KR101896820B1 - 페나지늄 매개체 - Google Patents

페나지늄 매개체 Download PDF

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KR101896820B1
KR101896820B1 KR1020167028460A KR20167028460A KR101896820B1 KR 101896820 B1 KR101896820 B1 KR 101896820B1 KR 1020167028460 A KR1020167028460 A KR 1020167028460A KR 20167028460 A KR20167028460 A KR 20167028460A KR 101896820 B1 KR101896820 B1 KR 101896820B1
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chemical
chemical compound
test
analyte
sample
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KR20160132970A (ko
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디터 하인들
크리슈티네 노르트마이어
페터 게바우어
듀 발 스테이시 헌트
클라우스 안드레아스 바우어-에스핀돌라
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에프. 호프만-라 로슈 아게
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46Phenazines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D21/00Measuring or testing not otherwise provided for
    • G01D21/02Measuring two or more variables by means not covered by a single other subclass
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020167028460A 2014-04-14 2015-04-13 페나지늄 매개체 Active KR101896820B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14164571 2014-04-14
EP14164571.3 2014-04-14
PCT/EP2015/057933 WO2015158645A1 (en) 2014-04-14 2015-04-13 Phenazinium mediators

Publications (2)

Publication Number Publication Date
KR20160132970A KR20160132970A (ko) 2016-11-21
KR101896820B1 true KR101896820B1 (ko) 2018-09-07

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KR1020167028460A Active KR101896820B1 (ko) 2014-04-14 2015-04-13 페나지늄 매개체

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US (1) US9988358B2 (enExample)
EP (1) EP3131882B1 (enExample)
JP (1) JP6522003B2 (enExample)
KR (1) KR101896820B1 (enExample)
CN (1) CN106164054B (enExample)
CA (1) CA2945612C (enExample)
WO (1) WO2015158645A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3523639T3 (pl) 2016-10-05 2025-03-17 F. Hoffmann-La Roche Ag Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania
CN111936050A (zh) 2018-03-30 2020-11-13 普和希控股公司 使用吩嗪衍生物或含有吩嗪衍生物的高分子量氧化还原聚合物的传感器
JP7285332B2 (ja) * 2019-09-30 2023-06-01 Phcホールディングス株式会社 高分子量レドックスポリマー及びそれを用いたバイオセンサ

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683198A (en) 1983-11-22 1987-07-28 Toyo Jozo Kabushiki Kaisha Novel maltose dehydrogenase, process for its production, and analytical method using the same
KR101223854B1 (ko) 2008-03-27 2013-01-18 에프. 호프만-라 로슈 아게 분석물 특이성이 개선된 바이오센서

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3228542A1 (de) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der konzentration elektrochemisch umsetzbarer stoffe
US5108564A (en) 1988-03-15 1992-04-28 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
US5054039A (en) 1990-08-30 1991-10-01 The United States Of America As Represented By The Secretary Of The Navy Digital calibration circuit employing composite sine wave signals
DE19629656A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
JP4070050B2 (ja) 1998-07-24 2008-04-02 テルモ株式会社 血糖値測定方法及び装置
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
WO2002034919A1 (en) 2000-10-27 2002-05-02 Roche Diagnostics Gmbh Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase
US7867369B2 (en) 2003-06-20 2011-01-11 Roche Diagnostics Operations, Inc. Biosensor with multiple electrical functionalities
MXPA06001719A (es) 2003-08-11 2006-05-19 Codexis Inc Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados.
DE102005035461A1 (de) 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
DE502006004037D1 (de) 2005-12-19 2009-07-30 Roche Diagnostics Gmbh Sandwichsensor zur ermittlung einer analytkonzentration
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP3838147B1 (en) 2012-06-29 2023-12-06 Roche Diabetes Care GmbH Sensor element for detecting an analyte in a body fluid
JP2014194411A (ja) * 2013-02-28 2014-10-09 Aisin Seiki Co Ltd 修飾電極、当該修飾電極の製造方法、当該修飾電極を備えるバイオ電池並びにバイオセンサー
CN111848578B (zh) * 2014-08-22 2023-10-31 豪夫迈·罗氏有限公司 氧化还原指示剂

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683198A (en) 1983-11-22 1987-07-28 Toyo Jozo Kabushiki Kaisha Novel maltose dehydrogenase, process for its production, and analytical method using the same
KR101223854B1 (ko) 2008-03-27 2013-01-18 에프. 호프만-라 로슈 아게 분석물 특이성이 개선된 바이오센서

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H. BUENEMANN et al. Biochemistry, 1981, Vol. 20, No. 10, pp. 2864-2874.

Also Published As

Publication number Publication date
EP3131882A1 (en) 2017-02-22
KR20160132970A (ko) 2016-11-21
US9988358B2 (en) 2018-06-05
JP2017517480A (ja) 2017-06-29
CA2945612C (en) 2019-09-10
EP3131882B1 (en) 2020-07-15
JP6522003B2 (ja) 2019-05-29
US20170226068A1 (en) 2017-08-10
CN106164054B (zh) 2019-05-07
CA2945612A1 (en) 2015-10-22
CN106164054A (zh) 2016-11-23
WO2015158645A1 (en) 2015-10-22

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