KR101739953B1 - 항 에이치비씨의 정량적인 검출 방법 및 만성 비형 간염 환자의 질병 진행의 모니터링 및 억제 및 치료 효과의 예측에 있어서 그의 용도 - Google Patents
항 에이치비씨의 정량적인 검출 방법 및 만성 비형 간염 환자의 질병 진행의 모니터링 및 억제 및 치료 효과의 예측에 있어서 그의 용도 Download PDFInfo
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- KR101739953B1 KR101739953B1 KR1020147023123A KR20147023123A KR101739953B1 KR 101739953 B1 KR101739953 B1 KR 101739953B1 KR 1020147023123 A KR1020147023123 A KR 1020147023123A KR 20147023123 A KR20147023123 A KR 20147023123A KR 101739953 B1 KR101739953 B1 KR 101739953B1
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
- G01N33/5762—Hepatitis B core antigen
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/40—Fish
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/02—Hepadnaviridae, e.g. hepatitis B virus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210019389.5 | 2012-01-21 | ||
| CN201210019389.5A CN103217533B (zh) | 2012-01-21 | 2012-01-21 | Anti-HBc定量检测方法及其在监控慢性乙肝患者病情发展和预测治疗疗效中的用途 |
| PCT/CN2013/070573 WO2013107355A1 (zh) | 2012-01-21 | 2013-01-17 | Anti-hbc 定量检测方法及其在监控慢性乙肝患者病情发展和预测治疗疗效中的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140117575A KR20140117575A (ko) | 2014-10-07 |
| KR101739953B1 true KR101739953B1 (ko) | 2017-05-25 |
Family
ID=48798632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147023123A Active KR101739953B1 (ko) | 2012-01-21 | 2013-01-17 | 항 에이치비씨의 정량적인 검출 방법 및 만성 비형 간염 환자의 질병 진행의 모니터링 및 억제 및 치료 효과의 예측에 있어서 그의 용도 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9952217B2 (https=) |
| EP (1) | EP2805729B1 (https=) |
| JP (2) | JP6283319B2 (https=) |
| KR (1) | KR101739953B1 (https=) |
| CN (1) | CN103217533B (https=) |
| AU (2) | AU2013211346B2 (https=) |
| BR (1) | BR112014017877B1 (https=) |
| CA (1) | CA2861917C (https=) |
| ES (1) | ES2714274T3 (https=) |
| WO (1) | WO2013107355A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104338132A (zh) * | 2013-07-26 | 2015-02-11 | 复旦大学 | 一种病毒免疫治疗药物复合物及其用途 |
| CN106153923B (zh) * | 2016-06-21 | 2017-12-05 | 北京大学第一医院 | 预测谷丙转氨酶小于二倍正常上限的慢性乙型病毒性肝炎患者肝脏炎症程度的系统 |
| CN107044977A (zh) * | 2016-06-30 | 2017-08-15 | 深圳市亚辉龙生物科技股份有限公司 | 一种酪氨酸磷酸酶抗体化学发光免疫检测试剂盒及其制备方法 |
| CN109991411B (zh) * | 2017-12-29 | 2023-01-20 | 上海索昕生物科技有限公司 | 一种检测待测样本中目标抗体的免疫测定方法及其应用 |
| CN109900896A (zh) * | 2019-03-12 | 2019-06-18 | 江苏伯纳德生物科技发展有限公司 | 一种酶联免疫法检测试剂盒及其制备方法 |
| WO2022252745A1 (zh) * | 2021-06-02 | 2022-12-08 | 重庆医科大学 | 一种免疫分子病毒颗粒检测试剂盒 |
| CN117538520B (zh) * | 2024-01-05 | 2024-04-02 | 山东康华生物医疗科技股份有限公司 | 一种HBc-IgM抗体检测试剂盒及其制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101545906A (zh) | 2008-03-25 | 2009-09-30 | 北京科美东雅生物技术有限公司 | 乙肝核心抗体磁微粒化学发光免疫分析测定试剂盒及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0382962A (ja) * | 1989-08-28 | 1991-04-08 | Tosoh Corp | B型肝炎ウィルスCore抗原に対する抗体の検出方法 |
| JP4292670B2 (ja) * | 2000-02-08 | 2009-07-08 | 東ソー株式会社 | 抗HBc抗体の免疫測定法 |
| ES2344737T3 (es) * | 2002-09-06 | 2010-09-06 | Advanced Life Science Institute, Inc. | Proteina del prenucleo de hbv capaz de formar particulas. |
| CN1908666B (zh) * | 2006-08-14 | 2010-05-12 | 武汉大学 | 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用 |
| CN101377496A (zh) * | 2008-04-16 | 2009-03-04 | 北京科美东雅生物技术有限公司 | 一种检测甲状腺过氧化物酶自身抗体的化学发光免疫分析测定试剂盒 |
| CN101726596A (zh) * | 2009-11-04 | 2010-06-09 | 无锡中德伯尔生物技术有限公司 | 检测乙肝五项的荧光微球免疫层析检测卡及其制备方法 |
-
2012
- 2012-01-21 CN CN201210019389.5A patent/CN103217533B/zh active Active
-
2013
- 2013-01-17 KR KR1020147023123A patent/KR101739953B1/ko active Active
- 2013-01-17 JP JP2014552496A patent/JP6283319B2/ja active Active
- 2013-01-17 ES ES13738450T patent/ES2714274T3/es active Active
- 2013-01-17 BR BR112014017877-1A patent/BR112014017877B1/pt active IP Right Grant
- 2013-01-17 US US14/373,611 patent/US9952217B2/en active Active
- 2013-01-17 EP EP13738450.9A patent/EP2805729B1/en active Active
- 2013-01-17 CA CA2861917A patent/CA2861917C/en active Active
- 2013-01-17 WO PCT/CN2013/070573 patent/WO2013107355A1/zh not_active Ceased
- 2013-01-17 AU AU2013211346A patent/AU2013211346B2/en active Active
-
2017
- 2017-09-28 JP JP2017188500A patent/JP2018036268A/ja not_active Abandoned
-
2018
- 2018-01-31 AU AU2018200744A patent/AU2018200744B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101545906A (zh) | 2008-03-25 | 2009-09-30 | 北京科美东雅生物技术有限公司 | 乙肝核心抗体磁微粒化学发光免疫分析测定试剂盒及其制备方法 |
Non-Patent Citations (3)
| Title |
|---|
| Hepatology, (1994), Vol. 19, No. 2, pp 303-311.* |
| J Hepatol., (1993), 19(3), pp 431-436. |
| Journal of Clinical Virology, (2006), 37, pp 206-212. |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018200744B2 (en) | 2019-08-08 |
| CA2861917C (en) | 2021-03-23 |
| CN103217533A (zh) | 2013-07-24 |
| KR20140117575A (ko) | 2014-10-07 |
| US9952217B2 (en) | 2018-04-24 |
| AU2013211346B2 (en) | 2017-11-30 |
| JP6283319B2 (ja) | 2018-02-21 |
| EP2805729B1 (en) | 2019-01-09 |
| EP2805729A4 (en) | 2015-11-11 |
| AU2013211346A1 (en) | 2014-08-28 |
| US20150118674A1 (en) | 2015-04-30 |
| BR112014017877A2 (https=) | 2017-06-20 |
| EP2805729A1 (en) | 2014-11-26 |
| BR112014017877B1 (pt) | 2022-01-25 |
| HK1198945A1 (en) | 2015-06-19 |
| CN103217533B (zh) | 2016-01-06 |
| JP2018036268A (ja) | 2018-03-08 |
| BR112014017877A8 (pt) | 2017-07-11 |
| ES2714274T3 (es) | 2019-05-28 |
| CA2861917A1 (en) | 2013-07-25 |
| AU2018200744A1 (en) | 2018-02-22 |
| WO2013107355A1 (zh) | 2013-07-25 |
| JP2015505371A (ja) | 2015-02-19 |
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