KR101758583B1 - 통증을 치료 또는 완화하기 위한 설파메이트 유도체 화합물 - Google Patents

통증을 치료 또는 완화하기 위한 설파메이트 유도체 화합물 Download PDF

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Publication number
KR101758583B1
KR101758583B1 KR1020167013586A KR20167013586A KR101758583B1 KR 101758583 B1 KR101758583 B1 KR 101758583B1 KR 1020167013586 A KR1020167013586 A KR 1020167013586A KR 20167013586 A KR20167013586 A KR 20167013586A KR 101758583 B1 KR101758583 B1 KR 101758583B1
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South Korea
Prior art keywords
benzo
dioxin
chloro
sulfamate
dimethyl
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KR1020167013586A
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English (en)
Korean (ko)
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KR20160065984A (ko
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최용문
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(주)바이오팜솔루션즈
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00—Racemisation; Complete or partial inversion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR1020167013586A 2013-12-12 2014-12-12 통증을 치료 또는 완화하기 위한 설파메이트 유도체 화합물 Expired - Fee Related KR101758583B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361915042P 2013-12-12 2013-12-12
US61/915,042 2013-12-12
PCT/KR2014/012260 WO2015088272A1 (en) 2013-12-12 2014-12-12 Sulfamate derivative compounds for use in treating or alleviating pain

Publications (2)

Publication Number Publication Date
KR20160065984A KR20160065984A (ko) 2016-06-09
KR101758583B1 true KR101758583B1 (ko) 2017-07-14

Family

ID=53371494

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167013586A Expired - Fee Related KR101758583B1 (ko) 2013-12-12 2014-12-12 통증을 치료 또는 완화하기 위한 설파메이트 유도체 화합물

Country Status (7)

Country Link
US (1) US10081615B2 (https=)
EP (1) EP3079687B1 (https=)
JP (1) JP6311025B2 (https=)
KR (1) KR101758583B1 (https=)
CN (1) CN105979942B (https=)
ES (1) ES2663804T3 (https=)
WO (1) WO2015088272A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015088273A1 (en) * 2013-12-12 2015-06-18 Bio-Pharm Solutions, Co., Ltd. Sulfamate derivative compounds for use in treating or alleviating pain
WO2017150903A1 (en) 2016-02-29 2017-09-08 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds, processes for preparing them and their uses
CN114350340B (zh) * 2022-01-13 2023-01-17 陕西科技大学 一种压裂用增渗剂及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100063138A1 (en) 2008-07-22 2010-03-11 Mccomsey David F Novel substituted sulfamide derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582916A (en) 1983-09-26 1986-04-15 Mcneilab, Inc. Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol
US4591601A (en) * 1985-04-12 1986-05-27 Mcneilab, Inc. Anticonvulsant dioxolane methane sulfamates
EP0272223B1 (en) * 1987-02-05 1991-05-29 FARMACEUTICI CABER S.p.A. 4-oxo-1,3-benzodioxane derivative
US4792569A (en) 1987-08-27 1988-12-20 Mcneilab, Inc. Anticonvulsant phenethyl sulfamates
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
TW200823196A (en) * 2006-11-01 2008-06-01 Astrazeneca Ab New use
EP2271638B1 (en) * 2008-04-29 2011-08-31 NSAB, Filial af NeuroSearch Sweden AB, Sverige Modulators of dopamine neurotransmission
CA2817290A1 (en) * 2010-11-11 2012-05-18 Josef Penninger Compounds and methods for treating pain
WO2013187727A1 (en) 2012-06-15 2013-12-19 Bio-Pharm Solutions Co., Ltd. Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100063138A1 (en) 2008-07-22 2010-03-11 Mccomsey David F Novel substituted sulfamide derivatives

Also Published As

Publication number Publication date
EP3079687B1 (en) 2018-02-28
KR20160065984A (ko) 2016-06-09
US20160311792A1 (en) 2016-10-27
CN105979942B (zh) 2018-12-07
JP2017509582A (ja) 2017-04-06
EP3079687A4 (en) 2017-04-26
CN105979942A (zh) 2016-09-28
JP6311025B2 (ja) 2018-04-11
WO2015088272A9 (en) 2015-10-01
ES2663804T3 (es) 2018-04-17
EP3079687A1 (en) 2016-10-19
US10081615B2 (en) 2018-09-25
WO2015088272A1 (en) 2015-06-18

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