KR101865420B1 - 벡터적 이온 채널의 조절을 위한 유기화합물 - Google Patents

벡터적 이온 채널의 조절을 위한 유기화합물 Download PDF

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KR101865420B1
KR101865420B1 KR1020127018445A KR20127018445A KR101865420B1 KR 101865420 B1 KR101865420 B1 KR 101865420B1 KR 1020127018445 A KR1020127018445 A KR 1020127018445A KR 20127018445 A KR20127018445 A KR 20127018445A KR 101865420 B1 KR101865420 B1 KR 101865420B1
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South Korea
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amino
seq
amino acid
terminal
treatment
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KR1020127018445A
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English (en)
Korean (ko)
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KR20120134100A (ko
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베른하드 피셔
루돌프 루카스
수잔 조조스
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아펩티코 포어슝 운트 엔트빅크룽 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127018445A 2010-01-14 2011-01-12 벡터적 이온 채널의 조절을 위한 유기화합물 KR101865420B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0004110A AT509267A1 (de) 2010-01-14 2010-01-14 Organische verbindungen zur regulierung von vektoriellen ionenkanälen
ATA41/2010 2010-01-14
PCT/AT2011/000014 WO2011085423A1 (de) 2010-01-14 2011-01-12 Zyklische peptide zur regulierung von vektoriellen ionenkanälen

Publications (2)

Publication Number Publication Date
KR20120134100A KR20120134100A (ko) 2012-12-11
KR101865420B1 true KR101865420B1 (ko) 2018-07-13

Family

ID=43970939

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127018445A KR101865420B1 (ko) 2010-01-14 2011-01-12 벡터적 이온 채널의 조절을 위한 유기화합물

Country Status (17)

Country Link
US (1) US8754049B2 (es)
EP (1) EP2523968B1 (es)
JP (1) JP5771220B2 (es)
KR (1) KR101865420B1 (es)
CN (1) CN102770442B (es)
AT (1) AT509267A1 (es)
AU (1) AU2011206907B2 (es)
BR (1) BR112012017093A2 (es)
CA (1) CA2785185C (es)
DK (1) DK2523968T3 (es)
ES (1) ES2525381T3 (es)
HK (1) HK1174341A1 (es)
IL (1) IL220924B (es)
NZ (1) NZ600818A (es)
PL (1) PL2523968T3 (es)
RU (1) RU2538597C2 (es)
WO (1) WO2011085423A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
WO2014173843A1 (en) 2013-04-23 2014-10-30 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula x1 -gqretpegaeakpwy-x2 and use for extracorporeal lung treatment
CN105188734B (zh) * 2013-04-23 2019-03-01 阿佩普蒂科研究和开发有限责任公司 含有式x1-gqretpegaeakpwy-x2的环肽的冻干物
KR20230038600A (ko) * 2014-03-04 2023-03-20 아펩티코 포어슝 운트 엔트빅크룽 게엠베하 폐내 염증의 완화
IL258067B (en) * 2015-09-14 2022-08-01 Apeptico Forschung & Entwicklung Gmbh Circular protein for the treatment of pha type 1b

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2009073909A1 (de) * 2007-12-12 2009-06-18 Apeptico Forschung Und Entwicklung Gmbh Zyklisches, cystein-freies protein

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US6017719A (en) * 1994-06-14 2000-01-25 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
TR200100338T2 (tr) 1998-08-14 2001-12-21 Innogenetics N.V. Ödem tedavisinde kullanılan TNF-türevleri peptitler.
FR2839514A1 (fr) * 2002-05-07 2003-11-14 Centre Nat Rech Scient Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens
ES2339954T3 (es) * 2004-08-06 2010-05-27 Nycomed Gmbh Composicion que comprende un agente tensioactivo pulmonar y un peptido derivado de tnf.
CN101003520A (zh) * 2007-01-12 2007-07-25 陈志龙 一种缬氨酸丁酰联苯化合物
CN101007791A (zh) * 2007-01-12 2007-08-01 东华大学 一种氨基酸联苯化合物
US8207295B2 (en) * 2008-06-04 2012-06-26 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2009023A1 (en) 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
AT506151B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Fusionsprotein
CN101298432B (zh) * 2008-05-30 2010-12-22 广州市星业科技发展有限公司 L-吡咯烷酮羧酸钠的制备方法
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
DK2397151T3 (en) * 2010-06-21 2015-05-18 Apeptico Forschung & Entwicklung Gmbh The treatment of the vascular complications of diabetes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073909A1 (de) * 2007-12-12 2009-06-18 Apeptico Forschung Und Entwicklung Gmbh Zyklisches, cystein-freies protein

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
국제공개공보 WO2009/073909(2009.06.18.) 1부. *

Also Published As

Publication number Publication date
ES2525381T3 (es) 2014-12-23
DK2523968T3 (da) 2014-11-03
AU2011206907A1 (en) 2012-06-21
CN102770442A (zh) 2012-11-07
AU2011206907B2 (en) 2016-06-02
JP2013517224A (ja) 2013-05-16
RU2538597C2 (ru) 2015-01-10
NZ600818A (en) 2014-02-28
PL2523968T3 (pl) 2015-03-31
EP2523968A1 (de) 2012-11-21
EP2523968B1 (de) 2014-09-10
CA2785185C (en) 2019-02-19
CN102770442B (zh) 2015-09-23
RU2012134322A (ru) 2014-02-20
KR20120134100A (ko) 2012-12-11
JP5771220B2 (ja) 2015-08-26
HK1174341A1 (en) 2013-06-07
US20130072444A1 (en) 2013-03-21
AT509267A1 (de) 2011-07-15
CA2785185A1 (en) 2011-07-21
WO2011085423A1 (de) 2011-07-21
BR112012017093A2 (pt) 2016-11-29
IL220924B (en) 2018-04-30
US8754049B2 (en) 2014-06-17

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