KR101539700B1 - 연골세포 유래 세포외 기질막을 이용한 신생혈관질환 치료용 조성물 및 각막 또는 결막 이식재 - Google Patents

연골세포 유래 세포외 기질막을 이용한 신생혈관질환 치료용 조성물 및 각막 또는 결막 이식재 Download PDF

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KR101539700B1
KR101539700B1 KR1020130106092A KR20130106092A KR101539700B1 KR 101539700 B1 KR101539700 B1 KR 101539700B1 KR 1020130106092 A KR1020130106092 A KR 1020130106092A KR 20130106092 A KR20130106092 A KR 20130106092A KR 101539700 B1 KR101539700 B1 KR 101539700B1
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Prior art keywords
cartilage
extracellular matrix
corneal
cells
cell
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KR1020130106092A
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English (en)
Korean (ko)
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KR20140031814A (ko
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민병현
박소라
최병현
양재욱
윤정호
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아주대학교산학협력단
리젠프라임 주식회사
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Priority to PCT/KR2013/008018 priority Critical patent/WO2014038866A1/ko
Priority to CN201380057870.6A priority patent/CN104837494A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Cell Biology (AREA)
  • Cardiology (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
KR1020130106092A 2012-09-05 2013-09-04 연골세포 유래 세포외 기질막을 이용한 신생혈관질환 치료용 조성물 및 각막 또는 결막 이식재 KR101539700B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/KR2013/008018 WO2014038866A1 (ko) 2012-09-05 2013-09-05 연골세포 유래 세포외 기질막을 이용한 신생혈관질환 치료용 조성물 및 각막 또는 결막 이식재
CN201380057870.6A CN104837494A (zh) 2012-09-05 2013-09-05 使用软骨来源细胞的胞外基质膜的治疗血管生成疾病的组合物、以及角膜或结膜的移植物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020120097973 2012-09-05
KR20120097973 2012-09-05

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KR20140031814A KR20140031814A (ko) 2014-03-13
KR101539700B1 true KR101539700B1 (ko) 2015-07-28

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101948156B1 (ko) * 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
KR20210058357A (ko) 2019-11-14 2021-05-24 경북대학교 산학협력단 각막 또는 공막 이식용 다겹 양막 시트

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* Cited by examiner, † Cited by third party
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KR102440051B1 (ko) 2014-03-21 2022-09-06 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 세포외 기질로부터 유래한 최종 멸균된 하이드로겔의 제조 방법
KR101633585B1 (ko) * 2014-03-31 2016-06-27 아주대학교산학협력단 표면개질된 연골세포 유래 세포외 기질막을 유효성분으로 함유하는 유착방지용 조성물
WO2015152596A1 (ko) * 2014-03-31 2015-10-08 아주대학교산학협력단 표면개질된 연골세포 유래 세포외 기질막을 유효성분으로 함유하는 유착방지용 조성물
WO2017123883A1 (en) * 2016-01-13 2017-07-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Vascular extracellular matrix hydrogel
KR102114787B1 (ko) 2018-04-02 2020-05-26 중앙대학교 산학협력단 리보핵산분해효소 5 고발현된 각막 내피세포를 포함하는 3차원 각막 내피 이식체 제조방법
CN110025402B (zh) * 2019-05-21 2021-09-24 王丽强 含生物材料的人工角膜
CN113117146B (zh) * 2021-03-29 2022-01-28 中国人民解放军总医院第一医学中心 一种用于人工角膜的支架及其制备方法
CN115944781A (zh) * 2021-10-09 2023-04-11 上海软馨生物科技有限公司 一种基于3d打印的软骨组织工程复合物及其用途

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KR100816395B1 (ko) * 2006-09-21 2008-03-27 (주)필미아젠 세포 유래 세포외기질막의 제조방법
KR20100005105A (ko) * 2007-05-06 2010-01-13 민병현 세포외 기질 지지체를 이용한 연골질환 치료용 조성물

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AU652744B2 (en) * 1990-01-25 1994-09-08 Children's Medical Center Corporation Method and compositions for inhibiting angiogenesis
CN1202932A (zh) * 1995-10-23 1998-12-23 儿童医学中心公司 治疗用抗血管生成的组合物和方法
US6168807B1 (en) * 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
TWI407967B (zh) * 2006-04-28 2013-09-11 Ray Jui Fang Tsai 人類角膜內皮幹細胞之擴增方法
KR101056069B1 (ko) * 2008-10-13 2011-08-10 아주대학교산학협력단 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법
CN102188748B (zh) * 2011-04-29 2014-02-26 成都军区昆明总医院 一种新型软骨细胞外基质膜及其制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100816395B1 (ko) * 2006-09-21 2008-03-27 (주)필미아젠 세포 유래 세포외기질막의 제조방법
KR20100005105A (ko) * 2007-05-06 2010-01-13 민병현 세포외 기질 지지체를 이용한 연골질환 치료용 조성물

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101948156B1 (ko) * 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
KR20210058357A (ko) 2019-11-14 2021-05-24 경북대학교 산학협력단 각막 또는 공막 이식용 다겹 양막 시트

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CN104837494A (zh) 2015-08-12

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