KR101720808B1 - 세포를 체액으로부터 분리하기 위한 시스템 및 방법 - Google Patents

세포를 체액으로부터 분리하기 위한 시스템 및 방법 Download PDF

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Publication number
KR101720808B1
KR101720808B1 KR1020117012466A KR20117012466A KR101720808B1 KR 101720808 B1 KR101720808 B1 KR 101720808B1 KR 1020117012466 A KR1020117012466 A KR 1020117012466A KR 20117012466 A KR20117012466 A KR 20117012466A KR 101720808 B1 KR101720808 B1 KR 101720808B1
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biological materials
container
vessel
treating biological
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Expired - Fee Related
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KR20110090995A (ko
Inventor
피터 밀러
브라이언 디. 폴리조티
레지날드 디. 스미스
안업 수드
니콜 엘. 우드
리밍 유
홍이 조우
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제너럴 일렉트릭 캄파니
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Priority claimed from US12/325,672 external-priority patent/US8961787B2/en
Priority claimed from US12/333,926 external-priority patent/US20100151438A1/en
Application filed by 제너럴 일렉트릭 캄파니 filed Critical 제너럴 일렉트릭 캄파니
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Assigned to 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 reassignment 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 권리의 전부이전등록 Assignors: 제너럴 일렉트릭 캄파니
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/341—Regulation parameters by measuring the filtrate rate or volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/3406—Physical characteristics of the filtrate, e.g. urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424—Substitution fluid path
    • A61M1/3431—Substitution fluid path upstream of the filter
    • A61M1/3434—Substitution fluid path upstream of the filter with pre-dilution and post-dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424—Substitution fluid path
    • A61M1/3437—Substitution fluid path downstream of the filter, e.g. post-dilution with filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D36/00—Filter circuits or combinations of filters with other separating devices
    • B01D36/04—Combinations of filters with settling tanks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Clinical Laboratory Science (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020117012466A 2008-12-01 2009-11-24 세포를 체액으로부터 분리하기 위한 시스템 및 방법 Expired - Fee Related KR101720808B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/325,672 US8961787B2 (en) 2008-12-01 2008-12-01 Systems and methods for processing complex biological materials
US12/325,672 2008-12-01
US12/333,926 2008-12-12
US12/333,926 US20100151438A1 (en) 2008-12-12 2008-12-12 Methods and kits for enhancing sedimentation and recovery of cells in a sample
PCT/SE2009/051327 WO2010064973A1 (en) 2008-12-01 2009-11-24 System and method for separating cells from body fluids

Publications (2)

Publication Number Publication Date
KR20110090995A KR20110090995A (ko) 2011-08-10
KR101720808B1 true KR101720808B1 (ko) 2017-03-28

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Application Number Title Priority Date Filing Date
KR1020117012466A Expired - Fee Related KR101720808B1 (ko) 2008-12-01 2009-11-24 세포를 체액으로부터 분리하기 위한 시스템 및 방법

Country Status (6)

Country Link
EP (1) EP2352533B1 (enExample)
JP (1) JP5709758B2 (enExample)
KR (1) KR101720808B1 (enExample)
CN (1) CN102264410B (enExample)
CA (1) CA2745214C (enExample)
WO (1) WO2010064973A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150299657A1 (en) * 2014-04-16 2015-10-22 General Electric Company Gamma stabilized dextran solutions and methods of use
US20130131546A1 (en) * 2011-11-23 2013-05-23 Harvest Technologies Corporation System for collecting and processing bone marrow
GB201306810D0 (en) 2013-04-15 2013-05-29 Cells4Life Group Llp Methods of cell separation
GB2525202A (en) * 2014-04-15 2015-10-21 Cells4Life Group Llp Methods of cell separation
SG11201705529WA (en) * 2015-01-09 2017-08-30 Aviva Biosciences Corp Methods and devices for breaking cell aggregation and separating or enriching cells
US10859563B2 (en) * 2015-12-01 2020-12-08 General Electric Company Erythrocyte aggregation and leukocyte isolation
CN106267418B (zh) * 2016-07-01 2019-01-22 翁炳焕 母胎血型不合抗体吸附治疗仪
EP3470142A1 (de) 2017-10-11 2019-04-17 Orthogen AG Vorrichtung mit einer ersten kammer zur aufnahme eines körperfluids
KR20210092324A (ko) * 2018-12-13 2021-07-23 콜리고 테라퓨틱스, 인코포레이티드 세포 분리 장치 및 사용 방법
JP7580076B2 (ja) * 2019-01-24 2024-11-11 住友ゴム工業株式会社 細胞培養装置及び細胞培養方法
CN113748199B (zh) * 2019-03-26 2024-10-25 株式会社美加细胞 细胞悬浮液处理装置
JP7390677B2 (ja) * 2019-03-26 2023-12-04 キヤノン株式会社 細胞懸濁液処理装置
CN109893902A (zh) * 2019-04-11 2019-06-18 四川汇宇生物技术有限公司 一种明胶分离提纯系统
WO2023009782A1 (en) * 2021-07-30 2023-02-02 General Electric Company Techniques for isolation or analysis of bacterial pathogens from patient samples

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030134416A1 (en) 2001-10-11 2003-07-17 Douglas Yamanishi Methods, compositions, and automated systems for separating rare cells from fluid samples

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663058A (en) * 1983-10-11 1987-05-05 E. I. Du Pont De Nemours And Company Process for continuous separation of leukocyte/platelet-enriched fraction from whole blood
NL9320033A (nl) * 1992-06-10 1995-04-03 Pall Corp Systeem voor het behandelen van overgangsgebiedmateriaal.
AU4785493A (en) * 1992-07-31 1994-03-03 Basil E. Wainwright Apparatus and method for inactivation of human immunodeficiency virus
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
AU705225B2 (en) 1995-03-23 1999-05-20 Biopure Corporation Stable polymerized hemoglobin blood substitute
US6444471B1 (en) * 1999-10-18 2002-09-03 Research & Diagnostic Systems, Inc. Reticulocyte containing complete blood control
US9144583B2 (en) * 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
JP4567446B2 (ja) * 2002-06-19 2010-10-20 ノースウエスト バイオセラピューティクス，インコーポレイティド 白血球富化のための平行流濾過デバイスおよび方法
DE102004018347A1 (de) * 2004-04-06 2005-10-27 Manfred Dr. Schmolz Wundheilungsfördende Botenstoffmischung
JP4925159B2 (ja) * 2005-10-12 2012-04-25 日機装株式会社 血液浄化装置
WO2007049286A1 (en) * 2005-10-27 2007-05-03 Tata Memorial Centre A system for ex-vivo separation of apoptotic chromatin particles from blood or plasma
CN101801431B (zh) * 2007-06-22 2014-11-19 循环生物制品有限责任公司 流体浓缩器和自体浓缩体液及其使用方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030134416A1 (en) 2001-10-11 2003-07-17 Douglas Yamanishi Methods, compositions, and automated systems for separating rare cells from fluid samples

Also Published As

Publication number Publication date
JP2012510271A (ja) 2012-05-10
JP5709758B2 (ja) 2015-04-30
KR20110090995A (ko) 2011-08-10
CA2745214A1 (en) 2010-06-10
EP2352533A4 (en) 2013-08-07
CA2745214C (en) 2017-11-21
EP2352533A1 (en) 2011-08-10
CN102264410B (zh) 2016-08-03
WO2010064973A1 (en) 2010-06-10
CN102264410A (zh) 2011-11-30
EP2352533B1 (en) 2018-01-10

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