KR101748453B1 - 폐렴구균(Streptococcus Pneumoniae)에 대항하는 백신과 조성물 - Google Patents
폐렴구균(Streptococcus Pneumoniae)에 대항하는 백신과 조성물 Download PDFInfo
- Publication number
- KR101748453B1 KR101748453B1 KR1020127001971A KR20127001971A KR101748453B1 KR 101748453 B1 KR101748453 B1 KR 101748453B1 KR 1020127001971 A KR1020127001971 A KR 1020127001971A KR 20127001971 A KR20127001971 A KR 20127001971A KR 101748453 B1 KR101748453 B1 KR 101748453B1
- Authority
- KR
- South Korea
- Prior art keywords
- lys
- leu
- seq
- ala
- asp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22154109P | 2009-06-29 | 2009-06-29 | |
| US61/221,541 | 2009-06-29 | ||
| US24059809P | 2009-09-08 | 2009-09-08 | |
| US24061609P | 2009-09-08 | 2009-09-08 | |
| US61/240,598 | 2009-09-08 | ||
| US61/240,616 | 2009-09-08 | ||
| US31626710P | 2010-03-22 | 2010-03-22 | |
| US61/316,267 | 2010-03-22 | ||
| PCT/US2010/040406 WO2011008548A1 (en) | 2009-06-29 | 2010-06-29 | Vaccines and compositions against streptococcus pneumoniae |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120093141A KR20120093141A (ko) | 2012-08-22 |
| KR101748453B1 true KR101748453B1 (ko) | 2017-06-16 |
Family
ID=43449681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127001971A Expired - Fee Related KR101748453B1 (ko) | 2009-06-29 | 2010-06-29 | 폐렴구균(Streptococcus Pneumoniae)에 대항하는 백신과 조성물 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10105412B2 (enExample) |
| EP (1) | EP2448592B1 (enExample) |
| JP (1) | JP5931724B2 (enExample) |
| KR (1) | KR101748453B1 (enExample) |
| CN (2) | CN102548572A (enExample) |
| AU (1) | AU2010273708B2 (enExample) |
| BR (1) | BRPI1011919A2 (enExample) |
| CA (1) | CA2803061A1 (enExample) |
| IL (1) | IL217166A0 (enExample) |
| IN (1) | IN2012DN00791A (enExample) |
| MX (1) | MX2012000158A (enExample) |
| NZ (1) | NZ597858A (enExample) |
| RU (1) | RU2580299C2 (enExample) |
| SG (2) | SG177402A1 (enExample) |
| WO (1) | WO2011008548A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102548572A (zh) | 2009-06-29 | 2012-07-04 | 健诺西生物科学公司 | 抗肺炎链球菌的疫苗和组合物 |
| EP2550289A4 (en) | 2010-03-12 | 2013-11-27 | Childrens Medical Center | NEW IMMUNOGENES AND METHODS FOR IDENTIFICATION AND SCREENING THEREOF |
| SI2656070T1 (sl) * | 2010-12-21 | 2016-05-31 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Ugotavljanje učinkovitosti živega rekombinantnega antimikobakterijskega cepljenja |
| MY163871A (en) | 2011-01-20 | 2017-10-31 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
| AR085698A1 (es) * | 2011-03-09 | 2013-10-23 | Glaxosmithkline Llc | Inhibidores de la peptido desformilasa |
| US10766932B2 (en) | 2011-05-11 | 2020-09-08 | The Children's Medical Center Corporation | Multiple antigen presenting immunogenic composition, and methods and uses thereof |
| EP2804627B1 (en) * | 2012-01-20 | 2019-08-14 | Genocea Biosciences Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| WO2014018904A1 (en) * | 2012-07-26 | 2014-01-30 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| JP6494527B2 (ja) | 2013-02-07 | 2019-04-03 | ザ チルドレンズ メディカル センター コーポレーション | 肺炎球菌のコロニー形成および/または疾患からの保護を提供するタンパク質抗原 |
| US20150079132A1 (en) * | 2013-09-17 | 2015-03-19 | Path | Evoking protection against streptotoccus pneumoniae incorporating b-cell and t-cell pneumococcal protein antigens and pneumococcal polysaccharides delivered concomitantly |
| EP3131579A4 (en) | 2014-04-18 | 2017-10-25 | The Children's Medical Center Corporation | Vaccine adjuvant compositions |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| WO2018134693A1 (en) * | 2017-01-20 | 2018-07-26 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| CA3061709A1 (en) | 2017-03-28 | 2018-10-04 | The Children's Medical Center Corporation | A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
| BR112019027387A8 (pt) | 2017-06-23 | 2022-12-06 | Univ Maryland | Composições imunogênicas |
| MX2020005584A (es) | 2017-12-04 | 2020-09-14 | Intervet Int Bv | Vacunacion con particulas de replicon y adyuvante oleoso. |
| JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
| TWI852943B (zh) | 2018-09-12 | 2024-08-21 | 美商兒童醫療中心公司 | 肺炎鏈球菌融合蛋白疫苗 |
| RU2728938C1 (ru) * | 2020-05-06 | 2020-08-03 | Федеральное государственное бюджетное учреждение науки "Научный центр биомедицинских технологий Федерального медико-биологического агентства" (ФГБУН НЦБМТ ФМБА России) | Применение даларгина для производства лекарственных средств профилактики пневмонии |
| EP4181951A1 (en) | 2020-07-16 | 2023-05-24 | Zalvac AB | Streptococcal vaccines |
| IL311239A (en) | 2021-09-09 | 2024-05-01 | Affinivax Inc | Multivalent pneumococcal vaccines |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005503119A (ja) * | 2001-03-27 | 2005-02-03 | カイロン ソチエタ ア レスポンサビリタ リミタータ | Streptococcuspneumoniaeタンパク質および核酸 |
| JP2007525157A (ja) * | 2003-04-15 | 2007-09-06 | インターツェル・アクチェンゲゼルシャフト | 肺炎連鎖球菌抗原 |
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| CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| US5371197A (en) * | 1991-09-24 | 1994-12-06 | Merck & Co., Inc. | Protein-dimeric polysaccharide conjugate vaccine |
| US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
| WO1997037026A1 (en) | 1996-04-02 | 1997-10-09 | Smithkline Beecham Corporation | Novel compounds |
| US6420135B1 (en) * | 1996-10-31 | 2002-07-16 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
| AU735444B2 (en) | 1997-05-06 | 2001-07-05 | Human Genome Sciences, Inc. | (Enterococcus faecalis) polynucleotides and polypeptides |
| WO1998058943A1 (en) | 1997-06-20 | 1998-12-30 | Human Genome Sciences, Inc. | Borrelia burgdorferi polynucleotides and sequences |
| US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US5882885A (en) * | 1997-07-17 | 1999-03-16 | Smithkline Beecham Corporation | Glycogen phosphorylase |
| US5994101A (en) * | 1997-07-18 | 1999-11-30 | Smithkline Beecham Corporation | DNA encoding gidA1 polypeptides |
| US6617156B1 (en) * | 1997-08-15 | 2003-09-09 | Lynn A. Doucette-Stamm | Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics |
| US6248558B1 (en) | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
| CN1318103A (zh) | 1998-07-27 | 2001-10-17 | 微生物技术有限公司 | 肺炎链球菌的核酸和蛋白质 |
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| WO2008119358A2 (en) | 2007-03-30 | 2008-10-09 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides for use in vaccine compositions |
| CA2687375C (en) | 2007-05-18 | 2017-08-29 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Primers and probes for the detection of streptococcus pneumoniae |
| BRPI0811908A2 (pt) | 2007-05-25 | 2014-11-18 | Novartis Ag | Antígenos de pilus de streptococcus pneumoniae |
| WO2008150885A1 (en) * | 2007-05-29 | 2008-12-11 | Board Of Regents, The University Of Texas System | Modulation of the th-17 cell mediated immune responses |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| EP2225265A2 (en) | 2007-09-14 | 2010-09-08 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
| US7833776B2 (en) * | 2007-12-12 | 2010-11-16 | National Health Research Institutes | Lipidating sequences and use thereof for producing lipidated proteins in E. coli |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
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| EP3413049B1 (en) | 2008-07-01 | 2020-10-28 | Genocea Biosciences Inc. | Antigen screening system |
| CA2745205A1 (en) | 2008-12-03 | 2010-06-10 | Protea Vaccine Technologies Ltd. | Glutamyl trna synthetase (gts) fragments |
| US8287880B2 (en) * | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| US8658176B2 (en) * | 2009-06-22 | 2014-02-25 | National Health Research Institutes | Lipidated tumor-associated antigens and immunotherapeutic compositions |
| WO2010150242A2 (en) | 2009-06-25 | 2010-12-29 | Protea Vaccine Technologies Ltd. | Immunogenic streptococcus pneumoniae peptides and peptide-multimers |
| CN102548572A (zh) | 2009-06-29 | 2012-07-04 | 健诺西生物科学公司 | 抗肺炎链球菌的疫苗和组合物 |
| WO2011064781A1 (en) | 2009-11-30 | 2011-06-03 | Ben-Gurion University Of The Negev Research And Development Authority | S. pneumoniae adhesins |
| WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
| JP5065434B2 (ja) * | 2010-04-06 | 2012-10-31 | 株式会社日立製作所 | 管理方法及び管理装置 |
| WO2011128892A2 (en) | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Modified forms of pneumococcal surface immunogenic protein b (psipb) |
| US20110283062A1 (en) * | 2010-05-14 | 2011-11-17 | Hitachi, Ltd. | Storage apparatus and data retaining method for storage apparatus |
| MY163871A (en) * | 2011-01-20 | 2017-10-31 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
-
2010
- 2010-06-29 CN CN2010800388746A patent/CN102548572A/zh active Pending
- 2010-06-29 SG SG2011096898A patent/SG177402A1/en unknown
- 2010-06-29 RU RU2011153032/15A patent/RU2580299C2/ru not_active IP Right Cessation
- 2010-06-29 BR BRPI1011919A patent/BRPI1011919A2/pt not_active IP Right Cessation
- 2010-06-29 AU AU2010273708A patent/AU2010273708B2/en not_active Ceased
- 2010-06-29 CN CN201710169055.9A patent/CN107126557A/zh active Pending
- 2010-06-29 CA CA2803061A patent/CA2803061A1/en not_active Abandoned
- 2010-06-29 EP EP10800303.9A patent/EP2448592B1/en active Active
- 2010-06-29 WO PCT/US2010/040406 patent/WO2011008548A1/en not_active Ceased
- 2010-06-29 MX MX2012000158A patent/MX2012000158A/es unknown
- 2010-06-29 SG SG10201403702SA patent/SG10201403702SA/en unknown
- 2010-06-29 KR KR1020127001971A patent/KR101748453B1/ko not_active Expired - Fee Related
- 2010-06-29 US US12/826,084 patent/US10105412B2/en active Active
- 2010-06-29 JP JP2012518575A patent/JP5931724B2/ja not_active Expired - Fee Related
- 2010-06-29 NZ NZ597858A patent/NZ597858A/en not_active IP Right Cessation
- 2010-06-29 IN IN791DEN2012 patent/IN2012DN00791A/en unknown
-
2011
- 2011-12-22 IL IL217166A patent/IL217166A0/en unknown
-
2018
- 2018-09-17 US US16/133,590 patent/US11207375B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005503119A (ja) * | 2001-03-27 | 2005-02-03 | カイロン ソチエタ ア レスポンサビリタ リミタータ | Streptococcuspneumoniaeタンパク質および核酸 |
| JP2007525157A (ja) * | 2003-04-15 | 2007-09-06 | インターツェル・アクチェンゲゼルシャフト | 肺炎連鎖球菌抗原 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190298795A1 (en) | 2019-10-03 |
| IL217166A0 (en) | 2012-02-29 |
| WO2011008548A1 (en) | 2011-01-20 |
| US10105412B2 (en) | 2018-10-23 |
| BRPI1011919A2 (pt) | 2017-09-26 |
| CA2803061A1 (en) | 2011-01-20 |
| CN102548572A (zh) | 2012-07-04 |
| RU2011153032A (ru) | 2013-08-10 |
| NZ597858A (en) | 2014-01-31 |
| MX2012000158A (es) | 2012-06-08 |
| US20110020386A1 (en) | 2011-01-27 |
| SG177402A1 (en) | 2012-02-28 |
| EP2448592A1 (en) | 2012-05-09 |
| AU2010273708A1 (en) | 2012-02-23 |
| IN2012DN00791A (enExample) | 2015-06-26 |
| US11207375B2 (en) | 2021-12-28 |
| JP2012532134A (ja) | 2012-12-13 |
| EP2448592A4 (en) | 2013-04-24 |
| EP2448592B1 (en) | 2020-06-17 |
| RU2580299C2 (ru) | 2016-04-10 |
| AU2010273708B2 (en) | 2015-10-01 |
| SG10201403702SA (en) | 2014-09-26 |
| AU2010273708A8 (en) | 2012-06-14 |
| WO2011008548A8 (en) | 2012-03-08 |
| KR20120093141A (ko) | 2012-08-22 |
| JP5931724B2 (ja) | 2016-06-08 |
| CN107126557A (zh) | 2017-09-05 |
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| KR101748453B1 (ko) | 폐렴구균(Streptococcus Pneumoniae)에 대항하는 백신과 조성물 | |
| US10188717B2 (en) | Vaccines and compositions against Streptococcus pneumoniae | |
| JP2017160238A (ja) | ストレプトコッカス・ニューモニエ(Streptococcus pneumoniae)に対する融合抗原ワクチンおよび組成物 | |
| HK1172254A (en) | Vaccines and compositions against streptococcus pneumoniae | |
| HK1192166A (en) | Vaccines and compositions against streptococcus pneumoniae |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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