KR101849703B1 - 간질의 치료에서 파이토칸나비노이드 칸나비디바린(cbdv)의 용도 - Google Patents

간질의 치료에서 파이토칸나비노이드 칸나비디바린(cbdv)의 용도 Download PDF

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KR101849703B1
KR101849703B1 KR1020127028091A KR20127028091A KR101849703B1 KR 101849703 B1 KR101849703 B1 KR 101849703B1 KR 1020127028091 A KR1020127028091 A KR 1020127028091A KR 20127028091 A KR20127028091 A KR 20127028091A KR 101849703 B1 KR101849703 B1 KR 101849703B1
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cbdv
seizures
thcv
seizure
bds
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KR20130065646A (ko
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벤자민 웰리
클레어 윌리암스
게리 스티븐스
타카시 후타무라
힐 토마스
Original Assignee
지더블유 파마 리미티드
오쓰까 세이야꾸 가부시키가이샤
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Priority claimed from GB1005364.3A external-priority patent/GB2479153B/en
Priority claimed from GB1100042.9A external-priority patent/GB2487183B/en
Application filed by 지더블유 파마 리미티드, 오쓰까 세이야꾸 가부시키가이샤 filed Critical 지더블유 파마 리미티드
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Assigned to 지더블유 파마 리미티드 reassignment 지더블유 파마 리미티드 권리지분의 전부이전등록 Assignors: 오츠카 세이야쿠 가부시키가이샤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3482Cannabis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127028091A 2010-03-30 2011-03-30 간질의 치료에서 파이토칸나비노이드 칸나비디바린(cbdv)의 용도 Active KR101849703B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1005364.3A GB2479153B (en) 2010-03-30 2010-03-30 The phytocannabinoid cannabidivarin (CBDV) for use in the treatment of epilepsy
GB1005364.3 2010-03-30
GB1100042.9A GB2487183B (en) 2011-01-04 2011-01-04 Use of the phytocannabinoid cannabidivarin (CBDV) in the treatment of epilepsy
GB1100042.9 2011-01-04
PCT/GB2011/050649 WO2011121351A1 (en) 2010-03-30 2011-03-30 Use of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy

Publications (2)

Publication Number Publication Date
KR20130065646A KR20130065646A (ko) 2013-06-19
KR101849703B1 true KR101849703B1 (ko) 2018-04-17

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KR1020127028091A Active KR101849703B1 (ko) 2010-03-30 2011-03-30 간질의 치료에서 파이토칸나비노이드 칸나비디바린(cbdv)의 용도

Country Status (19)

Country Link
US (3) US9125859B2 (https=)
EP (2) EP3763361B1 (https=)
JP (1) JP5918748B2 (https=)
KR (1) KR101849703B1 (https=)
CN (1) CN103025325B (https=)
AR (1) AR080730A1 (https=)
AU (3) AU2011234225B2 (https=)
BR (1) BR112012024480A8 (https=)
CA (1) CA2794620C (https=)
EA (1) EA036044B1 (https=)
IL (1) IL222132B (https=)
MX (1) MX2012011033A (https=)
MY (1) MY162129A (https=)
NZ (1) NZ602925A (https=)
PH (1) PH12012501902A1 (https=)
SG (2) SG184236A1 (https=)
TW (1) TWI583374B (https=)
WO (1) WO2011121351A1 (https=)
ZA (1) ZA201208141B (https=)

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US20150320698A1 (en) 2015-11-12
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EA036044B1 (ru) 2020-09-17
EP3763361B1 (en) 2024-06-26
PH12012501902A1 (en) 2012-12-01
AU2011234225A1 (en) 2012-11-08
US20120004251A1 (en) 2012-01-05
AR080730A1 (es) 2012-05-02
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MY162129A (en) 2017-05-31
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US20210100755A1 (en) 2021-04-08
TW201138759A (en) 2011-11-16
AU2016244223A1 (en) 2016-11-03
BR112012024480A2 (pt) 2016-05-31
WO2011121351A1 (en) 2011-10-06
BR112012024480A8 (pt) 2018-04-03
US9125859B2 (en) 2015-09-08
EA201290975A8 (ru) 2017-02-28
KR20130065646A (ko) 2013-06-19
EP2552430A1 (en) 2013-02-06
AU2018217303A1 (en) 2018-09-06
CA2794620A1 (en) 2011-10-06
NZ602925A (en) 2014-11-28
IL222132B (en) 2018-04-30
SG184236A1 (en) 2012-10-30
CN103025325A (zh) 2013-04-03
US10799467B2 (en) 2020-10-13
JP2013523708A (ja) 2013-06-17
CA2794620C (en) 2018-03-13
CN103025325B (zh) 2016-03-16
EA201290975A1 (ru) 2013-04-30
US12023305B2 (en) 2024-07-02
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MX2012011033A (es) 2013-02-26
ZA201208141B (en) 2013-06-26

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