KR101937498B1 - 폐 질환 및 손상을 치료하기 위한 조성물 및 방법 - Google Patents

폐 질환 및 손상을 치료하기 위한 조성물 및 방법 Download PDF

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KR101937498B1
KR101937498B1 KR1020137025288A KR20137025288A KR101937498B1 KR 101937498 B1 KR101937498 B1 KR 101937498B1 KR 1020137025288 A KR1020137025288 A KR 1020137025288A KR 20137025288 A KR20137025288 A KR 20137025288A KR 101937498 B1 KR101937498 B1 KR 101937498B1
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sequence
tlr2
nucleic acid
nucleotides
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KR20140042792A (ko
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앤드류 이. 겔만
엘리나 페인스테인
스베틀라나 아담스키
이고르 메트
하가 칼린스키
샤론 아브킨-나훔
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쿠아크 파마수티칼스 인코퍼레이티드
워싱턴 유니버시티
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/34—Spatial arrangement of the modifications
    • C12N2310/344—Position-specific modifications, e.g. on every purine, at the 3'-end

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KR1020137025288A 2011-03-03 2012-03-01 폐 질환 및 손상을 치료하기 위한 조성물 및 방법 Expired - Fee Related KR101937498B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161448723P 2011-03-03 2011-03-03
US61/448,723 2011-03-03
PCT/US2012/027169 WO2012118910A2 (en) 2011-03-03 2012-03-01 Compositions and methods for treating lung disease and injury

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KR20140042792A KR20140042792A (ko) 2014-04-07
KR101937498B1 true KR101937498B1 (ko) 2019-04-10

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US (2) US9205100B2 (https=)
EP (1) EP2681314B1 (https=)
JP (1) JP6000287B2 (https=)
KR (1) KR101937498B1 (https=)
CN (1) CN103492572A (https=)
AU (1) AU2012223365B2 (https=)
CA (1) CA2828002A1 (https=)
IL (1) IL228252A (https=)
SG (1) SG192961A1 (https=)
WO (1) WO2012118910A2 (https=)

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ES2555160B1 (es) * 2014-06-24 2016-10-25 Aptus Biotech, S.L. Aptámeros específicos de TLR-4 y usos de los mismos
WO2017152073A1 (en) 2016-03-04 2017-09-08 University Of Louisville Research Foundation, Inc. Methods and compositions for ex vivo expansion of very small embryonic-like stem cells (vsels)
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WO2018191747A1 (en) 2017-04-14 2018-10-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating pulmonary arterial hypertension
CN110945128B (zh) * 2017-04-14 2023-11-03 代表亚利桑那大学的亚利桑那董事会 用于治疗肺纤维化的组合物和方法
WO2020011869A2 (en) 2018-07-11 2020-01-16 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides targeting tlr2
EP4073246A4 (en) * 2019-12-12 2023-12-06 President And Fellows Of Harvard College COMPOSITIONS AND METHODS FOR LIGHT-DIRECTED BIOMOLECULAR BARCODING
US11851707B1 (en) * 2020-03-27 2023-12-26 University Of South Florida N-Myc-Interactor protein as a marker for chronic lung disease and uses thereof
KR102562955B1 (ko) 2021-07-08 2023-08-03 렉스소프트 주식회사 폐 기능 저하 위험 예측용 단일염기다형성 및 이의 용도
CN114796273A (zh) * 2022-07-01 2022-07-29 中国人民解放军总医院第一医学中心 Tlr4激动的外泌体或外泌体制剂在制备防治放射性肺损伤药物中的应用

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