HK1207626A1 - 光學純的苄基- -氯苯基的 -糖苷衍生物 - Google Patents
光學純的苄基- -氯苯基的 -糖苷衍生物Info
- Publication number
- HK1207626A1 HK1207626A1 HK15108213.7A HK15108213A HK1207626A1 HK 1207626 A1 HK1207626 A1 HK 1207626A1 HK 15108213 A HK15108213 A HK 15108213A HK 1207626 A1 HK1207626 A1 HK 1207626A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- chlorophenyl
- optically pure
- glucoside derivative
- pure benzyl
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/06—Heterocyclic radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410004395.2A CN104761522B (zh) | 2014-01-03 | 2014-01-03 | 光学纯的苄基‑4‑氯苯基的c‑糖苷衍生物 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1207626A1 true HK1207626A1 (zh) | 2016-02-05 |
Family
ID=53643666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15108213.7A HK1207626A1 (zh) | 2014-01-03 | 2015-08-25 | 光學純的苄基- -氯苯基的 -糖苷衍生物 |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP6008892B2 (zh) |
KR (1) | KR101837488B1 (zh) |
CN (2) | CN106349201B (zh) |
HK (1) | HK1207626A1 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105153137A (zh) * | 2015-09-17 | 2015-12-16 | 上海应用技术学院 | 一种艾格列净的制备方法 |
CA3010323C (en) * | 2016-01-04 | 2021-08-10 | Je Il Pharmaceutical Co., Ltd. | C-glycoside derivatives having fused phenyl ring or pharmaceutically acceptable salts thereof, method for preparing the same and pharmaceutical composition comprising the same |
EP3466940B1 (en) * | 2016-05-28 | 2021-11-17 | Ji Lin Hui Sheng Bio-Pharmaceutical Co., Ltd. | Crystal form of sodium-glucose cotransporter 2 inhibitor |
CN108285439B (zh) * | 2017-01-09 | 2023-05-02 | 江苏天士力帝益药业有限公司 | 一种碳糖苷类钠葡萄糖转运蛋白体2抑制剂 |
WO2019185026A1 (zh) * | 2018-03-30 | 2019-10-03 | 南京明德新药研发有限公司 | 作为SGLTs抑制剂的葡糖苷类衍生物及其应用 |
CN110551088B (zh) * | 2018-06-01 | 2022-10-21 | 北京惠之衡生物科技有限公司 | 氘修饰的苄基-4-氯苯基的c-糖苷衍生物 |
CN112047915B (zh) * | 2019-06-05 | 2023-02-17 | 北京惠之衡生物科技有限公司 | C-糖苷类衍生物新的制备工艺 |
CN110683998A (zh) * | 2019-11-20 | 2020-01-14 | 杭州华东医药集团浙江华义制药有限公司 | 一种恩格列净中间体的制备方法 |
CN113248464B (zh) * | 2021-05-31 | 2021-10-26 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的合成方法 |
CN113336733B (zh) * | 2021-05-31 | 2022-02-18 | 北京惠之衡生物科技有限公司 | 一种sglt-2抑制剂的l-脯氨酸共结晶体的制备方法 |
CN113045525B (zh) * | 2021-05-31 | 2021-09-17 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的制备方法及其制剂 |
CN113248554A (zh) * | 2021-06-25 | 2021-08-13 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的杂质的合成方法 |
CN113372315B (zh) * | 2021-08-12 | 2021-10-29 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的杂质的合成方法 |
CN115073271A (zh) * | 2022-06-08 | 2022-09-20 | 苏州敬业医药化工有限公司 | 一种4’-(5-溴-2-氯苄基)苯酚的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6515117B2 (en) * | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
CA2512389A1 (en) * | 2003-01-03 | 2004-07-29 | Bristol-Myers Squibb Company | Methods of producing c-aryl glucoside sglt2 inhibitors |
CA2557801C (en) * | 2004-03-16 | 2013-06-25 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof |
US7772191B2 (en) * | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
PL2548871T3 (pl) * | 2010-03-18 | 2017-12-29 | Daiichi Sankyo Company, Limited | Pochodne imidazolu podstawionego cykloalkilem |
WO2012025857A1 (en) * | 2010-08-23 | 2012-03-01 | Hetero Research Foundation | Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors |
US9562029B2 (en) * | 2011-06-25 | 2017-02-07 | Xuanzhu Pharma Co., Ltd. | C-glycoside derivatives |
-
2014
- 2014-01-03 CN CN201610635305.9A patent/CN106349201B/zh active Active
- 2014-01-03 CN CN201410004395.2A patent/CN104761522B/zh active Active
- 2014-03-06 JP JP2014043695A patent/JP6008892B2/ja active Active
- 2014-03-31 KR KR1020140037632A patent/KR101837488B1/ko active IP Right Grant
-
2015
- 2015-08-25 HK HK15108213.7A patent/HK1207626A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR101837488B1 (ko) | 2018-03-12 |
KR20150081220A (ko) | 2015-07-13 |
JP6008892B2 (ja) | 2016-10-19 |
CN104761522B (zh) | 2017-02-15 |
CN104761522A (zh) | 2015-07-08 |
CN106349201A (zh) | 2017-01-25 |
JP2015129106A (ja) | 2015-07-16 |
CN106349201B (zh) | 2018-09-18 |
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