KR101716763B1 - Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition - Google Patents
Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition Download PDFInfo
- Publication number
- KR101716763B1 KR101716763B1 KR1020150066834A KR20150066834A KR101716763B1 KR 101716763 B1 KR101716763 B1 KR 101716763B1 KR 1020150066834 A KR1020150066834 A KR 1020150066834A KR 20150066834 A KR20150066834 A KR 20150066834A KR 101716763 B1 KR101716763 B1 KR 101716763B1
- Authority
- KR
- South Korea
- Prior art keywords
- ginseng
- weight
- cricket
- parts
- feeding
- Prior art date
Links
- 235000008434 ginseng Nutrition 0.000 title claims abstract description 108
- 241000238814 Orthoptera Species 0.000 title claims abstract description 90
- 229930182490 saponin Natural products 0.000 title claims abstract description 53
- 150000007949 saponins Chemical class 0.000 title claims abstract description 53
- 239000001397 quillaja saponaria molina bark Substances 0.000 title claims abstract description 45
- 150000004676 glycans Chemical class 0.000 title claims abstract description 42
- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 42
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 42
- 229930182494 ginsenoside Natural products 0.000 title claims abstract description 29
- 229940089161 ginsenoside Drugs 0.000 title claims abstract description 28
- 239000000284 extract Substances 0.000 title claims abstract description 24
- 235000013305 food Nutrition 0.000 title claims abstract description 12
- 239000000203 mixture Substances 0.000 title claims abstract description 11
- 238000009395 breeding Methods 0.000 title claims description 12
- 235000002789 Panax ginseng Nutrition 0.000 title description 2
- 240000004371 Panax ginseng Species 0.000 title 1
- 241000208340 Araliaceae Species 0.000 claims abstract description 107
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 107
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 107
- 239000000843 powder Substances 0.000 claims abstract description 28
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 27
- 239000011575 calcium Substances 0.000 claims abstract description 27
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 27
- 241000209094 Oryza Species 0.000 claims abstract description 23
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 23
- 235000009566 rice Nutrition 0.000 claims abstract description 23
- 238000000034 method Methods 0.000 claims abstract description 19
- 241001454694 Clupeiformes Species 0.000 claims abstract description 16
- 235000019513 anchovy Nutrition 0.000 claims abstract description 16
- 102000002322 Egg Proteins Human genes 0.000 claims abstract description 13
- 108010000912 Egg Proteins Proteins 0.000 claims abstract description 13
- 210000003278 egg shell Anatomy 0.000 claims abstract description 13
- 238000010298 pulverizing process Methods 0.000 claims abstract description 7
- 238000009835 boiling Methods 0.000 claims abstract description 5
- 238000001035 drying Methods 0.000 claims abstract description 5
- 238000002360 preparation method Methods 0.000 claims abstract description 4
- 235000017709 saponins Nutrition 0.000 claims description 48
- 230000012447 hatching Effects 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 230000001488 breeding effect Effects 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 5
- 238000004108 freeze drying Methods 0.000 claims description 3
- 241000196324 Embryophyta Species 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 238000003809 water extraction Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 abstract description 5
- 230000035764 nutrition Effects 0.000 abstract description 5
- 230000001737 promoting effect Effects 0.000 description 29
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 18
- 230000009471 action Effects 0.000 description 16
- 230000000694 effects Effects 0.000 description 16
- 230000002401 inhibitory effect Effects 0.000 description 14
- 230000003213 activating effect Effects 0.000 description 11
- 230000028327 secretion Effects 0.000 description 10
- 241000238631 Hexapoda Species 0.000 description 8
- 230000006819 RNA synthesis Effects 0.000 description 8
- 230000006870 function Effects 0.000 description 8
- 210000005036 nerve Anatomy 0.000 description 6
- 230000001965 increasing effect Effects 0.000 description 5
- 239000000275 Adrenocorticotropic Hormone Substances 0.000 description 4
- 102000004506 Blood Proteins Human genes 0.000 description 4
- 108010017384 Blood Proteins Proteins 0.000 description 4
- 101800000414 Corticotropin Proteins 0.000 description 4
- 102100027467 Pro-opiomelanocortin Human genes 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 description 4
- 229960000258 corticotropin Drugs 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 230000013011 mating Effects 0.000 description 4
- 229940012957 plasmin Drugs 0.000 description 4
- 238000001243 protein synthesis Methods 0.000 description 4
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 4
- 230000014616 translation Effects 0.000 description 4
- 208000035143 Bacterial infection Diseases 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 230000001093 anti-cancer Effects 0.000 description 3
- 230000003178 anti-diabetic effect Effects 0.000 description 3
- 208000022362 bacterial infectious disease Diseases 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000000502 dialysis Methods 0.000 description 3
- 150000002009 diols Chemical class 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000002540 macrophage Anatomy 0.000 description 3
- 230000015654 memory Effects 0.000 description 3
- 230000006820 DNA synthesis Effects 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 229920002670 Fructan Polymers 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 206010050661 Platelet aggregation inhibition Diseases 0.000 description 2
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 2
- 239000003470 adrenal cortex hormone Substances 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 230000002929 anti-fatigue Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 230000002180 anti-stress Effects 0.000 description 2
- 239000004019 antithrombin Substances 0.000 description 2
- 230000005880 cancer cell killing Effects 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 239000003246 corticosteroid Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000002964 excitative effect Effects 0.000 description 2
- 235000019197 fats Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 230000002443 hepatoprotective effect Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 230000000147 hypnotic effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 210000000822 natural killer cell Anatomy 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 229920001197 polyacetylene Polymers 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 241000712461 unidentified influenza virus Species 0.000 description 2
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- MYKOKMFESWKQRX-UHFFFAOYSA-N 10h-anthracen-9-one;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 MYKOKMFESWKQRX-UHFFFAOYSA-N 0.000 description 1
- RMZNXRYIFGTWPF-UHFFFAOYSA-N 2-nitrosoacetic acid Chemical compound OC(=O)CN=O RMZNXRYIFGTWPF-UHFFFAOYSA-N 0.000 description 1
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 description 1
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- AEMOLEFTQBMNLQ-YMDCURPLSA-N D-galactopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-YMDCURPLSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 102000013462 Interleukin-12 Human genes 0.000 description 1
- 108010065805 Interleukin-12 Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical class CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 239000012506 Sephacryl® Substances 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 230000024932 T cell mediated immunity Effects 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 description 1
- 230000001315 anti-hyperlipaemic effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003472 antidiabetic agent Substances 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000002798 bone marrow cell Anatomy 0.000 description 1
- 235000001465 calcium Nutrition 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 230000003013 cytotoxicity Effects 0.000 description 1
- 231100000135 cytotoxicity Toxicity 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 241001233061 earthworms Species 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 229940107131 ginseng root Drugs 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 230000013632 homeostatic process Effects 0.000 description 1
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000012155 injection solvent Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000009027 insemination Effects 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 229940117681 interleukin-12 Drugs 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000006993 memory improvement Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 229940012843 omega-3 fatty acid Drugs 0.000 description 1
- -1 omega-3 fatty acids Chemical class 0.000 description 1
- 239000006014 omega-3 oil Substances 0.000 description 1
- 210000004976 peripheral blood cell Anatomy 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000001603 reducing effect Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 150000004072 triols Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/90—Feeding-stuffs specially adapted for particular animals for insects, e.g. bees or silkworms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/204—Animal extracts
Abstract
The present invention relates to a method of raising a cricket containing ginsenoside-type saponin and a ginseng polysaccharide, and a food composition containing the cricket extract and the extract thereof raised by the method of raising the cricket. More particularly, And a cricket containing ginsenoside-type saponin and ginseng polysaccharide capable of producing crickets excellent in nutrition and function by containing ginsenoside-based saponin and ginseng polysaccharide in crickets by feeding ginseng in accordance with the step And a food composition containing the extract of the cricket raised by the feeding method.
The method for raising crickets containing ginsenoside-based saponin and ginseng polysaccharide according to the present invention comprises preparing a source of rice bran, ginseng and calcium, wherein the ginseng is prepared by pulverizing ginseng of 4-year-old root ginseng to 30 to 40 mesh, Wherein the anchovy powder is prepared by boiling broth and drying the remaining anchovy residue to 30 to 40 mesh, and the egg shell powder is pulverized into 20 to 30 mesh Preparing; Preparing a feed containing rice bran, ginseng and a calcium source prepared in the preparation step, feeding the feed to the cricket three times a day, and in the fifth instar period of the cricket, 3 to 5 parts by weight of the ginseng is added to 100 parts by weight of the rice bran , 5 to 7 parts by weight of a calcium source, and feeding the feed; A second feeding step of preparing and feeding a feed comprising 5 to 10 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran at the sixth instar of the cricket; A third feeding step of preparing and feeding a feed comprising 10 to 15 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran in the period 7 to 9 of the cricket; .
Description
The present invention relates to a method of raising a cricket containing ginsenoside-type saponin and a ginseng polysaccharide, and a food composition containing the cricket extract and the extract thereof raised by the method of raising the cricket. More particularly, And a cricket containing ginsenoside-type saponin and ginseng polysaccharide capable of producing crickets excellent in nutrition and function by containing ginsenoside-based saponin and ginseng polysaccharide in crickets by feeding ginseng in accordance with the step And a food composition containing the extract of the cricket raised by the feeding method.
Herbal medicine raw materials such as ginseng, Hwanggi, and myeonmundong have been widely used for the purpose of relieving diseases and healing in general, and ginseng has been used for many years as the most noble herbal medicine ingredient in the Far East. Ginseng is the broadest concept that includes both ginseng, white ginseng, red ginseng, wild ginseng, camphor, ginseng, raw ginseng, and taekguk ginseng. Through the history of long use, ginseng has been listed as one of the most important health functional food in Korea.
Ginseng contains 50-70% of carbohydrates, 10-15% of crude protein, 3-8% of crude saponin and 3-7% of ash, and the major physiologically active ingredients are saponin, phenolic component, polyacetylene component, Alkaloid components, polysaccharides and the like are known. Among them, ginseng saponin, which is called "ginsenoside", is named among the saponins of ginseng among the various saponins of plants. Ginseng saponin is a glycoside composed of glycone and aglycone. Up to now, about 30 species have been isolated and their structure is known.
The ginsenosides are classified into three classes of 37 kinds including diols, triols, and olefins according to their basic structures. Here, the diol system is sedated, and the triol system has an exciting function and an opposite function to each other, but plays a very important role in maintaining the homeostasis according to the state of the body. The diol system includes Rb1, Rb2, Rc, and Rd, and the triol system includes Re, Rf, Rg1, Rg2, and the like.
The R0 represents anti-inflammatory, detoxifying, antithrombin, platelet aggregation inhibiting, anti-hepatitis, and macrophage activation.
In addition, Rb1 may be used for the treatment of central nervous system depression, hypnotic action, analgesic action, mental stabilization action, antipyretic action, serum protein synthesis promoting action, neutral fat dissolving inhibiting action, synthesis promoting action (insulin similar action), cholesterol biosynthesis promoting action, RNA synthesis promoting action and hormone secretion promoting action, and Rb2 represents a central nerve inhibitory action, a DNA / RNA synthesis promoting action, a prasmin activating action, a corticosteroid stimulating hormone secretion promoting action, an anti-diabetic action, , RNA synthesis inhibitory action, serum protein synthesis promoting action, prasmin activating action, and adrenocorticotropic hormone secretion promoting action, and Rd exhibits action promoting adrenocortical hormone secretion.
In addition, Re shows central nerve inhibitory action, DNA / RNA promoting action, plasmin activating action, promoting adrenocorticotropic hormone secretion promoting action, Rf shows analgesic action related to neuronal cells, Rg1 is central nerve excitatory action, , Fatigue recovery, memory, learning function improving action, DNA · RNA synthesis promoting action, and prasmin activating action. Rg2 shows platelet aggregation inhibiting action and plasmin activating action.
Rh1 also exhibits anticancer activity, platelet aggregation inhibition and hepatoprotective actions, and Rh3 exhibits liver-detoxifying activity.
Recently, it has been found that various non-saponin fractions other than the saponin component have various pharmacological activities. Therefore, researches on pharmacological activity focusing on these active fractions have been variously developed.
Non-saponins include essential oils, phytosterols, polyacetylenes, polyphenols, flavonoids, polysaccharides, alkaloids, vitamins, minerals and enzymes. .
The polysaccharide is a pure polysaccharide composed of glucan (polysaccharide composed of glucose) and fructan (polysaccharide composed of fructan) and is a nano-polymer substance having a molecular weight of about 5,000 to 15,000. Promotes the regeneration and differentiation of peripheral blood cells as well as bone marrow cells, thereby promoting hematopoiesis and antimicrobial action and reducing side effects caused by radiation therapy. In addition, activation of macrophages promotes the production of interleukin-12, thereby activating the production of interferon by Th1-lymphocytes, thereby increasing the ability of natural killer cells (NK-Cell) and enhancing the cellular immune response (CTL) . In addition, it has been reported that it is effective for diseases such as diabetes by lowering blood sugar.
On the other hand, insects are mainly regarded as insect pests and have been focused on controlling them. However, studies on insect insects have not been studied yet. In recent years, some insects have been used to industrially use insect bioactive materials or to develop pharmaceuticals while newly recognizing the diversity and characteristics of insects.
Among them, crickets live around the islands and have habit of hiding in grassland or under the gardens of the garden, and the area of males is set. Most of them live on the ground, but they live on water, in the house, and in the house of ants. I put the ovipositor in the ground and spawn, and it dries in the ground in an egg state. It appears once a year from the middle of August to the end of October. It is generally omnivorous and rotten grass as a stock, but it also carnivorous, such as eating a small insect or the like, as well as a fountain. It also eats corpses such as insects and earthworms. In addition, the generation is short and it is evaluated as a useful biomass which is more industrialized in terms of time and economy than other biological resources.
Specifically, crickets are rich in unsaturated fatty acids including omega-3 fatty acids, and contain high levels of protein and chitin / chitosan. They are added to some animal feeds or gradually used as human high-protein foods. Development is necessary.
Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made keeping in mind the above problems occurring in the prior art, and an object of the present invention is to provide a ginseng saponin and a ginseng polysaccharide in crickets by feeding ginseng in accordance with the growth stage of crickets, The present invention relates to a method for raising crickets containing ginsenoside-type saponin and ginseng polysaccharide, which can produce crickets excellent in nutrition and function, and to provide a food composition containing the cricket extract and its extracts raised by the raising method .
In order to achieve the above object, the present invention provides a source of rice bran, ginseng and calcium, wherein the ginseng is prepared by pulverizing ginseng of 4-year-old root ginseng to 30 to 40 mesh, wherein the calcium source is anchovy powder or egg shell powder The anchovy powder is prepared by boiling the broth and drying the remaining anchovy residue to 30 to 40 mesh, and the egg shell powder is prepared by pulverizing the egg shell into 20 to 30 mesh; Preparing a feed containing rice bran, ginseng and a calcium source prepared in the preparation step, feeding the feed to the cricket three times a day, and in the fifth instar period of the cricket, 3 to 5 parts by weight of the ginseng is added to 100 parts by weight of the rice bran , 5 to 7 parts by weight of a calcium source, and feeding the feed; A second feeding step of preparing and feeding a feed comprising 5 to 10 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran at the sixth instar of the cricket; A third feeding step of preparing and feeding a feed comprising 10 to 15 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran in the period 7 to 9 of the cricket; .
The method of breeding crickets containing the ginsenoside-based saponin and the ginseng polysaccharide according to the present invention and the food composition containing the cricket extract and the extract thereof raised by the method of breeding according to the present invention, The effect of adding ginseng and the content of saponin in crickets can be maximized.
In addition, the crickets raised by the breeding method described above contain ginsenoside-based saponin and ginsenoside polysaccharide in the cricket as the ginseng is ingested. As a result, the ginsenoside-containing saponins are more effective than the crickets in enhancing immunity, It has the effect of enhancing the anti-stress, anti-fatigue, memory improvement, skin beauty and cancer cell kill ability by ginseng polysaccharide, influenza virus and bacterial infection inhibiting action, liver function improving action and the like.
In addition, the cricket containing the ginsenoside-based saponin and the ginseng polysaccharide of the present invention promotes growth of the cricket by feeding the nutrient-rich ginseng at the time when the ginseng is important, and particularly, The hatching rate is increased by 50 ~ 70%.
In addition, since crickets with excellent nutrition and function can be mass-produced, it can contribute to increase in income of the production farmers.
Hereinafter, preferred embodiments of the present invention will be described in detail. These examples are for further illustrating the present invention, and the scope of rights of the present invention is not limited to these examples.
The method for raising crickets containing ginsenoside-based saponin and ginseng polysaccharide according to the present invention comprises the steps of preparing a source of rice bran, ginseng, and calcium; Preparing a feed containing the rice bran, ginseng, and calcium source prepared in the preparation step, and feeding the feed to the cricket three times a day, wherein the amount of the ginseng is varied according to the growth stage of the cricket; A second feeding step; A third pay step; .
More specifically, the ginseng is prepared by pulverizing ginseng of 4-year-old root ginseng to 30 to 40 mesh. The reason why the ginseng is used as a 4-year-old root is that the 4-year-old ginseng has a higher saponin content than the 5-year-old or 6-year-old root, as shown in Table 1 below. As shown in Table 2, the saponin content of the bottom portion of the ginseng is higher than that of the other portions of the ginseng, so that the present invention can increase the saponin content of crickets by using 4 years old ginseng.
(Table 1) Saponin content by lotus root (%)
(Table 2) Saponin content per part (mg / g)
The calcium source is composed of at least one of anchovy powder and egg shell powder. The anchovy powder is prepared by boiling the broth and drying the remaining anchovy residue to 30 to 40 mesh. The egg shell powder comprises 20% To 30 mesh.
Next, the feed containing the rice bran, ginseng, and calcium source is prepared and fed to the cricket three times a day. In the fifth period of the cricket, 3 to 5 parts by weight of the ginseng, 5 to 7 parts by weight of a feed is prepared and fed.
The reason why the first salivation step is started at the fifth instar period is that since the effect of the ginseng is slightly expressed before the fifth instar, it is preferable that the insemination is performed from the fifth instar period when the significant effect is exhibited.
In addition, if the amount of the ginseng contained in the feed of the fifth age group is more than 5 parts by weight, the effect of increasing the weight of ginseng is not significantly increased, so that the raw material can be wasted. When the amount is less than 3 parts by weight, the content of saponin in the cricket decreases .
If the amount of the calcium source is more than 7 parts by weight, adverse effects due to excessive calcium intake may occur. If the amount is less than 5 parts by weight, the effect of calcium may be deteriorated.
Next, during the sixth instar of the cricket, a second feeding step of preparing and feeding a feed comprising 5 to 10 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran is performed.
Next, in the 7th to 9th orders of the cricket, a third feeding step in which a feed comprising 10 to 15 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source is prepared and fed to 100 parts by weight of the rice bran. At this time, the 7th to 9th orders are characterized by having the highest content of ginseng in the adult stage.
If the ginseng content exceeds the maximum value, the effect of weight gain may not be increased and the saponin content in the cricket may decrease when the ginseng content is below the minimum value, as in the first feeding step. There is an effect that the effect and the saponin content can be maximized by feeding the ginseng content suitable for each period.
As a result, the crickets raised by the above breeding method have an effect of containing ginsenoside-based saponin and ginseng polysaccharide in the cricket as the ginseng is ingested. Therefore, the cricket of the present invention is more effective than the cricket in general, because it has the ability to enhance immunity by ginsenoside saponins, anticancer, anti-diabetic, blood flow improvement, antistress, anti-fatigue, memory, skin cancer and cancer cell killings by ginseng polysaccharide, And bacterial infection-suppressing action, and liver function-improving action.
In addition, the cricket containing the ginsenoside-based saponin and the ginseng polysaccharide of the present invention promotes growth of the cricket by feeding the nutrient-rich ginseng at the time when the ginseng is important, and particularly, And the hatching rate is improved by 50 to 70%.
As a result, the breeding method can produce crickets with excellent nutrition and function, thereby contributing to an increase in income of the production farmers.
On the other hand, crickets raised by the breeding method were subjected to hot water extraction by adding 10 times as much weight of distilled water as the cricket weight, and the obtained hot water extract solution was concentrated at a ratio of 1/50 to 1/60, followed by lyophilization. And a concentration of 250 to 350 mg / kg to prepare cricket extract containing ginsenoside-based saponin and ginseng polysaccharide.
In addition, the food composition containing the extract may be prepared in various forms including powders, pills, and capsules, and may be easily ingested.
<
Example
1>
Ginsenoside system
Saponin and
Ginseng polysaccharide
Breeding crickets containing
First, rice ginseng, ginseng, and calcium sources were prepared. The ginseng was prepared by pulverizing 4-year-old ginseng root with 30 mesh. The calcium source was prepared by boiling broth, drying the remaining anchovy residue, Prepare an egg shell powder that has been pulverized into 30 mesh shells.
5 parts by weight of the ginseng, 5 parts by weight of the anchovy powder 3, and 3 parts by weight of the ginseng powder were added to 100 parts by weight of the rice bran at the fifth instar period of the cricket, And 3 parts by weight of the egg shell powder are prepared and fed to the first feeding step.
In the sixth period of the cricket, a second feeding step of preparing and feeding a feed comprising 100 parts by weight of the rice husk, 10 parts by weight of the ginseng, 3 parts by weight of the anchovy powder and 3 parts by weight of the egg shell powder is performed .
A third feeding step of preparing and feeding a feed comprising 15 parts by weight of the ginseng, 3 parts by weight of the anchovy powder and 3 parts by weight of the egg shell powder to 100 parts by weight of the rice bran is carried out at the 7th to 9th instar periods of the cricket do.
<
Test Example
1> Comparison of spawning and hatching rate
In order to compare the scattering and hatching rates of the crickets raised in Example 1, the crickets of Example 1 and Comparative Example 1 were placed at a temperature of 30 ° C, a humidity of 60% 10 hours of illumination, 14 hours of darkness.
As a result, in Example 1, male mating was very active after adultization, and it was confirmed that active mating was in progress through the number of male cries for mating, and many spawning occurred when a medium for mass scattering after mating was introduced, The number of hatching in the hatching medium having the width x height x 20 cm x 10 cm x 3 cm when the medium was transferred to the incubation chamber after the spawning was counted as shown in Table 3 below.
(Table 3) Number of hatching (horses)
As shown in Table 3, in the hatching medium of width x height x height 20 cm x 10 cm x 3 cm, the hatching number of each hatch was 32,472 in Example 1 and 20,648 in Comparative Example 1, Which was about 57% higher than that of the control group.
Thus, the method of raising crickets containing the ginsenoside-type saponin and the ginseng polysaccharide of the present invention has an effect of contributing to an increase in income of a production farm by enhancing the scattering and hatching rate by 50 to 70%.
<
Test Example
2>
Ginsenoside system
Saponin and
Ginseng polysaccharide
analysis
The crickets raised in Example 1 and the ginsenoside-containing saponins and ginseng polysaccharides of Comparative Example 1, which is a general cricket, were analyzed.
The analytical method of the ginsenoside-based saponin was performed by freezing the cricket in an HPLC method, lyophilizing it in a freeze dryer at a temperature of -30 to -38 ° C, pulverizing it to 30 to 40 mesh to prepare a cricket powder, After adding 10 times 70% methanol based on the weight of the powder, it was extracted three times by reflux in a constant temperature water bath at 80 캜 and dried under reduced pressure. Water was added thereto, diethyl ether was added to remove fat-soluble components, extracted three times with water-saturated n-butanol, and concentrated under reduced pressure. Methanol was used as the final injection solvent. Then, the presence or absence of ginsenoside-based saponin was analyzed using a reversed phase column (C18) and a UV detector (PerkinElmer Series 200 HPLC, 203 nm).
The analytical method of the ginseng polysaccharide was performed by extracting water-soluble extracts three times for 8 hours with 8 times the amount of the cricket powder, lyophilizing the extract, and dissolving the extract in methanol to separate the methanol solubles and the non-solubles. Methanol solubles were excluded because they showed cytotoxicity against mouse normal lymphocytes. The methanol non-soluble matter (yield: 10.1%) was dissolved again in distilled water, and three times the amount of ethanol was added thereto to separate the ethanol-soluble matter (yield: 4.1%) and the ethanol-non-soluble matter (yield: 6.4% Was dialyzed with distilled water using a cellulose dialysis membrane. The dialysis was performed for 1 week at 4 ° C by changing the distilled water every 12 hours. The inside of the dialysis membrane was collected by lyophilization (yield: 3.5%) and the lyophilized product was subjected to Sephacryl S200 column chromatography. The column (2.5x90 cm) was filled with the filler, and the flow rate was adjusted so that the eluate was discharged 1 ml per minute, and 100 eluates were collected in 10 ml increments. Glucose and galactose, which constitute the ginseng polysaccharide, were detected by an anthrone-sulfuric acid reaction, and galacturonic acid, which is an acidic sugar, was measured for uronic acid content Lt; / RTI >
(Table 4) Analysis results of ginsenoside-type saponin and ginseng polysaccharide
(o: detected, -: not detected)
As shown in Table 4, the crickets raised by the method of breeding crickets containing the ginsenoside-based saponin and the ginseng polysaccharide of the present invention contain many ginsenoside-based saponins and ginseng polysaccharides as compared with general crickets appear.
The ginsenoside-based saponin R0 contained in the cricket of the present invention exhibits anti-inflammatory action, detoxifying action, antithrombin action, platelet aggregation inhibitory action, anti-hepatitis action and macrophage activation action.
In addition, Rb1 may be used for the treatment of central nervous system depression, hypnotic action, analgesic action, mental stabilization action, antipyretic action, serum protein synthesis promoting action, neutral fat dissolving inhibiting action, synthesis promoting action (insulin similar action), cholesterol biosynthesis promoting action, RNA synthesis promoting action and hormone secretion promoting action, and Rb2 represents a central nerve inhibitory action, a DNA / RNA synthesis promoting action, a prasmin activating action, a corticosteroid stimulating hormone secretion promoting action, an anti-diabetic action, , RNA synthesis inhibitory action, serum protein synthesis promoting action, prasmin activating action, and adrenocorticotropic hormone secretion promoting action, and Rd exhibits action promoting adrenocortical hormone secretion.
In addition, Re shows central nerve inhibitory action, DNA / RNA promoting action, plasmin activating action, promoting adrenocorticotropic hormone secretion promoting action, Rf shows analgesic action related to neuronal cells, Rg1 is central nerve excitatory action, , Fatigue recovery, memory, learning function improving action, DNA · RNA synthesis promoting action, and prasmin activating action. Rg2 shows platelet aggregation inhibiting action and plasmin activating action.
Rh1 also exhibits anticancer activity, platelet aggregation inhibition and hepatoprotective actions, and Rh3 exhibits liver-detoxifying activity.
In addition, the ginseng polysaccharide contained in the cricket of the present invention is useful as an anti-inflammatory agent for preventing and treating diseases such as cancer cell killing ability, influenza virus and bacterial infection inhibiting action, liver function improving action, triglyceride inhibition, antihyperlipidemic effect, immune enhancement, .
Thus, the cricket of the present invention containing the ginsenoside-based saponin and the ginseng polysaccharide can exhibit various healthful effects as described above.
Claims (4)
Preparing a feed containing rice bran, ginseng and a calcium source prepared in the preparation step, feeding the feed to the cricket three times a day, and in the fifth instar period of the cricket, 3 to 5 parts by weight of the ginseng is added to 100 parts by weight of the rice bran , 5 to 7 parts by weight of a calcium source, and feeding the feed;
A second feeding step of preparing and feeding a feed comprising 5 to 10 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran at the sixth instar of the cricket;
A third feeding step of preparing and feeding a feed comprising 10 to 15 parts by weight of the ginseng and 5 to 7 parts by weight of a calcium source to 100 parts by weight of the rice bran in the period 7 to 9 of the cricket; A method for breeding crickets containing ginsenoside-based saponins and ginseng polysaccharides.
A cricket containing the ginsenoside-based saponin and ginseng polysaccharide and having a scattering and hatching rate of 50 to 70%
The extract obtained by hot-water extraction with 10 times the weight of distilled water and concentrating the obtained hot-water extract solution at a ratio of 1/50 to 1/60, followed by lyophilization, has an effective concentration of 250 to 350 mg / kg Extract of cricket containing ginsenoside-based saponin and ginseng polysaccharide.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150066834A KR101716763B1 (en) | 2015-05-13 | 2015-05-13 | Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150066834A KR101716763B1 (en) | 2015-05-13 | 2015-05-13 | Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20160133811A KR20160133811A (en) | 2016-11-23 |
KR101716763B1 true KR101716763B1 (en) | 2017-03-15 |
Family
ID=57541503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020150066834A KR101716763B1 (en) | 2015-05-13 | 2015-05-13 | Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR101716763B1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101755167B1 (en) | 2016-09-26 | 2017-07-19 | 유남재 | Functional cricket feed |
USD841898S1 (en) | 2017-04-13 | 2019-02-26 | Aspire Food Group USA Inc. | Insect habitat stacker |
US10638788B2 (en) | 2016-05-04 | 2020-05-05 | Aspire Food Group USA Inc. | Method and system for spray drying insects |
US11395474B2 (en) | 2016-05-10 | 2022-07-26 | Aspire Food Group Ltd | Harvesting and incubating systems for cultivation of insects |
KR20230072595A (en) | 2021-11-18 | 2023-05-25 | 박준열 | A method for cultivating tangor containing saponins |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102070802B1 (en) * | 2017-07-28 | 2020-01-29 | 한국 한의학 연구원 | Composition for improving skin wrinkle or skin moisturizing comprising Gryllus bimaculatus extract as effective component |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3012117B2 (en) * | 1992-07-27 | 2000-02-21 | エイケイ スティール コーポレイション | Controlled material flow hydraulic forming method and apparatus |
KR101391130B1 (en) | 2012-11-05 | 2014-05-07 | 원광대학교산학협력단 | Functional insect feed to increase the growth and nutritional components of insect |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0312117A (en) * | 1989-06-12 | 1991-01-21 | Masaharu Misu | Disposable roll paper type stool seat cover and paper slide type clean stool seat |
JPH0475558A (en) * | 1989-11-17 | 1992-03-10 | Michinari Shimoda | Green feed-containing feed for larva of coleoptera insect and production thereof |
KR100599460B1 (en) * | 2004-06-30 | 2006-07-12 | 윤치영 | Food composition comprising of extracts of cricket having protective effects against hepatotoxicity |
KR20130017746A (en) | 2011-08-11 | 2013-02-20 | 박지호 | Cricket, a mole cricket, cicada larva manufacturing method that contains a pill |
-
2015
- 2015-05-13 KR KR1020150066834A patent/KR101716763B1/en active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3012117B2 (en) * | 1992-07-27 | 2000-02-21 | エイケイ スティール コーポレイション | Controlled material flow hydraulic forming method and apparatus |
KR101391130B1 (en) | 2012-11-05 | 2014-05-07 | 원광대학교산학협력단 | Functional insect feed to increase the growth and nutritional components of insect |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10638788B2 (en) | 2016-05-04 | 2020-05-05 | Aspire Food Group USA Inc. | Method and system for spray drying insects |
US11026439B2 (en) | 2016-05-04 | 2021-06-08 | Aspire Food Group Ltd | Method and system for spray drying insects |
US11395474B2 (en) | 2016-05-10 | 2022-07-26 | Aspire Food Group Ltd | Harvesting and incubating systems for cultivation of insects |
KR101755167B1 (en) | 2016-09-26 | 2017-07-19 | 유남재 | Functional cricket feed |
USD841898S1 (en) | 2017-04-13 | 2019-02-26 | Aspire Food Group USA Inc. | Insect habitat stacker |
KR20230072595A (en) | 2021-11-18 | 2023-05-25 | 박준열 | A method for cultivating tangor containing saponins |
Also Published As
Publication number | Publication date |
---|---|
KR20160133811A (en) | 2016-11-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101716763B1 (en) | Breeding Method for Crickets Comprising Ginsenoside Type Saponin and Polysaccharide from Panax ginseng and their Extracts and Food Composition | |
KR101949105B1 (en) | Chicken feed composition and preparing method thereof | |
KR101723206B1 (en) | Pills for health supplement food comprising extracts of protaetia brebitarsis larba and manufacturing method for the same | |
KR20120107557A (en) | Rice bran fermentation extracts with chlorophyll and the manufacturing method thereof | |
CN104222658A (en) | Nutritional feed for medicinal leeches and preparation method for nutritional feed | |
US10695389B2 (en) | Method for preparing ginseng polysaccharide for immune stimulation and ginseng polysaccharide for immune stimulation prepared therefrom | |
KR101751398B1 (en) | Composition comprising Angelica gigas Nakai, Cornus officinalis, Cervi Parvum Cornu, Red ginseng, Rehmanniae Radix Preparata, Aquilaria agallocha Roxburgh and Honey for anti-inflammation | |
CN113056204A (en) | Livestock feed additive | |
Abd El-Hack et al. | Pharmacological, nutritional and antimicrobial uses of Moringa oleifera Lam. leaves in poultry nutrition: an updated knowledge | |
JP6534443B2 (en) | Method for producing bamboo fermented extract and method for producing immunostimulatory food composition or immunostimulant | |
KR20170024321A (en) | The process of making healthcare compositions comprising fermented Dendropanax morbifera extracts and herbal medicines Abalone extracts | |
KR100725926B1 (en) | Feed containing garlic for chicken | |
KR102012751B1 (en) | Platycodon grandiflorum extract animal feed additive and animal feed | |
CN105360597B (en) | A kind of functional pharmaceutical chemistry and preparation method thereof and feeding method promoting soft-shelled turtle quality | |
KR102572979B1 (en) | Composition for preventing of treating sarcopenia or muscular dystrophy containing Tenbrio molitor and balloon-flower extract | |
KR102172369B1 (en) | Method for producing functional eggs by feeding barley sprouts and functional eggs produced by the above method | |
KR100948281B1 (en) | The method of preparing the functional food for diet using extractive extracted from madicin-materials of plants | |
KR101871115B1 (en) | PHARMACEUTICAL COMPOSITION CONTAINING ELAEAGNUS MULTRIFLORA Thunb. EXTRACT FOR IMMUNE-ENHANCING | |
CN102715396A (en) | Special diet formula containing chitosan oligosaccharide and oligopeptide for hepatopaths | |
KR101773322B1 (en) | PHARMACEUTICAL COMPOSITION CONTAINING ELAEAGNUS MULTRIFLORA Thunb. EXTRACT FOR IMMUNE-ENHANCING | |
JP3507115B2 (en) | Banaba leaf extract and antidiabetic agent | |
KR101938933B1 (en) | Compositions for alleviating, preventing or treating inflammatory Pain comprising extract from Chaenomeles sinensis and Glycyrrhizae and Aralia elata | |
KR20220006183A (en) | Feed additive using herbal medicine and method for manufacturing thereof | |
JP2003252775A (en) | Nk cell activation agent | |
JP2008230991A (en) | BIOLOGICALLY ACTIVE COMPOSITION ORIGINATED FROM SPARASSIS CRISPA Wulf:Fr. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
GRNT | Written decision to grant |