KR101966867B1 - 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올 - Google Patents

세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올 Download PDF

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KR101966867B1
KR101966867B1 KR1020177034637A KR20177034637A KR101966867B1 KR 101966867 B1 KR101966867 B1 KR 101966867B1 KR 1020177034637 A KR1020177034637 A KR 1020177034637A KR 20177034637 A KR20177034637 A KR 20177034637A KR 101966867 B1 KR101966867 B1 KR 101966867B1
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compound
bacterial
composition
antibiotic
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KR20170136009A (ko
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브렛 휴 제임스 베이커
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마이크로비온 코포레이션
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Priority claimed from PCT/US2010/023108 external-priority patent/WO2010091124A2/en
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Priority claimed from PCT/US2011/023549 external-priority patent/WO2011097347A2/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/82Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • A61K33/245Bismuth; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
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    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/54Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
KR1020177034637A 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올 KR101966867B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/US2010/023108 WO2010091124A2 (en) 2009-02-03 2010-02-03 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
WOPCT/US2010/023108 2010-02-03
US37318810P 2010-08-12 2010-08-12
US61/373,188 2010-08-12
PCT/US2011/023549 WO2011097347A2 (en) 2010-02-03 2011-02-03 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses

Related Parent Applications (1)

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KR1020127022562A Division KR101821833B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올

Related Child Applications (1)

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KR1020197009488A Division KR102074444B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올

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KR20170136009A KR20170136009A (ko) 2017-12-08
KR101966867B1 true KR101966867B1 (ko) 2019-04-08

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KR1020177034637A KR101966867B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020197009488A KR102074444B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020207003093A KR20200015814A (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020127022562A KR101821833B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020187019857A KR20180085042A (ko) 2010-08-12 2011-08-11 농업, 산업 및 다른 용도를 위한 방부제로서 비스무트-티올
KR1020137006121A KR20130132410A (ko) 2010-08-12 2011-08-11 농업, 산업 및 다른 용도를 위한 방부제로서 비스무트-티올

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KR1020197009488A KR102074444B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020207003093A KR20200015814A (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020127022562A KR101821833B1 (ko) 2010-02-03 2011-02-03 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
KR1020187019857A KR20180085042A (ko) 2010-08-12 2011-08-11 농업, 산업 및 다른 용도를 위한 방부제로서 비스무트-티올
KR1020137006121A KR20130132410A (ko) 2010-08-12 2011-08-11 농업, 산업 및 다른 용도를 위한 방부제로서 비스무트-티올

Country Status (16)

Country Link
EP (1) EP2603083A4 (es)
JP (7) JP2013535506A (es)
KR (6) KR101966867B1 (es)
CN (2) CN103096720B (es)
AU (3) AU2011289338B2 (es)
BR (2) BR112012019286A2 (es)
CA (1) CA2807993C (es)
CL (2) CL2013000430A1 (es)
IL (3) IL224684A (es)
MX (4) MX371047B (es)
NZ (1) NZ606634A (es)
PH (1) PH12016502498A1 (es)
RU (2) RU2013110493A (es)
SG (3) SG10201506131RA (es)
UA (1) UA113616C2 (es)
WO (1) WO2012021754A2 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021010595A1 (ko) * 2019-07-16 2021-01-21 주식회사 인트론바이오테크놀로지 신규한 엔테로박터 애로진스 박테리오파지 ent-aep-1 및 이의 엔테로박터 애로진스 균과 엔테로박터 클로아카 균 증식 억제 용도

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US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
EP3695835A1 (en) 2009-02-03 2020-08-19 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
KR101966867B1 (ko) * 2010-02-03 2019-04-08 마이크로비온 코포레이션 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
JP6392846B2 (ja) * 2013-03-18 2018-09-19 テラノーヴィス・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディトゲゼルシャフト 口腔ケア用組成物
RU2525200C1 (ru) * 2013-04-09 2014-08-10 Алексей Георгиевич Бородкин Средство для защиты и заживления ран деревьев
KR101703732B1 (ko) * 2013-11-07 2017-02-07 (주)아모레퍼시픽 효소처리 동백나무 씨 오일을 포함하는 항염 조성물
WO2017145142A1 (en) 2016-02-25 2017-08-31 Nobio Ltd. Micro and nanoparticulate compositions comprising anti-microbially active groups
US20190062528A1 (en) 2017-08-30 2019-02-28 Nobio Ltd. Compositions and medical devices comprising anti-microbial particles
CN107950536A (zh) * 2017-12-04 2018-04-24 刘志伟 一种含百菌清的杀菌组合物
CN108839186B (zh) * 2018-05-15 2021-02-26 阜南县金威工艺品有限公司 一种桑枝编织品防霉处理方法
KR20210084425A (ko) 2018-07-31 2021-07-07 마이크로비온 코포레이션 비스무트-티올 조성물 및 사용 방법
CN112788950A (zh) 2018-07-31 2021-05-11 微生物公司 用于治疗伤口的铋-硫醇组合物和方法
KR101990253B1 (ko) * 2018-11-22 2019-06-17 하봉호 컨테이너형 버섯재배장치
CN109997856B (zh) * 2019-04-15 2020-11-03 广西大学 一种小分子化合物的组合物及其应用
JP7458622B2 (ja) 2019-09-18 2024-04-01 学校法人東京農業大学 抗生物質耐性微生物の耐性を低下させる物質及び抗生物質耐性微生物の耐性を低下させる方法
CN110663672B (zh) * 2019-11-13 2024-04-26 南京林业大学 一种螺纹驱动的根部施药头
US11479655B2 (en) 2020-01-15 2022-10-25 The Boeing Company Compositions for use with polysulfide sealants and related methods
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CN111856546B (zh) * 2020-06-23 2022-07-29 中国辐射防护研究院 一种关于海洋生物灰中Cs-137放化分析的制样方法
CN113969300A (zh) * 2020-07-23 2022-01-25 启迪禾美生物科技(嘉兴)有限公司 一种桉树叶复合活性提取物工艺及其抗菌应用
CN112640907B (zh) * 2021-01-19 2021-11-16 西南大学 硫辛酸抑制植物真菌致病菌的新用途及防治柑橘果实采后真菌病害的方法
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