KR101932206B1 - 4-치환 이미다졸의 신규 제조방법 - Google Patents
4-치환 이미다졸의 신규 제조방법 Download PDFInfo
- Publication number
- KR101932206B1 KR101932206B1 KR1020147004568A KR20147004568A KR101932206B1 KR 101932206 B1 KR101932206 B1 KR 101932206B1 KR 1020147004568 A KR1020147004568 A KR 1020147004568A KR 20147004568 A KR20147004568 A KR 20147004568A KR 101932206 B1 KR101932206 B1 KR 101932206B1
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- KR
- South Korea
- Prior art keywords
- formula
- compound
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 Cc1c(C)c(B(O*)O*)ccc1 Chemical compound Cc1c(C)c(B(O*)O*)ccc1 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
- C07C47/105—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings
- C07C47/11—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161510538P | 2011-07-22 | 2011-07-22 | |
| US61/510,538 | 2011-07-22 | ||
| PCT/GB2012/051746 WO2013014428A1 (en) | 2011-07-22 | 2012-07-20 | New processes for preparing 4-substituted imidazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140068888A KR20140068888A (ko) | 2014-06-09 |
| KR101932206B1 true KR101932206B1 (ko) | 2018-12-24 |
Family
ID=46939718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147004568A Active KR101932206B1 (ko) | 2011-07-22 | 2012-07-20 | 4-치환 이미다졸의 신규 제조방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8962862B2 (enExample) |
| EP (1) | EP2734508B1 (enExample) |
| JP (1) | JP5996647B2 (enExample) |
| KR (1) | KR101932206B1 (enExample) |
| CN (1) | CN103748077B (enExample) |
| DK (1) | DK2734508T3 (enExample) |
| ES (1) | ES2665093T3 (enExample) |
| HR (1) | HRP20180397T1 (enExample) |
| HU (1) | HUE037591T2 (enExample) |
| IN (1) | IN2014DN00144A (enExample) |
| NO (1) | NO2650436T3 (enExample) |
| PL (1) | PL2734508T3 (enExample) |
| WO (1) | WO2013014428A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103588711B (zh) | 2013-11-27 | 2015-04-08 | 天津炜捷制药有限公司 | 一种美托咪定中间体的制备方法 |
| GB201501593D0 (en) * | 2015-01-30 | 2015-03-18 | Cambrex Karlskoga Ab | New compounds and processes |
| KR101940662B1 (ko) | 2017-08-11 | 2019-01-22 | 충남대학교산학협력단 | 직류전원 공급부를 가지는 산화제 과잉환경 시험장치 |
| KR101940663B1 (ko) | 2017-08-11 | 2019-01-22 | 충남대학교산학협력단 | 촉매 반응부를 가지는 산화제 과잉 시험장치 |
| US12050293B2 (en) | 2018-12-19 | 2024-07-30 | Pgs Geophysical As | Medetomidine compositions having improved anti-fouling characteristics |
| CN118772061A (zh) | 2020-10-21 | 2024-10-15 | I-技术有限公司 | 防污化合物 |
| CN117295718A (zh) | 2022-03-22 | 2023-12-26 | 维科-兹多洛夫希沃特尼赫有限责任公司 | 美托咪定及其衍生物的制备方法 |
| EP4580398A1 (en) | 2022-09-01 | 2025-07-09 | I-Tech AB | Composition protecting wood against marine woodborers |
| CN115745893A (zh) * | 2022-11-16 | 2023-03-07 | 西安近代化学研究所 | 一种合成2-氰基-5-芳基-1h-咪唑类化合物的方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506044A (ja) | 2000-08-17 | 2004-02-26 | ファイザー・インク | ＴＡＦＩａ阻害剤としての置換されたイミダゾール |
| JP2010527987A (ja) | 2007-05-24 | 2010-08-19 | エルドラッグ エス．エイ． | １，（３，）５−置換イミダゾール類、高血圧症の治療でのそれらの使用及びそれらの調製方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2016809C3 (de) * | 1969-04-10 | 1974-05-16 | S.A. Prb, Bruessel | Verfahren zur Herstellung von Arylierungsprodukten olefinisch ungesättigter Verbindungen |
| GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
| EP1918282A1 (en) | 2006-11-06 | 2008-05-07 | "Joint Stock Company Grindeks" | Method for preparing medetomidine and its salts |
| GB2453982B (en) | 2007-10-24 | 2009-09-16 | Norbrook Lab Ltd | Chemical process for the preparation of Medetomidine |
| CN101921234B (zh) | 2009-06-12 | 2012-05-30 | 中国中化股份有限公司 | 一种制备美托咪啶的方法 |
| WO2011070069A1 (en) | 2009-12-09 | 2011-06-16 | I-Tech Ab | Process for preparation of medetomidine |
-
2012
- 2012-07-20 JP JP2014522149A patent/JP5996647B2/ja active Active
- 2012-07-20 KR KR1020147004568A patent/KR101932206B1/ko active Active
- 2012-07-20 US US14/234,263 patent/US8962862B2/en active Active
- 2012-07-20 CN CN201280035891.3A patent/CN103748077B/zh active Active
- 2012-07-20 IN IN144DEN2014 patent/IN2014DN00144A/en unknown
- 2012-07-20 ES ES12766318.5T patent/ES2665093T3/es active Active
- 2012-07-20 WO PCT/GB2012/051746 patent/WO2013014428A1/en not_active Ceased
- 2012-07-20 DK DK12766318.5T patent/DK2734508T3/en active
- 2012-07-20 HU HUE12766318A patent/HUE037591T2/hu unknown
- 2012-07-20 HR HRP20180397TT patent/HRP20180397T1/hr unknown
- 2012-07-20 PL PL12766318T patent/PL2734508T3/pl unknown
- 2012-07-20 EP EP12766318.5A patent/EP2734508B1/en active Active
-
2013
- 2013-01-26 NO NO13000388A patent/NO2650436T3/no unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506044A (ja) | 2000-08-17 | 2004-02-26 | ファイザー・インク | ＴＡＦＩａ阻害剤としての置換されたイミダゾール |
| JP2010527987A (ja) | 2007-05-24 | 2010-08-19 | エルドラッグ エス．エイ． | １，（３，）５−置換イミダゾール類、高血圧症の治療でのそれらの使用及びそれらの調製方法 |
Non-Patent Citations (1)
| Title |
|---|
| Nano-Fe2O3-catalyzed direct borylation of arenes, Chem. Commun., 2010, 46, 3170-3172 |
Also Published As
| Publication number | Publication date |
|---|---|
| PL2734508T3 (pl) | 2018-08-31 |
| CN103748077B (zh) | 2016-08-17 |
| DK2734508T3 (en) | 2018-05-22 |
| US8962862B2 (en) | 2015-02-24 |
| US20140187789A1 (en) | 2014-07-03 |
| EP2734508A1 (en) | 2014-05-28 |
| HRP20180397T1 (hr) | 2018-05-18 |
| HUE037591T2 (hu) | 2018-09-28 |
| CN103748077A (zh) | 2014-04-23 |
| ES2665093T3 (es) | 2018-04-24 |
| JP2014520901A (ja) | 2014-08-25 |
| WO2013014428A1 (en) | 2013-01-31 |
| JP5996647B2 (ja) | 2016-09-21 |
| NO2650436T3 (enExample) | 2018-03-10 |
| IN2014DN00144A (enExample) | 2015-05-22 |
| EP2734508B1 (en) | 2018-02-28 |
| KR20140068888A (ko) | 2014-06-09 |
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St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
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St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
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