KR101679084B1 - 신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법 - Google Patents

신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법 Download PDF

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KR101679084B1
KR101679084B1 KR1020107028713A KR20107028713A KR101679084B1 KR 101679084 B1 KR101679084 B1 KR 101679084B1 KR 1020107028713 A KR1020107028713 A KR 1020107028713A KR 20107028713 A KR20107028713 A KR 20107028713A KR 101679084 B1 KR101679084 B1 KR 101679084B1
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KR20110018381A (ko
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스테펜 브랜드
치-시웅 초우
머레이 무-영
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아고스 쎄라퓨틱스, 인코포레이티드
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    • C07ORGANIC CHEMISTRY
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KR1020107028713A 2008-05-23 2009-05-22 신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법 Expired - Fee Related KR101679084B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12870908P 2008-05-23 2008-05-23
US61/128,709 2008-05-23
PCT/US2009/003174 WO2009142759A1 (en) 2008-05-23 2009-05-22 Novel soluble cd83 polypeptides, formulations and methods of use

Related Child Applications (1)

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KR1020167023212A Division KR20160104101A (ko) 2008-05-23 2009-05-22 신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법

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KR20110018381A KR20110018381A (ko) 2011-02-23
KR101679084B1 true KR101679084B1 (ko) 2016-11-24

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KR1020107028713A Expired - Fee Related KR101679084B1 (ko) 2008-05-23 2009-05-22 신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법
KR1020167023212A Ceased KR20160104101A (ko) 2008-05-23 2009-05-22 신규 가용성 cd83 폴리펩티드, 제형 및 사용 방법

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US (1) US20110182903A1 (enExample)
EP (1) EP2288387B1 (enExample)
JP (1) JP2011520959A (enExample)
KR (2) KR101679084B1 (enExample)
CN (1) CN102036690B (enExample)
AU (1) AU2009249540B9 (enExample)
BR (1) BRPI0913577B1 (enExample)
CA (1) CA2725198A1 (enExample)
IL (1) IL209207A (enExample)
MX (1) MX2010012576A (enExample)
RU (1) RU2535340C2 (enExample)
WO (1) WO2009142759A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1422241A1 (en) 2002-11-19 2004-05-26 Alexander Steinkasserer Use of soluble forms of CD83 and nucleic acids encoding them for the treatment or prevention of diseases
US9102726B2 (en) * 2002-12-04 2015-08-11 Argos Therapeutics, Inc. Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same
US7169898B2 (en) 2002-12-04 2007-01-30 Alexander Steinkasserer Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells
CN103243119B (zh) * 2013-05-20 2016-03-30 中国科学技术大学 可溶性cd83的表达和制备方法
US20190315878A1 (en) 2016-11-07 2019-10-17 Argos Therapeutics Inc. Bispecific antibodies that modulate tlr-4 signaling and uses thereof
ES2954311T3 (es) 2017-04-01 2023-11-21 Avm Biotechnology Llc Reemplazo de un preacondicionamiento citotóxico antes de una inmunoterapia celular
KR102282341B1 (ko) 2018-09-12 2021-07-27 아주대학교산학협력단 Cd83 억제제를 유효성분으로 포함하는 베체트병의 예방 또는 치료용 조성물
EP3895723A1 (en) * 2020-04-16 2021-10-20 Friedrich-Alexander-Universität Erlangen-Nürnberg Scd83 for wound healing, hair growth, and skin and hair care
DE102024110866A1 (de) 2024-04-18 2025-10-23 Christian Arnold Pharmazeutische Zusammensetzung zur Heilung einer Wunde

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004046182A2 (en) * 2002-11-19 2004-06-03 Argos Therapeutics, Inc. Use of soluble forms of cd83 and nucleic acids encoding them for the treatment or prevention of diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US5316920A (en) * 1992-04-17 1994-05-31 Dana-Faber Cancer Institute, Inc. Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
US5710262A (en) * 1992-04-17 1998-01-20 Dana-Faber Cancer Institute, Inc. Nucleic acid encoding HB15 polypeptides
KR20010023325A (ko) * 1997-08-26 2001-03-26 리스 데브라 케이. 함지방세포-특이적 단백질 상동체
PT1223971E (pt) 1999-10-27 2005-10-31 Alexandra Lucas Composicoes e metodos para prevencao e tratamento da rejeicao de transplante
US20020014242A1 (en) * 2000-07-31 2002-02-07 Abraham Scaria Use of rapamycin to inhibit immune response and induce tolerance to gene therapy vector and encoded transgene products
US20040185040A1 (en) * 2001-11-21 2004-09-23 Celltech R & D Limited Modulating immune responses
US20030219436A1 (en) * 2002-03-15 2003-11-27 Ledbetter Jeffrey A. Compositions and methods to regulate an immune response using CD83 gene expressed in tumors and using soluble CD83-Ig fusion protein
EP1578366A4 (en) * 2002-10-09 2007-12-19 Tolerrx Inc MOLECULES PREFERABLY ASSOCIATED WITH EFFECTOR T CELLS OR REGULATORY T CELLS AND METHODS OF USE THEREOF
US9102726B2 (en) 2002-12-04 2015-08-11 Argos Therapeutics, Inc. Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same
US7169898B2 (en) * 2002-12-04 2007-01-30 Alexander Steinkasserer Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells
EP2789625B1 (en) * 2006-08-18 2018-06-06 Argos Therapeutics, Inc. Use of soluble CD83 for perfusing a tissue for transplantation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004046182A2 (en) * 2002-11-19 2004-06-03 Argos Therapeutics, Inc. Use of soluble forms of cd83 and nucleic acids encoding them for the treatment or prevention of diseases

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Publication number Publication date
AU2009249540B9 (en) 2014-09-18
EP2288387A4 (en) 2011-04-27
CN102036690B (zh) 2013-11-06
KR20110018381A (ko) 2011-02-23
CA2725198A1 (en) 2009-11-26
RU2010152553A (ru) 2012-06-27
AU2009249540A8 (en) 2011-01-20
BRPI0913577B1 (pt) 2022-05-31
KR20160104101A (ko) 2016-09-02
HK1155066A1 (en) 2012-05-11
EP2288387B1 (en) 2013-02-13
AU2009249540A1 (en) 2009-11-26
RU2535340C2 (ru) 2014-12-10
US20110182903A1 (en) 2011-07-28
EP2288387A1 (en) 2011-03-02
BRPI0913577A2 (pt) 2020-08-18
MX2010012576A (es) 2011-04-05
IL209207A0 (en) 2011-01-31
IL209207A (en) 2014-05-28
AU2009249540B2 (en) 2014-07-03
WO2009142759A1 (en) 2009-11-26
CN102036690A (zh) 2011-04-27
JP2011520959A (ja) 2011-07-21

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