KR102013567B1 - ６-(피페리딘-４-일옥시)-２ｈ-이소퀴놀린-１-온 하이드로클로라이드의 다형체 - Google Patents

６-(피페리딘-４-일옥시)-２ｈ-이소퀴놀린-１-온 하이드로클로라이드의 다형체 Download PDF

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KR102013567B1
KR102013567B1 KR1020147003355A KR20147003355A KR102013567B1 KR 102013567 B1 KR102013567 B1 KR 102013567B1 KR 1020147003355 A KR1020147003355 A KR 1020147003355A KR 20147003355 A KR20147003355 A KR 20147003355A KR 102013567 B1 KR102013567 B1 KR 102013567B1
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polymorph
yloxy
isoquinolin
hydrochloride
piperidin
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KR20140046460A (ko
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노르베르트 나겔
브루노 바움가르터너
하랄트 베르흐톨트
올리버 플레텐부륵
디터 카데라이트
만디 모흐닉케
지몬 게쓸러
요아힘 틸너
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사노피
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
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KR1020147003355A 2011-07-08 2012-06-27 ６-(피페리딘-４-일옥시)-２ｈ-이소퀴놀린-１-온 하이드로클로라이드의 다형체 Active KR102013567B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11305891 2011-07-08
EP11305891.1 2011-07-08
EP11306034.7 2011-12-29
EP11306034 2011-12-29
PCT/EP2012/062444 WO2013007519A1 (en) 2011-07-08 2012-06-27 Polymorphs of 6-(piperidin-4-yloxy)-2h-isoquinolin-1-one hydrochloride

Publications (2)

Publication Number Publication Date
KR20140046460A KR20140046460A (ko) 2014-04-18
KR102013567B1 true KR102013567B1 (ko) 2019-08-23

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US (1) US8598201B2 (https=)
EP (1) EP2729461B1 (https=)
JP (1) JP2014518236A (https=)
KR (1) KR102013567B1 (https=)
CN (1) CN103781777A (https=)
AU (1) AU2012283277B2 (https=)
CA (1) CA2843777C (https=)
CY (1) CY1117545T1 (https=)
DK (1) DK2729461T3 (https=)
ES (1) ES2567317T3 (https=)
HR (1) HRP20160358T1 (https=)
HU (1) HUE028550T2 (https=)
IN (1) IN2014CN00834A (https=)
PL (1) PL2729461T3 (https=)
RU (1) RU2014104357A (https=)
SI (1) SI2729461T1 (https=)
WO (1) WO2013007519A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109810173B (zh) * 2017-11-21 2020-11-27 首都医科大学 二氢异喹啉-3-甲酰-TARGD(aa)aa,其制备,抗静脉血栓活性和应用
AU2023320331A1 (en) * 2022-08-01 2025-01-23 Valo Health, Inc. Process for preparing 6-substituted-1-(2h)-isoquinolinones and intermediate compound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077550A1 (en) * 2006-12-27 2008-07-03 Sanofi-Aventis Substituted isoquinoline and isoquinolinone derivatives as inhibitors of rho-kinase

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051919A2 (en) * 2000-01-07 2001-07-19 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
KR101373535B1 (ko) 2005-07-26 2014-03-12 사노피 Ｒｈｏ-키나제 억제제로서의 피페리디닐-치환된 이소퀴놀론유도체
TW200738682A (en) 2005-12-08 2007-10-16 Organon Nv Isoquinoline derivatives
CN101910123A (zh) * 2007-12-26 2010-12-08 塞诺菲-安万特股份有限公司 6-取代的-1-(2h)-异喹啉酮的制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077550A1 (en) * 2006-12-27 2008-07-03 Sanofi-Aventis Substituted isoquinoline and isoquinolinone derivatives as inhibitors of rho-kinase

Also Published As

Publication number Publication date
PL2729461T3 (pl) 2016-06-30
SI2729461T1 (sl) 2016-06-30
KR20140046460A (ko) 2014-04-18
HK1192234A1 (zh) 2014-08-15
WO2013007519A1 (en) 2013-01-17
AU2012283277A1 (en) 2014-02-27
EP2729461A1 (en) 2014-05-14
CA2843777C (en) 2018-11-06
RU2014104357A (ru) 2015-08-20
DK2729461T3 (en) 2016-04-11
US8598201B2 (en) 2013-12-03
HUE028550T2 (en) 2016-12-28
EP2729461B1 (en) 2016-01-20
AU2012283277B2 (en) 2016-07-21
CA2843777A1 (en) 2013-01-17
HRP20160358T1 (hr) 2016-05-06
CY1117545T1 (el) 2017-04-26
IN2014CN00834A (https=) 2015-04-03
US20130012479A1 (en) 2013-01-10
CN103781777A (zh) 2014-05-07
ES2567317T3 (es) 2016-04-21
JP2014518236A (ja) 2014-07-28

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