KR101764822B1 - Cosmetic composition for whitening skin color - Google Patents
Cosmetic composition for whitening skin color Download PDFInfo
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- KR101764822B1 KR101764822B1 KR1020150153350A KR20150153350A KR101764822B1 KR 101764822 B1 KR101764822 B1 KR 101764822B1 KR 1020150153350 A KR1020150153350 A KR 1020150153350A KR 20150153350 A KR20150153350 A KR 20150153350A KR 101764822 B1 KR101764822 B1 KR 101764822B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention relates to a cosmetic composition, and more particularly, to a cosmetic composition having an enhanced whitening effect by containing an extract of Echinosophora koreana and an extract of Echinosophora koreensis as selected from shiitake mushroom and germinated barley.
Description
The present invention relates to a cosmetic composition, and more particularly, to a cosmetic composition having an enhanced whitening effect by containing an extract of Echinosophora koreana and an extract of Echinosophora koreensis as selected from shiitake mushroom and germinated barley.
Cosmetics are not only the traditional functions of cleansing and beautifying the human body by attracting and changing the appearance, but also due to external factors such as pollutants, stress and ultraviolet rays, internal factors such as impaired immune cell function and cell activity It has a skin protection function that removes or suppresses the causes of skin aging such as free radicals, free radicals, proteins due to free radicals, peroxides, nucleic acids, and cell membrane lipid breakage. In addition, cosmetics having whitening, skin wrinkle improvement and inhibition, and ultraviolet shielding function to meet consumers' desire for high-performance cosmetics are continuously being developed. In particular, whitening and anti-inflammatory products are of great interest to consumers. Accordingly, various cosmetic compositions have been developed as shown in the following Patent Documents so as to have a whitening function or alleviate an inflammatory reaction to minimize skin damage.
<Patent Literature>
Patent Publication No. 10-2010-0028286 (published on Mar. 17, 2011) "Composition for skin whitening"
Patent Publication No. 10-1077824 (Announcement of Oct. 28, 2011) "Cosmetic composition for improving atopy containing sunlight extract and preparation method thereof"
However, the conventional cosmetic composition is not satisfactory in the whitening and inflammation-reducing effect, and there is a problem that the composition using ilite, which is a mica-type mineral belonging to the monoclinic system, is not guaranteed for stability using minerals and the like.
SUMMARY OF THE INVENTION The present invention has been made to solve the above problems,
It is an object of the present invention to provide a cosmetic composition having a whitening effect.
It is another object of the present invention to provide a cosmetic composition having an anti-inflammatory effect.
In order to achieve the above object, the present invention is implemented by the following embodiments.
According to one embodiment of the present invention, the cosmetic composition according to the present invention is characterized in that it contains an extract of any one selected from the group consisting of mushroom and germinated barley, and a ganoderma extract.
According to another embodiment of the present invention, in the cosmetic composition according to the present invention, the mushroom extract or the germinated barley extract is used in an amount of 10 to 30 parts by weight per 100 parts by weight of the extract.
According to another embodiment of the present invention, the cosmetic composition according to the present invention is characterized in that the extract is contained in an amount of 0.1 to 2% by weight based on the total weight of the cosmetic composition.
According to another embodiment of the present invention, the cosmetic composition according to the present invention may further comprise at least one selected from the group consisting of purified water, disodium edetate, trehalose, glycerin, butyleneglycol, carbomer, potassium hydroxide, essential oil, Dried extract, green tea extract, ginkgo leaf extract, petal extract, and natural preservative.
According to another embodiment of the present invention, in the cosmetic composition according to the present invention, the essential oil is composed of Bergham berries oil, lavender oil, milk oil and sentenced geranium flower oil, and the petal extract is selected from the group consisting of peach tree flower extract, Extract, a lotus flower extract, and a magnolia tree flower extract, wherein the natural preservative is characterized by comprising an extract of Acerola japonica and an extract of Asniera.
According to another embodiment of the present invention, the cosmetic composition according to the present invention is characterized by further comprising at least one extract selected from the group consisting of Cymbidium, Pakira, Oncidium and Tendem.
According to another embodiment of the present invention, the cosmetic composition according to the present invention is characterized by having a formulation of a mask pack.
According to the present invention, the following effects can be obtained by this embodiment.
The present invention provides an improved whitening and anti-inflammatory effect, including an extract of one selected from shiitake mushroom and germinated barley, and a herbal extract.
Hereinafter, the cosmetic composition according to the present invention will be described in detail. Unless defined otherwise, all terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs and, if conflict with the meaning of the terms used herein, It follows the definition used in the specification. Further, the detailed description of known functions and configurations that may unnecessarily obscure the subject matter of the present invention will be omitted. Throughout the specification, when an element is referred to as "including " an element, it is understood that the element may include other elements as well, without departing from the other elements unless specifically stated otherwise.
Meanwhile, the 'extract' referred to in the present invention is a concept including both general hot water extract and ethanol extract as a concept including all common extracts. Particularly, 'hot water extract' is extracted by hot water extraction method using distilled water or purified water Ethanol extract "refers to an extract obtained by using a polar solvent selected from lower alcohols having 1 to 4 carbon atoms or a mixed solvent thereof, preferably ethanol.
The cosmetic composition according to one embodiment of the present invention includes extracts of any one selected from shiitake mushroom and germinated barley, The shiitake mushroom extract or germinated barley extract is used in an amount of 10 to 30 parts by weight based on 100 parts by weight of the extract, and the extract is contained in an amount of 0.1 to 2% by weight based on the total weight of the cosmetic composition. The cosmetic composition according to the present invention contains the shiitake mushroom extract or the germinated barley extract in the uroguanthus extract as described above and has an improved skin whitening effect as shown in the following experiment.
The cosmetic composition may be selected from the group consisting of purified water, disodium edetate, trehalose, glycerin, butyleneglycol, carbohydrate, potassium hydroxide, essential oil, phage-60 hydrogenated castor oil, green tea extract, Petal extract, natural preservative, and the like. Wherein the petroleum-derived extract is composed of a peach tree flower extract, a plum extract, a lotus flower extract, and a magnolia tree flower extract, wherein the natural preservative is selected from the group consisting of persimmon Pine fruit extract and earthy extract.
The cosmetic composition may further include an extract for enhancing the anti-inflammatory effect (hereinafter, referred to as 'inflammatory extract'), wherein the anti-inflammatory extract is selected from the group consisting of cymbidium, pachira, oncididum, And Dendrobium phalaenopsis. The present invention also relates to a method for preparing the same. It is preferable that 10 to 30 parts by weight of the anti-inflammatory extract is used relative to 100 parts by weight of the extract. The cosmetic composition according to another embodiment of the present invention contains the shiitake mushroom extract or the germinated barley extract and the anti-inflammatory extract as described above, and has the anti-inflammatory effect as shown in the following experiment.
The cosmetic composition of the present invention may further comprise a composition selected from the group consisting of water-soluble vitamins, oiliness vitamins, polymer peptides, polymeric polysaccharides, sphingolipids and seaweed extracts.
As the water-soluble vitamin, any of vitamin B1, vitamin B2, vitamin B6, pyridoxine, pyridoxine hydrochloride, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C and vitamin H can be used, And salts thereof (thiamine hydrochloride, sodium ascorbate, etc.) or derivatives (sodium ascorbic acid-2-phosphate, magnesium ascorbic acid-2-phosphate etc.) can also be used as water-soluble vitamins . The water-soluble vitamin can be obtained by a conventional method such as a microorganism conversion method, a purification method from a culture of a microorganism, an enzymatic method, or a chemical synthesis method.
As the above-mentioned useful vitamins, any vitamins A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol) , And derivatives thereof (such as palmitic acid ascorbin, stearic acid ascorbic acid, dipalmitic acid ascorbic acid, dl-alpha tocopheryl acetate, dl-alpha tocopherol nicotinic acid vitamin E, DL-pantothenyl alcohol, D-pantothenyl alcohol, Ethyl ether, etc.) and the like are also included in the usable vitamins used in the present invention. The usable vitamin can be obtained by a conventional method such as a microorganism conversion method, a purification method from a culture of a microorganism, an enzyme or a chemical synthesis method.
The polymeric peptide may be any compound as long as it can be compounded in a cosmetic, and preferably collagen, hydrolyzed collagen, gelatin, elastin, hydrolyzed elastin, keratin and the like. The polymeric peptide can be obtained by a conventional method such as purification from a culture broth of a microorganism, an enzymatic method, or a chemical synthesis method, or purified from natural products such as ducks such as pigs and cows and silk fiber of silkworms .
The polymeric polysaccharide may be any compound as long as it can be compounded in cosmetics, and examples thereof include hydroxyethylcellulose, xanthan gum, sodium hyaluronate, chondroitin sulfate or a salt thereof (sodium salt, etc.). For example, chondroitin sulfate or a salt thereof can be usually purified from mammals or fish.
The sphingogly lipid may be any as long as it can be compounded in cosmetics, and preferable examples thereof include ceramides, phytosphingosine and sphingoglycolipids. The sphingogly lipids can be purified from ordinary mammals, fish, shellfish, yeast or plants by a conventional method or can be obtained by chemical synthesis.
The seaweed extract may be any of those which can be compounded in cosmetics, but preferably include algae extract, red tiger extract, green algae extract and the like, and furthermore, coloring guanine, arginic acid, sodium alginate , Potassium alginate, and the like are also included in the seaweed extract used in the present invention. The seaweed extract can be obtained from seaweed by a conventional method.
The cosmetic composition of the present invention may contain other ingredients usually added to the cosmetic composition. For example, it is possible to use various additives such as a preservative, a moisturizer, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, an ultraviolet absorber, an antiseptic, a bactericide, an antioxidant, a plant extract, a pH adjuster, Cold agents, antiperspirants, purified water, and the like.
Examples of the above-mentioned fat-soluble ingredients include ester-based fats, hydrocarbon-based fats, silicon-based fats, fluorine-based fats, animal fats and plant fats and the like. Examples of the ester-based oil include glyceryl tri-2-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate, octyl palmitate, isostearyl isostearate, But are not limited to, ethylbutyl, butylbutyl, ethylbutylbutyl, butylbutyl, isobutylbutyl, isobutylbutyl, isobutylisobutyl, isobutylisobutyl, isobutylisobutyl, Trimethylol propane, triisostearic acid trimethylol propane, tetra-2-ethylhexanoic acid pentaerythritol tri (2-ethylhexanoic acid) But are not limited to, tallow, caprylic estersyl, decyl laurate, hexyl laurate, decyl myristate, myristyl myristate, myristine sasyl, stearyl stearate, decyl oleate, Examples of the isocyanates include isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, Ethylhexanoate, stearyl 2-ethylhexanoate, hexyl isostearate, ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicaprate, di (capryl, capric acid) propylene glycol , Propylene glycol dicaprylylate, dicapric acid neopentyl glycol, dioctanoic acid neopentyl glycol, tricarboxylic acid glyceryl, triunsaturated acid glyceryl, triisopalmitic acid glyceryl, triisostearic acid glyceryl, neopentanoic acid octyl Dodecylsuccinic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, Polyglycerin isostearic acid ester, triisocetyl citrate, triisoalkyl citrate, triisooctyl citrate, lauryl lactate, myristyl lactate, cetyl lactate, octyldecyl lactate, octyldecyl lactate, octyldecyl isostearate, polyglycerin oleic acid ester, But are not limited to, triethyl citrate, acetyl triethyl citrate, acetyl tributyl citrate, trioctyl citrate, diisostearyl malate, 2-ethylhexyl hydroxystearate, di-2-ethylhexyl succinate, diisobutyl adipate, Propyl stearate, propyl stearate, propyl stearate, stearyl stearate, stearyl stearate, propyl stearate, stearyl stearate, Stearyl hydroxystearate, stearyl 12-stearoyl hydroxystearate, 12-stearoyl hydroxystearic acid, Allo one hydroxy stearic acid and the like esters such as cetearyl source. Examples of the hydrocarbonaceous oil include hydrocarbons such as squalene, liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, floating isoparaffin, polybutene, microcrystalline wax and vaseline. Examples of the silicone-based oil include polymethyl silicone, methylphenyl silicone, methyl cyclopolysiloxane, octamethyl polysiloxane, decamethyl polysiloxane, dodecamethyl cyclosiloxane, dimethyl siloxane methyl cetyloxysiloxane copolymer, dimethyl siloxane methyl stearoxysiloxane copolymer, Alkyl-modified silicone oil, and amino-modified silicone oil. Examples of the fluorine-based oil include perfluoropolyether and the like. Examples of the animal or plant oil include avocado oil, almond oil, olive oil, sesame oil, rice bran oil, new flower oil, soybean oil, corn oil, rape oil, apricot kernel oil, palm kernel oil, palm oil, castor oil, The present invention relates to a process for producing a starch-containing starch, which is selected from the group consisting of seed oil, cottonseed oil, palm oil, palm oil, cucumber nut oil, wheat germ oil, rice germ oil, Animal or vegetable fats such as oil, can-pick wax, carnauba wax, liquid lanolin, and hardened castor oil.
Examples of the moisturizing agent include water-soluble low-molecular moisturizing agents, oil-soluble molecular moisturizing agents, water-soluble polymers, and oil-soluble polymers. Examples of the water-soluble low molecular weight moisturizing agent include serine, glutamine, sorbitol, mannitol, sodium pyrrolidone-carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B Propylene glycol (polymerization degree n = 2 or more), polyglycerin B (polymerization degree n = 2 or more), lactic acid, lactic acid salt and the like. Examples of the lipid-soluble low-molecular moisturizing agent include cholesterol, cholesterol ester and the like. Examples of the water-soluble polymer include carboxyvinyl polymer, polyaspartic acid salt, tragacanth, xanthan gum, methylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, water-soluble chitin, chitosan, dextrin, . Examples of the oil-soluble polymer include polyvinylpyrrolidone / eicosene copolymer, polyvinylpyrrolidone / hexadecene copolymer, nitrocellulose, dextrin fatty acid ester, and polymer silicone.
Examples of the molient agent include long chain acyl glutamic acid cholesteryl ester, hydroxystearic acid cholesteryl, 12-hydroxystearic acid, stearic acid, rosin acid and lanolin fatty acid cholesteryl ester.
Examples of the surfactant include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants. Examples of the nonionic surfactant include self emulsifying monostearic acid glycerin, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene), sorbitan fatty acid ester, POE sorbit fatty acid ester POE glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hardened castor oil, POE castor oil, POEPOP (polyoxyethylene polyoxypropylene) copolymer, POEPOP alkyl ether, polyether modified silicone, lauric acid alkanolamide , Alkylamine oxides, hydrogenated soybean phospholipids, and the like. Examples of the anionic surfactant include fatty acid soap, alpha-acylsulfonate, alkylsulfonate, alkylallylsulfonate, alkylnaphthalenesulfonate, alkylsulfate, POE alkyl ether sulfate, alkylamide sulfate, alkyl phosphate, POE alkyl ginseng salt, alkyl Amide phosphate, alkyloyl taurine salt, N-acyl amino acid salt, POE alkyl ether carboxylate, alkylsulfosuccinate, sodium alkylsulfoacetate, acylated hydrolyzed collagen peptide salt, perfluoroalkyl phosphate ester and the like . Examples of the cationic surfactant include alkyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, stearyl trimethyl ammonium bromide, cetostearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium chloride, behenyl trimethyl ammonium bromide, Benzalkonium chloride, diethylaminoethylamide stearate, dimethylaminopropylamide stearate, quaternary ammonium salts of lanolin derivatives, and the like. Examples of the amphoteric surfactant include carboxybetaine, amidebetaine, sulfobetaine, hydroxysulfobetaine, amidosulfobetaine, phosphobetaine, aminocarboxylate, imidazoline derivative, amideamine, etc. , And the like.
Examples of the organic and inorganic pigments include silicic acid, anhydrous silicic acid, magnesium silicate, talc, sericite, mica, kaolin, spinach, clay, bentonite, titanium coated mica, bismuth oxychloride, zirconium oxide, magnesium oxide, Inorganic pigments such as aluminum, calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, chromium oxide, chromium oxide, chromium oxide, But are not limited to, polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenol resin, fluororesin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, Silk powder, cellulose, CI Pigment Yellow, CI Pigment Orange, and composite pigments of inorganic pigments and organic pigments thereof.
Examples of the organic powder include metal soaps such as calcium stearate; Metal salts of alkyl phosphates such as sodium zinc cetylate, zinc laurylate and calcium lauryl laurate; Acylamino acid polyvalent metal salts such as N-lauroyl-beta-alanine calcium, N-lauroyl-beta-alanine zinc and N-lauroylglycine calcium; Amidosulfonic acid multivalent metal salts such as N-lauroyl-taurine calcium and N-palmitoyl-taurine calcium; Such as N-epsilon-lauroyl-L-lysine, N-epsilon-palmitoylidene, N-alpha-paratyylnitine, N-alpha-lauroyl arginine, Acyl basic amino acids; N-acylpolypeptides such as N-lauroylglycylglycine; Alpha-amino fatty acids such as alpha-aminocaprylic acid, alpha-aminoaurauric acid, and the like; Polyethylene, polypropylene, nylon, polymethylmethacrylate, polystyrene, divinylbenzene-styrene copolymer, ethylene tetrafluoride, and the like.
Examples of the ultraviolet absorber include ultraviolet absorbers such as p-aminobenzoic acid, ethyl p-aminobenzoate, amyl paranobenzoate, octyl p-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, benzyl salicylate, benzyl salicylate, butylphenyl salicylate, homomenthyl salicylate, Benzyl, 2-ethoxyethyl methoxycinnamate, octyl methoxycinnamate, mono-2-ethylhexane glyceryl dipyrromethoxycinnamate, isopropyl methoxycinnamate, diisopropyl-diisopropyl cinnamate ester mixture, Dihydroxymethoxybenzophenone sulfonic acid, dihydroxybenzophenone sulfonic acid, dihydroxybenzophenone sulfonic acid and its salt, dihydroxymethoxybenzophenone, sodium dihydroxymethoxybenzophenone disulfonate, dihydroxybenzo Phenanone, tetrahydroxybenzophenone, 4-tert-butyl-4'-methoxydibenzoylmethane, 2,4,6-trianylino-p- (carbo-2'-ethylhexyl- 1,3,5-triazine, 2- (2- And the like can be de-hydroxy-5-methylphenyl) benzotriazole.
Examples of the bactericide include antibiotics such as hinokitiol, trichloroacid, trichlorohydroxydiphenyl ether, crohexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, No. 301, mononitro and eicoll sodium, undecylenic acid, and the like.
Examples of the antioxidant include butylhydroxyanisole, gallic acid propyl, and eicosorbic acid.
Examples of the pH adjuster include citric acid, sodium citrate, malic acid, sodium malate, fumaric acid, sodium fumarate, succinic acid, sodium succinate, sodium hydroxide, sodium monohydrogenphosphate and the like.
Examples of the alcohol include higher alcohols such as cetyl alcohol.
In addition, any of the above components may be blended within the range not impairing the object and effect of the present invention, but is preferably 0.01 to 5% by weight based on the total weight, More preferably 0.01 to 3% by weight.
The cosmetic composition of the present invention may take the form of a solution, an emulsion, a viscous mixture or the like.
The ingredients contained in the cosmetic composition of the present invention may contain, as an active ingredient, the ingredients conventionally used in cosmetic compositions in addition to the above-mentioned compounds, for example, conventional additives such as stabilizers, solubilizers, vitamins, And a carrier.
The cosmetic composition of the present invention can be prepared in any formulations conventionally produced in the art, and examples thereof include emulsions, creams, foundations, lotions, essences, and hair cosmetic compositions. Specifically, the cosmetic composition of the present invention can be used as a skin lotion, a skin softener, a moisturizing lotion, a nutritional lotion, a massage cream, a nutrition cream, a hand cream, a moisturizing cream, an essence, a pack, a soap, a lotion, a milk lotion, A cleansing foam, a body cleanser, an astringent, a spray, and preferably a formulation of a mask pack. When the formulation of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component . When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, / Propane or dimethyl ether. In the case of the solution or emulsion of the present invention, a solvent, a solvent or an emulsifier is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters. When the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used. When the formulation of the present invention is an interfacial active agent-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, linolenic derivatives or ethoxylated glycerol fatty acid esters.
Hereinafter, the present invention will be described in more detail with reference to Examples. However, these are only for the purpose of illustrating the present invention in more detail, but the scope of the present invention is not limited thereto.
Example 1 Identification of whitening effect
(1) Preparation of sample
1) 100 g of each of dried, ground shark, shiitake mushroom and germinated barley was immersed in 400 ml of 80% ethanol for 48 hours, and the extract was concentrated under reduced pressure to obtain a herbal extract, a shiitake mushroom extract and a germinated barley extract.
2) Sample 1 was obtained by mixing the koi extract and mushroom extract at a weight ratio of 5: 1.
3) Sample 2 was obtained by mixing the gingko extract and the germinated barley extract in a weight ratio of 5: 1.
4) Samples 3 to 5 were obtained, each consisting of a sulphate extract, a shiitake mushroom extract and a germinated barley extract.
(2) Confirmation of intracellular inhibition of melanin formation
1) B16F1 melanoma cells used for screening whitening materials were grown in Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 10% fetal bovine serum (Gibco), 1% penicillin streptomycin and 1% antibiotic-antimycotic. The cells were transferred to 24-well plates and 8-well chamber slides (500,000 cells per well), treated with Samples 1 to 5 (each having a concentration of 100 μg / ml), and cultured for two days to recover the cells . The recovered cells were reacted with 1 N NaOH containing 10% dimethyl sulfoxide at 90 ° C for 2 hours to dissolve sufficiently in melanin. Then, the absorbance was measured using an ELISA reader, and the melanin production rate (%) was calculated Are shown in Table 1 below. The rate of melanin production (%) can be obtained from the absorbance of the treatment / the absorbance of the untreated solution × 100.
2) Table 1 below shows that the samples 1 and 2, which were prepared by mixing mushroom extract or germinated barley extract with the mushroom extract, respectively, showed a higher melanin production rate than the samples 3 to 5 comprising the mushroom extract, shiitake mushroom extract and germinated barley extract It is found that the cosmetic composition of the present invention improves the whitening effect.
<Example 2> Evaluation of anti-inflammatory effect
(1) Preparation of sample
1) 100 g of each dried and crushed Cymbidium leaf, Pakira leaf, Oncidium leaf and Tangerine leaf were immersed in 400 ml of 80% ethanol for 48 hours and the extract was concentrated under reduced pressure to obtain Cymbidium extract, Pakira extract, Oncidium extract and Tengareth extract .
2) Sample 1 was obtained by mixing the koi extract, shiitake mushroom extract and cymbidium extract in a weight ratio of 5: 1: 1.
3) Samples 2 to 4 were obtained by mixing Pakira extract, Oncidium extract and Tengareth extract, respectively, in place of Cymbidium extract in sample 1.
(2) Perform NO assay
1) An NO assay was conducted to investigate the effect of nitric oxide production, one of the active oxygen species, which is an inflammatory factor that causes atopy and acne.
2) RAW 264.7 cells were grown in DMEM medium supplemented with 10% FBS and 100 units / ml penicillin-streptomycin. RAW 264.7 cells were adjusted to 1.5 × 10 5 cells / mL using DMEM medium supplemented with 10% FBS and inoculated on a 24-well plate. The medium containing the sample and LPS (1 μg / mL) Respectively. The amount of NO produced was measured in the form of NO 2 - present in cell culture medium using Griess reagent. 100 μL of the cell culture supernatant and 100 μL of the Griess reagent were mixed and reacted for 10 minutes. The absorbance was measured by an ELISA reader and the NO production rate was calculated. The NO production rate was expressed as%, and 1 μg / mL of LPS was used. Unit is μM). Standard concentration curves were obtained by serial dilution of sodium nitrite (NaNO 2 ) (1-100 μM).
3) As shown in Table 2, in comparison with the control group, LPS alone treatment group, samples 1 to 4 were able to confirm NO production inhibitory effect in a concentration-dependent manner at concentrations of 300 μM or less. From the above experimental results, it can be seen that the cosmetic composition of the present invention does not inhibit the production of NO, an inflammatory factor that causes atopy and acne, and has an anti-inflammatory effect.
While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, Should be interpreted as belonging to the scope.
Claims (7)
Wherein the cosmetic composition comprises germinated barley extract and ginseng extract, wherein the germinated barley extract is used in an amount of 10 to 30 parts by weight based on 100 parts by weight of ginseng extract, has an effect of inhibiting melanin formation,
Wherein the cosmetic composition further comprises a pakira extract, and has an effect of inhibiting nitric oxide formation.
And 0.1 to 2% by weight based on the total weight of the cosmetic composition.
60 Hydrogenated Castor Oil, Green Tea Extract, Ginkgo Biloba Extract, Ginkgo Biloba Extract, Petal Extract, Natural Extracts, Natural Extracts, Natural Extracts, Wherein the cosmetic composition further comprises a preservative.
The essential oil is composed of bergamot fruit oil, lavender oil, milk oil and sentenced geranium flower oil,
The petal extract is composed of peach tree flower extract, plum extract, lotus flower extract and magnolia tree flower extract,
Wherein the natural preservative is composed of an extract of Acerola japonica fruit and an extract of Earthia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150153350A KR101764822B1 (en) | 2015-11-02 | 2015-11-02 | Cosmetic composition for whitening skin color |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR102124556B1 (en) * | 2020-01-31 | 2020-06-18 | 박장호 | Cosmetics for skin whitening including green barely extract and manufacturing method for the same |
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| KR102108116B1 (en) * | 2017-12-21 | 2020-06-03 | 탑월드(주) | A cosmetic composition comprising a natural component and an oil component |
| CN109464355A (en) * | 2018-12-28 | 2019-03-15 | 安徽中医药高等专科学校 | A kind of free modular facemask powder and preparation method thereof |
| CN110897992A (en) * | 2020-01-02 | 2020-03-24 | 广东立爽生物科技有限公司 | Halitosis removing toothpaste and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2002205933A (en) * | 2001-01-05 | 2002-07-23 | Ichimaru Pharcos Co Ltd | Cosmetic composition containing extract of orchidaceous plant |
| JP2011173851A (en) * | 2010-02-25 | 2011-09-08 | Kazki International:Kk | Patch for beautification |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2002205933A (en) * | 2001-01-05 | 2002-07-23 | Ichimaru Pharcos Co Ltd | Cosmetic composition containing extract of orchidaceous plant |
| JP2011173851A (en) * | 2010-02-25 | 2011-09-08 | Kazki International:Kk | Patch for beautification |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102124556B1 (en) * | 2020-01-31 | 2020-06-18 | 박장호 | Cosmetics for skin whitening including green barely extract and manufacturing method for the same |
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