KR101480688B1 - Cosmetic composition for improving the skin elasticity - Google Patents

Abstract

The present invention relates to a cosmetic composition which is applied to skin to improve the elasticity of skin and improve wrinkles. More particularly, the present invention relates to a cosmetic composition containing a water-soluble film former, a polyhydric alcohol, a polar oil, To a cosmetic composition that provides a sense of resilience and allows the efficacious material to be effectively absorbed into the skin, thereby improving the dermal-epidermal layer with continued use and ultimately improving skin elasticity.

Microgels, water-soluble film formers, polyhydric alcohols, polar oils, ester oils, skin elasticity, wrinkles

Description

[0001] Cosmetic composition for improving skin elasticity [

The present invention relates to a cosmetic composition containing a water-soluble film former, a polyhydric alcohol, a polar oil, and a resilience improving effect ingredient to improve skin elasticity and improve wrinkles.

Skin elasticity is manifested by elastic fibers composed of elastin present in the dermis. Such elastic fibers have a very low elastic modulus like rubber, so they are easily deformed by small forces, and when they are removed Return to the circle. In addition, the elastic fibers have the form of microfibrils embedded in an amorphous matrix called elastin. Elastin is a very unique material found only in the elastic fibers of lysine, desmosine and isodesmosine It is a protein composed of amino acids. These desmosins and isodesmesynes form cross-links in long peptide chains, which makes elastin behave like a rubber.

In addition, elastic fibers composed of elastin are present along with collagen fibers called collagen, and it is possible to maintain skin elasticity in the state where elastin and collagen are sufficiently present.

On the other hand, lowering of skin elasticity is caused by degradation and destruction of elastin due to attenuation of skin cells (fibroblasts) caused by aging and ultraviolet rays. Ultraviolet rays are used to express elastin degradation enzymes in the skin. This enzyme decomposes normal elastin in the skin, resulting in reduced skin elasticity. In addition, skin elasticity deterioration is caused by damage and generation of a protein called collagen which constitutes 70% or more of the skin dermis. Collagen is also degraded by a degrading enzyme called collagenase, which is caused by ultraviolet rays.

Conventional techniques generally use an efficacious ingredient that inhibits the activity of collagenase or inhibits the activity of elastase for skin elasticity increasing effect. These techniques do not give an immediate feeling of elasticity to the skin, but merely use an effective ingredient, which has a limitation in that the active ingredient is effectively absorbed into the skin and exerted its efficacy.

Therefore, it is an urgent and important issue to develop cosmetics that have a low elasticity for existing skin elasticity improvement products, provide immediate elasticity, and have excellent skin elasticity and promoting effect.

Accordingly, the present inventors have developed a cosmetic composition which gives a skin elasticity and a perceivable effect on skin elasticity, moisturizing and wrinkle improvement by continuous use, and also has a skin barrier function, barrier function, skin permeability, The inventors of the present invention discovered the differences depending on the components and the contents, and completed the present invention.

Accordingly, it is an object of the present invention to provide a skin-elastic film to provide a feeling of elasticity to the skin so that the elasticity-improving effective ingredient can be effectively absorbed to the skin and sufficiently exhibit the effect, thereby softening the stratum corneum, And to provide a cosmetic composition which is effective in improving skin elasticity by enhancing delivery of an active ingredient through the skin.

In order to achieve the above object, the present invention provides a cosmetic composition for enhancing skin elasticity containing a water-soluble film former, a polyhydric alcohol, a polar oil and a elasticity-improving effect ingredient.

The cosmetic composition for skin elasticity enhancement according to the present invention contains a water-soluble film former, a polyalcohol, a polar oil and a elasticity-improving effect ingredient in an amount of more than a predetermined amount to provide an immediate elasticity to the skin, And improving the dermal-epidermal layer by continuous use, ultimately improving skin elasticity.

The skin elasticity-enhancing cosmetic composition of the present invention contains a water-soluble film former, a polyhydric alcohol, a polar oil, and a resilience improving effect ingredient.

Hereinafter, the present invention will be described in more detail.

In the cosmetic composition according to the present invention, a water-soluble film former is used in order to impart an immediate feeling of elasticity to the skin and to moisturize through the formation of a flexible skin barrier and to promote absorption of the active ingredient.

The water-soluble film former is contained in an amount of 0.01 to 10.0% by weight, preferably 0.1 to 2.0% by weight, based on the total weight of the composition. If it is contained in an amount less than 0.01% by weight, a desired film feeling can not be obtained, and if it is contained in an amount exceeding 10.0% by weight,

Examples of the water-soluble film former used in the present invention include acrylamide, acrylic acid, polyvinyl acetate, polyquaternium and polysaccharide polymers or copolymers thereof. Specific examples thereof include hydroxyethyl acrylate / sodium acrylate Polyvinyl pyrrolidone vinyl acetate copolymer, polyquaternium hydroxyethyl cellulose, hydroxypropyl methylcellulose, hydroxypropyl cellulose, hydroxypropyl guar, and the like. One or more of them may be selected and used.

Further, in the cosmetic composition of the present invention, a polyhydric alcohol is used as a moisturizing component to soften the horny substance and to soften the epidermal interstitial lipid component so that the active ingredient is absorbed and diffused through the skin well.

The polyhydric alcohol is contained in an amount of 1.0 to 40.0% by weight, preferably 10.0 to 20.0% by weight based on the total weight of the composition. If it is contained in an amount of less than 1.0% by weight, desired softening and moisturizing effects can not be obtained. If it is contained in an amount of more than 40.0% by weight,

Specific examples thereof include glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, polyethylene glycol, sorbitol and the like, and at least one of them may be selected and used.

In the cosmetic composition of the present invention, natural oils or synthetic oils may be used as the oil component, and hydrocarbons, triglycerides, esters or silicone oils may be used. The oil component is contained in an amount of 1.0 to 40.0% by weight, preferably 5.0 to 20.0% by weight based on the total weight of the composition. If it is contained in an amount of less than 1.0% by weight, it is difficult to obtain a desired emulsion formulation. If it exceeds 40.0% by weight, stability of the emulsifier type is deteriorated .

The use of an appropriate amount of the polar oil in the above-mentioned oils makes it possible to soften the keratin and increase the penetration of the contents into the skin, so that the elasticity improving effect ingredient can be more evenly and deeply penetrated into the skin, thereby inhibiting the activity of collagenase or elastase The efficacy becomes high. Therefore, in the cosmetic composition according to the present invention, the polar oil is contained in an amount of 1.0 to 20.0% by weight, preferably 3.0 to 10.0% by weight based on the total weight of the composition. If it is contained in an amount of less than 1.0% by weight, it is difficult to obtain a desired skin absorption enhancing effect, and if it exceeds 20.0% by weight, stability of the emulsifier type is deteriorated .

The polar oils used in the present invention are particularly ester oils, and more specifically, isopropyl myristate, isopropyl palmitate, cetyl ethylhexanoate, alkyl benzoates having 12 to 15 carbon atoms, dicaprylyl carbonate, pentaerythritol But are not limited to, at least one selected from the group consisting of tetraethylhexanoate, pentaerythrityl tetraisostearate and diisostearyl malate.

The cosmetic composition according to the present invention contains a skin elasticity improving effect ingredient. Specific examples include oleanolic acid, retinol, adenosine, and peptides, and at least one of them may be selected and used. In the present invention, the oleanolic acid is used in an amount of 0.05% by weight based on the total weight of the composition.

The cosmetic composition according to the present invention may be formulated into an oil-in-water (O / W) or water-in-oil (W / O) emulsion and may be formulated into lotions, creams, milks, patches, sticks or sprays.

Hereinafter, the present invention will be described in more detail with reference to examples and test examples. However, these examples and test examples are provided only to aid understanding of the present invention, and the scope of the present invention in any sense is not limited to these examples.

[Reference Example] Preparation of cosmetics for skin elasticity enhancement

As shown in the following Table 1, the cosmetic composition containing oleanolic acid as in Examples 1 to 7 and Comparative Examples 1 to 2 (oil-in-water emulsion) containing different amounts of polar oil, polyhydric alcohol and film- (O / W) emulsion formulation). Comparative Example 1 is an example of producing a basic O / W emulsion base, and Comparative Example 2 is obtained by adding an oleanolic acid to Comparative Example 1. Example 1 is an example containing a polyhydric alcohol in the prescription of Comparative Example 2, and Example 2 is an example in which the type and content of a polyhydric alcohol is increased than that of Example 1. Example 3 was prepared by adding a hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, which is a water-soluble film former, to the formulation of Comparative Example 2, Example 4 is a water-soluble film former in the formulation of Comparative Example 2 And polyvinylpyrrolidone. Examples 5 and 6 use an ester oil which is a polar oil in place of the hydrocarbon oil in the prescription of Comparative Example 2. In Example 7, the polyhydric alcohol, the film forming agent and the polar oil were all used in the prescription of Comparative Example 2.

division Raw material name Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Comparative Example 1 Comparative Example 2 Awards
ingredient Purified water To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 Disodium edetate 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 glycerin 5 5 - - - - 5 - - Butylene glycol - 10 - - - - 10 - - Hydroxyethyl acrylate /
Sodium acryloyldimethyl
Taurate copolymer - - 0.5 - - - 0.5 - - Polyvinylpyrrolidone - - - 0.5 - - - - - Paid
ingredient Cetyl alcohol 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Cetearyl Alcohol /
Cetearyl glucoside 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Glyceryl stearate /
FAGE -100 stearate 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Pentaerythritol
Tetraethylhexanoate - - - - 15 15 - - Cetyl ethylhexanoate - - - - - 15 - - - Hydrogenated polyhedrin 15 15 15 15 - - - 15.0 15.0 Base Ethyl alcohol 0.3 0.3 0.3 0.3 0.3 0.3 0.3 - 0.3 Propylene glycol 0.1 0.1 0.1 0.1 0.1 0.1 0.1 - 0.1 Oleanolic acid 0.05 0.05 0.05 0.05 0.05 0.05 0.05 - 0.05 Etc antiseptic Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Spices Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount

≪ Preparation methods of Examples 1 to 7 and Comparative Examples 1 and 2 >

(1) The aqueous phase components are homogeneously mixed and dissolved by heating at 70 ° C.

(2) The oil components are mixed and dissolved by heating at 75 占 폚.

(3) While stirring (homomixing) at 70 캜, the above (2) is gradually added to the above (1) to form an oil-in-water (oil-in-water emulsion) formulation.

(4) The oleanolic acid base is dissolved by stirring at 60 캜, and then cooled to 40 캜 or lower.

(5) After the above-mentioned (3) is cooled to 40 캜 or lower, the above-mentioned (4) is added and stirred to homogeneously mix.

[Test Example 1] Promotion of collagen production promotion

The effect of inhibiting collagenase activity was measured by treating samples of human fibroblasts collected directly from humans or commercially. The contents prepared in the prescriptions of Comparative Examples 1 and 2 were used as a sample, and the experimental method was as follows.

Human fibroblasts were placed in a culture flask and cultured until they were about 70-80% grown. After the sample was treated for 1 day, the cell culture medium was collected and the degree of collagen production was measured using a commercially available collagenase activity measuring apparatus (Anal Biochem 116 (1): 172-7, 1987). An assay of collagenase activity using enzyme-linked immunosorbent assay for mammalian collagenase "). That is, Matrix Metalloproteinase-1 (MMP-1), an enzyme that degrades collagen derived from human, was quantified using an antibody against collagenase. The results are shown in Table 2 below.

sample Active inhibition (%) Comparative Example 1 0 Comparative Example 2 48

In Comparative Example 2, since the composition of Comparative Example 1 further contains an oleanolic acid, the collagen production promoting effect of the oleanolic acid can be confirmed from Table 2 above.

In fact, in order to effectively absorb the elasticity-improving effect ingredients such as oleanolic acid when applied to human skin, the emulsion formulations are generally more advantageous for skin absorption than the solubilized formulations. Therefore, in the following test, the factors affecting the elasticity improvement effect in the oil-in-water emulsion formulation were identified and the influence thereof was confirmed.

[Test Example 2] Effect of improving the elasticity of water-soluble film former

In order to confirm the immediate skin elasticity improvement effect after using the product, the cream formulation having the compositions of Examples 3 and 4 and Comparative Example 2 was applied to 20 Korean women in their thirties and immediately evaluated the feeling of use. The results are shown in Table 3 below.

Feeling item Comparative Example 2 Example 3 Example 4 I feel like putting up stained skin. - 8 6 I feel a firm sense of skin 8 12 10 I do not know. 12 - 4

Table 3 shows that when the water-soluble polymer was used, the skin elasticity was immediately felt, and that the hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer was evaluated more favorably than the vinyl pyrrolidone. In the case of hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, a film is formed in the form of microgels to form a flexible film on the skin, thereby showing a feeling of greater skin elasticity.

[Test Example 3] Skin elasticity enhancing effect

In order to measure the skin elasticity enhancement effect after using the product, the elasticity of the skin was measured using a cutometer (Cutometer, Courage + Khazaka Electronic GmbH, Cologne, Germany) Respectively. The skin elasticity of 60 Korean women in their 30s was measured and 36 women with an average value of 0.7 ~ 0.73 were selected. Again, four individuals having an average value of 0.71 were grouped into nine groups, and the compositions of Examples 1 to 7 and Comparative Examples 1 and 2 were used, respectively. Skin elasticity and skin elasticity recovery after 4 weeks of use were measured. Table 4 and FIG. 1 show the measured values of total skin elasticity by subject after 4 weeks use, and Table 5 and FIG. 2 show skin elasticity recovery by subjects after 4 weeks use.

Total skin elasticity after 4 weeks use Before use Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Comparative Example 1 Comparative Example 2 Measures
(AU) 0.712 0.783 0.816 0.802 0.781 0.778 0.774 0.847 0.723 0.752

Skin elasticity recovery after 4 weeks use Before use Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Comparative Example 1 Comparative Example 2 Measures
(AU) 0.245 0.292 0.305 0.298 0.291 0.289 0.284 0.317 0.252 0.272

Table 4 and Table 5 show that skin elasticity and skin elasticity recovery were both improved after using Examples 1 to 7 and Comparative Examples 1 and 2. However, when Examples 1 to 7 were used, It is found that the skin elasticity and the elastic recovery are more excellent than those in the case of using.

The skin elasticity and skin elasticity recovery of Examples 1 and 2 are higher than that of Comparative Example 2, and skin absorption of the active substance is increased according to the use of the polyhydric alcohol, thereby improving skin elasticity. Also, since the measurement value of Example 2 is higher than that of Example 1, it can be seen that the effect is greatly increased when the polyhydric alcohol is used in an amount of 10 wt% or more.

In addition, in Examples 3 and 4, the skin elasticity and the skin elasticity recovery were higher than those of Comparative Example 2, and the use of the water-soluble film former resulted in the formation of a film on the skin, Able to know. Also, when the hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer was used because the measurement value of Example 3 was higher than that of Example 4, a microgel type thick and elastic film was formed and polyvinylpyrrolidone It is found that the effect is higher than in the case of using.

In addition, in Examples 5 and 6, the skin elasticity and skin elasticity recovery were higher than that of Comparative Example 2, so that the use of the polar oil softens the keratin and smoothes the intercellular lipids of the skin layer, Diffusion is promoted. The difference between the measured values of Examples 5 and 6 is not so large, so that there is almost no difference in the result depending on the difference in the ester oil contained.

In Example 7, skin elasticity and skin elasticity recovery after four weeks of use were much higher than those of Examples 1 to 6 and Comparative Examples 1 and 2. From this, it can be seen that when the water-soluble film former, the polyhydric alcohol and the polar oil are used together in a specific amount or more, the skin elasticity-enhancing effect is greatly increased.

[Test Example 4] Density enhancement of skin dermis

Dermis thickness and density were measured on the cheek surface of the facial area using Dermascan C (Cortex, Denmark). We measured the skin density of 60 Korean women in their thirties and selected 36 women with an average of 23.0 ~ 23.2%. Again, four individuals having an average value of about 23.1% were grouped into nine groups, and the compositions of Examples 1 to 7 and Comparative Examples 1 and 2 were used, respectively. After 4 weeks of use, changes in dermal layer thickness and dermal density were measured. Table 6 and FIG. 3 show changes in dermal layer thickness after 4 weeks of use, and Table 7 and FIG. 4 show the dermal density of each subject after 4 weeks of use.

Changes in dermal layer thickness after 4 weeks use Before use Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Comparative Example 1 Comparative Example 2 Street
(AU) 1.35 1.68 1.71 1.7 1.63 1.67 1.59 1.74 1.35 1.48

After 4 weeks use dermal density Before use Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Comparative Example 1 Comparative Example 2 burglar(%) 23.1 24.5 24.7 24.6 24.3 24.3 24.2 24.9 23.3 23.8

Table 6 and Table 7 show that skin dermis thickness and denseness were improved after using Examples 1 to 7 and Comparative Example 2, but when using Examples 1 to 7, skin dermis thickness And the increase in density is greater.

In the case of Examples 1 and 2, the dermal layer thickness and the dermal density are higher than that of Comparative Example 2, indicating that the use of polyhydric alcohol improves the skin absorbency of the active substance, . Also, since the measurement value of Example 2 is higher than that of Example 1, it can be seen that the effect is greatly increased when the polyhydric alcohol is used in an amount of 10 wt% or more.

Further, in Examples 3 and 4, the dermal layer thickness and density of the dermis are higher than that of Comparative Example 2, so that the use of the water-soluble film former results in the formation of a film on the skin, Able to know. Also, when the hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer was used because the measurement value of Example 3 was higher than that of Example 4, a microgel type thick and elastic film was formed and polyvinylpyrrolidone It is found that the effect is higher than in the case of using.

In addition, in Examples 5 and 6, the dermal layer thickness and the dermal density are higher than that of Comparative Example 2, so that the use of the polar oil can soften the keratin and soften the intercellular lipids of the skin layer, Diffusion is promoted.

In Example 7, the change in the thickness of the dermal layer and the dermal density were measured to be much higher than those in Examples 1 to 6 and Comparative Examples 1 and 2 after 4 weeks of use. From these results, it can be seen that when the water-soluble film former, the polyhydric alcohol and the polar oil are used together in a specific amount or more, the thickness of the dermal layer and the density of the dermal layer are greatly increased.

The cosmetic composition for skin elasticity enhancement according to the present invention is not limited to the formulations of the above-mentioned Examples and Comparative Examples, but may be in the form of an oil-in-water (O / W) or water-in-oil (W / O) emulsion, such as lotions, creams, Or as a formulation of a spray.

1 is a graph showing the total skin elasticity after using Examples 1 to 7 and Comparative Examples 1 and 2 for 4 weeks.

FIG. 2 is a graph showing skin elasticity recovery after using Examples 1 to 7 and Comparative Examples 1 and 2 for 4 weeks. FIG.

Fig. 3 is a graph showing changes in dermal layer thickness after using Examples 1 to 7 and Comparative Examples 1 and 2 for 4 weeks. Fig.

4 is a graph showing dermis compactness after using Examples 1 to 7 and Comparative Examples 1 and 2 for 4 weeks.

Claims (10)

A water-soluble film former, a polyhydric alcohol, a polar oil, and an elasticity-improving effective ingredient, wherein the elasticity-improving effective ingredient is at least one selected from the group consisting of oleanolic acid, retinol and adenosine. The cosmetic composition for skin elasticity enhancement according to claim 1, wherein the water-soluble film former is contained in an amount of 0.01 to 10.0% by weight based on the total weight of the composition. The composition of claim 1 wherein the water soluble film former is selected from the group consisting of hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, polyvinylpyrrolidone, vinylpyrrolidone vinyl acetate copolymer, polyquaternium hydroxyethylcellulose, Hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxypropylcellulose, and hydroxypropylgallate. ≪ RTI ID = 0.0 > 21. < / RTI > The cosmetic composition for enhancing skin elasticity according to claim 1, wherein the polyhydric alcohol is contained in an amount of 1.0 to 40.0% by weight based on the total weight of the composition. The cosmetic composition for skin elasticity enhancement according to claim 1, wherein the polyhydric alcohol is at least one selected from the group consisting of glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, polyethylene glycol and sorbitol. The skin elasticity-enhancing composition according to claim 1, wherein the polar oil is contained in an amount of 1.0 to 20.0% by weight based on the total weight of the composition. The cosmetic composition for skin elasticity enhancement according to claim 1, wherein the polar oil is an ester oil. The process of claim 7, wherein the ester oil is selected from the group consisting of isopropyl myristate, isopropyl palmitate, cetyl ethyl hexanoate, alkyl benzoates having from 12 to 15 carbon atoms, dicaprylyl carbonate, pentaerythritol tetraethyl hexanoate, Erythritol tetraisostearate, and diisostearyl malate. The cosmetic composition for skin elasticity enhancement according to claim 1, delete The cosmetic composition according to claim 1, wherein the cosmetic composition is in the form of an oil-in-water (O / W) or water-in-oil (W / O) emulsion and has a formulation of lotion, cream, milky lotion, patch, stick or spray. (EN) Cosmetic composition for promotion.

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