anemia, Nervous breakdown, and post-natal treatment. Major components separated from roots and stems of Hongcheon Stream include flavonoids, monophenoids, phenylpropanoids and phenylethanol derivatives, and aliphatic glycosides. The rhodochrine used in the present specification is included in the form of an extract, and roots of Rhodiola can be used.

In this specification, the term " Lespedeza cuneata G.Don " refers to a perennial plant of soybean and is called a variety of names such as anthracnose and perennial plant, and is distributed in Japan, China, and Taiwan including Korea. It is used as medicines for related diseases because it protects function, improves lung function and blood circulation. Useful physiologically active substances contained in the doorway include, but are not limited to, pinitol, avicularin, trifolin, beta-sitosterol and quercetin, kaempferol, There are several kinds of flavonoids such as vitexin. It is known that there is an antimicrobial, antioxidant effect and skin photo anti-depression effect as well as a high vitamin E content useful for prevention of aging. The nightstand used in this specification is included in the form of an extract, and any one or more of the leaves or stems of the nightstand can be used.

The composition for improving male sexual function according to the present invention is a composition for improving male sexual function comprising at least one selected from the group consisting of a herb extract, a coriander extract, a mulberry extract, a maca extract, a herb extract, a herb extract, a caspase extract, Extracts, Rhus verniciflua extracts and ginseng extracts.

The present invention also relates to a method for the treatment and / or prevention of an infectious disease, comprising the steps of: 50% by weight of a Rhodiola extract, 25% by weight of a yam Kanto extract, 2% by weight of a bark extract, 2% 2%, 2%, 2%, 2%, 2%, 2%, 1%, 1%, 1%, 1%, and 1%, respectively, of the extract of Rhus verniciflua And 1% by weight of the extract of Gossam gypsum.

In the present specification, Dendrobium moniliforme means perennial herbaceous belonging to the orchidaceous family. It grows to about 20 to 50 cm and grows in Korea, Japan, and China. The whole plant, except for roots, is called bamboo. It is used as a medicinal product after being dried in the sun after cutting the outpost when blooming in summer. It is used as antipyretic analgesic treatment, cataract treatment, noodle, and tonic. The bark used in the present specification is contained in the form of an extract, and a part or all of the ground part of the herb can be used, and preferably all of the ground part can be used.

In this specification, Rosa laevigata Michx. Refers to an evergreen shrub belonging to Rosaceae . It is also called rose, white mauve, Hassan, sacrum, embroidery, and sword. The country of origin is China, Japan, and Taiwan. Its height is 5m, its stem is reddish brown, there is a thorn like a hook, the leaf is a triple leaf, and the sides are glossy. Flowers bloom in June to July at the end of small branches. The fruit is elliptical, with thorns and ripen in yellow. For medicinal purposes, roots, leaves, flowers and berries are used. For food use, berries, petals and lentils are used. Citrus acid, malic acid, tannin, resin, vitamin C, saponin, fructose, sucrose, starch, ), Etc. These fruits are known to have effects such as tonic, gangjeong, convergence, antibacterial, and cholesterol lowering action. Therefore, it is possible to prevent chronic diarrhea, polyuria, wells, urinary frequency, cold sweat, chronic enteritis, And the like. As used herein, progenitor is included in the form of an extract, and any one or more selected from the group consisting of roots, leaves, flowers, and fruits can be used.

In this specification, Eucommia ulmoides is a deciduous tree belonging to Eucommiaceae. It is originated in the vicinity of Sichuan province in China, and is a rare tree belonging to 1, 1, and 1 species, like a ginkgo tree. . The pharmacokinetics of diabetes mellitus are as follows: diabetes mellitus, diabetes mellitus, diabetes mellitus, diabetes mellitus, diabetes mellitus, diabetes mellitus. It also enhances the adrenocortical hormone of the animal, shows anti-inflammatory action, and regulates the analgesic action and the body's immune function, thereby suppressing and enhancing cellular immunity. It also shortens the bleeding time, shows diuretic action, has antiallergic action and uterine contraction. The bivalves used in the present specification are included in the form of an extract, and bivalves can be used.

Maca ( Lepidium meyenii Walpers) refers to a plant belonging to the genus Brassicaceae. It is a perennial plant cultivated mainly in the highlands of over 4,000 m above sea level in the Peruvian Andes, and its potato-like root is native to the Andes Is being used as a major food resource. Maca grows in a difficult natural environment such as cold, strong winds, drought, and therefore has a very strong vitality. It has high nutritional value because it contains carbohydrates, proteins, lipids, vitamins, minerals and fibrin. It has various physiological functions such as alkaloids, steroids, tannins and saponins The substance is found to be present. The maca used in the present invention is contained in the form of an extract, and a root powder can be used.

In the present specification, Yinsookgwa refers to the outpost of Epimedium koreanum Nakai, and other names include a strong, a dragonfly, a foxglove, a dragonfly, a lily of the valley, an age scale, . Stem and leaf, stem is thin and columnar, surface is yellowish green to light yellow and polished. The leaf on the stem is a little pointed. The upper epidermis is yellowish green, the lower epidermis is gray green, the main vein is 7 ~ 9 lines, and the lower part is thin and long and the hair is sparse. There is no smell and taste is a little bit. There is no smell and taste is a little bit. It is used for erectile dysfunction, oil wells, uterine circulation, hypothermia, skin paralysis, amenorrhea, amenorrhea, dysmenorrhea, weakness of the lower back and knee, hypertension and poliomyelitis. Pharmacological actions promote semen secretion, decrease blood pressure, increase coronary blood flow, Blood glucose lowering, cholesterol lowering, immune function enhancement, Jinhae, genomes, pyeongcheon, sedation, acne, and inflammation were reported. As used in the present specification, egg shells are included in the form of extracts, and one or more of leaves or stems may be used.

Bored in this specification is also referred to as Bacillus thuringiensis, which means that the mature fruit of the one-year-old or perennial herb Tribulus terrestris L., belonging to Zygophyllaceae, is dried. Saponin, essential oils, alkaloids, and resins. Dongwoo Bamboo is a herbal medicine used for diuretic, headache, and menstrual irregularities. The spermatozoa used herein are included in the form of extracts, and the fruits of the S. sperm can be dried and used.

Torilidis Fructus in this specification refers to the fruit of Torilis japonica (Houtt.) DC.), The biennial grass of Umbellifreae, and is known to be spicy, warm and poisonous. In one room, the herbal medicine which is made by drying the fruit is called "Sasangja" and it is distributed in Korea, Japan, China, Taiwan, India and Myanmar. The pharmacological effects are antigenic impregnation, sexual hormone-like action and antiallergic action, astringent antiinflammatory drug and itching effects are effective, and the major components of the casualties are tililin (torilin), toriloline It has been reported that a sesquiterpene-based compound is contained. As used herein, casualties are included in the form of extracts, and the berries can be used by being dried.

In the present specification, Cynomolium songaricum is a perennial plant herbaceous plant of plant and plant, and is also referred to as a cereus or a fungicide. The plant is a plant native to China and has been used as a medicinal plant to display the ovary and add blood to the plant. The rootstock is thick and short, and there are many absorbed groups in this area. The stem is cylindrical, the color is deep reddish purple, the height is 20 to 100 cm, the diameter is 3 to 6 cm, most of it is buried in sand, the base is thick and sturdy, and there are scaly scaly leaves. As used herein, suppositories are included in the form of extracts, and dried rootstocks can be used.

In the present specification, Achyranthes refers to herbaceous herbaceous plants or their roots belonging to the bacterium, and the grass is the name given to the fact that the node is swollen like a cow's knee. The general efficacy of the wax is that it works to smooth the blood circulation and remove the eosinophilia, and it is used for the treatment of physiological impurity, postpartum abdominal pain, and also works well in organs such as liver and kidney. The mist used in the present invention is contained in the form of an extract, and roots can be used.

In the present specification, Cnidium officinale MAKINO refers to perennial herbaceous plants belonging to the mountain type and the herbaceous plant is dried in one direction and is mainly used for gynecological diseases such as headache, infertility, menstrual irregularities, anemia, The chemical components of the crown palm are phthalide components such as cnidilide, neocnidilide, ligustilide, butylphthalide, senkyunolide, etc. Is known to be contained. The wax used in the present invention is contained in the form of an extract, and dried roots can be used.

In the present specification, Angelica gigas Nakai, A. sinensis DIELS, A. acutiloba KITAG. And root of relative plants belonging to Umbelliferae belong to perennial herbaceous plants belonging to the genus Angelica gigas Nakai, A. sinensis DIELS, It is known that it has the efficacy of bleeding blood, landscape mail, Root is sedative, shrinking action, blood pressure lowering action. Root essential oil aqueous solution is used for arthritis. It is said to have analgesic action and anti - inflammatory action. It is used mainly for anemia, women 's disease, postpartum recovery of pregnant woman, It is used for swelling. As used herein, Angelica gigas is contained in the form of an extract, and dried roots can be used.

In this specification, Nelumbo nucifera seed means a seed which has removed the mature fruit husk of lotus flower, and there is no smell, flavor is slightly sweet, and little bitterness. The sweet potato contains a large amount of starch and a sugar called raffinose. The pharmacological effect is known to enhance the functions of the spleen and stomach, sleep anxiety, skin whitening, inflammation relief, and skin wound healing. The livestock meat used in the present invention is contained in the form of an extract.

In the present specification, Dendropanax morbifera belongs to Araliaceae, and refers to evergreen broad-leaved arboreous trees native to Jeonnam coastal area and Jeju Island in the whole world, and yellow sap is produced when scarring on bark, And the yellow sap is used as a paint. The main component of the Hwangchu tree is essential oil and it is composed of light yellow and dark liquid. It is known that the efficacy of Hwangchil is improved blood circulation, liver function, sulfation, immunity, nervous stability, antimicrobial activity and anticancer activity. As used herein, the woody bittern is included in the form of an extract, and any one or more selected from the group consisting of stem, seed, leaf, root, and shell may be used.

Sumac (Rhus verniciflua Stokes) herein anacardiaceae will mean deciduous broad-leaved arborescent belonging to the (Anacardiaceae family), the Central Asian plateau and the Himalayan province is known as the country of origin, subtropics around the tropics, currently the world And temperate regions. It is mostly deciduous or evergreen, and most of it is arboreous or shrubby, and some of it is vine. Lacquer fluid is called liquid and it is said that liquid of lacquer tree is dried in old one and the dryness of dried lacquer is eliminated and blood circulation is promoted, It is known that it is effective for preservation, dryness, and gynecomastia. Recently, anticancer effect has also been reported. The lacquer tree used in the present invention is contained in the form of an extract, and any one or more of bark or woody part can be used.

In the present specification, Sophora flavescens Aiton refers to a perennial plant of a dicotyledonous rosemary bean and grows in a sunny grass. In one room, dried roots are called gosam, which is a herbal medicine described in Korean Pharmacopoeia. It has ginseng effect and prescribes to digestive problems, neuralgia, hepatitis, jaundice and hemorrhoids. Gosam contains mainly flavonoids and alkaloids, and studies on neuroprotection and glucosidase inhibition have been reported. The ginseng used in the present invention is contained in the form of an extract, and dried roots can be used.

It is preferable that the composition for improving male sexual function according to the present invention is prepared at the above composition ratio, and if the composition ratio is out of the range, side effects such as diarrhea may occur.

The present invention relates to a composition for improving male sexual function comprising at least one selected from the group consisting of safflower extract, Ganoderma extract, Cordyceps sinensis extract, buckwheat extract, Camellia sinensis extract, camomile extract, cinnamon tree extract, May be included.

100 parts by weight of the composition for male sexual function improvement is divided into 100 parts by weight of a composition selected from the group consisting of a safflower extract, a chewing gum extract, a Chinese cabbage extract, a buckwheat extract, a camellia extract, a chewy gum extract, a cinnamon tree extract, Or more and 1 to 10 parts by weight. By further including the above extract, the sexual function improving effect can be further improved.

In the present specification, safflower (Carthamus tinctorius L.) refers to a plant belonging to the family Asteraceae (Compositae), and its petal has been used for women's diseases since ancient times. , Decrease myocardial infarction, inhibit platelet aggregation, and have been reported to have an anticancer effect. As used herein, the safflower is included in the form of an extract, and petals may be used.

In this specification, Gastrodia elata Blume refers to a tuber of a perennial herbaceous plant belonging to Orchidaceae which is native to Korea, China and Japan. In the sacred Materia Medica, This is known as a poisonous medicinal herb. Clinical efficacy of Chunma is found in various primary literature such as primary herbal medicine, Dongbokgam, and it is reported to be effective for hypertension, paralysis, headache, paralysis, neurological diseases, diabetes, epilepsy and anemia. In the private sector, chimpanzees have been used to treat headaches, anemia, limb paralysis, and stroke. The chewing gum used in the present invention is contained in the form of an extract, and tubers (tubers) can be used.

In the present specification, Cordyceps sinensis is a type of mushroom mushroom which is a type of fungus, which is a kind of fungus, which enters into the body of living insects at a time when temperature and humidity are high, . The pharmacological actions of Cordyceps were reported to be central nervous system depression, body temperature depression, immune function hyperactivity, anticancer, cardiac hypertrophy, bronchodilation, increase of corticosteroid action, antipyretic, anti - aging, anti - inflammatory and antimicrobial action. Cordyceps, as used herein, is included in the form of an extract.

In the present specification, buckwheat refers to Fagopyrun esculentum Moench as a scientific name. Generally, when the flower starts to bloom, the upper branch with leaves and flowers is dried and used as pharmaceutical raw material. The main component of buckwheat is rutin, which varies depending on the length of planting and plant parts, and how the herb is dried. The action of vitamin P in the routine lowers the permeability of capillaries and restores vulnerability. As used herein, buckwheat is included in the form of an extract, and any one or more selected from the group consisting of seed, seed coat and stem can be used.

In the present invention, Camellia haponica L. refers to a tree of Camelliae and Camelliae. Camellia leaf is known to be effective against psoriasis, throat pain, burns. Camellia flower is a camellia flower that is dried as a Chinese medicine and is also known as reddish flower. Camellia is used for liver and menopause, and it is known to be effective for blood, hemostasis, and acidic blood. The camellia used in the present invention is contained in the form of an extract, and any one or more selected from the group consisting of leaves, flowers and buds can be used.

Aralia cordata THUNB. Is a perennial herb that belongs to Araliaceae. It has a height of 1.2m and the stem has short hairs throughout. In the spring and autumn roots and root roots in the sunshine, dried in the sun, is used to treat migraine. The taste is spicy, the quality is warm and non-toxic, and it has efficacy such as fever, analgesic action, anti-inflammatory action, anti-inflammatory action, blood coagulation promoting action, As a medicine, it uses roots, and it is used for prescription such as the effect of dehumidification of goby winds, pneumoconiosis, nonspecificity, neuralgia, headache, aftereffects of paralysis, improvement of blood circulation. The chewing gum used herein is contained in the form of an extract, and the roots can be used by drying.

Cinnamomum cassia PRESL in the present specification means belonging to the genus Camphoraceae. The main ingredients are 19-acetylcycinol A, anhydroglycine alanine, casioside, eugenol, cinnamic aldehyde and cinnamic ethyl acetate. They are effective against fever, analgesic action, cardiovascular action, antimicrobial action and antiviral action Is known. The cinnamon tree used in the present invention is contained in the form of an extract, and any one or more of branches or shells can be used.

In the present specification, spikelet (filamentous fungus) is a filostakisnigravaya. Hennonis ( Phyllostachys nigra var. Henonis ) is a perennial evergreen tree that grows on the side and grows up to 10 meters in height. Bamboo shoots appear in April to May and are brown and edible. It is included in the form of a powdered extract used in the present invention, and any one or more of stems or leaves may be used.

Morinda officinalis (Morinda officinalis) in this specification means that it is said to be a sea wave pole or a wave pole. It has the efficacy to improve Xinyang, to strengthen bones and muscles, to exorcise excitement and to eliminate abdomen. It has the effect of cold, pain in the abdomen, urinary incontinence, cold and cold uterus, Treat knee and back pain. As used herein, the pyrethroid is contained in the form of an extract, and roots can be used.

Zedoariae Rhizoma refers to the rhizome of Curcuma zedoaria (BERG.) Rosc.), A perennial herb of ginger and ( Zingiberaceae ), and is used for the purposes of hibernation, hemorrhage , pain and the like. Further, it has been used for the purpose of symptom improvement and treatment of various diseases from ancient times, and it is a herbal medicine which has been proved to be safe for human body. The patches used herein are included in the form of an extract.

The composition for improving male sexual function has an advantage that male sexual function can be effectively improved by activating the normal physiological function of the human body without exhibiting harmful side effects to the human body.

The present invention also provides a functional food composition for male sexual function improvement comprising the composition for improving male sexual function as an active ingredient. The functional food composition for male sexual function improvement may be a composition for improving or preventing erectile dysfunction.

The functional food composition for improving male sexual function comprising the composition for improving male sexual function as an active ingredient may further comprise suitable carriers, excipients and diluents conventionally used for the production thereof.

Examples of the food composition of the present invention include foods, food additives, beverages or beverage additives.

In the present specification, the term " food " means a natural product or a processed product containing one or more nutrients. Preferably, it means that the food product can be directly eaten through a certain processing step. It is intended to include food, food additives, health functional foods and beverages.

Examples of foods that can include the male sexual function improving composition include various foods, beverages, gums, tea, vitamin complexes, and functional foods. In addition, in the present invention, the food contains a special nutritional food. Kimchi, pickled foods, beverages, natural seasonings, vitamins, alcoholic beverages, alcoholic beverages and other health foods, processed foods, fish products, tofu, jelly, noodles, health supplements, seasoning foods, sauces, confectionery, dairy products, But are not limited to, supplements. The food, beverage or food additive may be prepared by a conventional production method.

In the present invention, the functional food refers to a food group which is imparted with added value to function and express the function of the food by using physical, biochemical, biotechnological techniques and the like, the regulation of the biological defense rhythm of the food composition, Means a food which is processed and designed so that the body control function regarding the body is sufficiently expressed to the living body. The functional food may include a food-acceptable food-aid additive, and may further comprise suitable carriers, excipients and diluents conventionally used in the production of functional foods.

In the present invention, the beverage is intended to include a functional beverage, which means a general term of drinking to relieve thirst or to enjoy a taste. The beverage is not particularly limited as long as it contains the male sexual function improving composition as an active ingredient as an essential ingredient at the indicated ratio, and may contain various flavors or natural carbohydrates as an additional ingredient . In addition, the food composition of the present invention may further contain flesh for the production of natural fruit juice, fruit juice drink, and vegetable drink.

In addition to the above, the composition of the present invention can be used as a flavoring agent such as various nutrients, vitamins, minerals, synthetic flavors and natural flavors, colorants and enhancers, pectic acid and its salts, alginic acid and its salts, Stabilizers, preservatives, glycerin, alcohols, carbonating agents used in carbonated drinks, and the like.

The functional beverage according to the present invention can be used to control the bio-defense rhythm of the beverage group or beverage composition to which the added value is imparted so that the function of the beverage acts on the specific purpose by physical, biochemical or biotechnological techniques, Means a beverage which has been designed so that the body control function related to restoration and the like is sufficiently expressed in the living body.

The functional beverage has no particular limitation on the other components other than the composition containing the male sexual improving composition as a special ingredient in the indicated ratio and may contain various flavors or natural carbohydrates as an additional ingredient such as ordinary beverages .

In the functional food composition for improving male sexual function of the present invention, the amount of the composition for improving male sexual function, which is an effective ingredient, may be in the range of 0.00001% to 50% by weight of the total food. In the case of beverage composition, But the present invention is not limited thereto. The amount of the surfactant may be from 0.001 g to 50 g, preferably from 0.01 g to 10 g, based on 100 ml.

Next, a method for producing a male sexual function improving composition according to the present invention will be described.

The method for producing a male sexual function improving composition of the present invention comprises:

50% by weight of Hongkyung Stream, 25% by weight of the night school door, 2% by weight of gypsum, 2% by weight of gold skeins, 2% by weight of mung bean, 2% by weight of maca, 2% (Step 1) of preparing a mixture by mixing 2% by weight of wheat, 2% by weight of astragalus, 1% by weight of Angelica gigas, 1% by weight of pine nut, 1%

Powdering the mixture to form a mixture powder (step 2);

The mixture powder was put into a nonwoven fabric bag and put into a reflux extraction tank. 200 parts by weight of alcohol alcohol was added to the refluxing extraction tank together with 100 parts by weight of the mixture powder, Extracting the alcohol with refluxing for 12 hours to obtain a first extract (step 3);

Removing the alcohol from the primary extract (step 4);

Extracting the primary alcohol with the alcohol removed in the extraction container, adding the mixture powder and water after the reflux extraction in the step 3, and extracting the secondary extract by hot water extraction at a temperature of 90 to 100 ° C for 6 to 12 hours ( Step 5);

Passing the secondary extract through an activated carbon filtration apparatus to adsorb and remove an organic substance (step 6);

The step (6) of removing the protein, carbohydrate and fiber by passing the secondary extract through the ultrafast centrifugal separator (step 7);

Filtering the second extract obtained through step 7 using a microfilter system (step 8);

(Step 9) of preparing a composition for improving male sexual function by concentrating the secondary extract obtained in step 8 to 60-65 brix in the range of 70-80 ° C using a vacuum concentration apparatus;

.

In step 1, 1 to 10 parts by weight of at least one selected from the group consisting of safflower, horse chestnut, Chinese cabbage, buckwheat, camellia, cinnamon, cinnamon, .

The size of the powder in the step 2 is not particularly limited.

The purity of the alcohol in step 3 is not particularly limited.

In the step 4, the method for removing the alcohol from the primary extract is not particularly limited. In one method, it can be removed using a vacuum distillation apparatus.

In the step 5, the water is preferably added in an amount of 600 to 1000 parts by weight based on 100 parts by weight of the mixture powder of the step 2.

In step 6, not only the organic material but also residual pesticide components and heavy metals can be adsorbed and removed.

In step 7, protein, carbohydrate, and fiber can be removed using an ultrafast centrifuge at 15,000 to 20,000 rpm.

In step 8, the inert macromolecule can be efficiently removed by circulating it through a microfiltration device having a size of 0.45 mu m.

Hereinafter, the constitution and effects of the present invention will be described in more detail through examples. These embodiments are only for illustrating the present invention, and the scope of the present invention is not limited by these embodiments.

2% by weight of root, 2% by weight of ginseng root, 2% by weight of ginseng root, 2% by weight of maca root powder, 2% by weight of hornbill leaf, 2% , 2% by weight of casualties, 2% by weight of root rot root, 2% by weight of astragalus root, 2% by weight of rootstock root, 1% by weight of angelica root, 1% by weight of pectin, 1% by weight of yellowtail bark, And 1% by weight of roots were mixed to prepare a mixture. The mixture was pulverized to prepare a mixture powder. The mixture powder was put into a nonwoven fabric bag and put into a refluxing extraction tank. Then, 200 parts by weight of alcohol alcohol was added to the refluxing extraction tank for 100 parts by weight of the mixture powder, The primary alcohol was extracted with circulating reflux to obtain the first extract. The alcohol was removed from the primary extract using a vacuum distillation apparatus. The primary extract from which the alcohol was removed in the extraction vessel, the mixture powder after the reflux extraction in the step 3, and water were heated and extracted with hot water for 10 hours at a temperature of 100 ° C to obtain a secondary extract. The water was added in an amount of 600 parts by weight based on 100 parts by weight of the mixture powder before the reflux extraction. The secondary extract was passed through an activated carbon filtration apparatus to adsorb and remove organic substances. The secondary extract from which the organic material was removed was passed through an ultra-high speed centrifuge at 15,000 to 20,000 rpm to remove proteins, carbohydrates and fibers. The protein, carbohydrate, and fiber-free secondary extracts were filtered using a microfiltering system to remove the inactive macromolecules. The second extract from which the inactive macromolecule was removed was concentrated to 65 brix at 75 ° C using a vacuum concentrator to prepare a composition for improving male sexual function.

In Example 1, 100 parts by weight of the mixture was mixed with 1 part by weight of safflower petals, 1 part by weight of tuberous tubers (tubular stem), 1 part by weight of Cordyceps, 1 part by weight of buckwheat stem, 1 part by weight of camellia leaves, , 1 part by weight of Cinnamomum cassia bark, 1 part by weight of Japanese persimmon stalk, 1 part by weight of Phytophthora camphorata root, and 1 part by weight of Entomix were further mixed to prepare a male sexual function improving composition.

[Comparative Example 1]

A composition for improving male sexual function was prepared in the same manner as in Example 1, except that the roots were used alone in place of the mixture.

[Comparative Example 2]

In Example 1, a composition for improving male sexual function was prepared in the same manner as in Example 1, except that the mixture was used as a single leaf.

[Experimental Example 1]

The male sexual function composition prepared in Example 1, Example 2, and Comparative Example 1 and Comparative Example 2 was filled in a hard capsule having a capacity of 300 mg. 40 married males aged between 30 and 60 who have no physical or mental illnesses such as hypertension, diabetes, liver disease, kidney disease, and psychiatric disorders and who have symptoms of sexual dysfunction 10 tablets of Example 1, 10 tablets of Example 2, 10 tablets of Comparative Example 1, and 10 tablets of Comparative Example 2), each of the hard capsules prepared above was inoculated into hard capsules 3 times a day for 30 days, . The subjects were subjected to a foot function measurement questionnaire using the International Index of Erectile Function (IIEF) questionnaire. The foot function measurement questionnaire was developed by Rosen in terms of foot function (6 questions), optimality (2 questions), sexual desire (2 questions), sexual satisfaction (3 questions) and overall sexual satisfaction (2 questions) 5 items. Surveys were conducted before and after ingestion. The answers to each of these questions were divided into six grades of 0 to 5, and the scores of the subjects were combined. The average values of the scores were shown in Table 1 below.

Foot function ¹ Maximum capacity ² Sexuality ³ Sexual Satisfaction ⁴ Overall Satisfaction ⁵ Before ingestion After ingestion Before ingestion After ingestion Before ingestion After ingestion Before ingestion After ingestion Before ingestion After ingestion Example 1 12.4 ± 0.5 20.7 ± 2.5 5.5 ± 0.5 7.4 ± 0.4 6.9 ± 0.4 7.9 ± 0.2 5.6 ± 0.5 10.1 ± 0.7 4.2 ± 0.4 7.1 ± 0.3 Example 2 12.3 ± 0.4 22.7 ± 2.1 5.4 ± 0.4 7.6 ± 0.3 6.8 ± 0.3 8.1 ± 0.2 5.5 ± 0.4 10.6 ± 0.6 4.1 ± 0.3 7.8 ± 0.2 Comparative Example 1 12.6 ± 0.4 15.1 ± 2.4 5.6 ± 0.4 6.2 ± 0.3 7.0 ± 0.4 7.3 ± 0.3 5.7 ± 0.5 8.1 ± 0.7 4.3 ± 0.5 5.8 ± 0.5 Comparative Example 2 12.5 ± 0.5 13.9 ± 2.3 5.8 ± 0.4 6.1 ± 0.3 7.0 ± 0.3 7.2 ± 0.3 5.8 ± 0.6 7.7 ± 0.6 4.3 ± 0.3 5.2 ± 0.3

¹ 6 questions: possible total score 1 ~ 30

² 2 questions: possible total score 0 ~ 10

³ 2 questions: possible total score 2 ~ 10

⁴ 3 questions: possible total score 0 ~ 15

⁵ 2 questions: possible total score 2 ~ 10

Table 1 shows that the mean score of paw function, calmness, libido, sexual satisfaction and overall satisfaction in the International Index was significantly increased by the ingestion of the composition for male sexual function improvement of Example 1.

When the composition for male sexual function improvement of Example 2 was ingested, the increase in average score was larger than that of the composition for male sexual function improvement of Example 1, while the composition for male sexual function improvement of Comparative Example 1 and Comparative Example 2 , It can be seen that the increase in the average score is smaller than that in the case of taking the composition for male sexual function improvement of Example 1.

On the other hand, none of the subjects among the 40 subjects answered that side effects such as diarrhea occurred during the intake of the male sexual function-improving composition for 30 days.

Therefore, the composition for improving male sexual function of the present invention has the advantage of improving male's sexual function as well as improving overall physical condition of a human body without adding side effects by adding natural materials to the rhyolite or yam door at an optimal content ratio.

Claims (6)

delete delete delete delete delete 50% by weight of Hongkyung Stream, 25% by weight of the night school door, 2% by weight of gypsum, 2% by weight of gold skeins, 2% by weight of mung bean, 2% by weight of maca, 2% (Step 1) of preparing a mixture by mixing 2% by weight of wheat, 2% by weight of astragalus, 1% by weight of Angelica gigas, 1% by weight of pine nut, 1%
Powdering the mixture to form a mixture powder (step 2);
The mixture powder was put into a nonwoven fabric bag and put into a reflux extraction tank. 200 parts by weight of alcohol alcohol was added to the refluxing extraction tank together with 100 parts by weight of the mixture powder, Extracting the alcohol with refluxing for 12 hours to obtain a first extract (step 3);
Removing the alcohol from the primary extract (step 4);
Extracting the primary alcohol with the alcohol removed in the extraction container, adding the mixture powder and water after the reflux extraction in the step 3, and extracting the secondary extract by hot water extraction at a temperature of 90 to 100 ° C for 6 to 12 hours ( Step 5);
Passing the secondary extract through an activated carbon filtration apparatus to adsorb and remove an organic substance (step 6);
The step (6) of removing the protein, carbohydrate and fiber by passing the secondary extract through the ultrafast centrifugal separator (step 7);
Filtering the second extract obtained through step 7 using a microfilter system (step 8);
(Step 9) of preparing a composition for improving male sexual function by concentrating the secondary extract obtained in step 8 to 60-65 brix in the range of 70-80 ° C using a vacuum concentration apparatus;
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In step 1, 1 part by weight of safflower petals, 1 part by weight of tuberous tubers (tubers), 1 part by weight of Cordyceps, 1 part by weight of buckwheat stem, 1 part by weight of camellia leaves, 1 part by weight of roasted roots , 1 part by weight of cinnamon tree branches, 1 part by weight of japanese stalks, 1 part by weight of root fragments and 1 part by weight of seeds,
A method for preparing a composition for improving male sexual function.