KR101500766B1 - 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 - Google Patents

치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 Download PDF

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KR101500766B1
KR101500766B1 KR1020097011731A KR20097011731A KR101500766B1 KR 101500766 B1 KR101500766 B1 KR 101500766B1 KR 1020097011731 A KR1020097011731 A KR 1020097011731A KR 20097011731 A KR20097011731 A KR 20097011731A KR 101500766 B1 KR101500766 B1 KR 101500766B1
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dimethoxy
isobutyl
hexahydro
pyrido
isoquinolin
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KR101500766B9 (ko
KR20090079257A (ko
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카일 더블유. 가노
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뉴로크린 바이오사이언시즈 인코퍼레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020097011731A 2006-11-08 2007-11-08 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 Active KR101500766B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86494406P 2006-11-08 2006-11-08
US60/864,944 2006-11-08
PCT/US2007/084176 WO2008058261A1 (en) 2006-11-08 2007-11-08 Substituted 3-isobutyl-9, 10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a] isoquinolin-2-ol compounds and methods relating thereto

Publications (3)

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KR20090079257A KR20090079257A (ko) 2009-07-21
KR101500766B1 true KR101500766B1 (ko) 2015-03-16
KR101500766B9 KR101500766B9 (ko) 2024-09-25

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KR1020097011731A Active KR101500766B1 (ko) 2006-11-08 2007-11-08 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법

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US (2) US8039627B2 (https=)
EP (1) EP2081929B1 (https=)
JP (1) JP5290185B2 (https=)
KR (1) KR101500766B1 (https=)
CN (1) CN101553487B (https=)
AU (1) AU2007317242B2 (https=)
BR (1) BRPI0718247B1 (https=)
CA (1) CA2668689C (https=)
DK (1) DK2081929T3 (https=)
EA (1) EA018378B1 (https=)
ES (1) ES2402220T3 (https=)
IL (1) IL198250A0 (https=)
MX (1) MX2009004910A (https=)
PL (1) PL2081929T3 (https=)
PT (1) PT2081929E (https=)
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AU2007317242B2 (en) 2013-08-01
ES2402220T3 (es) 2013-04-29
US8039627B2 (en) 2011-10-18
EP2081929B1 (en) 2013-01-09
IL198250A0 (en) 2009-12-24
US8357697B2 (en) 2013-01-22
KR101500766B9 (ko) 2024-09-25
CA2668689A1 (en) 2008-05-15
PT2081929E (pt) 2013-04-15
JP2010509366A (ja) 2010-03-25
CN101553487A (zh) 2009-10-07
DK2081929T3 (da) 2013-04-15
AU2007317242A1 (en) 2008-05-15
EP2081929A1 (en) 2009-07-29
PL2081929T3 (pl) 2013-06-28
MX2009004910A (es) 2009-07-24
CN101553487B (zh) 2012-06-13
EA200970461A1 (ru) 2009-12-30
WO2008058261A1 (en) 2008-05-15
ES2402220T8 (es) 2021-12-23
BRPI0718247A2 (pt) 2014-01-07
US20120077839A1 (en) 2012-03-29
CA2668689C (en) 2015-12-29
KR20090079257A (ko) 2009-07-21
BRPI0718247B1 (pt) 2021-09-21
US20080167337A1 (en) 2008-07-10
EA018378B1 (ru) 2013-07-30
JP5290185B2 (ja) 2013-09-18

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