KR101837488B1 - 광학적으로 순수한 벤질-4-클로로페닐-c-글루코사이드 유도체 - Google Patents
광학적으로 순수한 벤질-4-클로로페닐-c-글루코사이드 유도체 Download PDFInfo
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- KR101837488B1 KR101837488B1 KR1020140037632A KR20140037632A KR101837488B1 KR 101837488 B1 KR101837488 B1 KR 101837488B1 KR 1020140037632 A KR1020140037632 A KR 1020140037632A KR 20140037632 A KR20140037632 A KR 20140037632A KR 101837488 B1 KR101837488 B1 KR 101837488B1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
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| CN201410004395.2A CN104761522B (zh) | 2014-01-03 | 2014-01-03 | 光学纯的苄基‑4‑氯苯基的c‑糖苷衍生物 |
| CN201410004395.2 | 2014-01-03 |
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| KR20150081220A KR20150081220A (ko) | 2015-07-13 |
| KR101837488B1 true KR101837488B1 (ko) | 2018-03-12 |
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| KR (1) | KR101837488B1 (enrdf_load_stackoverflow) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105153137A (zh) * | 2015-09-17 | 2015-12-16 | 上海应用技术学院 | 一种艾格列净的制备方法 |
| RU2739024C2 (ru) * | 2016-01-04 | 2020-12-21 | Че Иль Фармасьютикал Ко., Лтд. | С-гликозидные производные, содержащие конденсированное фенильное кольцо, или их фармацевтически приемлемые соли, способ получения таковых и фармацевтическая композиция, содержащая таковые |
| CN109476624B (zh) * | 2016-05-28 | 2021-07-09 | 吉林惠升生物制药有限公司 | 钠-葡萄糖协同转运蛋白2抑制剂的晶型 |
| CN108285439B (zh) * | 2017-01-09 | 2023-05-02 | 江苏天士力帝益药业有限公司 | 一种碳糖苷类钠葡萄糖转运蛋白体2抑制剂 |
| WO2019185026A1 (zh) * | 2018-03-30 | 2019-10-03 | 南京明德新药研发有限公司 | 作为SGLTs抑制剂的葡糖苷类衍生物及其应用 |
| CN110551088B (zh) * | 2018-06-01 | 2022-10-21 | 北京惠之衡生物科技有限公司 | 氘修饰的苄基-4-氯苯基的c-糖苷衍生物 |
| CN112047915B (zh) * | 2019-06-05 | 2023-02-17 | 北京惠之衡生物科技有限公司 | C-糖苷类衍生物新的制备工艺 |
| CN110683998A (zh) * | 2019-11-20 | 2020-01-14 | 杭州华东医药集团浙江华义制药有限公司 | 一种恩格列净中间体的制备方法 |
| CN113248464B (zh) * | 2021-05-31 | 2021-10-26 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的合成方法 |
| CN113045525B (zh) * | 2021-05-31 | 2021-09-17 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的制备方法及其制剂 |
| CN113336733B (zh) * | 2021-05-31 | 2022-02-18 | 北京惠之衡生物科技有限公司 | 一种sglt-2抑制剂的l-脯氨酸共结晶体的制备方法 |
| CN113248554A (zh) * | 2021-06-25 | 2021-08-13 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的杂质的合成方法 |
| CN113372315B (zh) * | 2021-08-12 | 2021-10-29 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的杂质的合成方法 |
| CN115073271A (zh) * | 2022-06-08 | 2022-09-20 | 苏州敬业医药化工有限公司 | 一种4’-(5-溴-2-氯苄基)苯酚的制备方法 |
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| WO2013000275A1 (zh) * | 2011-06-25 | 2013-01-03 | 山东轩竹医药科技有限公司 | C-糖苷衍生物 |
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| US6515117B2 (en) * | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
| EP1581543A4 (en) * | 2003-01-03 | 2008-03-19 | Bristol Myers Squibb Co | METHODS FOR PRODUCING SGLT2 GLYCOSIS C-ARYL INHIBITORS |
| KR20120007088A (ko) * | 2004-03-16 | 2012-01-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 글루코피라노실-치환된 벤졸 유도체, 당해 화합물을 함유하는 약제, 이의 용도 및 이의 제조 방법 |
| US7772191B2 (en) * | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
| PL2548871T3 (pl) * | 2010-03-18 | 2017-12-29 | Daiichi Sankyo Company, Limited | Pochodne imidazolu podstawionego cykloalkilem |
| WO2012025857A1 (en) * | 2010-08-23 | 2012-03-01 | Hetero Research Foundation | Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors |
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- 2014-01-03 CN CN201410004395.2A patent/CN104761522B/zh active Active
- 2014-01-03 CN CN201610635305.9A patent/CN106349201B/zh active Active
- 2014-03-06 JP JP2014043695A patent/JP6008892B2/ja active Active
- 2014-03-31 KR KR1020140037632A patent/KR101837488B1/ko active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013000275A1 (zh) * | 2011-06-25 | 2013-01-03 | 山东轩竹医药科技有限公司 | C-糖苷衍生物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015129106A (ja) | 2015-07-16 |
| KR20150081220A (ko) | 2015-07-13 |
| CN104761522A (zh) | 2015-07-08 |
| CN104761522B (zh) | 2017-02-15 |
| CN106349201B (zh) | 2018-09-18 |
| CN106349201A (zh) | 2017-01-25 |
| JP6008892B2 (ja) | 2016-10-19 |
| HK1207626A1 (zh) | 2016-02-05 |
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