KR101738201B1 - 구토방지제로서의 아미설프라이드의 용도 - Google Patents

구토방지제로서의 아미설프라이드의 용도 Download PDF

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KR101738201B1
KR101738201B1 KR1020127024111A KR20127024111A KR101738201B1 KR 101738201 B1 KR101738201 B1 KR 101738201B1 KR 1020127024111 A KR1020127024111 A KR 1020127024111A KR 20127024111 A KR20127024111 A KR 20127024111A KR 101738201 B1 KR101738201 B1 KR 101738201B1
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vomiting
pharmaceutical composition
composition according
therapeutic pharmaceutical
amisulfide
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KR20130045241A (ko
Inventor
줄리안 클리브 길버트
로버트 윌리엄 그리스트우드
니콜라 쿠퍼
가브리엘 폭스
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아카시아 파마 리미티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020127024111A 2010-03-11 2011-03-10 구토방지제로서의 아미설프라이드의 용도 Active KR101738201B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1004020.2 2010-03-11
GBGB1004020.2A GB201004020D0 (en) 2010-03-11 2010-03-11 New therapeutic use
PCT/GB2011/050472 WO2011110854A2 (en) 2010-03-11 2011-03-10 The use of amisulpride as an anti-emetic

Publications (2)

Publication Number Publication Date
KR20130045241A KR20130045241A (ko) 2013-05-03
KR101738201B1 true KR101738201B1 (ko) 2017-05-19

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KR1020127024111A Active KR101738201B1 (ko) 2010-03-11 2011-03-10 구토방지제로서의 아미설프라이드의 용도

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US (12) US9084765B2 (enExample)
EP (3) EP2796171B1 (enExample)
JP (2) JP5886213B2 (enExample)
KR (1) KR101738201B1 (enExample)
CN (1) CN102892407B (enExample)
AU (1) AU2011225898B2 (enExample)
BR (1) BR112012022746B1 (enExample)
CA (1) CA2792392C (enExample)
CY (3) CY1115487T1 (enExample)
DK (3) DK2796171T3 (enExample)
EA (1) EA030335B1 (enExample)
ES (3) ES2665418T3 (enExample)
GB (1) GB201004020D0 (enExample)
HR (3) HRP20140744T1 (enExample)
HU (1) HUE037088T2 (enExample)
IL (1) IL221746A (enExample)
LT (1) LT2796171T (enExample)
MX (3) MX388787B (enExample)
NO (1) NO2796171T3 (enExample)
NZ (1) NZ602279A (enExample)
PL (3) PL2796171T3 (enExample)
PT (3) PT2796171T (enExample)
RS (3) RS53466B (enExample)
SI (3) SI2544657T1 (enExample)
SM (3) SMT201800188T1 (enExample)
WO (1) WO2011110854A2 (enExample)

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ES2665418T3 (es) 2018-04-25
NO2796171T3 (enExample) 2018-06-30
US20200093792A1 (en) 2020-03-26
US20130022689A1 (en) 2013-01-24
US12194022B2 (en) 2025-01-14
KR20130045241A (ko) 2013-05-03
EP2796171A1 (en) 2014-10-29
EA201290833A1 (ru) 2013-09-30
DK2796171T3 (en) 2018-05-07
JP2013522181A (ja) 2013-06-13
SI2796171T1 (en) 2018-05-31
EP2544657B1 (en) 2014-07-16
CY1120170T1 (el) 2018-12-12
WO2011110854A2 (en) 2011-09-15
US9119836B2 (en) 2015-09-01
US9084765B2 (en) 2015-07-21
PT2567690E (pt) 2014-09-03
US10525033B2 (en) 2020-01-07
PL2567690T3 (pl) 2014-11-28
RS53467B (sr) 2014-12-31
US20180353473A1 (en) 2018-12-13
SMT201400127B (it) 2015-05-05
CY1115487T1 (el) 2017-01-04
EP2567690A1 (en) 2013-03-13
PL2796171T3 (pl) 2018-07-31
WO2011110854A3 (en) 2011-11-10
EA030335B1 (ru) 2018-07-31
PT2796171T (pt) 2018-04-24
US20250186394A1 (en) 2025-06-12
US20180042896A1 (en) 2018-02-15
DK2567690T3 (da) 2014-08-11
US20150335616A1 (en) 2015-11-26
CN102892407A (zh) 2013-01-23
MX370629B (es) 2019-12-18
US10085970B2 (en) 2018-10-02
US9545426B2 (en) 2017-01-17
AU2011225898A1 (en) 2012-10-04
SI2567690T1 (sl) 2014-12-31
US20140147517A1 (en) 2014-05-29
US8686019B2 (en) 2014-04-01
HK1179152A1 (zh) 2013-09-27
SMT201800188T1 (it) 2018-07-17
EP2544657A2 (en) 2013-01-16
US20170087128A1 (en) 2017-03-30
HRP20140745T1 (hr) 2014-09-26
CY1115485T1 (el) 2017-01-04
AU2011225898B2 (en) 2014-07-03
US20220296570A1 (en) 2022-09-22
EP2567690B1 (en) 2014-07-16
CN102892407B (zh) 2016-03-23
MX2019015396A (es) 2020-02-07
JP6279526B2 (ja) 2018-02-14
IL221746A (en) 2017-03-30
GB201004020D0 (en) 2010-04-21
BR112012022746B1 (pt) 2021-09-28
HUE037088T2 (hu) 2018-08-28
ES2496092T3 (es) 2014-09-18
PT2544657E (pt) 2014-09-03
RS57032B1 (sr) 2018-05-31
EP2796171B1 (en) 2018-01-31
CA2792392C (en) 2018-06-19
DK2544657T3 (da) 2014-08-11
BR112012022746A2 (pt) 2016-07-05
PL2544657T3 (pl) 2014-10-31
US9889118B2 (en) 2018-02-13
JP5886213B2 (ja) 2016-03-16
JP2016028090A (ja) 2016-02-25
MX2012010411A (es) 2012-11-30
US20230144973A1 (en) 2023-05-11
SI2544657T1 (sl) 2014-12-31
ES2496099T3 (es) 2014-09-18
US20210228543A1 (en) 2021-07-29
US20130022688A1 (en) 2013-01-24
NZ602279A (en) 2014-08-29
HRP20140744T1 (hr) 2014-09-26
LT2796171T (lt) 2018-05-10
RS53466B (sr) 2014-12-31
MX388787B (es) 2025-03-20
HRP20180436T1 (hr) 2018-05-04
CA2792392A1 (en) 2011-09-15
SMT201400126B (it) 2015-05-05

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