BR112012024480A2 - uso de fitocanabinóides canabidivarina (cbdv) no tratamento da epilepsia - Google Patents
uso de fitocanabinóides canabidivarina (cbdv) no tratamento da epilepsiaInfo
- Publication number
- BR112012024480A2 BR112012024480A2 BR112012024480A BR112012024480A BR112012024480A2 BR 112012024480 A2 BR112012024480 A2 BR 112012024480A2 BR 112012024480 A BR112012024480 A BR 112012024480A BR 112012024480 A BR112012024480 A BR 112012024480A BR 112012024480 A2 BR112012024480 A2 BR 112012024480A2
- Authority
- BR
- Brazil
- Prior art keywords
- cbdv
- epilepsy
- treatment
- phytocannabinoid
- cannabidivarine
- Prior art date
Links
- REOZWEGFPHTFEI-JKSUJKDBSA-N Cannabidivarin Chemical compound OC1=CC(CCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 REOZWEGFPHTFEI-JKSUJKDBSA-N 0.000 title abstract 3
- 206010015037 epilepsy Diseases 0.000 title abstract 3
- REOZWEGFPHTFEI-UHFFFAOYSA-N cannabidivarine Natural products OC1=CC(CCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 REOZWEGFPHTFEI-UHFFFAOYSA-N 0.000 title abstract 2
- ZROLHBHDLIHEMS-HUUCEWRRSA-N (6ar,10ar)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCC)=CC(O)=C3[C@@H]21 ZROLHBHDLIHEMS-HUUCEWRRSA-N 0.000 abstract 1
- ZROLHBHDLIHEMS-UHFFFAOYSA-N Delta9 tetrahydrocannabivarin Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCC)=CC(O)=C3C21 ZROLHBHDLIHEMS-UHFFFAOYSA-N 0.000 abstract 1
- 230000003556 anti-epileptic effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- HAPOVYFOVVWLRS-UHFFFAOYSA-N ethosuximide Chemical compound CCC1(C)CC(=O)NC1=O HAPOVYFOVVWLRS-UHFFFAOYSA-N 0.000 abstract 1
- 229960002767 ethosuximide Drugs 0.000 abstract 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 abstract 1
- 229960002695 phenobarbital Drugs 0.000 abstract 1
- AEQFSUDEHCCHBT-UHFFFAOYSA-M sodium valproate Chemical compound [Na+].CCCC(C([O-])=O)CCC AEQFSUDEHCCHBT-UHFFFAOYSA-M 0.000 abstract 1
- 229940102566 valproate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
uso de cannabidivarin fitocanabinoide (cbdv) no tratamento da epilepsia. esta invenção relaciona-se com a utilização do cannabidivarin fitocanabinoide (cbdv), e combinações do fitocanabinoide cbdv com tetrahydrocannabivarin (thcv) e canabidiol (cbd) no tratamento da epilepsia. a invenção diz ainda respeito à utilização do fitocanabinoide cbdv em combinação com o padrão anti-epilépticos (saeds). de preferência, o saed é um dos etossuximida, valproato oufenobarbital.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1005364.3A GB2479153B (en) | 2010-03-30 | 2010-03-30 | The phytocannabinoid cannabidivarin (CBDV) for use in the treatment of epilepsy |
GB1100042.9A GB2487183B (en) | 2011-01-04 | 2011-01-04 | Use of the phytocannabinoid cannabidivarin (CBDV) in the treatment of epilepsy |
PCT/GB2011/050649 WO2011121351A1 (en) | 2010-03-30 | 2011-03-30 | Use of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112012024480A2 true BR112012024480A2 (pt) | 2016-05-31 |
BR112012024480A8 BR112012024480A8 (pt) | 2018-04-03 |
Family
ID=43983229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012024480A BR112012024480A8 (pt) | 2010-03-30 | 2011-03-30 | Uso de fitocanabinóides canabidivarina (cbdv) no tratamento da epilepsia |
Country Status (18)
Country | Link |
---|---|
US (3) | US9125859B2 (pt) |
EP (2) | EP3763361A1 (pt) |
JP (1) | JP5918748B2 (pt) |
KR (1) | KR101849703B1 (pt) |
CN (1) | CN103025325B (pt) |
AR (1) | AR080730A1 (pt) |
AU (3) | AU2011234225B2 (pt) |
BR (1) | BR112012024480A8 (pt) |
CA (1) | CA2794620C (pt) |
EA (1) | EA036044B1 (pt) |
IL (1) | IL222132B (pt) |
MX (1) | MX2012011033A (pt) |
MY (1) | MY162129A (pt) |
NZ (1) | NZ602925A (pt) |
SG (2) | SG10201502480XA (pt) |
TW (1) | TWI583374B (pt) |
WO (1) | WO2011121351A1 (pt) |
ZA (1) | ZA201208141B (pt) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0425248D0 (en) | 2004-11-16 | 2004-12-15 | Gw Pharma Ltd | New use for cannabinoid |
KR20070089151A (ko) * | 2004-11-16 | 2007-08-30 | 지더블유 파마 리미티드 | 카나비노이드의 새로운 용도 |
GB2471523A (en) | 2009-07-03 | 2011-01-05 | Gw Pharma Ltd | Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy |
GB2487183B (en) * | 2011-01-04 | 2018-10-03 | Otsuka Pharma Co Ltd | Use of the phytocannabinoid cannabidivarin (CBDV) in the treatment of epilepsy |
TWI583374B (zh) | 2010-03-30 | 2017-05-21 | Gw伐瑪有限公司 | 使用植物大麻素次大麻二酚(cbdv)來治療癲癇之用途 |
GB2514054A (en) * | 2011-09-29 | 2014-11-12 | Gw Pharma Ltd | A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD) |
CA3013907C (en) * | 2013-10-29 | 2020-09-08 | Biotech Institute, Llc | Production and use of specialty cannabis with bd/bt genotype and a limonene-dominant terpene profile |
GB2530001B (en) | 2014-06-17 | 2019-01-16 | Gw Pharma Ltd | Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy |
GB2527599A (en) | 2014-06-27 | 2015-12-30 | Gw Pharma Ltd | Use of 7-OH-Cannabidiol (7-OH-CBD) and/or 7-OH-Cannabidivarin (7-OH-CBDV) in the treatment of epilepsy |
CA2961410C (en) | 2014-09-16 | 2023-07-11 | India Globalization Capital, Inc. | Cannabinoid composition and method for treating pain |
GB2531282A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabinoids in the treatment of epilepsy |
GB2531278A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabidiol in the treatment of intractable epilepsy |
GB2531281A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabidiol in the treatment of intractable epilepsy |
US10751300B2 (en) | 2015-01-25 | 2020-08-25 | India Globalization Capital, Inc. | Composition and method for treating seizure disorders |
US10406186B2 (en) | 2015-01-31 | 2019-09-10 | Constance Therapeutics, Inc. | Cannabis oil extracts and compositions |
US10238745B2 (en) | 2015-01-31 | 2019-03-26 | Constance Therapeutics, Inc. | Cannabinoid composition and products including α-tocopherol |
MX2017010872A (es) | 2015-02-27 | 2018-05-07 | Ebbu Llc | Composiciones que comprenden combinaciones de cannabinoides purificados, con al menos uno de flavonoides, terpenos o minerales. |
AU2016255707A1 (en) * | 2015-04-28 | 2017-11-30 | The Regents Of The University Of California | Uses of cannabidiol for treatment of infantile spasms |
GB2539472A (en) | 2015-06-17 | 2016-12-21 | Gw Res Ltd | Use of cannabinoids in the treatment of epilepsy |
GB2541191A (en) * | 2015-08-10 | 2017-02-15 | Gw Pharma Ltd | Use of cannabinoids in the treatment of epilepsy |
WO2017027651A1 (en) | 2015-08-12 | 2017-02-16 | India Globalization Capital, Inc. | Method and composition for treating cachexia and eating disorders |
EP3380096A4 (en) | 2015-11-24 | 2019-10-23 | Constance Therapeutics, Inc. | CANNABIS OIL COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
GB2548873B (en) | 2016-03-31 | 2020-12-02 | Gw Res Ltd | Use of Cannabidiol in the Treatment of SturgeWeber Syndrome |
GB2549278B (en) * | 2016-04-11 | 2021-02-17 | Gw Res Ltd | Use of cannabidivarin in the treatment of autism spectrum disorder |
US10499584B2 (en) | 2016-05-27 | 2019-12-10 | New West Genetics | Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles |
US10053407B2 (en) | 2016-06-01 | 2018-08-21 | S&B Pharma, Inc. | Crystalline cannabidivarin |
US10399920B2 (en) | 2016-06-01 | 2019-09-03 | S&B Pharma, Inc. | Crystalline form of cannabidiol |
EP3471746A4 (en) | 2016-06-15 | 2020-02-26 | India Globalization Capital, Inc. | METHOD AND COMPOSITION FOR TREATING EPILEPTIC DISORDERS |
CN109475586A (zh) | 2016-06-29 | 2019-03-15 | 康纳塞斯创新公司 | 脱羧的大麻树脂、其用途和制备其的方法 |
GB2551986A (en) | 2016-07-01 | 2018-01-10 | Gw Res Ltd | Parenteral formulations |
GB2551987A (en) | 2016-07-01 | 2018-01-10 | Gw Res Ltd | Oral cannabinoid formulations |
AU2017307643B2 (en) | 2016-08-03 | 2019-07-25 | Zelira Therapeutics Operations Pty Ltd | Cannabis Composition |
GB2553139A (en) | 2016-08-25 | 2018-02-28 | Gw Res Ltd | Use of cannabinoids in the treatment of multiple myeloma |
CA3034004C (en) | 2016-08-29 | 2021-08-03 | Canopy Growth Corporation | Water soluble compositions comprising purified cannabinoids |
GB2557921A (en) | 2016-12-16 | 2018-07-04 | Gw Res Ltd | Use of cannabinoids in the treatment of angelman syndrome |
CN108236608B (zh) * | 2016-12-27 | 2020-05-08 | 汉义生物科技(北京)有限公司 | 大麻二酚与氨己烯酸的药物组合物及其用途 |
CN108245510B (zh) * | 2016-12-29 | 2020-11-20 | 汉义生物科技(北京)有限公司 | 大麻二酚与乙丙酰脲类抗癫痫药物的组合物及其用途 |
CN108245517B (zh) * | 2016-12-29 | 2020-05-08 | 汉义生物科技(北京)有限公司 | 大麻二酚与拉莫三嗪的药物组合物及其用途 |
CN108245499B (zh) * | 2016-12-29 | 2020-11-20 | 汉义生物科技(北京)有限公司 | 大麻二酚与双链脂肪酸类抗癫痫药物的组合物及其用途 |
GB2559774B (en) | 2017-02-17 | 2021-09-29 | Gw Res Ltd | Oral cannabinoid formulations |
EP3589129A4 (en) * | 2017-03-01 | 2020-11-25 | Canopy Growth Corporation | USEFUL COMPOSITIONS SELECTED WITH PURIFIED CANNABINOIDS AND / OR PURIFIED TERPENS |
CN109106699A (zh) * | 2017-06-23 | 2019-01-01 | 汉义生物科技(北京)有限公司 | 一种用于治疗癫痫的药物组合物、其制备方法及用途 |
CN109498606A (zh) | 2017-09-15 | 2019-03-22 | 汉义生物科技(北京)有限公司 | 一种含有大麻二酚和/或次大麻二酚的组合物及其在治疗痛经中的应用 |
EP3720275A4 (en) * | 2017-12-08 | 2021-10-27 | Biotech Institute, LLC | PROPYL CANNABINOID HEMP PLANTS, METHOD OF MANUFACTURING AND METHOD OF USING THEREOF |
GB2569961B (en) | 2018-01-03 | 2021-12-22 | Gw Res Ltd | Pharmaceutical |
GB201806953D0 (en) | 2018-04-27 | 2018-06-13 | Gw Res Ltd | Cannabidiol Preparations |
WO2020123383A1 (en) * | 2018-12-10 | 2020-06-18 | Natural Extraction Systems, LLC | Compositions with novel cannabinoid and terpene profiles |
CN113874344A (zh) * | 2019-03-08 | 2021-12-31 | 加利福尼亚大学董事会 | 8,9-二氢大麻二酚化合物的用途 |
GB201916977D0 (en) * | 2019-11-21 | 2020-01-08 | Gw Res Ltd | Cannibidol-type cannabinoid compound |
CA3163788A1 (en) | 2019-12-06 | 2021-06-10 | JLABS Beauty LLC | Topical compositions containing rose oil and cannabidiol and methods of making and using the same |
GB202002754D0 (en) | 2020-02-27 | 2020-04-15 | Gw Res Ltd | Methods of treating tuberous sclerosis complex with cannabidiol and everolimus |
KR102371269B1 (ko) | 2020-03-11 | 2022-03-07 | 연세대학교 산학협력단 | VEGFR-3 발현 조절을 통한 mTOR 관련 질환의 예방 또는 치료 방법 |
AU2021276680A1 (en) | 2020-05-22 | 2023-01-19 | Ilera Derm LLC | Compositions for treating acne and dermatological conditions |
CA3187303A1 (en) | 2020-07-28 | 2022-02-03 | Impello Biosciences, Inc. | Methods and compositions for altering secondary metabolites in plants |
US11160757B1 (en) | 2020-10-12 | 2021-11-02 | GW Research Limited | pH dependent release coated microparticle cannabinoid formulations |
WO2022103639A1 (en) * | 2020-11-16 | 2022-05-19 | Orcosa Inc. | Methods of treating autoimmune or inflammatory conditions with cannabidiol or its derivatives/analogs |
US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
WO2022122904A1 (en) | 2020-12-09 | 2022-06-16 | Chanelle Mccoy Cbd Limited | A delayed-release capsule of cannabidiol |
GB2606334A (en) | 2021-02-12 | 2022-11-09 | Gw Res Ltd | Use of cannabidivarin in the treatment of seizures associated with canine epilepsy |
CN115583933B (zh) * | 2022-10-31 | 2024-02-06 | 暨明医药科技(苏州)有限公司 | 一种高纯度四氢大麻素同系物的制备方法 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403126B1 (en) | 1999-05-26 | 2002-06-11 | Websar Innovations Inc. | Cannabinoid extraction method |
US6949582B1 (en) | 1999-05-27 | 2005-09-27 | Wallace Walter H | Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment |
WO2002064109A2 (en) | 2001-02-14 | 2002-08-22 | Gw Pharma Limited | Mucoadhesive pharmaceutical formulations |
GB0103638D0 (en) * | 2001-02-14 | 2001-03-28 | Gw Pharmaceuticals Ltd | Pharmaceutical formulations |
GB0202385D0 (en) | 2002-02-01 | 2002-03-20 | Gw Pharma Ltd | Compositions for the treatment of nausea,vomiting,emesis,motion sicknes or like conditions |
ITPD20020138A1 (it) * | 2002-05-24 | 2003-11-24 | Matteo Bevilacqua | Composizione di sostanze a base terpenica, metodo di preparazione e metodo di dispersione in ambiente della medesima. |
DE10226494A1 (de) | 2002-06-14 | 2004-01-08 | Lts Lohmann Therapie-Systeme Ag | Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen |
EP1542657B8 (en) * | 2002-08-14 | 2012-03-14 | GW Pharma Limited | Cannabinoid liquid formulations for mucosal amdinistration |
GB2392093B (en) * | 2002-08-14 | 2006-03-08 | Gw Pharma Ltd | Pharmaceutical formulations |
DK1536810T3 (da) | 2002-08-14 | 2012-11-19 | Gw Pharma Ltd | Ekstrahering af farmaceutisk aktive cannabinoider fra plantematerialer |
KR20070089151A (ko) | 2004-11-16 | 2007-08-30 | 지더블유 파마 리미티드 | 카나비노이드의 새로운 용도 |
GB0425248D0 (en) | 2004-11-16 | 2004-12-15 | Gw Pharma Ltd | New use for cannabinoid |
TWI366460B (en) | 2005-06-16 | 2012-06-21 | Euro Celtique Sa | Cannabinoid active pharmaceutical ingredient for improved dosage forms |
GB2434312B (en) | 2006-01-18 | 2011-06-29 | Gw Pharma Ltd | Cannabinoid-containing plant extracts as neuroprotective agents |
WO2007142957A2 (en) | 2006-05-30 | 2007-12-13 | Air Systems | Gear drive damper |
GB2438682A (en) * | 2006-06-01 | 2007-12-05 | Gw Pharma Ltd | New use for cannabinoids |
US20080188461A1 (en) | 2007-02-01 | 2008-08-07 | Regents Of The University Of Michigan | Compositions and methods for detecting, preventing and treating seizures and seizure related disorders |
GB2448535A (en) * | 2007-04-19 | 2008-10-22 | Gw Pharma Ltd | New use for cannabinoid-containing plant extracts |
GB2449691A (en) | 2007-05-31 | 2008-12-03 | Gw Pharma Ltd | A reference plant lacking medicinal active compound expression |
GB2450753B (en) | 2007-07-06 | 2012-07-18 | Gw Pharma Ltd | New Pharmaceutical formulation |
GB2456183A (en) | 2008-01-04 | 2009-07-08 | Gw Pharma Ltd | Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament |
GB2459637B (en) | 2008-01-21 | 2012-06-06 | Gw Pharma Ltd | New use for cannabinoids |
ES2727648T3 (es) | 2008-03-26 | 2019-10-17 | Stichting Sanammad | Composiciones de goma de mascar que comprenden cannabinoides |
GB2478074B (en) | 2008-06-04 | 2012-12-26 | Gw Pharma Ltd | Anti-tumoural effects of cannabinoid combinations |
GB2478072B (en) | 2008-06-04 | 2012-12-26 | Gw Pharma Ltd | Anti-tumoural effects of cannabinoid combinations |
GB2471523A (en) | 2009-07-03 | 2011-01-05 | Gw Pharma Ltd | Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy |
GB2478595B (en) | 2010-03-12 | 2018-04-04 | Gw Pharma Ltd | Phytocannabinoids in the treatment of glioma |
TWI583374B (zh) | 2010-03-30 | 2017-05-21 | Gw伐瑪有限公司 | 使用植物大麻素次大麻二酚(cbdv)來治療癲癇之用途 |
GB2479153B (en) | 2010-03-30 | 2014-03-19 | Gw Pharma Ltd | The phytocannabinoid cannabidivarin (CBDV) for use in the treatment of epilepsy |
US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
GB2487712B (en) | 2011-01-04 | 2015-10-28 | Otsuka Pharma Co Ltd | Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy |
GB201111261D0 (en) | 2011-07-01 | 2011-08-17 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuro-degenerative diseases or disorders |
WO2013032351A1 (en) | 2011-08-26 | 2013-03-07 | BIAL - PORTELA & Cª, S.A. | Treatments involving eslicarbazepine acetate or eslicarbazepine |
GB2514054A (en) | 2011-09-29 | 2014-11-12 | Gw Pharma Ltd | A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD) |
GB2496687A (en) | 2011-11-21 | 2013-05-22 | Gw Pharma Ltd | Tetrahydrocannabivarin (THCV) in the protection of pancreatic islet cells |
US20150181924A1 (en) | 2013-10-31 | 2015-07-02 | Michael R. Llamas | Cannabidiol liquid composition for smoking |
WO2015142501A1 (en) | 2014-03-21 | 2015-09-24 | Bodybio Inc. | Methods and compositions for treating symptoms of diseases related to imbalance of essential fatty acids |
IL302782A (en) | 2014-05-29 | 2023-07-01 | Radius Pharmaceuticals Inc | Stable cannabinoid formulations |
GB2530001B (en) | 2014-06-17 | 2019-01-16 | Gw Pharma Ltd | Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy |
GB2531282A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabinoids in the treatment of epilepsy |
GB2531281A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabidiol in the treatment of intractable epilepsy |
GB2531278A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabidiol in the treatment of intractable epilepsy |
GB2539472A (en) | 2015-06-17 | 2016-12-21 | Gw Res Ltd | Use of cannabinoids in the treatment of epilepsy |
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2011
- 2011-03-15 TW TW100108735A patent/TWI583374B/zh active
- 2011-03-28 AR ARP110101014 patent/AR080730A1/es unknown
- 2011-03-30 AU AU2011234225A patent/AU2011234225B2/en active Active
- 2011-03-30 BR BR112012024480A patent/BR112012024480A8/pt not_active Application Discontinuation
- 2011-03-30 MY MYPI2012004222A patent/MY162129A/en unknown
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- 2011-03-30 MX MX2012011033A patent/MX2012011033A/es active IP Right Grant
- 2011-03-30 KR KR1020127028091A patent/KR101849703B1/ko active IP Right Grant
- 2011-03-30 CN CN201180026947.4A patent/CN103025325B/zh active Active
- 2011-03-30 EP EP20194696.9A patent/EP3763361A1/en active Pending
- 2011-03-30 WO PCT/GB2011/050649 patent/WO2011121351A1/en active Application Filing
- 2011-03-30 US US13/075,873 patent/US9125859B2/en active Active
- 2011-03-30 EA EA201290975A patent/EA036044B1/ru unknown
- 2011-03-30 EP EP11712658A patent/EP2552430A1/en not_active Withdrawn
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- 2011-03-30 JP JP2013501945A patent/JP5918748B2/ja active Active
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2012
- 2012-09-24 IL IL222132A patent/IL222132B/en active IP Right Grant
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2015
- 2015-04-14 US US14/685,753 patent/US10799467B2/en active Active
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2016
- 2016-10-11 AU AU2016244223A patent/AU2016244223A1/en not_active Abandoned
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2018
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2020
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