KR101896820B1 - 페나지늄 매개체 - Google Patents
페나지늄 매개체 Download PDFInfo
- Publication number
- KR101896820B1 KR101896820B1 KR1020167028460A KR20167028460A KR101896820B1 KR 101896820 B1 KR101896820 B1 KR 101896820B1 KR 1020167028460 A KR1020167028460 A KR 1020167028460A KR 20167028460 A KR20167028460 A KR 20167028460A KR 101896820 B1 KR101896820 B1 KR 101896820B1
- Authority
- KR
- South Korea
- Prior art keywords
- chemical
- chemical compound
- test
- analyte
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- BQKHAUGELDEHNN-UHFFFAOYSA-O CC[NH+]1c2ccccc2N=C2C(NC(CCC(O)=O)=O)=CC=CC12 Chemical compound CC[NH+]1c2ccccc2N=C2C(NC(CCC(O)=O)=O)=CC=CC12 BQKHAUGELDEHNN-UHFFFAOYSA-O 0.000 description 1
- QYFIFZPWQATOJL-UHFFFAOYSA-O CC[n+]1c(cccc2)c2nc2c1cccc2NC(CCC(OC)=O)=O Chemical compound CC[n+]1c(cccc2)c2nc2c1cccc2NC(CCC(OC)=O)=O QYFIFZPWQATOJL-UHFFFAOYSA-O 0.000 description 1
- 0 COC(CCC(*c1cccc2nc(cccc3)c3nc12)=O)=O Chemical compound COC(CCC(*c1cccc2nc(cccc3)c3nc12)=O)=O 0.000 description 1
- SRXOJMOGPYFZKC-UHFFFAOYSA-N COC(CCC(Cl)=O)=O Chemical compound COC(CCC(Cl)=O)=O SRXOJMOGPYFZKC-UHFFFAOYSA-N 0.000 description 1
- QWUFXJHVFNRNCU-UHFFFAOYSA-N Nc1cccc2c1nc(cccc1)c1n2 Chemical compound Nc1cccc2c1nc(cccc1)c1n2 QWUFXJHVFNRNCU-UHFFFAOYSA-N 0.000 description 1
- SZPYAECITOLLCR-UHFFFAOYSA-N OCNc1cccc2nc3ccccc3nc12 Chemical compound OCNc1cccc2nc3ccccc3nc12 SZPYAECITOLLCR-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/46—Phenazines
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
- G01D21/00—Measuring or testing not otherwise provided for
- G01D21/02—Measuring two or more variables by means not covered by a single other subclass
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14164571 | 2014-04-14 | ||
| EP14164571.3 | 2014-04-14 | ||
| PCT/EP2015/057933 WO2015158645A1 (en) | 2014-04-14 | 2015-04-13 | Phenazinium mediators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20160132970A KR20160132970A (ko) | 2016-11-21 |
| KR101896820B1 true KR101896820B1 (ko) | 2018-09-07 |
Family
ID=50478330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167028460A Active KR101896820B1 (ko) | 2014-04-14 | 2015-04-13 | 페나지늄 매개체 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9988358B2 (enExample) |
| EP (1) | EP3131882B1 (enExample) |
| JP (1) | JP6522003B2 (enExample) |
| KR (1) | KR101896820B1 (enExample) |
| CN (1) | CN106164054B (enExample) |
| CA (1) | CA2945612C (enExample) |
| WO (1) | WO2015158645A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3523639T3 (pl) | 2016-10-05 | 2025-03-17 | F. Hoffmann-La Roche Ag | Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania |
| CN111936050A (zh) | 2018-03-30 | 2020-11-13 | 普和希控股公司 | 使用吩嗪衍生物或含有吩嗪衍生物的高分子量氧化还原聚合物的传感器 |
| JP7285332B2 (ja) * | 2019-09-30 | 2023-06-01 | Phcホールディングス株式会社 | 高分子量レドックスポリマー及びそれを用いたバイオセンサ |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683198A (en) | 1983-11-22 | 1987-07-28 | Toyo Jozo Kabushiki Kaisha | Novel maltose dehydrogenase, process for its production, and analytical method using the same |
| KR101223854B1 (ko) | 2008-03-27 | 2013-01-18 | 에프. 호프만-라 로슈 아게 | 분석물 특이성이 개선된 바이오센서 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3228542A1 (de) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zur bestimmung der konzentration elektrochemisch umsetzbarer stoffe |
| US5108564A (en) | 1988-03-15 | 1992-04-28 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
| US5054039A (en) | 1990-08-30 | 1991-10-01 | The United States Of America As Represented By The Secretary Of The Navy | Digital calibration circuit employing composite sine wave signals |
| DE19629656A1 (de) | 1996-07-23 | 1998-01-29 | Boehringer Mannheim Gmbh | Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe |
| US5801006A (en) | 1997-02-04 | 1998-09-01 | Specialty Assays, Inc. | Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites |
| JP4070050B2 (ja) | 1998-07-24 | 2008-04-02 | テルモ株式会社 | 血糖値測定方法及び装置 |
| US6380380B1 (en) | 1999-01-04 | 2002-04-30 | Specialty Assays, Inc. | Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates |
| WO2002034919A1 (en) | 2000-10-27 | 2002-05-02 | Roche Diagnostics Gmbh | Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase |
| US7867369B2 (en) | 2003-06-20 | 2011-01-11 | Roche Diagnostics Operations, Inc. | Biosensor with multiple electrical functionalities |
| MXPA06001719A (es) | 2003-08-11 | 2006-05-19 | Codexis Inc | Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados. |
| DE102005035461A1 (de) | 2005-07-28 | 2007-02-15 | Roche Diagnostics Gmbh | Stabile NAD/NADH-Derivate |
| DE502006004037D1 (de) | 2005-12-19 | 2009-07-30 | Roche Diagnostics Gmbh | Sandwichsensor zur ermittlung einer analytkonzentration |
| EP2093284A1 (de) | 2008-02-19 | 2009-08-26 | F.Hoffmann-La Roche Ag | Stabilisierung von Dehydrogenasen mit stabilen Coenzymen |
| EP3838147B1 (en) | 2012-06-29 | 2023-12-06 | Roche Diabetes Care GmbH | Sensor element for detecting an analyte in a body fluid |
| JP2014194411A (ja) * | 2013-02-28 | 2014-10-09 | Aisin Seiki Co Ltd | 修飾電極、当該修飾電極の製造方法、当該修飾電極を備えるバイオ電池並びにバイオセンサー |
| CN111848578B (zh) * | 2014-08-22 | 2023-10-31 | 豪夫迈·罗氏有限公司 | 氧化还原指示剂 |
-
2015
- 2015-04-13 CN CN201580019437.2A patent/CN106164054B/zh active Active
- 2015-04-13 KR KR1020167028460A patent/KR101896820B1/ko active Active
- 2015-04-13 EP EP15718466.4A patent/EP3131882B1/en active Active
- 2015-04-13 JP JP2016559436A patent/JP6522003B2/ja active Active
- 2015-04-13 CA CA2945612A patent/CA2945612C/en not_active Expired - Fee Related
- 2015-04-13 WO PCT/EP2015/057933 patent/WO2015158645A1/en not_active Ceased
-
2016
- 2016-10-11 US US15/290,440 patent/US9988358B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683198A (en) | 1983-11-22 | 1987-07-28 | Toyo Jozo Kabushiki Kaisha | Novel maltose dehydrogenase, process for its production, and analytical method using the same |
| KR101223854B1 (ko) | 2008-03-27 | 2013-01-18 | 에프. 호프만-라 로슈 아게 | 분석물 특이성이 개선된 바이오센서 |
Non-Patent Citations (1)
| Title |
|---|
| H. BUENEMANN et al. Biochemistry, 1981, Vol. 20, No. 10, pp. 2864-2874. |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3131882A1 (en) | 2017-02-22 |
| KR20160132970A (ko) | 2016-11-21 |
| US9988358B2 (en) | 2018-06-05 |
| JP2017517480A (ja) | 2017-06-29 |
| CA2945612C (en) | 2019-09-10 |
| EP3131882B1 (en) | 2020-07-15 |
| JP6522003B2 (ja) | 2019-05-29 |
| US20170226068A1 (en) | 2017-08-10 |
| CN106164054B (zh) | 2019-05-07 |
| CA2945612A1 (en) | 2015-10-22 |
| CN106164054A (zh) | 2016-11-23 |
| WO2015158645A1 (en) | 2015-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| AMND | Amendment | ||
| PA0105 | International application |
Patent event date: 20161013 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20161013 Comment text: Request for Examination of Application |
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| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20170919 Patent event code: PE09021S01D |
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| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20180328 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20170919 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
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Patent event code: PX09011S01I Patent event date: 20180328 Comment text: Decision to Refuse Application Patent event code: PX09012R01I Patent event date: 20171120 Comment text: Amendment to Specification, etc. Patent event code: PX09012R01I Patent event date: 20161013 Comment text: Amendment to Specification, etc. |
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| X701 | Decision to grant (after re-examination) | ||
| GRNT | Written decision to grant | ||
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