KR101477891B1 - A Composition of Platanus orientalis L extract for anti whitening, wrinkle, aging - Google Patents

Abstract

The present invention relates to the development of highly functional cosmetic raw materials containing cosmetic ingredients for whitening, wrinkling and anti-aging (including ultraviolet cutoff) cosmetic ingredients from Platanus orientalis L. ethanol extracts.

Description

(A Composition of Platanus orientalis L extract for anti-whitening, wrinkle, aging) containing a whitening agent, a wrinkle, an anti-aging agent,

The present invention relates to a cosmetic comprising whitening, wrinkle and anti-aging cosmetics containing sunflower (Platanus orientalis L) ethanol extract. That is, the extract obtained by adding water, a carbonic anhydride or lower alcohol, ethyl acetate, chloroform, n-butanol and 1,3-butylene glycol to the sycamore tree {Platanus orientalis L} is a common basic cosmetic, Lotion, nutritional lotion, nutritional cream, massage cream, essence, pack and so on.

   Melanocytes {Melanocyte} among the cells that constitute the human skin are known to be important cells for synthesizing and releasing melanin to determine skin color. Melanocytes are known to synthesize melanin by ultraviolet light, free radicals, and various other factors to make the skin dull. Especially, the long wavelength of ultraviolet light {UV-A 320 ~ 400nm} is deeply related to the synthesis of melanin in skin, and it has been reported as a main cause of synthesizing melanin in skin. The process of melanin synthesis

Tyrosine is used as a substrate to produce tyrosinase {Tyrosinase} to generate dopaquinone {DOPAquinone}, which undergoes spontaneous reaction and enzymatic reaction from dopaquinone to produce melanin as a copolymer. In order to prevent melanin biosynthesis, it inhibits the activity of tyrosinase during the melanin biosynthesis process, and thus inhibiting the synthesis of melanin is now the basic concept of whitening cosmetics.

The present invention relates to a whitening, wrinkle and anti-aging cosmetic containing Platanus orientalis L. extract extracted from Platanus orientalis L.

     Among the cells that make up human skin, melanocytes (melanocytes)

(Melanin) is synthesized and released to determine the color of skin is known as an important cell. Melanocytes are known to synthesize melanin by ultraviolet light, free radicals, and various other factors to make the skin dull. Especially, UV-A (UV-A 320 ~ 400nm) is deeply related to the synthesis of melanin in the skin, and it has been reported as a main cause of the synthesis of melanin in the skin. The process of melanin synthesis

Tyrosine as a substrate acts on tyrosinase to generate DOPAquinone. Dopaquinone is spontaneously reacted and enzymatically reacted to produce melanin, which is a copolymer. In order to prevent melanin biosynthesis, the inhibition of the activity of tyrosinase during the melanin biosynthetic process inhibits the synthesis of melanin, which is the basic concept of the whitening cosmetics at present, and the representative raw materials having the whitening function, Ascorbic acid, kojic acid

There have been various uses of kojic acid, arbutin, hydroquinone, and extracts such as mulberry bark extract, topical extract, licorice extract and mulberry extract. In the case of raw materials liberated from natural extracts, But it is still in use because it shows safe results in terms of safety. However, since the whitening raw material of synthetic causes a lot of problems in terms of safety from the viewpoint of safety, it requires a raw material of natural materials excellent in whitening, wrinkling, anti-aging function and in stability.

The present inventors have developed a raw material having a new whitening function, a wrinkle preventing function, and a delayed aging function using natural resources in order to overcome the disadvantages of synthetic whitening raw materials and to develop new safe raw materials. Platanus orientalis L. Platanus is a plant belonging to Platanus. Six species are growing in the northern hemisphere, and the water is strong and the plant is widely planted as a roadside tree and a park. In general, the bark peeled like scales and the fruit runs like a drop. In Korea, P. orientalis , P. occidentalis and P. acerifolia are planted. The most common of these is the pine tree, which is stronger to the cold than the platypus, and smaller in the bark. The leaves are shallowly divided into 3 to 5, and the stipule has wavy sawtooth and is large. The flower is dicotyledonous and the fruit is round.

An object of the present invention is to provide a whitening, wrinkle and anti-aging cosmetic containing Platanus orientalis L. extract.

The present invention relates to cosmetics containing whitening, wrinkling and anti-aging effects containing sycamitol extracts, that is, cosmetics containing sycaments containing water, anhydrous or lower alcohols having 1 to 4 carbon atoms, ethyl acetate, chloroform, n-butanol, , And 3-butylene glycol are added to conventional cosmetic compositions, that is, cosmetic compositions having excellent whitening, wrinkling and anti-aging effects by being added to softening lotion, nutritional lotion, nutritional cream, massage cream, essence, pack and the like. The whitening, wrinkle and anti-aging effects The process for producing the platanus extract contained in cosmetics is as follows. Platanus was washed with purified water, dried, and pulverized using a pulverizer. 1 to 10 times the weight of the powder, 1 to 4 carbon atoms in anhydrous or lower alcohol, acetone, ethyl acetate, chloroform or 1,3-butyleneglycol. After that, the extract was extracted with an extractor, and the extraction temperature was heated at 60 ° C for 12 hours. The extract solution was aged at 4 ° C for 48 hours. The insolubles were removed by passing through No. 1 of Watts, and the extract was concentrated at 50 to 80 ° C using a vacuum concentrator. The suture material of the present invention is added to ordinary softening water (skins), nutritional lotion (milk lotion), nutritional cream, massage cream, essence, pack and the like. The added amount is 0.00001 to 10% by weight, 0.002 to 1% by weight. Hereinafter, the present invention will be described in more detail based on examples. The following examples are given for the purpose of facilitating understanding of the present invention and are not intended to limit the scope of the present invention.

The present invention relates to the development of highly functional cosmetic raw materials containing cosmetic ingredients for whitening, wrinkling and anti-aging (including ultraviolet cutoff) cosmetic ingredients from Platanus orientalis L. ethanol extracts.

Example 1.

1000 g of sycamel powder was placed in an extractor, 3 L of purified water was added, and the mixture was extracted three times at 60 캜 for 12 hours. After extraction, the extract was aged at 4 ° C for 48 hours and filtered using Wattmann No.1. The filtrate was concentrated using a reduced pressure concentrator at a temperature of 50 to 80 ° C

Respectively.

Example 2.

1000 g of sycamel powder was placed in a conditioner and 3 L of ethanol was added thereto, followed by extraction three times at 60 캜 for 12 hours. After extraction, the extract was aged at 4 ° C for 48 hours and filtered using Wattmann No.1. The filtrate was concentrated using a reduced pressure concentrator at a temperature of 50 to 80 ° C

Respectively.

Extraction was carried out in the same manner as in Example 1, and the results are shown in Table 1.

Example Extraction solvent Yield rate (unit: g) One Purified water 100% 120.43 2 10% ethanol 121.14 3 20% ethanol 120.54 4 30% ethanol 121.35 5 40% ethanol 125.36 6 50% ethanol 145.45 7 60% ethanol 186.46 8 70% ethanol 211.48 9 80% ethanol 210.14 10 90% ethanol 221.25 11 100% ethanol 220.45 12 Methanol 210.89 13 Acetone 145.25 14 Ethyl acetate 102.65 15 Cloroform 102.34 16 n-butanol 145.15 17 1,3-butylene glycol 42.35 18 Propylene glycol 45.25 19 Hexane 12.54

The tyrosinase activity inhibitory effect, the elastase activity inhibitory effect and the DPPH effect were measured for the platanus extracts prepared in Examples 1 to 19.

-Terosinase Inhibitory Effect Measuring Method

Tyrosine, and tyrosine SIGMA. The extracts of Examples 1 to 19 were dissolved in methanol and purified water was used for dilution. 70 μl of tyrosinase (125 units / ml) was added to a 96-well plate, and 70 μl of the extract sample was added thereto. The mixture was left at 37 ° C. for 10 minutes in advance. Then, 70 μl of tyrosine (0.1 mg.ml) After half an hour

Absorbance was measured at 475 nm using ELAZER. At this time, the control group was examined by adding purified water instead of each extract.

The tyrosinase inhibitory effect of each extract is obtained by the following formula.

(100 - ((control absorbance - extract absorbance) / control absorbance)) x 100 = inhibition%

- Inhibition of tyrosinase activity of Platanus extract Example Extraction solvent IC ₅₀ = (unit: 占 퐂 / ml) One Purified water 100% 25.68 2 10% ethanol 28.54 3 20% ethanol 29.48 4 30% ethanol 28.64 5 40% ethanol 30.24 6 50% ethanol 25.68 7 60% ethanol 25.34 8 70% ethanol 25.38 9 80% ethanol 25.36 10 90% ethanol 23.25 11 100% ethanol 22.35 12 Methanol 23.54 13 Acetone 56.35 14 Ethyl acetate 45.35 15 Cloroform 254.35 16 n-butanol 102.45 17 1,3-butylene glycol 246.25 18 Propylene glycol 254.35 19 Hexane 450.24

Claims (5)

  Whitening effect, wrinkle suppressing effect, delayed aging effect containing sycamore extract   The cosmetic of claim 1, wherein the sycamant extract is an extract using water, an anhydrous or lower alcohol having 1 to 4 carbon atoms, ethyl acetate, chloroform, n-butanol, 1,3-butylene glycol and other cosmetic moisturizers.   The cosmetic according to claim 1 or 2, wherein the sycamant extract is contained in an amount of 0.0001 to 5% based on the dry weight of the cosmetic.  The cosmetic according to claim 3, which has a formulation of a softening agent, a nutritional lotion, an infant cream, an essence or a pack.   A cosmetic comprising the formulation of the liposome using the sycamore extract of claim 1, the softening lotion containing the powder formulation, the nutritional lotion, the nutritional cream, the essence or the pack.